BR9909409A - Processo para produzir bactérias corineformes tendo uma melhorada produtividade de aminoácido ou ácido nucleico, genes sintetizando ácido glutâmico, e arginina sintetase, bactérias corineformes produzindo ácido glutâmico, e produzindo arginina e, processos para produzir um aminoácido ou ácido nucleico por fermentação, e para produzir ácido l-glutâmico por fermentação. - Google Patents

Processo para produzir bactérias corineformes tendo uma melhorada produtividade de aminoácido ou ácido nucleico, genes sintetizando ácido glutâmico, e arginina sintetase, bactérias corineformes produzindo ácido glutâmico, e produzindo arginina e, processos para produzir um aminoácido ou ácido nucleico por fermentação, e para produzir ácido l-glutâmico por fermentação.

Info

Publication number
BR9909409A
BR9909409A BR9909409-6A BR9909409A BR9909409A BR 9909409 A BR9909409 A BR 9909409A BR 9909409 A BR9909409 A BR 9909409A BR 9909409 A BR9909409 A BR 9909409A
Authority
BR
Brazil
Prior art keywords
producing
acid
nucleic acid
amino acid
glutamic
Prior art date
Application number
BR9909409-6A
Other languages
English (en)
Other versions
BRPI9909409B1 (pt
Inventor
Yoko Asakura
Jun Nakamura
Sohei Kanno
Mikiko Suga
Eiichiro Kimura
Hisao Ito
Kazuhiko Matsui
Tsuyoshi Ohsumi
Tsuyoshi Nakamatsu
Osamu Kurahashi
Original Assignee
Ajinomoto Kk
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26549879&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BR9909409(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Ajinomoto Kk filed Critical Ajinomoto Kk
Publication of BR9909409A publication Critical patent/BR9909409A/pt
Publication of BRPI9909409B1 publication Critical patent/BRPI9909409B1/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/14—Glutamic acid; Glutamine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/67—General methods for enhancing the expression

Landscapes

  • Genetics & Genomics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Plant Pathology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

"PROCESSO PARA PRODUZIR BACTéRIAS CORINEFORMES TENDO UMA MELHORADA PRODUTIVIDADE DE AMINOáCIDO OU áCIDO NUCLEICO, GENES SINTETIZANDO áCIDO GLUTâMICO, E ARGININA SINTETASE, BACTéRIAS CORINEFORMES PRODUZINDO áCIDO GLUTâMICO, E PRODUZINDO ARGININA, E, PROCESSOS PARA PRODUZIR UM AMINOáCIDO OU áCIDO NUCLEICO POR FERMENTAçãO, E PARA PRODUZIR áCIDO L-GLUTâMICO POR FERMENTAçãO". Um processo para produzir bactérias corineformes tendo uma melhorada produtividade de aminoácido ou ácido nucleico compreende as etapas de introduzir uma mutação em uma seq³ência de promotor de genes bio-sintetizando aminoácido ou ácido nucleico em um cromossomo de uma bactéria corineforme para o tornar mais próxima de uma seq³ência de consenso ou introduzir uma mudança em uma seq³ência de promotor de genes biosintetizando aminoácido ou ácido nucleico em um cromossomo de uma bactéria corineforme por recombinação de genes, para a tornar mais próxima de uma seq³ência de consenso, para obter mutantes de microorganismo produzindo aminoácido ou ácido nucleico corineforme, cultivar os mutantes e selecionar um mutante capaz de produzir o aminoácido ou ácido nucleico pretendido em uma grande quantidade. Este processo pode construir um mutante capaz de enriquecer ou controlar de modo apropriado a expressão de um gene pretendido sem usar um plasmídeo e também capaz de produzir aminoácidos em um alto rendimento, pela recombinação ou mutação.
BRPI9909409A 1998-09-25 1999-09-22 processos para produzir um ácido l-glutâmico BRPI9909409B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP27178698 1998-09-25
JP27178798 1998-09-25
PCT/JP1999/005175 WO2000018935A1 (fr) 1998-09-25 1999-09-22 Procede de construction d'une bacterie produisant des acides amines, et procede de production d'acides amines par une technique de fermentation utilisant ladite bacterie

Publications (2)

Publication Number Publication Date
BR9909409A true BR9909409A (pt) 2000-11-21
BRPI9909409B1 BRPI9909409B1 (pt) 2016-03-22

Family

ID=26549879

Family Applications (2)

