NO954942L - Nye erytromycinderivater, fremgangsmåte for deres fremstilling og anvendelse av derivatene som legemidler - Google Patents

Nye erytromycinderivater, fremgangsmåte for deres fremstilling og anvendelse av derivatene som legemidler

Info

Publication number
NO954942L
NO954942L NO954942A NO954942A NO954942L NO 954942 L NO954942 L NO 954942L NO 954942 A NO954942 A NO 954942A NO 954942 A NO954942 A NO 954942A NO 954942 L NO954942 L NO 954942L
Authority
NO
Norway
Prior art keywords
derivatives
drugs
processes
preparation
new erythromycin
Prior art date
Application number
NO954942A
Other languages
English (en)
Other versions
NO308361B1 (no
NO954942D0 (no
Inventor
Constantin Agouridas
Yannick Benedetti
Jean-Francois Chantot
Alexis Denis
Odile Le Martret
Original Assignee
Roussel Uclaf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf filed Critical Roussel Uclaf
Publication of NO954942D0 publication Critical patent/NO954942D0/no
Publication of NO954942L publication Critical patent/NO954942L/no
Publication of NO308361B1 publication Critical patent/NO308361B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
NO954942A 1994-04-08 1995-12-06 Nye erytromycinderivater, samt legemidler som inneholder slike NO308361B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9404154A FR2718450B1 (fr) 1994-04-08 1994-04-08 Nouveaux dérivés de l'érythromycine, leur procédé de préparation et leur application comme médicaments.
PCT/FR1995/000441 WO1995027720A1 (fr) 1994-04-08 1995-04-06 Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments

Publications (3)

Publication Number Publication Date
NO954942D0 NO954942D0 (no) 1995-12-06
NO954942L true NO954942L (no) 1996-02-07
NO308361B1 NO308361B1 (no) 2000-09-04

Family

ID=9461886

Family Applications (1)

Application Number Title Priority Date Filing Date
NO954942A NO308361B1 (no) 1994-04-08 1995-12-06 Nye erytromycinderivater, samt legemidler som inneholder slike

Country Status (49)

Country Link
US (2) US5656607A (no)
EP (1) EP0676409B1 (no)
JP (1) JP3000023B2 (no)
KR (1) KR100317148B1 (no)
CN (1) CN1059445C (no)
AP (1) AP587A (no)
AT (1) ATE234853T1 (no)
AU (1) AU684939B2 (no)
BG (1) BG61916B1 (no)
BR (1) BR9506147A (no)
CA (1) CA2164638C (no)
CO (1) CO4370097A1 (no)
CZ (1) CZ296005B6 (no)
DE (1) DE69529934T2 (no)
DK (1) DK0676409T3 (no)
DZ (1) DZ1869A1 (no)
EE (1) EE04498B1 (no)
ES (1) ES2189820T3 (no)
FI (1) FI111264B (no)
FR (1) FR2718450B1 (no)
GB (1) GB2288174A (no)
GE (1) GEP19991836B (no)
HR (1) HRP950217B1 (no)
HU (1) HU215396B (no)
IL (1) IL112954A (no)
IS (1) IS1865B (no)
JO (1) JO1850B1 (no)
LV (1) LV11182B (no)
MA (1) MA23501A1 (no)
MD (1) MD663G2 (no)
MY (1) MY114672A (no)
NO (1) NO308361B1 (no)
NZ (1) NZ284498A (no)
OA (1) OA10200A (no)
PE (1) PE2896A1 (no)
PL (1) PL180837B1 (no)
PT (1) PT676409E (no)
RO (1) RO115634B1 (no)
RU (1) RU2141965C1 (no)
SA (1) SA97170757A (no)
SI (1) SI0676409T1 (no)
SK (1) SK284079B6 (no)
SV (1) SV1995000018A (no)
TN (1) TNSN95026A1 (no)
TW (1) TW316908B (no)
UA (1) UA44705C2 (no)
WO (1) WO1995027720A1 (no)
YU (1) YU49221B (no)
ZA (1) ZA952059B (no)

Families Citing this family (49)

