ZA200604580B - Heterocyclic inhibitors of Mek and methods of use thereof - Google Patents
Heterocyclic inhibitors of Mek and methods of use thereofInfo
- Publication number
- ZA200604580B ZA200604580B ZA200604580A ZA200604580A ZA200604580B ZA 200604580 B ZA200604580 B ZA 200604580B ZA 200604580 A ZA200604580 A ZA 200604580A ZA 200604580 A ZA200604580 A ZA 200604580A ZA 200604580 B ZA200604580 B ZA 200604580B
- Authority
- ZA
- South Africa
- Prior art keywords
- compounds
- methods
- mek
- heterocyclic inhibitors
- mammals
- Prior art date
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- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/44—Iso-indoles; Hydrogenated iso-indoles
- C07D209/46—Iso-indoles; Hydrogenated iso-indoles with an oxygen atom in position 1
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- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
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