Application Number Title Priority Date Filing Date
BRPI9917880-0A BR9917880B1 (pt) 1998-09-25 1999-09-22 Processo para produzir um ácido l-glutâmico
BRPI9909409A BRPI9909409B1 (pt) 1998-09-25 1999-09-22 processos para produzir um ácido l-glutâmico

Family Applications Before (1)

Application Number Title Priority Date Filing Date
BRPI9917880-0A BR9917880B1 (pt) 1998-09-25 1999-09-22 Processo para produzir um ácido l-glutâmico

Country Status (16)

Country Link
US (2) US6962805B2 (pt)
EP (1) EP1033407B1 (pt)
KR (1) KR100630604B1 (pt)
CN (1) CN1170938C (pt)
AT (1) ATE447039T1 (pt)
BR (2) BR9917880B1 (pt)
DE (1) DE69941594D1 (pt)
ES (1) ES2335828T3 (pt)
HU (2) HU225541B1 (pt)
ID (1) ID25513A (pt)
MY (1) MY130756A (pt)
PE (1) PE20001111A1 (pt)
RU (1) RU2214456C2 (pt)
SK (1) SK7702000A3 (pt)
TW (4) TWI247805B (pt)
WO (1) WO2000018935A1 (pt)

Families Citing this family (135)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX9709923A (es) 1995-06-07 1998-03-31 Ajinomoto Kk Metodo de produccion de l-lisina.
ES2335828T3 (es) 1998-09-25 2010-04-05 Ajinomoto Co., Inc. Bacterias corineformes para producir l-glu.
AU2001285833A1 (en) * 2000-07-24 2002-02-05 Degussa A.G. Process for the fermentative preparation of l-glutamic acid using coryneform bacteria
CN1181190C (zh) * 2000-11-17 2004-12-22 第一制糖株式会社 产生l-谷氨酰胺的微生物和使用该微生物产生l-谷氨酰胺的方法
BR0304860A (pt) * 2002-11-11 2004-08-31 Ajinomoto Kk Método para produzir uma substância alvo pela utilização de uma-bactéria pertencente ao gênero escherichia
EP1424397B1 (en) 2002-11-26 2011-01-19 Ajinomoto Co., Inc. Method for producing L-glutamine and L-glutamine producing bacterium
DE10359594A1 (de) * 2003-12-18 2005-07-28 Basf Ag PEF-TU-Expressionseinheiten
KR100786987B1 (ko) * 2004-01-30 2007-12-18 아지노모토 가부시키가이샤 Ｌ-아미노산 생산 미생물 및 ｌ-아미노산 생산 방법
BRPI0509056A (pt) 2004-03-31 2007-08-21 Ajinomoto Kk bactéria pertencendo ao gênero bacillus ou ao gênero escherichia, e, métodos para produzir um nucleosìdeo de purina, para produzir um nucleotìdeo de purina e para produzir ácido 5'-guanìlico
DE102004035065A1 (de) * 2004-07-20 2006-02-16 Basf Ag P-ET-TS-Expressionseinheiten
JP2006063002A (ja) * 2004-08-25 2006-03-09 Ajinomoto Co Inc 反芻動物用のメタン生成抑制剤および飼料用組成物
EP2602320B1 (en) * 2004-10-13 2016-11-30 Mitsui Chemicals, Inc. DNA encoding novel enzyme having D-serine synthase activity, method of producing the enzyme and method of producing D-serine by using the same
JP4595506B2 (ja) * 2004-11-25 2010-12-08 味の素株式会社 Ｌ−アミノ酸生産菌及びｌ−アミノ酸の製造方法
KR100620092B1 (ko) * 2004-12-16 2006-09-08 씨제이 주식회사 코리네박테리움 속 세포로부터 유래된 신규한 프로모터서열, 그를 포함하는 발현 카세트 및 벡터, 상기 벡터를포함하는 숙주 세포 및 그를 이용하여 유전자를 발현하는방법
US7794989B2 (en) * 2004-12-28 2010-09-14 Ajinomoto Co., Inc. L-glutamic acid-producing microorganism and a method for producing L-glutamic acid
BRPI0519410B1 (pt) 2004-12-28 2020-12-22 Ajinomoto Co., Inc método para produzir ácido l-glutâmico
US7326546B2 (en) 2005-03-10 2008-02-05 Ajinomoto Co., Inc. Purine-derived substance-producing bacterium and a method for producing purine-derived substance
TWI361834B (en) 2005-04-12 2012-04-11 Kyowa Hakko Bio Co Ltd A method for producing amino acids