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FR2732023B1 (fr) * 1995-03-22 1997-04-30 Roussel Uclaf Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
FR2742757B1 (fr) * 1995-12-22 1998-01-30 Roussel Uclaf Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
FR2745289B1 (fr) * 1996-02-28 1998-05-29 Roussel Uclaf Nouveaux derives de l'acide 1(2h) quinoleine carboxylique, leur procede de preparation et leur application a la synthese de produits doues de proprietes antibiotiques
JP2002502366A (ja) * 1996-05-07 2002-01-22 アボット・ラボラトリーズ ３―デスクラジノース―２，３―無水エリスロマイシン誘導体
US5750510A (en) * 1997-04-04 1998-05-12 Abbott Laboratories 3-descladinose-2,3-anhydroerythromycin derivatives
FR2748746B1 (fr) * 1996-05-14 1998-08-14 Hoechst Marion Roussel Inc Nouveau procede d'isomerisation du radical methyle en 10 de derives de l'erythromycine
FR2751656B1 (fr) * 1996-07-24 1998-10-16 Hoechst Marion Roussel Inc Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
WO1998009978A1 (en) * 1996-09-04 1998-03-12 Abbott Laboratories 6-o-substituted ketolides having antibacterial activity
UA51730C2 (uk) * 1996-09-04 2002-12-16 Ебботт Лабораторіз 6-o-заміщені кетоліди з антибактеріальною активністю, спосіб їх одержання (варіанти), фармацевтична композиція та спосіб регулювання бактеріальної інфекції у ссавців
FR2757168B1 (fr) * 1996-12-12 1999-06-11 Hoechst Marion Roussel Inc Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
FR2760017B1 (fr) * 1997-02-27 1999-04-30 Hoechst Marion Roussel Inc Nouveaux derives de l'erytromycine, leur procede de preparation et leur application comme medicaments
US6165986A (en) * 1997-03-10 2000-12-26 Taisho Pharmaceutical Co., Ltd. Erythromycin a derivatives
WO1998042720A1 (fr) * 1997-03-24 1998-10-01 Taisho Pharmaceutical Co., Ltd. Derives d'erythromycine a
WO1998051696A1 (en) * 1997-05-09 1998-11-19 Pfizer Products Inc. Erythromycin derivatives
US5922683A (en) * 1997-05-29 1999-07-13 Abbott Laboratories Multicyclic erythromycin derivatives
EP0988308A1 (en) * 1997-06-11 2000-03-29 Pfizer Products Inc. 9-oxime erythromycin derivatives
FR2771008B1 (fr) * 1997-11-17 2000-04-28 Hoechst Marion Roussel Inc Utilisation des ketolides pour la preparation de compositions pharmaceutiques destinees a prevenir les complications thrombotiques arterielles liees a l'atherosclerose
AP1060A (en) * 1998-01-02 2002-04-23 Pfizer Prod Inc Novel erythromycin derivatives.
EP1115732B1 (en) 1998-09-22 2005-06-29 Pfizer Products Inc. Carbamate and carbazate ketolide antibiotics
FR2786188B1 (fr) * 1998-11-24 2002-10-31 Hoechst Marion Roussel Inc Nouveaux derives de l'erythromycine, leur procede de preparation et leur applicaion comme medicaments
ATE344269T1 (de) 1998-12-10 2006-11-15 Pfizer Prod Inc Carbamat und carbazat ketolid antibiotika
EP1298138B1 (en) * 1998-12-10 2006-11-02 Pfizer Products Inc. Carbamate and Carbazate Ketolide Antibiotics
EP1749832A3 (en) * 1998-12-10 2008-03-26 Pfizer Products Incorporated Carbamate and carbazate ketolide antibiotics
FR2789392B1 (fr) 1999-02-04 2001-10-05 Hoechst Marion Roussel Inc Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
US6054435A (en) * 1999-03-19 2000-04-25 Abbott Laboratories 6-O-substituted macrolides having antibacterial activity
US6590083B1 (en) 1999-04-16 2003-07-08 Ortho-Mcneil Pharmaceutical, Inc. Ketolide antibacterials
CN1373767A (zh) 1999-04-16 2002-10-09 奥索-麦克尼尔药品公司 酮式大环内酯抗菌剂
JP2003523938A (ja) * 1999-04-16 2003-08-12 コーサン バイオサイエンシーズ， インコーポレイテッド マクロライド系抗感染剤
OA11945A (en) * 1999-05-24 2006-04-13 Pfizer Prod Inc 13-Methyl erythromycin derivatives.
US6756359B2 (en) 2001-07-03 2004-06-29 Chiron Corporation C12 modified erythromycin macrolides and ketolides having antibacterial activity
WO2004003175A2 (en) 2002-07-01 2004-01-08 Arkion Life Sciences Llc Process and materials for production of glucosamine and n-acetylglucosamine
US7601695B2 (en) * 2003-03-10 2009-10-13 Optimer Pharmaceuticals, Inc. Antibacterial agents
US7163924B2 (en) * 2003-04-25 2007-01-16 Chiron Corporation Ketolide derivatives
CA2523134A1 (en) * 2003-04-25 2004-11-11 Chiron Corporation Pyridyl substituted ketolide antibiotics
CN105732745A (zh) * 2007-10-25 2016-07-06 森普拉制药公司 大环内酯类抗菌剂的制备方法
AU2009308180B2 (en) 2008-10-24 2016-01-07 Cempra Pharmaceuticals, Inc. Methods for treating gastrointestinal diseases
US9937194B1 (en) 2009-06-12 2018-04-10 Cempra Pharmaceuticals, Inc. Compounds and methods for treating inflammatory diseases
CN102724874B (zh) 2009-09-10 2018-06-01 森普拉制药公司 治疗疟疾、结核病和mac疾病的方法
ES2564097T3 (es) 2010-03-22 2016-03-17 Cempra Pharmaceuticals, Inc. Formas cristalinas de un macrólido, y usos de las mismas
EP2571506B1 (en) 2010-05-20 2017-05-10 Cempra Pharmaceuticals, Inc. Processes for preparing macrolides and ketolides and intermediates therefor
KR20180110181A (ko) 2010-09-10 2018-10-08 셈프라 파마슈티컬스, 인크. 질환을 치료하기 위한 수소결합 형성 플루오로 케토라이드
JP6208742B2 (ja) 2012-03-27 2017-10-04 センプラ ファーマシューティカルズ，インコーポレイテッド マクロライド抗生物質を投与するための非経口製剤
CN105163785A (zh) 2013-03-14 2015-12-16 森普拉制药公司 用于治疗呼吸道疾病的方法及其制剂
WO2014145210A1 (en) 2013-03-15 2014-09-18 Cempra Pharmaceuticals, Inc. Convergent processes for preparing macrolide antibacterial agents
CN111825733A (zh) 2013-04-04 2020-10-27 哈佛大学的校长及成员们 大环内酯及其制备和使用方法
WO2016057798A1 (en) * 2014-10-08 2016-04-14 President And Fellows Of Harvard College 14-membered ketolides and methods of their preparation and use
WO2016154591A1 (en) 2015-03-25 2016-09-29 President And Fellows Of Harvard College Macrolides with modified desosamine sugars and uses thereof
MD1222Z (ro) * 2017-05-31 2018-08-31 ИНСТИТУТ ЭЛЕКТРОННОЙ ИНЖЕНЕРИИ И НАНОТЕХНОЛОГИЙ "D. Ghitu" АНМ Procedeu de tratare a materialului săditor al florilor înainte de plantare
JP7199722B2 (ja) 2019-12-25 2023-01-06 旭精工株式会社 硬貨搬送振分機構及びそれを備えた硬貨識別搬送装置

