AR206495A1 - Procedimiento para la elaboracion de nuevos acidos carboxilicos alpha-(2-isoindolinil-o 1,2,3,4-tetrahidro-2-isoquinolil-fenil)-alifaticos - Google Patents

Procedimiento para la elaboracion de nuevos acidos carboxilicos alpha-(2-isoindolinil-o 1,2,3,4-tetrahidro-2-isoquinolil-fenil)-alifaticos

Info

Publication number
AR206495A1
AR206495A1 AR245538A AR24553872A AR206495A1 AR 206495 A1 AR206495 A1 AR 206495A1 AR 245538 A AR245538 A AR 245538A AR 24553872 A AR24553872 A AR 24553872A AR 206495 A1 AR206495 A1 AR 206495A1
Authority
AR
Argentina
Prior art keywords
isoindolinil
alipaticos
isoquinolil
tetrahidro
fenil
Prior art date
Application number
AR245538A
Other languages
English (en)
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CH1383169A external-priority patent/CH577480A5/de
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Application granted granted Critical
Publication of AR206495A1 publication Critical patent/AR206495A1/es

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24Oxygen or sulfur atoms
    • C07D207/262-Pyrrolidones
    • C07D207/2632-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms
    • C07D207/272-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms with substituted hydrocarbon radicals directly attached to the ring nitrogen atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/49Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups
    • C07C205/56Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups having nitro groups bound to carbon atoms of six-membered aromatic rings and carboxyl groups bound to acyclic carbon atoms of the carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/20Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/36Oxygen or sulfur atoms
    • C07D207/402,5-Pyrrolidine-diones
    • C07D207/4042,5-Pyrrolidine-diones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms, e.g. succinimide
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/44Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having three double bonds between ring members or between ring members and non-ring members
    • C07D207/444Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having three double bonds between ring members or between ring members and non-ring members having two doubly-bound oxygen atoms directly attached in positions 2 and 5
    • C07D207/448Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having three double bonds between ring members or between ring members and non-ring members having two doubly-bound oxygen atoms directly attached in positions 2 and 5 with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms, e.g. maleimide
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/46Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with hetero atoms directly attached to the ring nitrogen atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44Iso-indoles; Hydrogenated iso-indoles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44Iso-indoles; Hydrogenated iso-indoles
    • C07D209/46Iso-indoles; Hydrogenated iso-indoles with an oxygen atom in position 1
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44Iso-indoles; Hydrogenated iso-indoles
    • C07D209/48Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/02Preparation by ring-closure or hydrogenation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/70Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/72Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D211/74Oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/72Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D211/78Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D217/00Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/02Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
    • C07D217/04Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines with hydrocarbon or substituted hydrocarbon radicals attached to the ring nitrogen atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D217/00Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/22Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
    • C07D217/24Oxygen atoms
AR245538A 1969-07-18 1972-12-07 Procedimiento para la elaboracion de nuevos acidos carboxilicos alpha-(2-isoindolinil-o 1,2,3,4-tetrahidro-2-isoquinolil-fenil)-alifaticos AR206495A1 (es)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US84324469A 1969-07-18 1969-07-18
US85615469A 1969-09-08 1969-09-08
CH1383169A CH577480A5 (en) 1969-07-18 1969-09-12 Alpha-aminophenyl aliphatic carboxylic acids - useful as anti-inflammatory agents, analgesics and anti-mycotics
US840670A 1970-02-03 1970-02-03
US4043670A 1970-05-25 1970-05-25

Publications (1)

Publication Number Publication Date
AR206495A1 true AR206495A1 (es) 1976-07-30

Family

ID=27509487

Family Applications (7)

Application Number Title Priority Date Filing Date
AR245380A AR198962A1 (es) 1969-07-18 1972-11-29 Procedimiento para la elaboracion de compuestos de acidos carboxilicos alpha - (amino-fenil)-alifaticos
AR245378A AR194630A1 (es) 1969-07-18 1972-11-29 Procedimiento para obtener compuestos de acidos carboxilicos alfa(amino-fenil)alifaticos
AR245379A AR199095A1 (es) 1969-07-18 1972-11-29 Procedimiento para la elaboracion de compuestos de acidos carboxilicos alfa-(amino-fenil)-alifaticos
AR245537A AR200992A1 (es) 1969-07-18 1972-12-07 Procedimiento para la elaboracion de compuestos de alpha-(aminofenil-alifaticos del acidocarboxilico, o sus sales
AR245538A AR206495A1 (es) 1969-07-18 1972-12-07 Procedimiento para la elaboracion de nuevos acidos carboxilicos alpha-(2-isoindolinil-o 1,2,3,4-tetrahidro-2-isoquinolil-fenil)-alifaticos
AR245536A AR201655A1 (es) 1969-07-18 1972-12-07 Procedimiento para la elaboracion de compuestos de acidos carboxilicos alfa-(amino-fenli)-alifaticos
AR247668A AR199480A1 (es) 1969-07-18 1973-04-24 Procedimiento para la elaboracion de nuevos acidos carboxilicos alfa-(amino-fenil)-alifaticos y sus derivados funcionales