US7781191B2 (en) * 2005-04-12 2010-08-24 E. I. Du Pont De Nemours And Company Treatment of biomass to obtain a target chemical
WO2006110901A2 (en) * 2005-04-12 2006-10-19 E. I. Du Pont De Nemours And Company Treatment of biomass to obtain fermentable sugars
US20070029252A1 (en) * 2005-04-12 2007-02-08 Dunson James B Jr System and process for biomass treatment
JP2008283863A (ja) * 2005-08-26 2008-11-27 Ajinomoto Co Inc Ｌ−アミノ酸生産菌及びｌ−アミノ酸の製造方法
EP1947190B1 (en) 2005-10-18 2017-11-29 Ajinomoto Co., Inc. Process for production of succinic acid
EP2011861A1 (en) 2006-04-24 2009-01-07 Ajinomoto Co., Inc. Bacterium capable of producing purine substance, and process for production of purine substance
ES2401607T3 (es) 2006-04-24 2013-04-23 Ajinomoto Co., Inc. Bacteria que puede producir una sustancia de purina y procedimiento para producir una sustancia de purina
EP2021458A1 (en) 2006-05-23 2009-02-11 Ajinomoto Co., Inc. A method for producing an l-amino acid using a bacterium of the enterobacteriaceae family
EP2066799B1 (en) 2006-09-28 2013-12-11 Ajinomoto Co., Inc. Method for producing 4-hydroxy-l-isoleucine
KR100822041B1 (ko) 2006-12-21 2008-04-15 씨제이제일제당 (주) 몰리브덴 보조인자 생합성 효소 에이 코딩 유전자의 발현이강화된 코리네박테리움 속 미생물 및 이를 이용한엘-라이신 생산방법
KR100882418B1 (ko) 2007-01-15 2009-02-05 씨제이제일제당 (주) 이노신을 생산하는 미생물 및 그를 이용한 이노신 제조방법
KR101730837B1 (ko) 2007-01-22 2017-04-27 아지노모토 가부시키가이샤 Ｌ-아미노산을 생산하는 미생물 및 ｌ-아미노산의 제조법
JP2010088301A (ja) * 2007-02-01 2010-04-22 Ajinomoto Co Inc Ｌ−アミノ酸の製造法
JP2010110217A (ja) * 2007-02-22 2010-05-20 Ajinomoto Co Inc Ｌ−アミノ酸生産菌及びｌ−アミノ酸の製造法
JP2010130899A (ja) 2007-03-14 2010-06-17 Ajinomoto Co Inc Ｌ−グルタミン酸系アミノ酸生産微生物及びアミノ酸の製造法
JPWO2008133131A1 (ja) 2007-04-16 2010-07-22 味の素株式会社 有機酸の製造方法
CN101688176B (zh) * 2007-04-17 2013-11-06 味之素株式会社 具有羧基的酸性物质的生产方法
US7819976B2 (en) * 2007-08-22 2010-10-26 E. I. Du Pont De Nemours And Company Biomass treatment method
US20090053800A1 (en) * 2007-08-22 2009-02-26 Julie Friend Biomass Treatment Apparatus
US7807419B2 (en) * 2007-08-22 2010-10-05 E. I. Du Pont De Nemours And Company Process for concentrated biomass saccharification
US8445236B2 (en) * 2007-08-22 2013-05-21 Alliance For Sustainable Energy Llc Biomass pretreatment
JP2010263790A (ja) * 2007-09-04 2010-11-25 Ajinomoto Co Inc アミノ酸生産微生物及びアミノ酸の製造法
RU2396336C2 (ru) 2007-09-27 2010-08-10 Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО АГРИ) СПОСОБ ПОЛУЧЕНИЯ АМИНОКИСЛОТ С ИСПОЛЬЗОВАНИЕМ БАКТЕРИИ, ПРИНАДЛЕЖАЩЕЙ К РОДУ Escherichia
JP5644108B2 (ja) 2007-12-06 2014-12-24 味の素株式会社 有機酸の製造方法
JP2011067095A (ja) 2008-01-10 2011-04-07 Ajinomoto Co Inc 発酵法による目的物質の製造法
JP5526785B2 (ja) 2008-01-23 2014-06-18 味の素株式会社 Ｌ−アミノ酸の製造法
WO2009154280A1 (ja) * 2008-06-19 2009-12-23 味の素株式会社 過食防止剤
WO2010027022A1 (ja) 2008-09-05 2010-03-11 味の素株式会社 Ｌ－アミノ酸生産菌及びｌ－アミノ酸の製造法
BRPI0918299B1 (pt) 2008-09-08 2018-08-14 Ajinomoto Co., Inc. Método para produzir um l-aminoácido
JP2012029565A (ja) 2008-11-27 2012-02-16 Ajinomoto Co Inc Ｌ−アミノ酸の製造法
CN102471790B (zh) 2009-07-29 2014-10-29 味之素株式会社 产生l-氨基酸的方法
JP5636648B2 (ja) 2009-08-10 2014-12-10 味の素株式会社 ５’−グアニル酸の製造法
JP2012223091A (ja) 2009-08-25 2012-11-15 Ajinomoto Co Inc Ｌ−アミノ酸の製造法
JP2012223092A (ja) 2009-08-28 2012-11-15 Ajinomoto Co Inc Ｌ−アミノ酸の製造法
