EE04498B1 - Erütromütsiini derivaadid, nende valmistamismeetod ja neid sisaldav farmatseutiline kompositsioon - Google Patents

Erütromütsiini derivaadid, nende valmistamismeetod ja neid sisaldav farmatseutiline kompositsioon

Info

Publication number
EE04498B1
EE04498B1 EE9500080A EE9500080A EE04498B1 EE 04498 B1 EE04498 B1 EE 04498B1 EE 9500080 A EE9500080 A EE 9500080A EE 9500080 A EE9500080 A EE 9500080A EE 04498 B1 EE04498 B1 EE 04498B1
Authority
EE
Estonia
Prior art keywords
preparation
pharmaceutical composition
composition containing
erythromycin derivatives
erythromycin
Prior art date
Application number
EE9500080A
Other languages
English (en)
Other versions
EE9500080A (et
Inventor
Agouridas Constantin
Benedetti Yannick
Chantot Jean-Fran�Ois
Denis Alexis
Le Martret Odile
Original Assignee
Roussel Uclaf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf filed Critical Roussel Uclaf
Publication of EE9500080A publication Critical patent/EE9500080A/et
Publication of EE04498B1 publication Critical patent/EE04498B1/et

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
EE9500080A 1994-04-08 1995-04-06 Erütromütsiini derivaadid, nende valmistamismeetod ja neid sisaldav farmatseutiline kompositsioon EE04498B1 (et)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9404154A FR2718450B1 (fr) 1994-04-08 1994-04-08 Nouveaux dérivés de l'érythromycine, leur procédé de préparation et leur application comme médicaments.
PCT/FR1995/000441 WO1995027720A1 (fr) 1994-04-08 1995-04-06 Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments

Publications (2)

Publication Number Publication Date
EE9500080A EE9500080A (et) 1996-12-16
EE04498B1 true EE04498B1 (et) 2005-06-15

Family

ID=9461886

Family Applications (1)

Application Number Title Priority Date Filing Date
EE9500080A EE04498B1 (et) 1994-04-08 1995-04-06 Erütromütsiini derivaadid, nende valmistamismeetod ja neid sisaldav farmatseutiline kompositsioon

Country Status (49)

Country Link
US (2) US5656607A (et)
EP (1) EP0676409B1 (et)
JP (1) JP3000023B2 (et)
KR (1) KR100317148B1 (et)
CN (1) CN1059445C (et)
AP (1) AP587A (et)
AT (1) ATE234853T1 (et)
AU (1) AU684939B2 (et)
BG (1) BG61916B1 (et)
BR (1) BR9506147A (et)
CA (1) CA2164638C (et)
CO (1) CO4370097A1 (et)
CZ (1) CZ296005B6 (et)
DE (1) DE69529934T2 (et)
DK (1) DK0676409T3 (et)
DZ (1) DZ1869A1 (et)
EE (1) EE04498B1 (et)
ES (1) ES2189820T3 (et)
FI (1) FI111264B (et)
FR (1) FR2718450B1 (et)
GB (1) GB2288174A (et)
GE (1) GEP19991836B (et)
HR (1) HRP950217B1 (et)
HU (1) HU215396B (et)
IL (1) IL112954A (et)
IS (1) IS1865B (et)
JO (1) JO1850B1 (et)
LV (1) LV11182B (et)
MA (1) MA23501A1 (et)
MD (1) MD663G2 (et)
MY (1) MY114672A (et)
NO (1) NO308361B1 (et)
NZ (1) NZ284498A (et)
OA (1) OA10200A (et)
PE (1) PE2896A1 (et)
PL (1) PL180837B1 (et)
PT (1) PT676409E (et)
RO (1) RO115634B1 (et)
RU (1) RU2141965C1 (et)
SA (1) SA97170757A (et)
SI (1) SI0676409T1 (et)
SK (1) SK284079B6 (et)
SV (1) SV1995000018A (et)
TN (1) TNSN95026A1 (et)
TW (1) TW316908B (et)
UA (1) UA44705C2 (et)
WO (1) WO1995027720A1 (et)
YU (1) YU49221B (et)
ZA (1) ZA952059B (et)

