YU49221B - Novi derivati eritromicina, postupak za njihovo dobivanje i njihova primena kao lekova - Google Patents

Novi derivati eritromicina, postupak za njihovo dobivanje i njihova primena kao lekova

Info

Publication number
YU49221B
YU49221B YU21695A YU21695A YU49221B YU 49221 B YU49221 B YU 49221B YU 21695 A YU21695 A YU 21695A YU 21695 A YU21695 A YU 21695A YU 49221 B YU49221 B YU 49221B
Authority
YU
Yugoslavia
Prior art keywords
carbon atoms
hydrogen atom
heteroatoms
medicines
procedure
Prior art date
Application number
YU21695A
Other languages
English (en)
Serbo-Croatian (sh)
Other versions
YU21695A (sh
Inventor
Constantin Agouridas
Yannick Benedetti
Jean-Francois Chantot
Alexis Denis
Odile Le Martret
Original Assignee
Roussel-Uclaf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel-Uclaf filed Critical Roussel-Uclaf
Publication of YU21695A publication Critical patent/YU21695A/sh
Publication of YU49221B publication Critical patent/YU49221B/sh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
YU21695A 1994-04-08 1995-04-05 Novi derivati eritromicina, postupak za njihovo dobivanje i njihova primena kao lekova YU49221B (sh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9404154A FR2718450B1 (fr) 1994-04-08 1994-04-08 Nouveaux dérivés de l'érythromycine, leur procédé de préparation et leur application comme médicaments.

Publications (2)

Publication Number Publication Date
YU21695A YU21695A (sh) 1997-12-05
YU49221B true YU49221B (sh) 2004-11-25

Family

ID=9461886

Family Applications (1)

Application Number Title Priority Date Filing Date
YU21695A YU49221B (sh) 1994-04-08 1995-04-05 Novi derivati eritromicina, postupak za njihovo dobivanje i njihova primena kao lekova

Country Status (49)

Country Link
US (2) US5656607A (https=)
EP (1) EP0676409B1 (https=)
JP (1) JP3000023B2 (https=)
KR (1) KR100317148B1 (https=)
CN (1) CN1059445C (https=)
AP (1) AP587A (https=)
AT (1) ATE234853T1 (https=)
AU (1) AU684939B2 (https=)
BG (1) BG61916B1 (https=)
BR (1) BR9506147A (https=)
CA (1) CA2164638C (https=)
CO (1) CO4370097A1 (https=)
CZ (1) CZ296005B6 (https=)
DE (1) DE69529934T2 (https=)
DK (1) DK0676409T3 (https=)
DZ (1) DZ1869A1 (https=)
EE (1) EE04498B1 (https=)
ES (1) ES2189820T3 (https=)
FI (1) FI111264B (https=)
FR (1) FR2718450B1 (https=)
GB (1) GB2288174A (https=)
GE (1) GEP19991836B (https=)
HR (1) HRP950217B1 (https=)
HU (1) HU215396B (https=)
IL (1) IL112954A (https=)
IS (1) IS1865B (https=)
JO (1) JO1850B1 (https=)
LV (1) LV11182B (https=)
MA (1) MA23501A1 (https=)
MD (1) MD663G2 (https=)
MY (1) MY114672A (https=)
NO (1) NO308361B1 (https=)
NZ (1) NZ284498A (https=)
OA (1) OA10200A (https=)
PE (1) PE2896A1 (https=)
PL (1) PL180837B1 (https=)
PT (1) PT676409E (https=)
RO (1) RO115634B1 (https=)
RU (1) RU2141965C1 (https=)
SA (1) SA97170757A (https=)
SI (1) SI0676409T1 (https=)
SK (1) SK284079B6 (https=)
SV (1) SV1995000018A (https=)
TN (1) TNSN95026A1 (https=)
TW (1) TW316908B (https=)
UA (1) UA44705C2 (https=)
WO (1) WO1995027720A1 (https=)
YU (1) YU49221B (https=)
ZA (1) ZA952059B (https=)