JP2013013329A (ja) 2009-11-06 2013-01-24 Ajinomoto Co Inc Ｌ−アミノ酸の製造法
JP2013074795A (ja) 2010-02-08 2013-04-25 Ajinomoto Co Inc 変異型ｒｐｓＡ遺伝子及びＬ−アミノ酸の製造法
KR101226384B1 (ko) * 2010-03-05 2013-01-25 씨제이제일제당 (주) 개량된 프로모터 및 이를 이용한 ｌ-라이신의 생산 방법
US8906235B2 (en) 2010-04-28 2014-12-09 E I Du Pont De Nemours And Company Process for liquid/solid separation of lignocellulosic biomass hydrolysate fermentation broth
US8721794B2 (en) 2010-04-28 2014-05-13 E I Du Pont De Nemours And Company Production of high solids syrup from lignocellulosic biomass hydrolysate fermentation broth
RU2501858C2 (ru) 2010-07-21 2013-12-20 Закрытое акционерное общество "Научно-исследовательский институт "Аджиномото-Генетика" (ЗАО АГРИ) СПОСОБ ПОЛУЧЕНИЯ L-АМИНОКИСЛОТЫ С ИСПОЛЬЗОВАНИЕМ БАКТЕРИИ СЕМЕЙСТВА Enterobacteriaceae
WO2012033112A1 (ja) 2010-09-08 2012-03-15 グリーンフェノール・高機能フェノール樹脂製造技術研究組合 コリネ型細菌形質転換体及びそれを用いるフェノールの製造方法
BR112013006031A2 (pt) 2010-09-14 2016-06-07 Ajinomoto Kk bactéria,e, método para produzir um aminoácido contendo enxofre, uma substância relacionada ao mesmo, ou uma mnistura dos mesmos.
WO2012063862A1 (ja) 2010-11-10 2012-05-18 グリーンフェノール・高機能フェノール樹脂製造技術研究組合 コリネ型細菌形質転換体及びそれを用いるフェノールの製造方法
JP2014036576A (ja) 2010-12-10 2014-02-27 Ajinomoto Co Inc Ｌ−アミノ酸の製造法
JP2014087259A (ja) 2011-02-22 2014-05-15 Ajinomoto Co Inc Ｌ−システイン生産菌及びｌ−システインの製造法
JP6032198B2 (ja) 2011-03-18 2016-11-24 三菱化学株式会社 ポリマーの製造方法、有機酸の製造方法及び有機酸生産菌
CN104160024A (zh) 2011-04-01 2014-11-19 味之素株式会社 用于生产l-半胱氨酸的方法
DE102011006716A1 (de) 2011-04-04 2012-10-04 Evonik Degussa Gmbh Mikroorganismus und Verfahren zur fermentativen Herstellung einer organisch-chemischen Verbindung
JP2014131487A (ja) 2011-04-18 2014-07-17 Ajinomoto Co Inc Ｌ−システインの製造法
RU2496867C2 (ru) 2011-04-25 2013-10-27 Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО "АГРИ") Способ получения l-аминокислоты семейства глутамата с использованием коринеформной бактерии
CN103946372B (zh) 2011-11-02 2016-06-08 味之素株式会社 用于分泌产生蛋白质的方法
MY173771A (en) 2011-11-11 2020-02-20 Ajinomoto Kk A method for producing a target substance by fermentation
RU2012129311A (ru) 2012-07-11 2014-01-20 Закрытое акционерное общество " Научно-исследовательский институт Аджиномото-Генетика" (ЗАО "АГРИ") Днк, кодирующая дипептид-синтезирующий фермер (варианты), бактерия рода escherichia и способ получения дипептидов с ее использованием
RU2550269C2 (ru) 2012-08-17 2015-05-10 Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО "АГРИ") СПОСОБ ПОЛУЧЕНИЯ L-АРГИНИНА С ИСПОЛЬЗОВАНИЕМ БАКТЕРИИ СЕМЕЙСТВА Enterobacteriaceae, СОДЕРЖАЩЕЙ N-АЦЕТИЛОРНИТИНДЕАЦЕТИЛАЗУ С НАРУШЕННОЙ АКТИВНОСТЬЮ
EP2762571A1 (de) 2013-01-30 2014-08-06 Evonik Industries AG Mikroorganismus und Verfahren zur fermentativen Herstellung von Aminosäuren
ES2673582T3 (es) 2013-02-08 2018-06-22 Ningxia Eppen Biotech Co. Ltd Método de generación de L-lisina por medio de bacterias fermentadoras que poseen un gen de aconitasa y/o un elemento regulador modificado
US20140273105A1 (en) 2013-03-12 2014-09-18 E I Du Pont De Nemours And Company Gradient pretreatment of lignocellulosic biomass
