PT676409E - Novos derivados da eritromicina seu processo de preparacao e sua aplicacao como medicamentos - Google Patents

Novos derivados da eritromicina seu processo de preparacao e sua aplicacao como medicamentos

Info

Publication number
PT676409E
PT676409E PT95400763T PT95400763T PT676409E PT 676409 E PT676409 E PT 676409E PT 95400763 T PT95400763 T PT 95400763T PT 95400763 T PT95400763 T PT 95400763T PT 676409 E PT676409 E PT 676409E
Authority
PT
Portugal
Prior art keywords
erythromycine
medicines
application
preparation process
new derivatives
Prior art date
Application number
PT95400763T
Other languages
English (en)
Inventor
Alexis Denis
Constantin Agouridas
Jean-Francois Chantot
Yannick Benedetti
Odile Le Martret
Original Assignee
Aventis Pharma Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Sa filed Critical Aventis Pharma Sa
Publication of PT676409E publication Critical patent/PT676409E/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
PT95400763T 1994-04-08 1995-04-06 Novos derivados da eritromicina seu processo de preparacao e sua aplicacao como medicamentos PT676409E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9404154A FR2718450B1 (fr) 1994-04-08 1994-04-08 Nouveaux dérivés de l'érythromycine, leur procédé de préparation et leur application comme médicaments.

Publications (1)

Publication Number Publication Date
PT676409E true PT676409E (pt) 2003-08-29

Family

ID=9461886

Family Applications (1)

Application Number Title Priority Date Filing Date
PT95400763T PT676409E (pt) 1994-04-08 1995-04-06 Novos derivados da eritromicina seu processo de preparacao e sua aplicacao como medicamentos

Country Status (49)

Country Link
US (2) US5656607A (pt)
EP (1) EP0676409B1 (pt)
JP (1) JP3000023B2 (pt)
KR (1) KR100317148B1 (pt)
CN (1) CN1059445C (pt)
AP (1) AP587A (pt)
AT (1) ATE234853T1 (pt)
AU (1) AU684939B2 (pt)
BG (1) BG61916B1 (pt)
BR (1) BR9506147A (pt)
CA (1) CA2164638C (pt)
CO (1) CO4370097A1 (pt)
CZ (1) CZ296005B6 (pt)
DE (1) DE69529934T2 (pt)
DK (1) DK0676409T3 (pt)
DZ (1) DZ1869A1 (pt)
EE (1) EE04498B1 (pt)
ES (1) ES2189820T3 (pt)
FI (1) FI111264B (pt)
FR (1) FR2718450B1 (pt)
GB (1) GB2288174A (pt)
GE (1) GEP19991836B (pt)
HR (1) HRP950217B1 (pt)
HU (1) HU215396B (pt)
IL (1) IL112954A (pt)
IS (1) IS1865B (pt)
JO (1) JO1850B1 (pt)
LV (1) LV11182B (pt)
MA (1) MA23501A1 (pt)
MD (1) MD663G2 (pt)
MY (1) MY114672A (pt)
NO (1) NO308361B1 (pt)
NZ (1) NZ284498A (pt)
OA (1) OA10200A (pt)
PE (1) PE2896A1 (pt)
PL (1) PL180837B1 (pt)
PT (1) PT676409E (pt)
RO (1) RO115634B1 (pt)
RU (1) RU2141965C1 (pt)
SA (1) SA97170757A (pt)
SI (1) SI0676409T1 (pt)
SK (1) SK284079B6 (pt)
SV (1) SV1995000018A (pt)
TN (1) TNSN95026A1 (pt)
TW (1) TW316908B (pt)
UA (1) UA44705C2 (pt)
WO (1) WO1995027720A1 (pt)
YU (1) YU49221B (pt)
ZA (1) ZA952059B (pt)

