CL2011002955A1 - Compuestos derivados de 3-[4-(7h-pirrolo[2,3-d]pirimidin-4-il)-1h-pirazol-1-il]octanonitrilo o heptanonitrilo o sus sales, como inhibidores de jak; procedimiento de preparacion; composicion farmaceutica que los comprende; utiles para el tratamiento de trastornos autoinmunes, cancer, entre otras enfermedades. - Google Patents

Compuestos derivados de 3-[4-(7h-pirrolo[2,3-d]pirimidin-4-il)-1h-pirazol-1-il]octanonitrilo o heptanonitrilo o sus sales, como inhibidores de jak; procedimiento de preparacion; composicion farmaceutica que los comprende; utiles para el tratamiento de trastornos autoinmunes, cancer, entre otras enfermedades.

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Publication number
CL2011002955A1
CL2011002955A1 CL2011002955A CL2011002955A CL2011002955A1 CL 2011002955 A1 CL2011002955 A1 CL 2011002955A1 CL 2011002955 A CL2011002955 A CL 2011002955A CL 2011002955 A CL2011002955 A CL 2011002955A CL 2011002955 A1 CL2011002955 A1 CL 2011002955A1
Authority
CL
Chile
Prior art keywords
octanonitrile
heptanonitrile
pyrrolo
pyrazol
pyrimidin
Prior art date
Application number
CL2011002955A
Other languages
English (en)
Spanish (es)
Inventor
Yun-Long Li
James D Rodgers
Original Assignee
Incyte Holdings Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=42246359&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CL2011002955(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Incyte Holdings Corp filed Critical Incyte Holdings Corp
Publication of CL2011002955A1 publication Critical patent/CL2011002955A1/es

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/525—Isoalloxazines, e.g. riboflavins, vitamin B2
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
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    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
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    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

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  • Health & Medical Sciences (AREA)
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  • Endocrinology (AREA)
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  • Dermatology (AREA)
  • Neurology (AREA)
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  • Ophthalmology & Optometry (AREA)
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  • Tropical Medicine & Parasitology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Neurosurgery (AREA)
  • Biotechnology (AREA)
  • Child & Adolescent Psychology (AREA)
CL2011002955A 2009-05-22 2011-11-22 Compuestos derivados de 3-[4-(7h-pirrolo[2,3-d]pirimidin-4-il)-1h-pirazol-1-il]octanonitrilo o heptanonitrilo o sus sales, como inhibidores de jak; procedimiento de preparacion; composicion farmaceutica que los comprende; utiles para el tratamiento de trastornos autoinmunes, cancer, entre otras enfermedades. CL2011002955A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US18058209P 2009-05-22 2009-05-22

Publications (1)

Publication Number Publication Date
CL2011002955A1 true CL2011002955A1 (es) 2012-03-30

Family

ID=42246359

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2011002955A CL2011002955A1 (es) 2009-05-22 2011-11-22 Compuestos derivados de 3-[4-(7h-pirrolo[2,3-d]pirimidin-4-il)-1h-pirazol-1-il]octanonitrilo o heptanonitrilo o sus sales, como inhibidores de jak; procedimiento de preparacion; composicion farmaceutica que los comprende; utiles para el tratamiento de trastornos autoinmunes, cancer, entre otras enfermedades.

Country Status (36)

Country Link
US (3) US8604043B2 (enExample)
EP (2) EP3643312A1 (enExample)
JP (2) JP6172939B2 (enExample)
KR (1) KR20120030447A (enExample)
CN (2) CN106967070A (enExample)
AR (1) AR076920A1 (enExample)
AU (1) AU2010249443B2 (enExample)
BR (1) BRPI1012108B8 (enExample)
CA (1) CA2761954C (enExample)
CL (1) CL2011002955A1 (enExample)
CO (1) CO6470876A2 (enExample)
CR (1) CR20110621A (enExample)
CY (1) CY1122425T1 (enExample)
DK (1) DK2432472T3 (enExample)
EA (1) EA020494B1 (enExample)
EC (1) ECSP11011534A (enExample)
ES (1) ES2761300T3 (enExample)
HR (1) HRP20192203T1 (enExample)
HU (1) HUE046493T2 (enExample)
IL (1) IL216359A (enExample)
LT (1) LT2432472T (enExample)
ME (1) ME03556B (enExample)
MX (1) MX2011012262A (enExample)
MY (1) MY161416A (enExample)
NZ (1) NZ596374A (enExample)
PE (1) PE20120371A1 (enExample)
PL (1) PL2432472T3 (enExample)
PT (1) PT2432472T (enExample)
RS (1) RS59632B1 (enExample)
SG (2) SG176111A1 (enExample)
SI (1) SI2432472T1 (enExample)
SM (1) SMT201900698T1 (enExample)
TW (1) TWI484962B (enExample)
UA (1) UA106078C2 (enExample)
WO (1) WO2010135621A1 (enExample)
ZA (1) ZA201108541B (enExample)

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UA111854C2 (uk) 2011-09-07 2016-06-24 Інсайт Холдінгс Корпорейшн Способи і проміжні сполуки для отримання інгібіторів jak
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AR091079A1 (es) 2012-05-18 2014-12-30 Incyte Corp Derivados de pirrolopirimidina y pirrolopiridina sustituida con piperidinilciclobutilo como inhibidores de jak
PE20151141A1 (es) 2012-11-01 2015-08-06 Incyte Corp Derivados triciclicos fusionados de tiofeno como inhibidores de jak
TW202228704A (zh) 2012-11-15 2022-08-01 美商英塞特控股公司 盧梭利替尼之緩釋性劑型
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