WO2014160262A1 (en) 2013-03-14 2014-10-02 Abengoa Bioenergy New Technologies, Llc Methods for converting cellulosic waste to bioproducts
RU2013118637A (ru) 2013-04-23 2014-10-27 Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО "АГРИ") СПОСОБ ПОЛУЧЕНИЯ L-АМИНОКИСЛОТ С ИСПОЛЬЗОВАНИЕМ БАКТЕРИИ СЕМЕЙСТВА ENTEROBACTERIACEAE, В КОТОРОЙ РАЗРЕГУЛИРОВАН ГЕН yjjK
RU2013119826A (ru) 2013-04-29 2014-11-10 Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО "АГРИ") Коринеформная бактерия и способ получения гетерологичных гибридных белков
PE20150681A1 (es) 2013-05-13 2015-05-15 Ajinomoto Kk Metodo para producir l-aminoacidos
SG11201502478YA (en) * 2013-05-17 2015-04-29 Xyleco Inc Processing biomass
JP2016165225A (ja) 2013-07-09 2016-09-15 味の素株式会社 有用物質の製造方法
RU2013140115A (ru) 2013-08-30 2015-03-10 Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО "АГРИ") СПОСОБ ПОЛУЧЕНИЯ L-АМИНОКИСЛОТ С ИСПОЛЬЗОВАНИЕМ БАКТЕРИИ СЕМЕЙСТВА Enterobacteriaceae, В КОТОРОЙ НАРУШЕНА ЭКСПРЕССИЯ КЛАСТЕРА ГЕНОВ znuACB
JP2016192903A (ja) 2013-09-17 2016-11-17 味の素株式会社 海藻由来バイオマスからのｌ−アミノ酸の製造方法
WO2015050234A1 (ja) 2013-10-02 2015-04-09 味の素株式会社 アンモニア制御装置およびアンモニア制御方法
EP3054005B1 (en) 2013-10-02 2019-11-20 Ajinomoto Co., Inc. Heparosan-producing bacterium and heparosan manufacturing method
RU2013144250A (ru) 2013-10-02 2015-04-10 Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО "АГРИ") СПОСОБ ПОЛУЧЕНИЯ L-АМИНОКИСЛОТ С ИСПОЛЬЗОВАНИЕМ БАКТЕРИИ СЕМЕЙСТВА Enterobacteriaceae, В КОТОРОЙ ОСЛАБЛЕНА ЭКСПРЕССИЯ ГЕНА, КОДИРУЮЩЕГО ФОСФАТНЫЙ ТРАНСПОРТЕР
ES2694011T3 (es) 2013-10-21 2018-12-17 Ajinomoto Co., Inc. Método para producir L-aminoácido
WO2015060391A1 (ja) 2013-10-23 2015-04-30 味の素株式会社 目的物質の製造法
US10227623B2 (en) 2013-11-24 2019-03-12 E I Du Pont De Nemours And Company High force and high stress destructuring of cellulosic biomass
EP3101130B1 (en) 2014-01-31 2020-05-06 Ajinomoto Co., Inc. Mutant glutamate-cysteine ligase and method for manufacturing gamma-glutamyl-valyl-glycine
WO2016007350A1 (en) 2014-07-09 2016-01-14 Danisco Us Inc. Preconditioning of lignocellulosic biomass
US20170327850A1 (en) * 2014-10-30 2017-11-16 Board Of Regents, The University Of Texas System Engineered fungi for itaconic acid production
CN104513830B (zh) * 2015-01-27 2017-08-11 华东理工大学 一种适用于氧化葡萄糖酸杆菌的基因表达载体及其应用
CA2985279A1 (en) 2015-05-19 2016-11-24 Lucite International Uk Limited Process for the biological production of methacrylic acid and derivatives thereof
RU2015120052A (ru) 2015-05-28 2016-12-20 Аджиномото Ко., Инк. Способ получения L-аминокислоты с использованием бактерии семейства Enterobacteriaceae, в которой ослаблена экспрессия гена gshA
EP3368695A2 (en) 2015-10-27 2018-09-05 Ajinomoto Co., Inc. Method for producing aldehyde
JP6623690B2 (ja) 2015-10-30 2019-12-25 味の素株式会社 グルタミン酸系ｌ−アミノ酸の製造法
JP7107225B2 (ja) 2016-01-12 2022-07-27 味の素株式会社 ベンズアルデヒドの製造方法
WO2018074578A1 (ja) 2016-10-21 2018-04-26 味の素株式会社 タンパク質の分泌生産法
EP3532626B1 (en) 2016-10-26 2023-08-30 Ajinomoto Co., Inc. Method for producing objective substance
CN109937257B (zh) 2016-10-26 2023-06-30 味之素株式会社 生产目标物质的方法
GB201619827D0 (en) 2016-11-23 2017-01-04 Lucite Int Uk Ltd Process for the production of methyl methacrylate
KR20200056437A (ko) 2017-09-25 2020-05-22 아지노모토 가부시키가이샤 단백질의 제조법 및 2당의 제조법
