MX2012004180A - Derivados de hidroxil, ceto y glucuronido de 3-(4-7h-pirrolo[2,3-d ]pirimidin-a-il)-1h-pirazol-1-il)-3-ciclopentilpropanonitrilo. - Google Patents

Derivados de hidroxil, ceto y glucuronido de 3-(4-7h-pirrolo[2,3-d ]pirimidin-a-il)-1h-pirazol-1-il)-3-ciclopentilpropanonitrilo.

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Publication number
MX2012004180A
MX2012004180A MX2012004180A MX2012004180A MX2012004180A MX 2012004180 A MX2012004180 A MX 2012004180A MX 2012004180 A MX2012004180 A MX 2012004180A MX 2012004180 A MX2012004180 A MX 2012004180A MX 2012004180 A MX2012004180 A MX 2012004180A
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MX
Mexico
Prior art keywords
pentylpropanenitrile
pyrrolo
pyrazol
pyrimidin
keto
Prior art date
Application number
MX2012004180A
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English (en)
Inventor
James D Rodgers
Argyrios G Arvanitis
Stacey Shepard
Mei Li
Adam Shilling
Laurine G Galya
Frank M Nedza
Original Assignee
Incyte Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Incyte Corp filed Critical Incyte Corp
Publication of MX2012004180A publication Critical patent/MX2012004180A/es

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    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
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    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
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Abstract

La presente invención proporciona derivados de hidroxilo, ceto y glucurónido de 3-(-4(7H-pirrolo [2,3-d] pirimidin-4-il)-1H-pirazol -1il)-3-ciclopentilpropanonitrilo.
MX2012004180A 2009-10-09 2010-10-08 Derivados de hidroxil, ceto y glucuronido de 3-(4-7h-pirrolo[2,3-d ]pirimidin-a-il)-1h-pirazol-1-il)-3-ciclopentilpropanonitrilo. MX2012004180A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US25038709P 2009-10-09 2009-10-09
US31621810P 2010-03-22 2010-03-22
PCT/US2010/052011 WO2011044481A1 (en) 2009-10-09 2010-10-08 Hydroxyl, keto, and glucuronide derivatives of 3-(4-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)-1h-pyrazol-1-yl)-3-cyclopentylpropanenitrile

Publications (1)

Publication Number Publication Date
MX2012004180A true MX2012004180A (es) 2012-07-17

Family

ID=43037845

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2012004180A MX2012004180A (es) 2009-10-09 2010-10-08 Derivados de hidroxil, ceto y glucuronido de 3-(4-7h-pirrolo[2,3-d ]pirimidin-a-il)-1h-pirazol-1-il)-3-ciclopentilpropanonitrilo.

Country Status (14)

Country Link
US (3) US8486902B2 (es)
EP (1) EP2486041B1 (es)
JP (3) JP5946768B2 (es)
KR (3) KR101805936B1 (es)
CN (2) CN105541847B (es)
BR (1) BR112012008267B1 (es)
CA (1) CA2777114C (es)
EA (1) EA021478B1 (es)
ES (1) ES2435491T3 (es)
HK (1) HK1174899A1 (es)
MX (1) MX2012004180A (es)
PL (1) PL2486041T3 (es)
PT (1) PT2486041E (es)
WO (1) WO2011044481A1 (es)

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