JPS55167221A - Anticancer drug - Google Patents
Anticancer drugInfo
- Publication number
- JPS55167221A JPS55167221A JP7493879A JP7493879A JPS55167221A JP S55167221 A JPS55167221 A JP S55167221A JP 7493879 A JP7493879 A JP 7493879A JP 7493879 A JP7493879 A JP 7493879A JP S55167221 A JPS55167221 A JP S55167221A
- Authority
- JP
- Japan
- Prior art keywords
- formula
- anticancer drug
- activity
- organs
- cancers
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Abstract
PURPOSE: An anticancer drug having activity against almost all cancers, comprising maleic hydragide as an active constituent.
CONSTITUTION: An anticancer drug comprising as an active constituent maleic hydrazide (1,2-dihydropyridazine-3,6-dione) of formula I which is obtained as a ketoenol tautomer with 3,6-dihydroxypyridazine of formula II by reacting maleic anhydride with hydrazine. Although known to have a growth-regulating activity on the juvenile cells of plants, the compound of formula I was found to have not only low toxicity snd little side effects but also the anticancer activity or human bodies by being administered orally or parenterally particularly with the efficacy of 57% against the cancers in digestive organs, genital organs, respiratory organs, etc.
COPYRIGHT: (C)1980,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP7493879A JPS55167221A (en) | 1979-06-13 | 1979-06-13 | Anticancer drug |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP7493879A JPS55167221A (en) | 1979-06-13 | 1979-06-13 | Anticancer drug |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS55167221A true JPS55167221A (en) | 1980-12-26 |
Family
ID=13561782
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP7493879A Pending JPS55167221A (en) | 1979-06-13 | 1979-06-13 | Anticancer drug |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS55167221A (en) |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0665223A1 (en) * | 1994-01-28 | 1995-08-02 | Takeda Chemical Industries, Ltd. | Antitumor agent, novel 3(2H)-pyridazinone derivatives and their preparation |
JP2011121984A (en) * | 2003-11-19 | 2011-06-23 | Array Biopharma Inc | Bicyclic inhibitor of mek and method of use thereof |
KR101336692B1 (en) * | 2011-12-27 | 2013-12-03 | 경희대학교 산학협력단 | Poly(ethylene oxide)-based block copolymer bearing hydrazide moiety and iron oxide nanoparticle stabilized by the same |
-
1979
- 1979-06-13 JP JP7493879A patent/JPS55167221A/en active Pending
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0665223A1 (en) * | 1994-01-28 | 1995-08-02 | Takeda Chemical Industries, Ltd. | Antitumor agent, novel 3(2H)-pyridazinone derivatives and their preparation |
JP2011121984A (en) * | 2003-11-19 | 2011-06-23 | Array Biopharma Inc | Bicyclic inhibitor of mek and method of use thereof |
KR101336692B1 (en) * | 2011-12-27 | 2013-12-03 | 경희대학교 산학협력단 | Poly(ethylene oxide)-based block copolymer bearing hydrazide moiety and iron oxide nanoparticle stabilized by the same |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ES473451A1 (en) | Imidazole derivatives their synthesis and their pharmaceutical formulations. | |
CA2040982A1 (en) | N-(3-fluoro-2-phosphonylmethoxypropyl) derivatives of purine and pyrimidine heterocyclic bases, their preparation and use | |
FR2363329A1 (en) | 4-Carbamoyl-5-hydroxy-imidazole - used to treat cancer, nephritis and rheumatism | |
JPS55167221A (en) | Anticancer drug | |
IE780981L (en) | 6-(substituted amino)-penam compounds | |
ES482742A1 (en) | Substituted 2-phenylamino-imidazolines-(2), their acid addition salts, medicaments containing them and processes for their preparation. | |
ES455721A1 (en) | Urapidil/furosemide compounds, compositions and use | |
JPS57114512A (en) | Antidia beticagent comprising (3-dimethyl-carbamoxy- phenyl)trimethyl ammonium derivative | |
JPS54151134A (en) | Antitumorigenic agent | |
JPS5536454A (en) | Novel immunosuppressive agent | |
IE43863L (en) | Imidazole derivatives | |
ES471874A1 (en) | Herbicidally active 1,2,4-triazin-5-one derivatives | |
JPS5610114A (en) | Novel analgesic and anti-inflammatory agent | |
JPS5278887A (en) | Synthesis of n-(2-tetrahydrofuryl)-5-fluorouracil | |
JPS5248677A (en) | Preparation of pyrimidine derivatives | |
JPS57165318A (en) | Remedy for asthma | |
JPS5289680A (en) | Preparation of 1-(2-tetrahydrofuryl)-5-flurouracil | |
Osswald et al. | Potentiation of the chemotherapeutic action of Bleomycin by combination with inosine on HRS-Sarcoma | |
JPS5268182A (en) | Preparation of novel triazole derivatives | |
JPS53108987A (en) | Preparation of 1-(2'-tetrahydrofuryl)-5-fluorouracil | |
JPS5325534A (en) | Mandelic acid glucosides and their anti-cancerous preparations | |
JPS5718616A (en) | Remedy for nephropathy | |
JPS525782A (en) | Preparation of 1-phthalazinone | |
JPS57171989A (en) | Aminometyl-secalonic acid and its preparation | |
FR2424270A1 (en) | 4,5-Di:hydro-2-imidazolyl-amino-isoquinoline derivs. - useful as antihypertensives having low toxicity and free from sedative side effects |