WO2019078095A1 (en) 2017-10-16 2019-04-25 Ajinomoto Co., Inc. PROCESS FOR PRODUCTION OF PROTEIN HAVING ALPHA-HYDROXYLANTIC PEPTIDYLGLYCIN MONOOXYGENASE ACTIVITY
US11680279B2 (en) 2017-11-29 2023-06-20 Ajinomoto Co., Inc. Method for producing objective substance
WO2019130723A1 (en) 2017-12-26 2019-07-04 Ajinomoto Co., Inc. Method of producing glycine by fermentation
BR112020016770A2 (pt) 2018-02-20 2020-12-15 Ajinomoto Co., Inc. Método para induzir silenciamento de rna e para produzir uma composição para induzir silenciamento de rna em um organismo-alvo, e, composição para induzir silenciamento de rna em um organismo-alvo
JP7124338B2 (ja) 2018-02-27 2022-08-24 味の素株式会社 変異型グルタチオン合成酵素、及び、γ－グルタミルバリルグリシンの製造法
CN112384629B (zh) 2018-07-11 2024-05-10 味之素株式会社 使用肠杆菌科细菌对醇和胺进行酶促磺酰化的方法
WO2020027251A1 (en) 2018-08-03 2020-02-06 Ajinomoto Co., Inc. Method for producing objective substance
EP3856918A1 (en) 2018-09-28 2021-08-04 Ajinomoto Co., Inc. Method for producing l-methionine using a bacterium
WO2020071538A1 (en) 2018-10-05 2020-04-09 Ajinomoto Co., Inc. Method for producing target substance by bacterial fermentation
JP7375767B2 (ja) 2018-10-25 2023-11-08 味の素株式会社 タンパク質の分泌生産法
KR102075160B1 (ko) 2018-12-13 2020-02-10 대상 주식회사 L-글루탐산 생산능이 향상된 변이 균주 및 이를 이용한 l-글루탐산의 제조 방법
BR112021011882A2 (pt) 2018-12-27 2021-09-08 Ajinomoto Co., Inc. Método para produzir um l-aminoácido básico
BR112021014194A2 (pt) 2019-02-22 2021-12-28 Ajinomoto Kk Método para a produção de um l-aminoácido
JP2022526181A (ja) 2019-04-05 2022-05-23 味の素株式会社 Ｌ－アミノ酸の製造方法
WO2021060438A1 (en) 2019-09-25 2021-04-01 Ajinomoto Co., Inc. Method for producing l-amino acids by bacterial fermentation
EP4034668B1 (en) 2019-09-25 2024-04-17 Ajinomoto Co., Inc. Method for producing 2-methyl-butyric acid by bacterial fermentation
EP4053287A4 (en) 2019-10-28 2023-11-01 Ajinomoto Co., Inc. METHOD FOR PRODUCING BENZALDEHYDE
CN110951662B (zh) * 2019-12-26 2024-03-12 新疆梅花氨基酸有限责任公司 一种高产赖氨酸的棒状细菌及其构建方法与应用
KR102269639B1 (ko) 2020-02-12 2021-06-25 대상 주식회사 L-글루탐산 생산능이 향상된 코리네박테리움 글루타미쿰 변이주 및 이를 이용한 l-글루탐산의 생산 방법
CN111334535B (zh) * 2020-03-26 2021-11-30 廊坊梅花生物技术开发有限公司 生产l-氨基酸的重组菌株及其应用
CN113201535B (zh) * 2020-07-20 2022-02-08 中国科学院天津工业生物技术研究所 谷氨酸脱氢酶基因启动子的突变体及其应用
EP4223129A1 (en) 2020-09-29 2023-08-09 Ajinomoto Co., Inc. Mutant transglutaminase
JPWO2022092018A1 (pt) 2020-10-28 2022-05-05
CN112695036B (zh) * 2021-03-23 2021-07-06 中国科学院天津工业生物技术研究所 一种天冬氨酸激酶基因表达调控序列及其应用
CN117157396A (zh) 2021-04-16 2023-12-01 因比奥斯公司 唾液酸化的二糖和/或寡糖的细胞生产
AU2022258873A1 (en) 2021-04-16 2023-11-30 Inbiose N.V. Fermentative production
KR102377745B1 (ko) * 2021-05-12 2022-03-23 씨제이제일제당 주식회사 신규 프로모터 및 이의 용도
CN113308426B (zh) * 2021-05-27 2022-10-18 齐鲁工业大学 一种改造tk基因5′端序列的重组棒状杆菌及其应用
WO2023282315A1 (ja) 2021-07-07 2023-01-12 味の素株式会社 非天然アミノ酸含有タンパク質の分泌生産法
WO2023063314A1 (ja) 2021-10-11 2023-04-20 味の素株式会社 異種Ｔａｔ系タンパク質を発現するよう改変された細菌
GB2621337A (en) 2022-08-08 2024-02-14 Mitsubishi Chemical Uk Ltd Process for the biological production of methacrylic acid and derivatives thereof
US20240117393A1 (en) 2022-09-30 2024-04-11 Ajinomoto Co., Inc. Method for producing l-amino acid