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US3868414A (en) * 1973-01-22 1975-02-25 Merck & Co Inc Tetrahydrofluorene carboxylic acids and related compounds
DE2842759A1 (de) * 1978-09-30 1980-04-10 Merck Patent Gmbh Basische aether, diese enthaltende pharmazeutische zubereitungen und verfahren zu ihrer herstellung
IL99995A (en) * 1990-11-21 1997-11-20 Roussel Uclaf Erythromycin derivatives, their preparation and pharmaceutical compositions containing them
FR2692579B1 (fr) * 1992-06-19 1995-06-02 Roussel Uclaf Nouveaux dérivés de la picromycine, leur procédé de préparation et leur application comme médicaments.
FR2697524B1 (fr) * 1992-11-05 1994-12-23 Roussel Uclaf Nouveaux dérivés de l'érythromycine, leur procédé de préparation et leur application comme médicaments.
US5527780A (en) * 1992-11-05 1996-06-18 Roussel Uclaf Erythromycin derivatives
HRP930014A2 (en) * 1993-01-08 1994-08-31 Pliva Pharm & Chem Works 9-deoxo-9a-aza-11-deoxy-9a-homoeritromycin a 9a, 11-cyclic carbamates
FR2702480B1 (fr) * 1993-03-09 1995-04-28 Roussel Uclaf Nouveaux dérivés de l'érythromycine, leur procédé de préparation et leur application comme médicaments.

