CA3012229C - 1,2,5-oxadiazoles as inhibitors of indoleamine 2,3-dioxygenase - Google Patents
1,2,5-oxadiazoles as inhibitors of indoleamine 2,3-dioxygenase Download PDFInfo
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- CA3012229C CA3012229C CA3012229A CA3012229A CA3012229C CA 3012229 C CA3012229 C CA 3012229C CA 3012229 A CA3012229 A CA 3012229A CA 3012229 A CA3012229 A CA 3012229A CA 3012229 C CA3012229 C CA 3012229C
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- oxadiazol
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| CA2743975A CA2743975C (en) | 2008-07-08 | 2009-07-07 | 1,2,5-oxadiazoles as inhibitors of indoleamine 2,3-dioxygenase |
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| CA2743975A Division CA2743975C (en) | 2008-07-08 | 2009-07-07 | 1,2,5-oxadiazoles as inhibitors of indoleamine 2,3-dioxygenase |
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| US8299295B2 (en) | 2009-10-15 | 2012-10-30 | Johnson Matthey Public Limited Company | Polymorphs of bromfenac sodium and methods for preparing bromfenac sodium polymorphs |
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| EP2781517B1 (en) | 2011-11-09 | 2017-10-11 | Kyowa Hakko Kirin Co., Ltd. | Nitrogen-containing heterocyclic compound |
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| SG11201408679XA (en) | 2012-06-26 | 2015-01-29 | Del Mar Pharmaceuticals | Methods for treating tyrosine-kinase-inhibitor-resistant malignancies in patients with genetic polymorphisms or ahi1 dysregulations or mutations employing dianhydrogalactitol, diacetyldianhydrogalactitol, dibromodulcitol, or analogs or derivatives thereof |
| WO2014066834A1 (en) | 2012-10-26 | 2014-05-01 | The University Of Chicago | Synergistic combination of immunologic inhibitors for the treatment of cancer |
| US11491154B2 (en) | 2013-04-08 | 2022-11-08 | Dennis M. Brown | Therapeutic benefit of suboptimally administered chemical compounds |
| CR20160252A (es) * | 2013-11-08 | 2016-09-19 | Incyte Holdings Corp | Proceso para la sintesis de un inhibidor de indolamina 2,3-dioxigenasa |
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| JP6637439B2 (ja) | 2014-03-31 | 2020-01-29 | ジェネンテック， インコーポレイテッド | 抗ｏｘ４０抗体及び使用方法 |
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| PH12016502345B1 (en) | 2014-05-28 | 2023-03-01 | Agenus Inc | Anti-gitr antibodies and methods of use thereof |
| EP3151820A4 (en) | 2014-06-06 | 2017-11-22 | Flexus Biosciences, Inc. | Immunoregulatory agents |
| CN114588157A (zh) * | 2014-07-17 | 2022-06-07 | Chdi基金会股份有限公司 | 用于治疗hiv相关病症的方法和组合物 |
| CN105481789B (zh) * | 2014-09-15 | 2020-05-19 | 中国科学院上海有机化学研究所 | 一种吲哚胺-2,3-双加氧酶抑制剂及其制备方法 |
| UY36391A (es) | 2014-11-05 | 2016-06-01 | Flexus Biosciences Inc | Compuestos moduladores de la enzima indolamina 2,3-dioxigenasa (ido1), sus métodos de síntesis y composiciones farmacèuticas que las contienen |
| WO2016073738A2 (en) | 2014-11-05 | 2016-05-12 | Flexus Biosciences, Inc. | Immunoregulatory agents |
| UY36390A (es) | 2014-11-05 | 2016-06-01 | Flexus Biosciences Inc | Compuestos moduladores de la enzima indolamina 2,3-dioxigenasa (ido), sus métodos de síntesis y composiciones farmacéuticas que los contienen |
| US10525035B2 (en) | 2014-12-18 | 2020-01-07 | Lankenau Institute For Medical Research | Methods and compositions for the treatment of retinopathy and other ocular diseases |
| WO2016123573A1 (en) | 2015-01-30 | 2016-08-04 | President And Fellows Of Harvard College | Peritumoral and intratumoral materials for cancer therapy |
| KR102394917B1 (ko) | 2015-03-04 | 2022-05-09 | 길리애드 사이언시즈, 인코포레이티드 | 톨 유사 수용체 조정제 화합물 |
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| CN106660974B (zh) * | 2015-03-31 | 2019-08-30 | 江苏恒瑞医药股份有限公司 | 含氨磺酰基的1,2,5-噁二唑类衍生物、其制备方法及其在医药上的应用 |
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| AU2016250976B2 (en) | 2015-04-21 | 2020-02-27 | Jiangsu Hengrui Medicine Co., Ltd. | Imidazo isoindole derivative, preparation method therefor and medical use thereof |
| MA44594B1 (fr) | 2015-05-29 | 2020-09-30 | Memorial Sloan Kettering Cancer Center | Anticorps anti-ctla-4 et méthodes d'utilisation de ceux-ci |
| US9891882B2 (en) * | 2015-06-01 | 2018-02-13 | Nagravision S.A. | Methods and systems for conveying encrypted data to a communication device |
| KR20180025888A (ko) | 2015-06-08 | 2018-03-09 | 제넨테크, 인크. | 항-ox40 항체 및 pd-1 축 결합 길항제를 사용하여 암을 치료하는 방법 |
| HK1252272A1 (zh) | 2015-06-08 | 2019-05-24 | 豪夫迈‧罗氏有限公司 | 使用抗ox40抗体治疗癌症的方法 |
| EP3317287B1 (en) * | 2015-07-02 | 2019-07-31 | GlaxoSmithKline Intellectual Property Development Limited | Inhibitors of indoleamine 2,3-dioxygenase |
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