CH577480A5 - Alpha-aminophenyl aliphatic carboxylic acids - useful as anti-inflammatory agents, analgesics and anti-mycotics - Google Patents

Alpha-aminophenyl aliphatic carboxylic acids - useful as anti-inflammatory agents, analgesics and anti-mycotics

Info

Publication number
CH577480A5
CH577480A5 CH1383169A CH1383169A CH577480A5 CH 577480 A5 CH577480 A5 CH 577480A5 CH 1383169 A CH1383169 A CH 1383169A CH 1383169 A CH1383169 A CH 1383169A CH 577480 A5 CH577480 A5 CH 577480A5
Authority
CH
Switzerland
Prior art keywords
lower alkyl
group
phenyl
formula
hydrogen
Prior art date
Application number
CH1383169A
Other languages
German (de)
English (en)
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Priority to NL7009387A priority Critical patent/NL170852C/xx
Priority to IL34873A priority patent/IL34873A/xx
Priority to GB3337570A priority patent/GB1316312A/en
Priority to CY811A priority patent/CY811A/xx
Priority to IE899/70A priority patent/IE34380B1/xx
Priority to DE19702034240 priority patent/DE2034240C2/de
Priority to CA087,966A priority patent/CA990299A/en
Priority to PL18795570A priority patent/PL102674B1/pl
Priority to SU1846641A priority patent/SU471715A3/ru
Priority to FR7026096A priority patent/FR2059527B2/fr
Priority to BG021225A priority patent/BG19588A3/xx
Priority to SU1774420A priority patent/SU479283A3/ru
Priority to BG019461A priority patent/BG20099A3/xx
Priority to PL20307370A priority patent/PL103088B1/pl
Priority to BG015202A priority patent/BG20781A3/xx
Priority to PL20307970A priority patent/PL106429B1/pl
Priority to SU1774416A priority patent/SU471714A4/ru
Priority to PL20307270A priority patent/PL103087B1/pl
Priority to PL20307670A priority patent/PL104401B1/pl
Priority to SU1774418A priority patent/SU455529A3/ru
Priority to SU1462497A priority patent/SU458978A3/ru
Priority to PL20307870A priority patent/PL106915B1/pl
Priority to SU1774417A priority patent/SU473357A3/ru
Priority to PL20307470A priority patent/PL103089B1/pl
Priority to SU1768848A priority patent/SU472499A3/ru
Priority to PL20307770A priority patent/PL104897B1/pl
Priority to SU1774421A priority patent/SU460618A3/ru
Priority to BG019462A priority patent/BG20563A3/xx
Priority to PL20307570A priority patent/PL103092B1/pl
Priority to AT130072A priority patent/AT308093B/de
Priority to HUCI1014A priority patent/HU167239B/hu
Priority to AT133972A priority patent/AT308095B/de
Priority to AT134172A priority patent/AT308743B/de
Priority to AT134372A priority patent/AT308096B/de
Priority to OA53986A priority patent/OA149E/xx
Priority to AT129772A priority patent/AT309413B/de
Priority to AT688072A priority patent/AT315163B/de
Priority to AT133872A priority patent/AT308741B/de
Priority to AT129872A priority patent/AT308091B/de
Priority to AT134072A priority patent/AT308742B/de
Priority to AT134272A priority patent/AT308744B/de
Priority to AT133772A priority patent/AT308740B/de
Priority to AT129972A priority patent/AT308092B/de
Priority to AT653570A priority patent/AT309410B/de
Priority to AT129672A priority patent/AT308739B/de
Priority to AT129572A priority patent/AT308738B/de
Priority to BE753600A priority patent/BE753600R/xx
Priority to AT129472A priority patent/AT308737B/de
Priority to AT133672A priority patent/AT308094B/de
Priority to RO7000073290A priority patent/RO62856A/ro
Priority to JP45062579A priority patent/JPS5035076B1/ja
Priority to AR245379A priority patent/AR199095A1/es
Priority to AR245378A priority patent/AR194630A1/es
Priority to AR245380A priority patent/AR198962A1/es
Priority to AR245538A priority patent/AR206495A1/es
Priority to AR245536A priority patent/AR201655A1/es
Priority to AR245537A priority patent/AR200992A1/es
Priority to AR247668A priority patent/AR199480A1/es
Priority to JP13418474A priority patent/JPS5422976B1/ja
Priority to JP13418874A priority patent/JPS556628B1/ja
Priority to JP13419674A priority patent/JPS5344468B1/ja
Priority to JP13419374A priority patent/JPS5432779B1/ja
Priority to JP13419574A priority patent/JPS556629B1/ja
Priority to JP13419474A priority patent/JPS5427333B1/ja
Priority to JP13419774A priority patent/JPS557425B1/ja
Priority to JP13418674A priority patent/JPS5426536B1/ja
Priority to JP13419974A priority patent/JPS5427334B1/ja
Priority to JP13418774A priority patent/JPS556627B1/ja
Priority to JP13419874A priority patent/JPS5344469B1/ja
Priority to JP13418574A priority patent/JPS5425021B1/ja
Priority to JP13419274A priority patent/JPS5432778B1/ja
Priority to JP13418974A priority patent/JPS5432777B1/ja
Priority to JP13419174A priority patent/JPS5422971B1/ja
Priority to JP13419074A priority patent/JPS5422970B1/ja
Priority to KE2544*UA priority patent/KE2544A/xx
Priority to MY150/75A priority patent/MY7500150A/xx
Publication of CH577480A5 publication Critical patent/CH577480A5/de
Priority to JP4791478A priority patent/JPS5536660B1/ja
Priority to JP53101940A priority patent/JPS5745429B1/ja