Also Published As

Publication number Publication date
YU21695A (sh) 1997-12-05
GB9506856D0 (en) 1995-05-24
HU9503505D0 (en) 1996-02-28
AU684939B2 (en) 1998-01-08
BR9506147A (pt) 1996-04-16
EP0676409A1 (fr) 1995-10-11
EE04498B1 (et) 2005-06-15
MA23501A1 (fr) 1995-12-31
DE69529934D1 (de) 2003-04-24
SI0676409T1 (en) 2003-06-30
ATE234853T1 (de) 2003-04-15
HUT73772A (en) 1996-09-30
SK284079B6 (sk) 2004-09-08
ZA952059B (en) 1996-03-13
RU2141965C1 (ru) 1999-11-27
WO1995027720A1 (fr) 1995-10-19
JP3000023B2 (ja) 2000-01-17
NO308361B1 (no) 2000-09-04
IS4309A (is) 1995-11-17
EP0676409B1 (fr) 2003-03-19
CA2164638C (fr) 2003-12-30
US5760233A (en) 1998-06-02
CA2164638A1 (fr) 1995-10-19
KR100317148B1 (ko) 2002-06-22
PE2896A1 (es) 1996-02-12
RO115634B1 (ro) 2000-04-28
DK0676409T3 (da) 2003-06-23
DE69529934T2 (de) 2003-09-04
MD663G2 (ro) 1997-07-31
CN1126997A (zh) 1996-07-17
ES2189820T3 (es) 2003-07-16
SV1995000018A (es) 1997-10-24
SA97170757A (ar) 2005-12-03
MY114672A (en) 2002-12-31
PL311871A1 (en) 1996-03-18
CZ296005B6 (cs) 2005-12-14
YU49221B (sh) 2004-11-25
HU215396B (hu) 1998-12-28
SK154695A3 (en) 1996-10-02
CO4370097A1 (es) 1996-10-07
PT676409E (pt) 2003-08-29
NO954942D0 (no) 1995-12-06
OA10200A (fr) 1996-12-18
TW316908B (no) 1997-10-01
EE9500080A (et) 1996-12-16
AU2310795A (en) 1995-10-30
TNSN95026A1 (fr) 1996-02-06
BG100150A (bg) 1996-06-28
BG61916B1 (bg) 1998-09-30
LV11182A (lv) 1996-04-20
CN1059445C (zh) 2000-12-13
PL180837B1 (pl) 2001-04-30
FI111264B (fi) 2003-06-30
DZ1869A1 (fr) 2002-02-17
IL112954A0 (en) 1995-06-29
UA44705C2 (uk) 2002-03-15
FI955913A (fi) 1995-12-08
HRP950217B1 (en) 2004-06-30
FR2718450A1 (fr) 1995-10-13
LV11182B (en) 1997-04-20
JO1850B1 (en) 1995-12-27
CZ322395A3 (en) 1996-08-14
IS1865B (is) 2003-05-02
GB2288174A (en) 1995-10-11
US5656607A (en) 1997-08-12
AP9500743A0 (en) 1995-07-31
NZ284498A (en) 1997-07-27
AP587A (en) 1997-04-29
IL112954A (en) 2000-07-16
FR2718450B1 (fr) 1997-01-10
GEP19991836B (en) 1999-11-05
FI955913A0 (fi) 1995-12-08
MD663F1 (ro) 1997-01-31
JPH07278177A (ja) 1995-10-24
HRP950217A2 (en) 1997-08-31

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