Families Citing this family (50)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2732023B1 (fr) * 1995-03-22 1997-04-30 Roussel Uclaf Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
FR2742757B1 (fr) * 1995-12-22 1998-01-30 Roussel Uclaf Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
FR2745289B1 (fr) * 1996-02-28 1998-05-29 Roussel Uclaf Nouveaux derives de l'acide 1(2h) quinoleine carboxylique, leur procede de preparation et leur application a la synthese de produits doues de proprietes antibiotiques
US5750510A (en) * 1997-04-04 1998-05-12 Abbott Laboratories 3-descladinose-2,3-anhydroerythromycin derivatives
AU710532B2 (en) * 1996-05-07 1999-09-23 Abbott Laboratories 3-descladinose-2,3-anhydroerythromycin derivatives
FR2748746B1 (fr) * 1996-05-14 1998-08-14 Hoechst Marion Roussel Inc Nouveau procede d'isomerisation du radical methyle en 10 de derives de l'erythromycine
FR2751656B1 (fr) * 1996-07-24 1998-10-16 Hoechst Marion Roussel Inc Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
DE69733422T2 (de) * 1996-09-04 2006-05-04 Abbott Laboratories, Abbott Park 6-0-substituierte ketoliden mit antibakteriellen wirkung
UA51730C2 (uk) * 1996-09-04 2002-12-16 Ебботт Лабораторіз 6-o-заміщені кетоліди з антибактеріальною активністю, спосіб їх одержання (варіанти), фармацевтична композиція та спосіб регулювання бактеріальної інфекції у ссавців
FR2757168B1 (fr) * 1996-12-12 1999-06-11 Hoechst Marion Roussel Inc Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
FR2760017B1 (fr) * 1997-02-27 1999-04-30 Hoechst Marion Roussel Inc Nouveaux derives de l'erytromycine, leur procede de preparation et leur application comme medicaments
AU4472897A (en) * 1997-03-10 1998-09-29 Taisho Pharmaceutical Co., Ltd. Erythromycin a derivatives
US6140479A (en) * 1997-03-24 2000-10-31 Taisho Pharmaceuticals Co., Ltd. Erythromycin a derivatives
WO1998051696A1 (en) * 1997-05-09 1998-11-19 Pfizer Products Inc. Erythromycin derivatives
US5922683A (en) * 1997-05-29 1999-07-13 Abbott Laboratories Multicyclic erythromycin derivatives
EP0988308A1 (en) * 1997-06-11 2000-03-29 Pfizer Products Inc. 9-oxime erythromycin derivatives
FR2771008B1 (fr) * 1997-11-17 2000-04-28 Hoechst Marion Roussel Inc Utilisation des ketolides pour la preparation de compositions pharmaceutiques destinees a prevenir les complications thrombotiques arterielles liees a l'atherosclerose
AP1060A (en) * 1998-01-02 2002-04-23 Pfizer Prod Inc Novel erythromycin derivatives.
HRP980189B1 (en) * 1998-04-06 2004-04-30 Pliva Pharm & Chem Works Novel 15-membered lactams ketolides
ES2243066T3 (es) * 1998-09-22 2005-11-16 Pfizer Products Inc. Antibioticos de carbamato y carbazato cetolida.
FR2786188B1 (fr) * 1998-11-24 2002-10-31 Hoechst Marion Roussel Inc Nouveaux derives de l'erythromycine, leur procede de preparation et leur applicaion comme medicaments
DE69933897T2 (de) 1998-12-10 2007-03-15 Pfizer Products Inc., Groton Carbamat- und Carbazatketolid-Antibiotika
EP1298138B1 (en) * 1998-12-10 2006-11-02 Pfizer Products Inc. Carbamate and Carbazate Ketolide Antibiotics
EP1749832A3 (en) * 1998-12-10 2008-03-26 Pfizer Products Incorporated Carbamate and carbazate ketolide antibiotics
FR2789392B1 (fr) * 1999-02-04 2001-10-05 Hoechst Marion Roussel Inc Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
US6054435A (en) * 1999-03-19 2000-04-25 Abbott Laboratories 6-O-substituted macrolides having antibacterial activity
ATE340183T1 (de) * 1999-04-16 2006-10-15 Kosan Biosciences Inc Antiinfektiöse makrolidderivate
CA2370743A1 (en) 1999-04-16 2000-10-26 Dennis Hlasta Ketolide antibacterials
US6590083B1 (en) 1999-04-16 2003-07-08 Ortho-Mcneil Pharmaceutical, Inc. Ketolide antibacterials
HUP0201516A3 (en) * 1999-05-24 2003-03-28 Pfizer Prod Inc 13-methyl-erythromycin derivatives, process for their preparation and pharmaceutical compositions containing them
CA2451391A1 (en) 2001-07-03 2003-01-16 Chiron Corporation C12 modified erythromycin macrolides and ketolides having antibacterial activity
US7332304B2 (en) 2002-07-01 2008-02-19 Arkion Life Sciences Llc Process and materials for production of glucosamine and N-acetylglucosamine
EP1638549A4 (en) * 2003-03-10 2011-06-15 Optimer Pharmaceuticals Inc NEW ANTIBACTERIAL AGENTS
CA2523134A1 (en) * 2003-04-25 2004-11-11 Chiron Corporation Pyridyl substituted ketolide antibiotics
US7163924B2 (en) * 2003-04-25 2007-01-16 Chiron Corporation Ketolide derivatives
EP2214484A4 (en) 2007-10-25 2013-01-02 Cempra Pharmaceuticals Inc PROCESS FOR PREPARING ANTIBACTERIAL MAKROLIDE AGENTS
JP5711135B2 (ja) 2008-10-24 2015-04-30 センプラ ファーマシューティカルズ，インコーポレイテッド 胃腸疾患を治療するための方法
US9937194B1 (en) 2009-06-12 2018-04-10 Cempra Pharmaceuticals, Inc. Compounds and methods for treating inflammatory diseases
ES2608285T3 (es) 2009-09-10 2017-04-07 Cempra Pharmaceuticals, Inc. Procedimientos para el tratamiento de paludismo, tuberculosis y enfermedades por MAC
MX361413B (es) 2010-03-22 2018-12-05 Cempra Pharmaceuticals Inc Star Formas cristalinas de un macrólido y usos para las mismas.
CN102917708B (zh) 2010-05-20 2015-11-25 森普拉制药公司 制备大环内酯和酮内酯及其中间体的方法
EP2613630A4 (en) 2010-09-10 2014-01-15 Cempra Pharmaceuticals Inc HYDROGEN BOND FOR THE PREPARATION OF FLUOROCHETOLIDES FOR THE TREATMENT OF DISEASES
NZ700182A (en) 2012-03-27 2017-02-24 Cempra Pharmaceuticals Inc Parenteral formulations for administering macrolide antibiotics
AU2014239959A1 (en) 2013-03-14 2015-10-01 Cempra Pharmaceuticals, Inc. Methods for treating respiratory diseases and formulations therefor
CN105188712A (zh) 2013-03-15 2015-12-23 森普拉制药公司 用于制备大环内酯抗菌剂的收敛方法
JP6437523B2 (ja) 2013-04-04 2018-12-12 プレジデント アンド フェローズ オブ ハーバード カレッジ マクロライドならびにそれらの調製および使用の方法
CN106998685A (zh) * 2014-10-08 2017-08-01 哈佛大学的校长及成员们 14‑元酮内酯及其制备和使用方法
EP3273969A4 (en) 2015-03-25 2018-11-21 President and Fellows of Harvard College Macrolides with modified desosamine sugars and uses thereof
MD1222Z (ro) * 2017-05-31 2018-08-31 ИНСТИТУТ ЭЛЕКТРОННОЙ ИНЖЕНЕРИИ И НАНОТЕХНОЛОГИЙ "D. Ghitu" АНМ Procedeu de tratare a materialului săditor al florilor înainte de plantare
JP7199722B2 (ja) 2019-12-25 2023-01-06 旭精工株式会社 硬貨搬送振分機構及びそれを備えた硬貨識別搬送装置