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • C07D207/263—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms
    • C07D207/27—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms with substituted hydrocarbon radicals directly attached to the ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/20—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/36—Oxygen or sulfur atoms
    • C07D207/40—2,5-Pyrrolidine-diones
    • C07D207/404—2,5-Pyrrolidine-diones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms, e.g. succinimide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/44—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having three double bonds between ring members or between ring members and non-ring members
    • C07D207/444—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having three double bonds between ring members or between ring members and non-ring members having two doubly-bound oxygen atoms directly attached in positions 2 and 5
    • C07D207/448—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having three double bonds between ring members or between ring members and non-ring members having two doubly-bound oxygen atoms directly attached in positions 2 and 5 with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms, e.g. maleimide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/46—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with hetero atoms directly attached to the ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44—Iso-indoles; Hydrogenated iso-indoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44—Iso-indoles; Hydrogenated iso-indoles
    • C07D209/46—Iso-indoles; Hydrogenated iso-indoles with an oxygen atom in position 1
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44—Iso-indoles; Hydrogenated iso-indoles
    • C07D209/48—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/02—Preparation by ring-closure or hydrogenation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/70—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/72—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D211/74—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/72—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D211/78—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/02—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
    • C07D217/04—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines with hydrocarbon or substituted hydrocarbon radicals attached to the ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
    • C07D217/24—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182—Radicals derived from carboxylic acids
    • C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CH1383169A 1968-03-27 1969-09-12 Alpha-aminophenyl aliphatic carboxylic acids - useful as anti-inflammatory agents, analgesics and anti-mycotics CH577480A5 (en)

Priority Applications (78)