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
LU81207A1 (fr) 1979-04-30 1980-12-16 Arbed Procede d'affinage d'un bain de metal contenant des matieres refroidissantes solides
JPS61104790A (ja) 1984-10-29 1986-05-23 Showa Denko Kk Ｌ−トリプトフアンの生合成に関与する遺伝情報を有する新規組換え体ｄｎａ
JP2520895B2 (ja) * 1987-03-04 1996-07-31 旭化成工業株式会社 Ｌ―グルタミン酸の製造方法
JP2708168B2 (ja) 1988-02-23 1998-02-04 昭和電工株式会社 微生物の改良
JPH06502548A (ja) * 1991-07-30 1994-03-24 オルサン 特にコリネバクテリア中で用いることのできる蛋白質の発現および分泌系
CN1272437C (zh) 1994-06-14 2006-08-30 味之素株式会社 α－酮戊二酸脱氢酶基因以及赖氨酸的生产方法
DK0934406T3 (da) 1996-08-23 2009-01-26 Peter Ruhdal Jensen Syntetiske promotor biblioteker til udvalgte organismer og promotorer fra sådanne biblioteker
ES2335828T3 (es) 1998-09-25 2010-04-05 Ajinomoto Co., Inc. Bacterias corineformes para producir l-glu.
US6255086B1 (en) 1999-02-01 2001-07-03 Ajinomoto Co., Inc. Carbamoyl-phosphate synthetase gene of coryneform bacteria and method for producing L-arginine
US7160705B2 (en) 2000-04-28 2007-01-09 Ajinomoto Co., Inc. Arginine repressor deficient strain of coryneform bacterium and method for producing L-arginine