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3868414A (en) * 1973-01-22 1975-02-25 Merck & Co Inc Tetrahydrofluorene carboxylic acids and related compounds
AT342770B (de) * 1975-04-07 1978-04-25 Thomae Gmbh Dr K Verfahren zur herstellung neuer erythromycinderivate
DE2842759A1 (de) * 1978-09-30 1980-04-10 Merck Patent Gmbh Basische aether, diese enthaltende pharmazeutische zubereitungen und verfahren zu ihrer herstellung
IL99995A (en) * 1990-11-21 1997-11-20 Roussel Uclaf Erythromycin derivatives, their preparation and pharmaceutical compositions containing them
FR2692579B1 (fr) * 1992-06-19 1995-06-02 Roussel Uclaf Nouveaux dérivés de la picromycine, leur procédé de préparation et leur application comme médicaments.
FR2697524B1 (fr) * 1992-11-05 1994-12-23 Roussel Uclaf Nouveaux dérivés de l'érythromycine, leur procédé de préparation et leur application comme médicaments.
US5527780A (en) * 1992-11-05 1996-06-18 Roussel Uclaf Erythromycin derivatives
HRP930014A2 (en) * 1993-01-08 1994-08-31 Pliva Pharm & Chem Works 9-deoxo-9a-aza-11-deoxy-9a-homoeritromycin a 9a, 11-cyclic carbamates
FR2702480B1 (fr) * 1993-03-09 1995-04-28 Roussel Uclaf Nouveaux dérivés de l'érythromycine, leur procédé de préparation et leur application comme médicaments.