Application Number Priority Date Filing Date Title
NL7009387A NL170852C (nl) 1968-03-27 1970-06-25 Werkwijze ter bereiding van farmaceutische preparaten en werkwijze ter bereiding van anti-inflammatoir werkzaam p-isoindolinylfenylazijnzuur en van derivaten hiervan.
IL34873A IL34873A (en) 1969-03-20 1970-07-08 (bicyclic alkenylenimino)phenylaliphatic carboxylic acids and their functional derivatives,their preparation and pharmaceutical compositions containing them
GB3337570A GB1316312A (en) 1968-03-27 1970-07-09 Tertiary aminoacids process for their manufacture and compositions containing them
CY811A CY811A (en) 1969-07-18 1970-07-09 Tertiary aminoacids, process for their manufacture and compositions containing them
IE899/70A IE34380B1 (en) 1969-07-18 1970-07-10 Tertiary aminoacids,process for their manufacture and compositions containing them
DE19702034240 DE2034240C2 (de) 1968-03-27 1970-07-10 Isoindolinderivate, Verfahren zur Herstellung dieser Verbindungen und deren Verwendung
CA087,966A CA990299A (en) 1969-07-18 1970-07-13 Tertiary aminoacids, process for their manufacture and compositions containing them
PL18795570A PL102674B1 (pl) 1969-07-18 1970-07-16 Sposob wytwarzania nowych pochodnych alfa-/aminofenylo/-alifatycznych kwasow karboksylowych
SU1846641A SU471715A3 (ru) 1969-07-18 1970-07-16 Способ получени -(аминофенил)алифатических карбоновых кислот или их солей
FR7026096A FR2059527B2 (en, 2012) 1968-03-27 1970-07-16
BG021225A BG19588A3 (bg) 1969-07-18 1970-07-16 Метод за получаване на терциерни амино-киселини
SU1774420A SU479283A3 (ru) 1969-07-18 1970-07-16 Способ получени -(аминофенил)алифатических карбоновых кислот или их производных,или их солей
BG019461A BG20099A3 (bg) 1969-07-18 1970-07-16 Метод за получаване на терциерни аминокиселини
PL20307370A PL103088B1 (pl) 1969-07-18 1970-07-16 Sposob wytwarzania nowych pochodnych alfa-(aminofenylo)-alifatycznych kwasow karboksylowych
BG015202A BG20781A3 (bg) 1969-07-18 1970-07-16 Метод за получаване на терциерни аминокиселини
PL20307970A PL106429B1 (pl) 1969-07-18 1970-07-16 Sposob wytwarzania nowych pochodnych 2-/aminofenylo/-alifatycznych kwasow karboksylowych
SU1774416A SU471714A4 (ru) 1969-07-18 1970-07-16 Способ получени -(аминофенил)-алифатических карбоновых кислот или их производных,или их солей
PL20307270A PL103087B1 (pl) 1969-07-18 1970-07-16 Sposob wytwarzania nowych pochodnych alfa-(aminofenylo)alifatycznych kwasow karboksylowych
PL20307670A PL104401B1 (pl) 1969-07-18 1970-07-16 Sposob wytwarzania nowych pochodnych alfa-/aminofenylo/-alifatycznych kwasow karboksylowych
SU1774418A SU455529A3 (ru) 1969-07-18 1970-07-16 Способ получени -(аминофенил)-алифатических карбоновых кислот или их производных или их солей
SU1462497A SU458978A3 (ru) 1969-09-12 1970-07-16 Способ получени -(аминофенил)алифатических карбоновых кислот
PL20307870A PL106915B1 (pl) 1969-07-18 1970-07-16 Sposob wytwarzania nowych pochodnych alfa-/aminofenylo/-alifatycznych kwasow karboksylowych