Also Published As

Publication number Publication date
EP1033407A4 (en) 2004-08-18
HU224975B1 (en) 2006-04-28
TW200504214A (en) 2005-02-01
TW200504215A (en) 2005-02-01
TWI247806B (en) 2006-01-21
DE69941594D1 (de) 2009-12-10
US7608437B2 (en) 2009-10-27
CN1289368A (zh) 2001-03-28
SK7702000A3 (en) 2000-10-09
KR20010032426A (ko) 2001-04-16
TWI247808B (en) 2006-01-21
US20040002143A1 (en) 2004-01-01
PE20001111A1 (es) 2000-10-31
RU2214456C2 (ru) 2003-10-20
MY130756A (en) 2007-07-31
CN1170938C (zh) 2004-10-13
ES2335828T3 (es) 2010-04-05
TWI247807B (en) 2006-01-21
KR100630604B1 (ko) 2006-10-04
ATE447039T1 (de) 2009-11-15
ID25513A (id) 2000-10-05
EP1033407B1 (en) 2009-10-28
WO2000018935A1 (fr) 2000-04-06
EP1033407A1 (en) 2000-09-06
BRPI9909409B1 (pt) 2016-03-22
US6962805B2 (en) 2005-11-08
TW200504213A (en) 2005-02-01
US20060003424A1 (en) 2006-01-05
HU225541B1 (en) 2007-03-28
HUP0100045A2 (hu) 2001-05-28
HUP0100045A3 (en) 2003-01-28
TWI247805B (en) 2006-01-21
BR9917880B1 (pt) 2014-02-18

Similar Documents

Publication Publication Date Title
BR9909409A (pt) Processo para produzir bactérias corineformes tendo uma melhorada produtividade de aminoácido ou ácido nucleico, genes sintetizando ácido glutâmico, e arginina sintetase, bactérias corineformes produzindo ácido glutâmico, e produzindo arginina e, processos para produzir um aminoácido ou ácido nucleico por fermentação, e para produzir ácido l-glutâmico por fermentação.
Wu et al. Metabolic engineering of Escherichia coli for high-yield uridine production
US4954441A (en) Process for producing L-lysine
EP0143195B1 (en) Recombinant dna having a phosphoenol pyruvate carboxylase gene inserted therein, bacteria carrying said recombinant dna and a process for producing amino acids using said bacteria
US4980285A (en) Method for producing L-amino acids
JPH06102028B2 (ja) アミノ酸の製造法
CN110418843A (zh) 新型l-色氨酸输出蛋白及使用其生产l-色氨酸的方法
KR100815041B1 (ko) 아미노산 생산의 대사 공학
CN101960005A (zh) 5＇-鸟苷酸的生产方法
US5017482A (en) Process for producing L-arginine
EP2102347A1 (en) Corynebacterium glutamicum variety producing l-arginine and method for fabricating the same
CN105143440B (zh) 具有l-色氨酸生产力的微生物以及使用所述微生物生产l-色氨酸的方法
AU2001274537A1 (en) Novel glucose-6-phosphate dehydrogenase
WO2014027702A1 (en) Method for producing l-arginine using bacterium of the family enterobacteriaceae having n-acetylornithine deacetylase with downregulated activity
CN105980544A (zh) 生产l-氨基酸的微生物及使用所述微生物生产l-氨基酸的方法
KR900004424B1 (ko) 아미노산의 제조방법
WO2003023044A3 (en) Process for the production of l-amino acids using coryneform bacteria
EP0183006B1 (en) A recombinant dna-molecule, coryneform bacteria carrying recombinant dna and process for producing an aromatic amino acid by using the same
CA1283070C (en) Process for production of l-phenylalanine by fermentation
JPS6034197A (ja) チロシンの製造法
KR20020033750A (ko) Ｌ-리신 생산용 돌연변이 박테리아 균주
CENTER Technology to Boost Production Yields
JPS6265691A (ja) 芳香族アミノ酸の製造法
JPS62143682A (ja) 発酵法によるｌ―チロシン又はｌ―フェニルアラニンの製造法

Legal Events

Date Code Title Description
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B09Y Publication of grant cancelled [chapter 9.1.2 patent gazette]

Free format text: REFERENTE A RPI 2195 DE 29/01/2013.

B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B11D Dismissal acc. art. 38, par 2 of ipl - failure to pay fee after grant in time
B11N Dismissal: publication cancelled [chapter 11.14 patent gazette]

Free format text: PUBLICACAO ANULADA REFERENTE RPI/2226 DE 03/09/2013,POR TER SIDO INDEVIDA.

B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 22/03/2016, OBSERVADAS AS CONDICOES LEGAIS.