Also Published As

Publication number Publication date
PL180837B1 (pl) 2001-04-30
FR2718450A1 (fr) 1995-10-13
EE04498B1 (et) 2005-06-15
MD663F1 (ro) 1997-01-31
SK154695A3 (en) 1996-10-02
RO115634B1 (ro) 2000-04-28
NO308361B1 (no) 2000-09-04
SI0676409T1 (en) 2003-06-30
MD663G2 (ro) 1997-07-31
YU21695A (sh) 1997-12-05
AP9500743A0 (en) 1995-07-31
UA44705C2 (uk) 2002-03-15
GB2288174A (en) 1995-10-11
JPH07278177A (ja) 1995-10-24
IS1865B (is) 2003-05-02
SA97170757A (ar) 2005-12-03
IL112954A0 (en) 1995-06-29
GB9506856D0 (en) 1995-05-24
HRP950217B1 (en) 2004-06-30
NO954942L (no) 1996-02-07
EP0676409B1 (fr) 2003-03-19
JO1850B1 (en) 1995-12-27
EP0676409A1 (fr) 1995-10-11
KR100317148B1 (ko) 2002-06-22
MY114672A (en) 2002-12-31
LV11182A (lv) 1996-04-20
CO4370097A1 (es) 1996-10-07
FI955913A0 (fi) 1995-12-08
IL112954A (en) 2000-07-16
TW316908B (https=) 1997-10-01
BG100150A (bg) 1996-06-28
FR2718450B1 (fr) 1997-01-10
CA2164638A1 (fr) 1995-10-19
IS4309A (is) 1995-11-17
CZ296005B6 (cs) 2005-12-14
AU684939B2 (en) 1998-01-08
PE2896A1 (es) 1996-02-12
US5760233A (en) 1998-06-02
NZ284498A (en) 1997-07-27
CN1059445C (zh) 2000-12-13
WO1995027720A1 (fr) 1995-10-19
ZA952059B (en) 1996-03-13
NO954942D0 (no) 1995-12-06
PL311871A1 (en) 1996-03-18
EE9500080A (et) 1996-12-16
DZ1869A1 (fr) 2002-02-17
GEP19991836B (en) 1999-11-05
FI955913A7 (fi) 1995-12-08
HU9503505D0 (en) 1996-02-28
JP3000023B2 (ja) 2000-01-17
RU2141965C1 (ru) 1999-11-27
AU2310795A (en) 1995-10-30
CZ322395A3 (en) 1996-08-14
DE69529934T2 (de) 2003-09-04
US5656607A (en) 1997-08-12
BR9506147A (pt) 1996-04-16
LV11182B (en) 1997-04-20
MA23501A1 (fr) 1995-12-31
CN1126997A (zh) 1996-07-17
ES2189820T3 (es) 2003-07-16
TNSN95026A1 (fr) 1996-02-06
PT676409E (pt) 2003-08-29
OA10200A (fr) 1996-12-18
HU215396B (hu) 1998-12-28
DK0676409T3 (da) 2003-06-23
HUT73772A (en) 1996-09-30
SV1995000018A (es) 1997-10-24
AP587A (en) 1997-04-29
HRP950217A2 (en) 1997-08-31
FI111264B (fi) 2003-06-30
SK284079B6 (sk) 2004-09-08
DE69529934D1 (de) 2003-04-24
CA2164638C (fr) 2003-12-30
BG61916B1 (bg) 1998-09-30
ATE234853T1 (de) 2003-04-15

