ZA952059B - Erythromycin derivatives their preparation process and their use as medicaments - Google Patents

Erythromycin derivatives their preparation process and their use as medicaments

Info

Publication number
ZA952059B
ZA952059B ZA952059A ZA952059A ZA952059B ZA 952059 B ZA952059 B ZA 952059B ZA 952059 A ZA952059 A ZA 952059A ZA 952059 A ZA952059 A ZA 952059A ZA 952059 B ZA952059 B ZA 952059B
Authority
ZA
South Africa
Prior art keywords
medicaments
preparation process
erythromycin derivatives
erythromycin
derivatives
Prior art date
Application number
ZA952059A
Other languages
English (en)
Inventor
Constantin Agouridas
Yannick Benedetti
Jean-Francois Chantot
Alexis Denis
Odile Le Martret
Original Assignee
Roussel Uclaf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf filed Critical Roussel Uclaf
Publication of ZA952059B publication Critical patent/ZA952059B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
ZA952059A 1994-04-08 1995-03-13 Erythromycin derivatives their preparation process and their use as medicaments ZA952059B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9404154A FR2718450B1 (fr) 1994-04-08 1994-04-08 Nouveaux dérivés de l'érythromycine, leur procédé de préparation et leur application comme médicaments.

Publications (1)

Publication Number Publication Date
ZA952059B true ZA952059B (en) 1996-03-13

Family

ID=9461886

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA952059A ZA952059B (en) 1994-04-08 1995-03-13 Erythromycin derivatives their preparation process and their use as medicaments

Country Status (49)

Country Link
US (2) US5656607A (no)
EP (1) EP0676409B1 (no)
JP (1) JP3000023B2 (no)
KR (1) KR100317148B1 (no)
CN (1) CN1059445C (no)
AP (1) AP587A (no)
AT (1) ATE234853T1 (no)
AU (1) AU684939B2 (no)
BG (1) BG61916B1 (no)
BR (1) BR9506147A (no)
CA (1) CA2164638C (no)
CO (1) CO4370097A1 (no)
CZ (1) CZ296005B6 (no)
DE (1) DE69529934T2 (no)
DK (1) DK0676409T3 (no)
DZ (1) DZ1869A1 (no)
EE (1) EE04498B1 (no)
ES (1) ES2189820T3 (no)
FI (1) FI111264B (no)
FR (1) FR2718450B1 (no)
GB (1) GB2288174A (no)
GE (1) GEP19991836B (no)
HR (1) HRP950217B1 (no)
HU (1) HU215396B (no)
IL (1) IL112954A (no)
IS (1) IS1865B (no)
JO (1) JO1850B1 (no)
LV (1) LV11182B (no)
MA (1) MA23501A1 (no)
MD (1) MD663G2 (no)
MY (1) MY114672A (no)
NO (1) NO308361B1 (no)
NZ (1) NZ284498A (no)
OA (1) OA10200A (no)
PE (1) PE2896A1 (no)
PL (1) PL180837B1 (no)
PT (1) PT676409E (no)
RO (1) RO115634B1 (no)
RU (1) RU2141965C1 (no)
SA (1) SA97170757A (no)
SI (1) SI0676409T1 (no)
SK (1) SK284079B6 (no)
SV (1) SV1995000018A (no)
TN (1) TNSN95026A1 (no)
TW (1) TW316908B (no)
UA (1) UA44705C2 (no)
WO (1) WO1995027720A1 (no)
YU (1) YU49221B (no)
ZA (1) ZA952059B (no)