SU1774417A SU473357A3 (ru) 1969-07-18 1970-07-16 Способ получени -(аминофенил)алифатических карбоновых кислот или их производных,или их солей
PL20307470A PL103089B1 (pl) 1969-07-18 1970-07-16 Sposob wytwarzania nowych pochodnych alfa-/aminofenylo/-alifatycznych kwasow karboksylowych
SU1768848A SU472499A3 (ru) 1969-07-18 1970-07-16 Способ получени -(аминофенил)-алифатических карбоновых кислот или их производных или солей
PL20307770A PL104897B1 (pl) 1969-07-18 1970-07-16 Sposob wytwarzania nowych pochodnych alfa-/aminofenylo/-alifatycznych kwasow karboksylowych
SU1774421A SU460618A3 (ru) 1969-07-18 1970-07-16 Способ получени (аминофенил) -алифатеических карбоновых кислот или их производных, или их солей
BG019462A BG20563A3 (bg) 1969-07-18 1970-07-16 Метод за получаване на терциерни амино-киселини
PL20307570A PL103092B1 (pl) 1969-07-18 1970-07-16 Sposob wytwarzania nowych pochodnych alfa-(aminofenylo)-alifatycznych kwasow karboksylowych
AT130072A AT308093B (de) 1969-07-18 1970-07-17 Verfahren zur herstellung neuer heterocyclischer verbindungen und ihrer salze
HUCI1014A HU167239B (en, 2012) 1969-07-18 1970-07-17
AT133972A AT308095B (de) 1969-07-18 1970-07-17 Verfahren zur herstellung neuer heterocyclischer verbindungen und ihrer salze
AT134172A AT308743B (de) 1968-03-27 1970-07-17 Verfahren zur Herstellung neuer heterocyclischer Verbindungen und ihrer Salze
AT134372A AT308096B (de) 1969-07-18 1970-07-17 Verfahren zur herstellung neuer heterocyclischer verbindungen und ihrer salze
OA53986A OA149E (en, 2012) 1969-07-18 1970-07-17
AT129772A AT309413B (de) 1969-07-18 1970-07-17 Verfahren zur Herstellung neuer heterocyclischer Verbindungen und ihrer Salze
AT688072A AT315163B (de) 1969-07-18 1970-07-17 Verfahren zur Herstellung neuer heterocyclischer Verbindungen und ihrer Salze
AT133872A AT308741B (de) 1969-07-18 1970-07-17 Verfahren zur Herstellung neuer heterocyclischer Verbindungen und ihrer Salze
AT129872A AT308091B (de) 1969-07-18 1970-07-17 Verfahren zur herstellung neuer heterocyclischer verbindungen und ihrer salze
AT134072A AT308742B (de) 1968-03-27 1970-07-17 Verfahren zur Herstellung neuer heterocyclischer Verbindungen oder Salze davon
AT134272A AT308744B (de) 1969-07-18 1970-07-17 Verfahren zur Herstellung neuer heterocyclischer Verbindungen und ihrer Salze
AT133772A AT308740B (de) 1969-07-18 1970-07-17 Verfahren zur Herstellung neuer heterocyclischer Verbindungen und ihrer Salze
AT129972A AT308092B (de) 1969-07-18 1970-07-17 Verfahren zur herstellung neuer heterocyclischer verbindungen und ihrer salze
AT653570A AT309410B (de) 1969-07-18 1970-07-17 Verfahren zur Herstellung neuer heterocyclischer Verbindungen und ihrer Salze
AT129672A AT308739B (de) 1969-09-12 1970-07-17 Verfahren zur Herstellung neuer heterocyclischer Verbindungen und ihrer Salze
AT129572A AT308738B (de) 1969-07-18 1970-07-17 Verfahren zur Herstellung neuer heterocyclischer Verbindungen und ihrer Salze