Similar Documents

Publication Publication Date Title
YU49221B (sh) Novi derivati eritromicina, postupak za njihovo dobivanje i njihova primena kao lekova
NZ505968A (en) Sulfonylamino derivatives which inhibit matrix- degrading metallproteinases
ES2089585T3 (es) Derivados de vitamina d sustituidos con metilo en posicion 20.
HUP9802034A2 (hu) Az endotelin aktívitását módosító tienil-, furil-, pirrolil- és bifenilil-szulfonamidok, ezek származékai és alkalmazásuk
KR890011601A (ko) (사이클로알킬아미노)메틸렌비스(포스폰산)및 활성성분으로서 이를 함유한 의약
CZ15795A3 (en) Derivatives of hydroxamic acid, process of their preparation, their use for preparing pharmaceutical preparations and pharmaceutical compositions containing thereof
UA48937C2 (uk) Імідазолідини, заміщені гетероциклом, спосіб їх одержання і фармацевтична композиція, що їх містить
ATE103812T1 (de) Zusammensetzung zur behandlung von ischaemischen stoerungen in organen.
KR890014480A (ko) 2-피리딜아세트산 유도체, 이의 제조방법 및 이를 함유하는 약제학적 조성물
KR900016178A (ko) 2-치환 n,n'-디트리메톡시벤조일 피페라진, 그의 제조 방법 및 그를 함유하는 치료 조성물
PH21177A (en) 1,6-naphthyridine derivatives, pharmaceutical compositions containing them and method of use
ATE215934T1 (de) Neue histidinderivate, verfahren zu ihrer herstellung und ihre verwendung als mittel gegen freie radikale
FR2616663B1 (fr) Nouveaux tripeptides a structure polycyclique azotee, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
ATE34739T1 (de) Neue 2-pyridin-thiol-derivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate.
AR002259A1 (es) Derivados de 1-oxo-2-(fenilsulfonilamino)pentilpiperidina, su preparacion, compuestos intermedios y composicion que contiene a dichos derivados.
PT76861A (fr) Procede de preparation de nouveaux derives d'oxazinobenzothiazine-6,6-dioxide et de compositions pharmaceutiques les contenant
HRP20000733B1 (hr) NOVI DERIVATI OKTAHIDRO-6,10-DIOKSO-6H-PIRIDAZINO [1,2-a] [1,2]DIAZEPIN-1-KARBOKSILNE KISELINE, POSTUPAK NJIHOVOG DOBIVANJA I UPOTREBA U DOBIVANJU TERAPEUTSKI AKTIVNIH SPOJEVA
DE3578608D1 (de) Substituierte azabicycloheptane, ihre verwendung, pharmazeutische praeparate, welche diese verbindungen enthalten, und verfahren zur herstellung dieser verbindungen.
YU48094B (sh) Derivati fenoksietilamina i postupak za njihovo dobijanje
AU539348B2 (en) 5,6,8,9-tetrahydro-7h-dibenz(d,f)azonine derivatives
KR880013562A (ko) 7-티아프로스타글란딘e₁ 또는 그의 유도체를 함유하는 당뇨병치료 조성물
ES451466A1 (es) Procedimiento para la preparacion de nuevos derivados de 5- tiazol-metanoamina.
DE3166727D1 (en) Derivatives of 2-thiazolyl-oxamic acid substituted in position 4 by a thienyl or furyl radical, their preparation and use as pharmaceutical preparations
AP9901566A0 (en) Novel erythromycin derivatives, method of preparation and application as medicines.
YU47562B (sh) Benzotiazinski derivati i postupak za njihovo dobijanje