Families Citing this family (49)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2732023B1 (fr) * 1995-03-22 1997-04-30 Roussel Uclaf Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
FR2742757B1 (fr) 1995-12-22 1998-01-30 Roussel Uclaf Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
FR2745289B1 (fr) * 1996-02-28 1998-05-29 Roussel Uclaf Nouveaux derives de l'acide 1(2h) quinoleine carboxylique, leur procede de preparation et leur application a la synthese de produits doues de proprietes antibiotiques
CZ349698A3 (cs) * 1996-05-07 1999-04-14 Abbott Laboratories 3-deskladinoso-2,3-anhydroerythromycinové deriváty
US5750510A (en) * 1997-04-04 1998-05-12 Abbott Laboratories 3-descladinose-2,3-anhydroerythromycin derivatives
FR2748746B1 (fr) * 1996-05-14 1998-08-14 Hoechst Marion Roussel Inc Nouveau procede d'isomerisation du radical methyle en 10 de derives de l'erythromycine
FR2751656B1 (fr) * 1996-07-24 1998-10-16 Hoechst Marion Roussel Inc Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
UA51730C2 (uk) * 1996-09-04 2002-12-16 Ебботт Лабораторіз 6-o-заміщені кетоліди з антибактеріальною активністю, спосіб їх одержання (варіанти), фармацевтична композиція та спосіб регулювання бактеріальної інфекції у ссавців
PL188173B1 (pl) * 1996-09-04 2004-12-31 Abbott Lab Pochodne erytromycyny, sposób wytwarzania pochodnych erytromycyny i środek o działaniu przeciwbakteryjnym
FR2757168B1 (fr) * 1996-12-12 1999-06-11 Hoechst Marion Roussel Inc Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
FR2760017B1 (fr) * 1997-02-27 1999-04-30 Hoechst Marion Roussel Inc Nouveaux derives de l'erytromycine, leur procede de preparation et leur application comme medicaments
US6165986A (en) * 1997-03-10 2000-12-26 Taisho Pharmaceutical Co., Ltd. Erythromycin a derivatives
US6140479A (en) * 1997-03-24 2000-10-31 Taisho Pharmaceuticals Co., Ltd. Erythromycin a derivatives
US6162794A (en) * 1997-05-09 2000-12-19 Pfizer Inc. Erythromycin derivatives
US5922683A (en) * 1997-05-29 1999-07-13 Abbott Laboratories Multicyclic erythromycin derivatives
ID24529A (id) * 1997-06-11 2000-07-20 Pfizer Prod Inc Turunan-turunan 9-oksima eritromisin
FR2771008B1 (fr) * 1997-11-17 2000-04-28 Hoechst Marion Roussel Inc Utilisation des ketolides pour la preparation de compositions pharmaceutiques destinees a prevenir les complications thrombotiques arterielles liees a l'atherosclerose
AP1060A (en) * 1998-01-02 2002-04-23 Pfizer Prod Inc Novel erythromycin derivatives.
EP1115732B1 (en) * 1998-09-22 2005-06-29 Pfizer Products Inc. Carbamate and carbazate ketolide antibiotics
FR2786188B1 (fr) * 1998-11-24 2002-10-31 Hoechst Marion Roussel Inc Nouveaux derives de l'erythromycine, leur procede de preparation et leur applicaion comme medicaments
EP1298138B1 (en) * 1998-12-10 2006-11-02 Pfizer Products Inc. Carbamate and Carbazate Ketolide Antibiotics
EP1137654A1 (en) 1998-12-10 2001-10-04 Pfizer Products Inc. Carbamate and carbazate ketolide antibiotics
EP1749832A3 (en) * 1998-12-10 2008-03-26 Pfizer Products Incorporated Carbamate and carbazate ketolide antibiotics
FR2789392B1 (fr) * 1999-02-04 2001-10-05 Hoechst Marion Roussel Inc Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
US6054435A (en) * 1999-03-19 2000-04-25 Abbott Laboratories 6-O-substituted macrolides having antibacterial activity
US6590083B1 (en) 1999-04-16 2003-07-08 Ortho-Mcneil Pharmaceutical, Inc. Ketolide antibacterials
JP2002542197A (ja) 1999-04-16 2002-12-10 オーソ−マクニール・フアーマシユーチカル・インコーポレーテツド ケトライド抗菌剤
DE60030847T2 (de) * 1999-04-16 2007-04-19 Kosan Biosciences, Inc., Hayward Antiinfektiöse makrolidderivate
AP2001002302A0 (en) * 1999-05-24 2001-10-25 Pfizer Prod Inc 13-Methyl erythromycin derivatives.
AU2002316550A1 (en) 2001-07-03 2003-01-21 Chiron Corporation C12 modified erythromycin macrolides and ketolides having antibacterial activity
AU2003280305B2 (en) 2002-07-01 2008-05-01 Arkion Life Sciences Llc Process and materials for production of glucosamine and N-acetylglucosamine
ES2552682T3 (es) 2003-03-10 2015-12-01 Merck Sharp & Dohme Corp. Agentes antibacterianos novedosos
EP1618119A2 (en) * 2003-04-25 2006-01-25 Chiron Corporation Pyridyl substituted ketolide antibiotics
WO2004096823A2 (en) * 2003-04-25 2004-11-11 Chiron Corporation Novel ketolide derivatives
EP2214484A4 (en) 2007-10-25 2013-01-02 Cempra Pharmaceuticals Inc PROCESS FOR PREPARING ANTIBACTERIAL MAKROLIDE AGENTS
EP2358379B1 (en) * 2008-10-24 2015-12-16 Cempra Pharmaceuticals, Inc. Biodefenses using triazole-containing macrolides
US9937194B1 (en) 2009-06-12 2018-04-10 Cempra Pharmaceuticals, Inc. Compounds and methods for treating inflammatory diseases
US9480679B2 (en) 2009-09-10 2016-11-01 Cempra Pharmaceuticals, Inc. Methods for treating malaria, tuberculosis and MAC diseases
DK2550286T3 (en) 2010-03-22 2016-02-29 Cempra Pharmaceuticals Inc CRYSTALLINE FORMS OF A MACROLID AND APPLICATIONS THEREOF
EP2571506B1 (en) 2010-05-20 2017-05-10 Cempra Pharmaceuticals, Inc. Processes for preparing macrolides and ketolides and intermediates therefor
EP2613630A4 (en) 2010-09-10 2014-01-15 Cempra Pharmaceuticals Inc FLUOROCETOLIDES FORMING HYDROGEN LINKS TO TREAT DISEASES
KR20140139083A (ko) 2012-03-27 2014-12-04 셈프라 파마슈티컬스, 인크. 마크롤라이드계 항생제를 투여하기 위한 비경구 제제
JP6426696B2 (ja) 2013-03-14 2018-11-21 センプラ ファーマシューティカルズ，インコーポレイテッド 呼吸器疾患の治療のための方法および製剤
EP2968384A4 (en) 2013-03-15 2017-02-15 Cempra Pharmaceuticals, Inc. Convergent processes for preparing macrolide antibacterial agents
CN111825733A (zh) 2013-04-04 2020-10-27 哈佛大学的校长及成员们 大环内酯及其制备和使用方法
CN106998685A (zh) 2014-10-08 2017-08-01 哈佛大学的校长及成员们 14‑元酮内酯及其制备和使用方法
CN107530365A (zh) 2015-03-25 2018-01-02 哈佛大学的校长及成员们 具有修饰的脱氧糖胺糖的大环内酯及其用途
MD1222Z (ro) * 2017-05-31 2018-08-31 ИНСТИТУТ ЭЛЕКТРОННОЙ ИНЖЕНЕРИИ И НАНОТЕХНОЛОГИЙ "D. Ghitu" АНМ Procedeu de tratare a materialului săditor al florilor înainte de plantare
JP7199722B2 (ja) 2019-12-25 2023-01-06 旭精工株式会社 硬貨搬送振分機構及びそれを備えた硬貨識別搬送装置