Family Applications Before (4)

Application Number Title Priority Date Filing Date
AR245380A AR198962A1 (es) 1969-07-18 1972-11-29 Procedimiento para la elaboracion de compuestos de acidos carboxilicos alpha - (amino-fenil)-alifaticos
AR245378A AR194630A1 (es) 1969-07-18 1972-11-29 Procedimiento para obtener compuestos de acidos carboxilicos alfa(amino-fenil)alifaticos
AR245379A AR199095A1 (es) 1969-07-18 1972-11-29 Procedimiento para la elaboracion de compuestos de acidos carboxilicos alfa-(amino-fenil)-alifaticos
AR245537A AR200992A1 (es) 1969-07-18 1972-12-07 Procedimiento para la elaboracion de compuestos de alpha-(aminofenil-alifaticos del acidocarboxilico, o sus sales

Family Applications After (2)

Application Number Title Priority Date Filing Date
AR245536A AR201655A1 (es) 1969-07-18 1972-12-07 Procedimiento para la elaboracion de compuestos de acidos carboxilicos alfa-(amino-fenli)-alifaticos
AR247668A AR199480A1 (es) 1969-07-18 1973-04-24 Procedimiento para la elaboracion de nuevos acidos carboxilicos alfa-(amino-fenil)-alifaticos y sus derivados funcionales

Country Status (11)

Country Link
JP (19) JPS5035076B1 (es)
AR (7) AR198962A1 (es)
BG (4) BG20099A3 (es)
CA (1) CA990299A (es)
CY (1) CY811A (es)
HU (1) HU167239B (es)
IE (1) IE34380B1 (es)
KE (1) KE2544A (es)
MY (1) MY7500150A (es)
OA (1) OA149E (es)
RO (1) RO62856A (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2017053787A (ja) 2015-09-11 2017-03-16 株式会社デンソー 空気流量測定装置

Also Published As

Publication number Publication date
JPS5426536B1 (es) 1979-09-04
JPS5427333B1 (es) 1979-09-10
HU167239B (es) 1975-09-27
IE34380B1 (en) 1975-04-30
AR198962A1 (es) 1974-07-31
RO62856A (fr) 1978-01-15
JPS5427334B1 (es) 1979-09-10
JPS557425B1 (es) 1980-02-25
AR200992A1 (es) 1975-02-06
BG20099A3 (es) 1975-10-30
CA990299A (en) 1976-06-01
BG20781A3 (es) 1975-12-20
JPS5536660B1 (es) 1980-09-22
JPS5344468B1 (es) 1978-11-29
JPS5344469B1 (es) 1978-11-29
KE2544A (en) 1975-07-25
AR199095A1 (es) 1974-08-08
MY7500150A (en) 1975-12-31
JPS5745429B1 (es) 1982-09-28
AR201655A1 (es) 1975-04-08
AR194630A1 (es) 1973-07-31
JPS5422970B1 (es) 1979-08-10
BG20563A3 (es) 1975-12-05
BG19588A3 (es) 1975-06-25
IE34380L (en) 1971-01-18
JPS5432777B1 (es) 1979-10-16
JPS5432779B1 (es) 1979-10-16
JPS556627B1 (es) 1980-02-18
AR199480A1 (es) 1974-09-09
JPS5425021B1 (es) 1979-08-24
CY811A (en) 1976-12-01
OA149E (es) 1971-12-24
JPS5422971B1 (es) 1979-08-10
JPS5432778B1 (es) 1979-10-16
JPS5035076B1 (es) 1975-11-13
JPS556628B1 (es) 1980-02-18
JPS5422976B1 (es) 1979-08-10
JPS556629B1 (es) 1980-02-18

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