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FR2742757B1 (fr) 1995-12-22 1998-01-30 Roussel Uclaf Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
FR2745289B1 (fr) * 1996-02-28 1998-05-29 Roussel Uclaf Nouveaux derives de l'acide 1(2h) quinoleine carboxylique, leur procede de preparation et leur application a la synthese de produits doues de proprietes antibiotiques
US5750510A (en) * 1997-04-04 1998-05-12 Abbott Laboratories 3-descladinose-2,3-anhydroerythromycin derivatives
ATE246199T1 (de) * 1996-05-07 2003-08-15 Abbott Lab 3-descladinose-2,3-anhydroerythromycin-derivate
FR2748746B1 (fr) * 1996-05-14 1998-08-14 Hoechst Marion Roussel Inc Nouveau procede d'isomerisation du radical methyle en 10 de derives de l'erythromycine
FR2751656B1 (fr) * 1996-07-24 1998-10-16 Hoechst Marion Roussel Inc Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
BR9711661A (pt) * 1996-09-04 1999-08-24 Abbott Lab Composto composi-Æo farmac-utica e processos para controlar uma infec-Æo bacteriana em um mam¡fero e para preparar um composto
UA51730C2 (uk) * 1996-09-04 2002-12-16 Ебботт Лабораторіз 6-o-заміщені кетоліди з антибактеріальною активністю, спосіб їх одержання (варіанти), фармацевтична композиція та спосіб регулювання бактеріальної інфекції у ссавців
FR2757168B1 (fr) * 1996-12-12 1999-06-11 Hoechst Marion Roussel Inc Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
FR2760017B1 (fr) * 1997-02-27 1999-04-30 Hoechst Marion Roussel Inc Nouveaux derives de l'erytromycine, leur procede de preparation et leur application comme medicaments
AU4472897A (en) * 1997-03-10 1998-09-29 Taisho Pharmaceutical Co., Ltd. Erythromycin a derivatives
WO1998042720A1 (fr) * 1997-03-24 1998-10-01 Taisho Pharmaceutical Co., Ltd. Derives d'erythromycine a
US6162794A (en) * 1997-05-09 2000-12-19 Pfizer Inc. Erythromycin derivatives
US5922683A (en) * 1997-05-29 1999-07-13 Abbott Laboratories Multicyclic erythromycin derivatives
CZ9904388A3 (cs) * 1997-06-11 2002-10-16 Pfizer Products Inc. 9-Oximové deriváty erythromycinu
FR2771008B1 (fr) * 1997-11-17 2000-04-28 Hoechst Marion Roussel Inc Utilisation des ketolides pour la preparation de compositions pharmaceutiques destinees a prevenir les complications thrombotiques arterielles liees a l'atherosclerose
AP1060A (en) * 1998-01-02 2002-04-23 Pfizer Prod Inc Novel erythromycin derivatives.
DE69926005T2 (de) 1998-09-22 2006-05-18 Pfizer Products Inc., Groton Carbamat- und carbazatketolidantibiotika
FR2786188B1 (fr) * 1998-11-24 2002-10-31 Hoechst Marion Roussel Inc Nouveaux derives de l'erythromycine, leur procede de preparation et leur applicaion comme medicaments
ATE344269T1 (de) 1998-12-10 2006-11-15 Pfizer Prod Inc Carbamat und carbazat ketolid antibiotika
EP1749832A3 (en) * 1998-12-10 2008-03-26 Pfizer Products Incorporated Carbamate and carbazate ketolide antibiotics
EP1298138B1 (en) * 1998-12-10 2006-11-02 Pfizer Products Inc. Carbamate and Carbazate Ketolide Antibiotics
FR2789392B1 (fr) * 1999-02-04 2001-10-05 Hoechst Marion Roussel Inc Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
US6054435A (en) * 1999-03-19 2000-04-25 Abbott Laboratories 6-O-substituted macrolides having antibacterial activity
US6590083B1 (en) 1999-04-16 2003-07-08 Ortho-Mcneil Pharmaceutical, Inc. Ketolide antibacterials
WO2000062783A2 (en) 1999-04-16 2000-10-26 Ortho-Mcneil Pharmaceutical, Inc. Ketolide antibacterials
BR0010680A (pt) * 1999-04-16 2002-02-19 Kosan Biosciences Inc Agentes antiinfecciosos de macrolìdeo
IL145739A0 (en) * 1999-05-24 2002-07-25 Pfizer Prod Inc 13-methyl-erythromycin derivatives
WO2003004509A2 (en) * 2001-07-03 2003-01-16 Chiron Corporation C12 modified erythromycin macrolides and ketolides having antibacterial activity
JP2006508643A (ja) 2002-07-01 2006-03-16 アーキオン ライフ サイエンシーズ エルエルシー ディー／ビー／エー バイオ−テクニカル リソーセズ ディビジョン グルコサミンおよびｎ−アセチルグルコサミン製造のためのプロセスおよび材料
EP3738591A3 (en) 2003-03-10 2021-03-24 Merck Sharp & Dohme Corp. Novel antibacterial agents
CA2523134A1 (en) * 2003-04-25 2004-11-11 Chiron Corporation Pyridyl substituted ketolide antibiotics
JP2006524706A (ja) * 2003-04-25 2006-11-02 カイロン コーポレイション 新規なケトライド誘導体
CN101917850B (zh) 2007-10-25 2016-01-13 森普拉制药公司 大环内酯类抗菌剂的制备方法
SI2358379T1 (sl) 2008-10-24 2016-05-31 Cempra Pharmaceuticals, Inc. Postopki biološke obrambe z makrolidi, ki vsebujejo triazol
US9937194B1 (en) 2009-06-12 2018-04-10 Cempra Pharmaceuticals, Inc. Compounds and methods for treating inflammatory diseases
CN102724874B (zh) 2009-09-10 2018-06-01 森普拉制药公司 治疗疟疾、结核病和mac疾病的方法
KR20180101643A (ko) 2010-03-22 2018-09-12 셈프라 파마슈티컬스, 인크. 매크로라이드의 결정 형태들 및 그 용도들
CN102917708B (zh) 2010-05-20 2015-11-25 森普拉制药公司 制备大环内酯和酮内酯及其中间体的方法
KR20180110181A (ko) 2010-09-10 2018-10-08 셈프라 파마슈티컬스, 인크. 질환을 치료하기 위한 수소결합 형성 플루오로 케토라이드
KR20140139083A (ko) 2012-03-27 2014-12-04 셈프라 파마슈티컬스, 인크. 마크롤라이드계 항생제를 투여하기 위한 비경구 제제
US9861616B2 (en) 2013-03-14 2018-01-09 Cempra Pharmaceuticals, Inc. Methods for treating respiratory diseases and formulations therefor
RU2015138797A (ru) 2013-03-15 2017-04-24 Семпра Фармасьютикалс, Инк. Конвергентные способы получения макролидных антибактериальных агентов
EP2988597B1 (en) 2013-04-04 2022-06-08 President and Fellows of Harvard College Macrolides and methods of their preparation and use
CN106998685A (zh) 2014-10-08 2017-08-01 哈佛大学的校长及成员们 14‑元酮内酯及其制备和使用方法
JP2018509452A (ja) 2015-03-25 2018-04-05 プレジデント アンド フェローズ オブ ハーバード カレッジ 修飾デソサミン糖をもつマクロライドおよびその使用
MD1222Z (ro) * 2017-05-31 2018-08-31 ИНСТИТУТ ЭЛЕКТРОННОЙ ИНЖЕНЕРИИ И НАНОТЕХНОЛОГИЙ "D. Ghitu" АНМ Procedeu de tratare a materialului săditor al florilor înainte de plantare
JP7199722B2 (ja) 2019-12-25 2023-01-06 旭精工株式会社 硬貨搬送振分機構及びそれを備えた硬貨識別搬送装置