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3868414A (en) * 1973-01-22 1975-02-25 Merck & Co Inc Tetrahydrofluorene carboxylic acids and related compounds
DE2842759A1 (de) * 1978-09-30 1980-04-10 Merck Patent Gmbh Basische aether, diese enthaltende pharmazeutische zubereitungen und verfahren zu ihrer herstellung
IL99995A (en) * 1990-11-21 1997-11-20 Roussel Uclaf Erythromycin derivatives, their preparation and pharmaceutical compositions containing them
FR2692579B1 (fr) * 1992-06-19 1995-06-02 Roussel Uclaf Nouveaux dérivés de la picromycine, leur procédé de préparation et leur application comme médicaments.
US5527780A (en) * 1992-11-05 1996-06-18 Roussel Uclaf Erythromycin derivatives
FR2697524B1 (fr) * 1992-11-05 1994-12-23 Roussel Uclaf Nouveaux dérivés de l'érythromycine, leur procédé de préparation et leur application comme médicaments.
HRP930014A2 (en) * 1993-01-08 1994-08-31 Pliva Pharm & Chem Works 9-deoxo-9a-aza-11-deoxy-9a-homoeritromycin a 9a, 11-cyclic carbamates
FR2702480B1 (fr) * 1993-03-09 1995-04-28 Roussel Uclaf Nouveaux dérivés de l'érythromycine, leur procédé de préparation et leur application comme médicaments.

