HUP0100045A2 - Eljárás aminosav-termelő baktériumtörzsek előállítására és az aminosavaknak az előállított aminosav-termelő baktériumtörzsekből fermentálással történő előállítására - Google Patents

Eljárás aminosav-termelő baktériumtörzsek előállítására és az aminosavaknak az előállított aminosav-termelő baktériumtörzsekből fermentálással történő előállítására

Info

Publication number
HUP0100045A2
HUP0100045A2 HU0100045A HUP0100045A HUP0100045A2 HU P0100045 A2 HUP0100045 A2 HU P0100045A2 HU 0100045 A HU0100045 A HU 0100045A HU P0100045 A HUP0100045 A HU P0100045A HU P0100045 A2 HUP0100045 A2 HU P0100045A2
Authority
HU
Hungary
Prior art keywords
amino acid
producing
nucleic acid
producing bacterium
coryneform
Prior art date
Application number
HU0100045A
Other languages
English (en)
Inventor
Yoko Asakura
Hisao Ito
Sohei Kanno
Eiichiro Kimura
Osamu Kurahashi
Kazuhiko Matsui
Tsuyoshi Nakamatsu
Jun Nakamura
Tsuyoshi Ohsumi
Mikiko Suga
Original Assignee
Ajinomoto Co., Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26549879&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HUP0100045(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Ajinomoto Co., Inc. filed Critical Ajinomoto Co., Inc.
Publication of HUP0100045A2 publication Critical patent/HUP0100045A2/hu
Publication of HUP0100045A3 publication Critical patent/HUP0100045A3/hu
Publication of HU224975B1 publication Critical patent/HU224975B1/hu

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/67—General methods for enhancing the expression
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/14—Glutamic acid; Glutamine

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  • Genetics & Genomics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Plant Pathology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

A találmány tárgya fokozott aminosav- vagy nukleinsavtermelő képességűkorineform baktérium előállítására szolgáló eljárás, amelynek soránmutációkat visznek be a korineform baktérium kromoszómájánelhelyezkedő aminosav- vagy nukleinsav-bioszintetizáló génekpromóterszekvenciájába és ezzel hasonlóvá teszik egy konszenzusszekvenciához, vagy génrekombinációval megváltoztatják a korineformbaktérium kromoszómáján elhelyezkedő aminosav- vagy nukleinsav-bioszintetizáló gének promóterszekvenciáját, és ezzel hasonlóvá teszikegy konszenzus szekvenciához, így mutáns aminosav- vagynukleinsavtermelő korineform mikroorganizmusokat kapnak, amelyekettenyésztenek és kiszelektálják közülük a vizsgált aminosavat vagynukleinsavat nagy mennyiségben termelni képes mutánst. A találmánytárgyát képezik továbbá az aminosavak fokozott szintetizálásáraalkalmas gének és korineform baktériumok, továbbá eljárások aminosav-vagy nukleinsavtermelésre. A találmány szerinti eljárással, plazmidalkalmazása nélkül, rekombinációval vagy mutációval olyan mutánsállítható elő, amely megfelelően fokozza vagy irányítja egy adott génexpresszióját, és amely nagy mennyiségben képes aminosavakat termelni. Ó
HU0100045A 1998-09-25 1999-09-22 Process for producing l-amino acids by fermentation and amino acid-producing bacterium strains HU224975B1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP27178798 1998-09-25
JP27178698 1998-09-25
PCT/JP1999/005175 WO2000018935A1 (fr) 1998-09-25 1999-09-22 Procede de construction d'une bacterie produisant des acides amines, et procede de production d'acides amines par une technique de fermentation utilisant ladite bacterie

Publications (3)

Publication Number Publication Date
HUP0100045A2 true HUP0100045A2 (hu) 2001-05-28
HUP0100045A3 HUP0100045A3 (en) 2003-01-28
HU224975B1 HU224975B1 (en) 2006-04-28

Family

ID=26549879

Family Applications (2)

Application Number Title Priority Date Filing Date
HU0100045D HU225541B1 (en) 1998-09-25 1999-09-22 Process for producing l-amino acids by fermentation and amino acid-producing bacterium strains
HU0100045A HU224975B1 (en) 1998-09-25 1999-09-22 Process for producing l-amino acids by fermentation and amino acid-producing bacterium strains

Family Applications Before (1)

Application Number Title Priority Date Filing Date
HU0100045D HU225541B1 (en) 1998-09-25 1999-09-22 Process for producing l-amino acids by fermentation and amino acid-producing bacterium strains

Country Status (16)

Country Link
US (2) US6962805B2 (hu)
EP (1) EP1033407B1 (hu)
KR (1) KR100630604B1 (hu)
CN (1) CN1170938C (hu)
AT (1) ATE447039T1 (hu)
BR (2) BR9917880B1 (hu)
DE (1) DE69941594D1 (hu)
ES (1) ES2335828T3 (hu)
HU (2) HU225541B1 (hu)
ID (1) ID25513A (hu)
MY (1) MY130756A (hu)
PE (1) PE20001111A1 (hu)
RU (1) RU2214456C2 (hu)
SK (1) SK7702000A3 (hu)
TW (4) TWI247807B (hu)
WO (1) WO2000018935A1 (hu)

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* Cited by examiner, † Cited by third party
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