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US3868414A (en) * 1973-01-22 1975-02-25 Merck & Co Inc Tetrahydrofluorene carboxylic acids and related compounds
DE2842759A1 (de) * 1978-09-30 1980-04-10 Merck Patent Gmbh Basische aether, diese enthaltende pharmazeutische zubereitungen und verfahren zu ihrer herstellung
IL99995A (en) * 1990-11-21 1997-11-20 Roussel Uclaf Erythromycin derivatives, their preparation and pharmaceutical compositions containing them
FR2692579B1 (fr) * 1992-06-19 1995-06-02 Roussel Uclaf Nouveaux dérivés de la picromycine, leur procédé de préparation et leur application comme médicaments.
FR2697524B1 (fr) * 1992-11-05 1994-12-23 Roussel Uclaf Nouveaux dérivés de l'érythromycine, leur procédé de préparation et leur application comme médicaments.
US5527780A (en) * 1992-11-05 1996-06-18 Roussel Uclaf Erythromycin derivatives
HRP930014A2 (en) * 1993-01-08 1994-08-31 Pliva Pharm & Chem Works 9-deoxo-9a-aza-11-deoxy-9a-homoeritromycin a 9a, 11-cyclic carbamates
FR2702480B1 (fr) * 1993-03-09 1995-04-28 Roussel Uclaf Nouveaux dérivés de l'érythromycine, leur procédé de préparation et leur application comme médicaments.