Also Published As

Publication number Publication date
HU215396B (hu) 1998-12-28
TW316908B (et) 1997-10-01
GEP19991836B (en) 1999-11-05
AU2310795A (en) 1995-10-30
ES2189820T3 (es) 2003-07-16
TNSN95026A1 (fr) 1996-02-06
CA2164638C (fr) 2003-12-30
FR2718450A1 (fr) 1995-10-13
UA44705C2 (uk) 2002-03-15
NO308361B1 (no) 2000-09-04
RU2141965C1 (ru) 1999-11-27
GB9506856D0 (en) 1995-05-24
DZ1869A1 (fr) 2002-02-17
MD663G2 (ro) 1997-07-31
SK154695A3 (en) 1996-10-02
LV11182B (en) 1997-04-20
US5760233A (en) 1998-06-02
CZ296005B6 (cs) 2005-12-14
SI0676409T1 (en) 2003-06-30
AU684939B2 (en) 1998-01-08
ATE234853T1 (de) 2003-04-15
HUT73772A (en) 1996-09-30
NO954942D0 (no) 1995-12-06
NZ284498A (en) 1997-07-27
IL112954A0 (en) 1995-06-29
PE2896A1 (es) 1996-02-12
EP0676409A1 (fr) 1995-10-11
LV11182A (lv) 1996-04-20
IS1865B (is) 2003-05-02
FI955913A0 (fi) 1995-12-08
RO115634B1 (ro) 2000-04-28
FI955913A (fi) 1995-12-08
AP9500743A0 (en) 1995-07-31
CA2164638A1 (fr) 1995-10-19
EP0676409B1 (fr) 2003-03-19
SA97170757A (ar) 2005-12-03
KR100317148B1 (ko) 2002-06-22
WO1995027720A1 (fr) 1995-10-19
US5656607A (en) 1997-08-12
SK284079B6 (sk) 2004-09-08
FI111264B (fi) 2003-06-30
HRP950217B1 (en) 2004-06-30
BR9506147A (pt) 1996-04-16
CZ322395A3 (en) 1996-08-14
DE69529934T2 (de) 2003-09-04
BG100150A (bg) 1996-06-28
AP587A (en) 1997-04-29
PL311871A1 (en) 1996-03-18
PT676409E (pt) 2003-08-29
IL112954A (en) 2000-07-16
EE9500080A (et) 1996-12-16
HRP950217A2 (en) 1997-08-31
MA23501A1 (fr) 1995-12-31
JO1850B1 (en) 1995-12-27
CN1126997A (zh) 1996-07-17
CN1059445C (zh) 2000-12-13
CO4370097A1 (es) 1996-10-07
FR2718450B1 (fr) 1997-01-10
DE69529934D1 (de) 2003-04-24
JPH07278177A (ja) 1995-10-24
GB2288174A (en) 1995-10-11
BG61916B1 (bg) 1998-09-30
YU49221B (sh) 2004-11-25
PL180837B1 (pl) 2001-04-30
IS4309A (is) 1995-11-17
NO954942L (no) 1996-02-07
YU21695A (sh) 1997-12-05
ZA952059B (en) 1996-03-13
OA10200A (fr) 1996-12-18
MD663F1 (ro) 1997-01-31
HU9503505D0 (en) 1996-02-28
MY114672A (en) 2002-12-31
JP3000023B2 (ja) 2000-01-17
DK0676409T3 (da) 2003-06-23
SV1995000018A (es) 1997-10-24

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