BE753600A BE753600R (fr) 1968-03-27 1970-07-17 Amino-acides
AT129472A AT308737B (de) 1969-07-18 1970-07-17 Verfahren zur Herstellung neuer heterocyclischer Verbindungen und ihrer Salze
AT133672A AT308094B (de) 1969-07-18 1970-07-17 Verfahren zur herstellung neuer heterocyclischer verbindungen und ihrer salze
RO7000073290A RO62856A (fr) 1969-07-18 1970-07-18 Procede pour la preparation des aminoacides tertiaires
JP45062579A JPS5035076B1 (en, 2012) 1969-07-18 1970-07-18
AR245379A AR199095A1 (es) 1969-07-18 1972-11-29 Procedimiento para la elaboracion de compuestos de acidos carboxilicos alfa-(amino-fenil)-alifaticos
AR245378A AR194630A1 (es) 1969-07-18 1972-11-29 Procedimiento para obtener compuestos de acidos carboxilicos alfa(amino-fenil)alifaticos
AR245380A AR198962A1 (es) 1969-07-18 1972-11-29 Procedimiento para la elaboracion de compuestos de acidos carboxilicos alpha - (amino-fenil)-alifaticos
AR245538A AR206495A1 (es) 1969-07-18 1972-12-07 Procedimiento para la elaboracion de nuevos acidos carboxilicos alpha-(2-isoindolinil-o 1,2,3,4-tetrahidro-2-isoquinolil-fenil)-alifaticos
AR245536A AR201655A1 (es) 1969-07-18 1972-12-07 Procedimiento para la elaboracion de compuestos de acidos carboxilicos alfa-(amino-fenli)-alifaticos
AR245537A AR200992A1 (es) 1969-07-18 1972-12-07 Procedimiento para la elaboracion de compuestos de alpha-(aminofenil-alifaticos del acidocarboxilico, o sus sales
AR247668A AR199480A1 (es) 1969-07-18 1973-04-24 Procedimiento para la elaboracion de nuevos acidos carboxilicos alfa-(amino-fenil)-alifaticos y sus derivados funcionales
JP13418474A JPS5422976B1 (en, 2012) 1969-07-18 1974-11-21
JP13418874A JPS556628B1 (en, 2012) 1969-07-18 1974-11-21
JP13419674A JPS5344468B1 (en, 2012) 1969-07-18 1974-11-21
JP13419374A JPS5432779B1 (en, 2012) 1969-07-18 1974-11-21
JP13419574A JPS556629B1 (en, 2012) 1969-07-18 1974-11-21
JP13419474A JPS5427333B1 (en, 2012) 1969-07-18 1974-11-21
JP13419774A JPS557425B1 (en, 2012) 1969-07-18 1974-11-21
JP13418674A JPS5426536B1 (en, 2012) 1969-07-18 1974-11-21
JP13419974A JPS5427334B1 (en, 2012) 1969-07-18 1974-11-21
JP13418774A JPS556627B1 (en, 2012) 1969-07-18 1974-11-21
JP13419874A JPS5344469B1 (en, 2012) 1969-07-18 1974-11-21
JP13418574A JPS5425021B1 (en, 2012) 1969-07-18 1974-11-21
JP13419274A JPS5432778B1 (en, 2012) 1969-07-18 1974-11-21
JP13418974A JPS5432777B1 (en, 2012) 1969-07-18 1974-11-21
JP13419174A JPS5422971B1 (en, 2012) 1969-07-18 1974-11-21
JP13419074A JPS5422970B1 (en, 2012) 1969-07-18 1974-11-21
KE2544*UA KE2544A (en) 1969-07-18 1975-07-10 Tertiary aminoacids, process for their manufacture and compositions containing them
MY150/75A MY7500150A (en) 1969-07-18 1975-12-30 Tertiary aminoacids, process for their manufacture and compositions containing them
JP4791478A JPS5536660B1 (en, 2012) 1969-07-18 1978-04-24
JP53101940A JPS5745429B1 (en, 2012) 1969-07-18 1978-08-23