Also Published As

Publication number Publication date
PE2896A1 (es) 1996-02-12
SV1995000018A (es) 1997-10-24
GB2288174A (en) 1995-10-11
CN1059445C (zh) 2000-12-13
IS1865B (is) 2003-05-02
ES2189820T3 (es) 2003-07-16
RO115634B1 (ro) 2000-04-28
EE04498B1 (et) 2005-06-15
LV11182A (lv) 1996-04-20
MA23501A1 (fr) 1995-12-31
SI0676409T1 (en) 2003-06-30
DE69529934T2 (de) 2003-09-04
WO1995027720A1 (fr) 1995-10-19
EP0676409B1 (fr) 2003-03-19
US5656607A (en) 1997-08-12
AP587A (en) 1997-04-29
ZA952059B (en) 1996-03-13
TNSN95026A1 (fr) 1996-02-06
NO954942D0 (no) 1995-12-06
HU215396B (hu) 1998-12-28
PL311871A1 (en) 1996-03-18
CZ322395A3 (en) 1996-08-14
CA2164638A1 (fr) 1995-10-19
US5760233A (en) 1998-06-02
AU684939B2 (en) 1998-01-08
FI955913A (fi) 1995-12-08
HU9503505D0 (en) 1996-02-28
OA10200A (fr) 1996-12-18
JP3000023B2 (ja) 2000-01-17
YU21695A (sh) 1997-12-05
EE9500080A (et) 1996-12-16
AP9500743A0 (en) 1995-07-31
GB9506856D0 (en) 1995-05-24
PL180837B1 (pl) 2001-04-30
HRP950217B1 (en) 2004-06-30
DZ1869A1 (fr) 2002-02-17
MY114672A (en) 2002-12-31
YU49221B (sh) 2004-11-25
CN1126997A (zh) 1996-07-17
HRP950217A2 (en) 1997-08-31
BG61916B1 (bg) 1998-09-30
NO308361B1 (no) 2000-09-04
SK154695A3 (en) 1996-10-02
FI111264B (fi) 2003-06-30
SK284079B6 (sk) 2004-09-08
IL112954A (en) 2000-07-16
BG100150A (bg) 1996-06-28
CZ296005B6 (cs) 2005-12-14
FI955913A0 (fi) 1995-12-08
FR2718450B1 (fr) 1997-01-10
JPH07278177A (ja) 1995-10-24
KR100317148B1 (ko) 2002-06-22
EP0676409A1 (fr) 1995-10-11
DE69529934D1 (de) 2003-04-24
GEP19991836B (en) 1999-11-05
RU2141965C1 (ru) 1999-11-27
IS4309A (is) 1995-11-17
SA97170757A (ar) 2005-12-03
UA44705C2 (uk) 2002-03-15
TW316908B (pt) 1997-10-01
MD663G2 (ro) 1997-07-31
ATE234853T1 (de) 2003-04-15
HUT73772A (en) 1996-09-30
NO954942L (no) 1996-02-07
FR2718450A1 (fr) 1995-10-13
CA2164638C (fr) 2003-12-30
BR9506147A (pt) 1996-04-16
LV11182B (en) 1997-04-20
JO1850B1 (en) 1995-12-27
IL112954A0 (en) 1995-06-29
DK0676409T3 (da) 2003-06-23
AU2310795A (en) 1995-10-30
NZ284498A (en) 1997-07-27
MD663F1 (ro) 1997-01-31
CO4370097A1 (es) 1996-10-07

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