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US84324469A 1969-07-18 1969-07-18

Publications (1)

Publication Number Publication Date
CH577480A5 true CH577480A5 (en) 1976-07-15

Family

ID=25289436

Family Applications (13)

Application Number Title Priority Date Filing Date
CH1383169A CH577480A5 (en) 1968-03-27 1969-09-12 Alpha-aminophenyl aliphatic carboxylic acids - useful as anti-inflammatory agents, analgesics and anti-mycotics
CH935375A CH577482A5 (en, 2012) 1969-07-18 1969-09-12
CH935275A CH577481A5 (en, 2012) 1969-07-18 1969-09-12
CH935475A CH605792A5 (en, 2012) 1969-07-18 1975-07-16
CH1383169A CH579548A5 (en, 2012) 1969-07-18 1975-07-16
CH1383169A CH585722A5 (en, 2012) 1969-07-18 1975-07-16
CH1383169A CH585724A5 (en, 2012) 1969-07-18 1975-07-16
CH1383169A CH585727A5 (en, 2012) 1969-07-18 1975-07-16
CH1383169A CH585723A5 (en, 2012) 1969-07-18 1975-07-16
CH1383169A CH579541A5 (en, 2012) 1969-07-18 1975-07-16
CH1383169A CH585726A5 (en, 2012) 1969-07-18 1975-07-16
CH1383169A CH584690A5 (en, 2012) 1969-07-18 1975-07-16
CH1383169A CH585725A5 (en, 2012) 1969-07-18 1975-07-16

Family Applications After (12)

Application Number Title Priority Date Filing Date
CH935375A CH577482A5 (en, 2012) 1969-07-18 1969-09-12
CH935275A CH577481A5 (en, 2012) 1969-07-18 1969-09-12
CH935475A CH605792A5 (en, 2012) 1969-07-18 1975-07-16
CH1383169A CH579548A5 (en, 2012) 1969-07-18 1975-07-16
CH1383169A CH585722A5 (en, 2012) 1969-07-18 1975-07-16
CH1383169A CH585724A5 (en, 2012) 1969-07-18 1975-07-16
CH1383169A CH585727A5 (en, 2012) 1969-07-18 1975-07-16
CH1383169A CH585723A5 (en, 2012) 1969-07-18 1975-07-16
CH1383169A CH579541A5 (en, 2012) 1969-07-18 1975-07-16
CH1383169A CH585726A5 (en, 2012) 1969-07-18 1975-07-16
CH1383169A CH584690A5 (en, 2012) 1969-07-18 1975-07-16
CH1383169A CH585725A5 (en, 2012) 1969-07-18 1975-07-16

Country Status (8)

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CH (13) CH577480A5 (en, 2012)
ES (1) ES381910A2 (en, 2012)
FI (1) FI54106C (en, 2012)
NO (1) NO135938C (en, 2012)
PL (6) PL116578B1 (en, 2012)
SE (1) SE394670B (en, 2012)
SU (1) SU520040A3 (en, 2012)
ZA (1) ZA704666B (en, 2012)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12195552B2 (en) 2018-12-17 2025-01-14 Remegen Co., Ltd. Linker for antibody-drug conjugates and its use

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SU520040A3 (ru) 1976-06-30
FI54106B (fi) 1978-06-30
NO135938B (en, 2012) 1977-03-21
PL99355B1 (pl) 1978-07-31
CH584690A5 (en, 2012) 1977-02-15
CH577482A5 (en, 2012) 1976-07-15
CH585725A5 (en, 2012) 1977-03-15
CH577481A5 (en, 2012) 1976-07-15
CH579541A5 (en, 2012) 1976-09-15
FI54106C (fi) 1978-10-10
CH605792A5 (en, 2012) 1978-10-13
PL116578B1 (en) 1981-06-30
SE394670B (sv) 1977-07-04
PL116729B1 (en) 1981-06-30
PL97082B3 (en) 1978-02-28
NO135938C (en, 2012) 1977-06-29
PL116504B1 (en) 1981-06-30
ZA704666B (en) 1971-03-31
CH585722A5 (en, 2012) 1977-03-15
CH585727A5 (en, 2012) 1977-03-15
CH579548A5 (en, 2012) 1976-09-15
CH585724A5 (en, 2012) 1977-03-15
CH585726A5 (en, 2012) 1977-03-15
CH585723A5 (en, 2012) 1977-03-15
ES381910A2 (es) 1973-01-16
PL99354B1 (pl) 1978-07-31

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