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FR2732023B1 (fr) * 1995-03-22 1997-04-30 Roussel Uclaf Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
FR2742757B1 (fr) * 1995-12-22 1998-01-30 Roussel Uclaf Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
FR2745289B1 (fr) * 1996-02-28 1998-05-29 Roussel Uclaf Nouveaux derives de l'acide 1(2h) quinoleine carboxylique, leur procede de preparation et leur application a la synthese de produits doues de proprietes antibiotiques
IL126624A0 (en) * 1996-05-07 1999-08-17 Abbott Lab 3-descladinose-2, 3-anhydroerythromycin derivatives
US5750510A (en) * 1997-04-04 1998-05-12 Abbott Laboratories 3-descladinose-2,3-anhydroerythromycin derivatives
FR2748746B1 (fr) * 1996-05-14 1998-08-14 Hoechst Marion Roussel Inc Nouveau procede d'isomerisation du radical methyle en 10 de derives de l'erythromycine
FR2751656B1 (fr) * 1996-07-24 1998-10-16 Hoechst Marion Roussel Inc Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
KR100523679B1 (ko) * 1996-09-04 2005-10-26 아보트 러보러터리즈 항균 활성을 지닌 6-ｏ-치환된 케톨라이드
UA51730C2 (uk) * 1996-09-04 2002-12-16 Ебботт Лабораторіз 6-o-заміщені кетоліди з антибактеріальною активністю, спосіб їх одержання (варіанти), фармацевтична композиція та спосіб регулювання бактеріальної інфекції у ссавців
FR2757168B1 (fr) * 1996-12-12 1999-06-11 Hoechst Marion Roussel Inc Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
FR2760017B1 (fr) * 1997-02-27 1999-04-30 Hoechst Marion Roussel Inc Nouveaux derives de l'erytromycine, leur procede de preparation et leur application comme medicaments
AU4472897A (en) * 1997-03-10 1998-09-29 Taisho Pharmaceutical Co., Ltd. Erythromycin a derivatives
AU6421398A (en) * 1997-03-24 1998-10-20 Taisho Pharmaceutical Co., Ltd. Erythromycin a derivatives
AU6932098A (en) * 1997-05-09 1998-12-08 Pfizer Products Inc. Erythromycin derivatives
US5922683A (en) * 1997-05-29 1999-07-13 Abbott Laboratories Multicyclic erythromycin derivatives
EA199901016A1 (ru) * 1997-06-11 2000-06-26 Пфайзер Продактс Инк. 9-оксим-производные эритромицина
FR2771008B1 (fr) * 1997-11-17 2000-04-28 Hoechst Marion Roussel Inc Utilisation des ketolides pour la preparation de compositions pharmaceutiques destinees a prevenir les complications thrombotiques arterielles liees a l'atherosclerose
AP1060A (en) * 1998-01-02 2002-04-23 Pfizer Prod Inc Novel erythromycin derivatives.
ATE298761T1 (de) 1998-09-22 2005-07-15 Pfizer Prod Inc Carbamat- und carbazatketolidantibiotika
FR2786188B1 (fr) * 1998-11-24 2002-10-31 Hoechst Marion Roussel Inc Nouveaux derives de l'erythromycine, leur procede de preparation et leur applicaion comme medicaments
EP1298138B1 (en) * 1998-12-10 2006-11-02 Pfizer Products Inc. Carbamate and Carbazate Ketolide Antibiotics
ES2273964T3 (es) 1998-12-10 2007-05-16 Pfizer Products Inc. Antibioticos de carbamato y carbazato cetolida.
EP1749832A3 (en) * 1998-12-10 2008-03-26 Pfizer Products Incorporated Carbamate and carbazate ketolide antibiotics
FR2789392B1 (fr) 1999-02-04 2001-10-05 Hoechst Marion Roussel Inc Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
US6054435A (en) * 1999-03-19 2000-04-25 Abbott Laboratories 6-O-substituted macrolides having antibacterial activity
US6590083B1 (en) 1999-04-16 2003-07-08 Ortho-Mcneil Pharmaceutical, Inc. Ketolide antibacterials
ATE340183T1 (de) * 1999-04-16 2006-10-15 Kosan Biosciences Inc Antiinfektiöse makrolidderivate
WO2000062783A2 (en) 1999-04-16 2000-10-26 Ortho-Mcneil Pharmaceutical, Inc. Ketolide antibacterials
HUP0201516A3 (en) * 1999-05-24 2003-03-28 Pfizer Prod Inc 13-methyl-erythromycin derivatives, process for their preparation and pharmaceutical compositions containing them
US6756359B2 (en) 2001-07-03 2004-06-29 Chiron Corporation C12 modified erythromycin macrolides and ketolides having antibacterial activity
KR101035043B1 (ko) 2002-07-01 2011-05-19 아르키온 라이프 사이언씨즈 엘엘씨 글루코사민 및 ｎ-아세틸글루코사민의 제조를 위한 물질및 공정
EP1638549A4 (en) 2003-03-10 2011-06-15 Optimer Pharmaceuticals Inc NEW ANTIBACTERIAL AGENTS
US7163924B2 (en) * 2003-04-25 2007-01-16 Chiron Corporation Ketolide derivatives
US7332476B2 (en) * 2003-04-25 2008-02-19 Novartis Ag Pyridyl substituted ketolide antibiotics
EP2214484A4 (en) * 2007-10-25 2013-01-02 Cempra Pharmaceuticals Inc PROCESS FOR PREPARING ANTIBACTERIAL MAKROLIDE AGENTS
US8796232B2 (en) * 2008-10-24 2014-08-05 Cempra Pharmaceuticals, Inc. Methods for treating resistant diseases using triazole containing macrolides
US9937194B1 (en) 2009-06-12 2018-04-10 Cempra Pharmaceuticals, Inc. Compounds and methods for treating inflammatory diseases
AU2010292010B2 (en) 2009-09-10 2016-01-07 Cempra Pharmaceuticals, Inc. Methods for treating malaria, tuberculosis and MAC diseases
CN103080122A (zh) 2010-03-22 2013-05-01 森普拉制药公司 大环内脂的结晶形式及其用途
US9051346B2 (en) 2010-05-20 2015-06-09 Cempra Pharmaceuticals, Inc. Process for preparing triazole-containing ketolide antibiotics
JP6042334B2 (ja) 2010-09-10 2016-12-14 センプラ ファーマシューティカルズ，インコーポレイテッド 疾患治療のための水素結合形成フルオロケトライド
CN104470527B (zh) 2012-03-27 2019-05-28 森普拉制药公司 用于施用大环内酯抗生素的肠胃外制剂
WO2014152326A1 (en) 2013-03-14 2014-09-25 Cempra Pharmaceuticals, Inc. Methods for treating respiratory diseases and formulations therefor
US9751908B2 (en) 2013-03-15 2017-09-05 Cempra Pharmaceuticals, Inc. Convergent processes for preparing macrolide antibacterial agents
CA3130061A1 (en) 2013-04-04 2014-10-09 President And Fellows Of Harvard College Macrolides and methods of their preparation and use
JP2017531663A (ja) * 2014-10-08 2017-10-26 プレジデント アンド フェローズ オブ ハーバード カレッジ １４員ケトライドならびにそれらの調製および使用の方法
CA2980315A1 (en) 2015-03-25 2016-09-29 President And Fellows Of Harvard College Macrolides with modified desosamine sugars and uses thereof
MD1222Z (ro) * 2017-05-31 2018-08-31 ИНСТИТУТ ЭЛЕКТРОННОЙ ИНЖЕНЕРИИ И НАНОТЕХНОЛОГИЙ "D. Ghitu" АНМ Procedeu de tratare a materialului săditor al florilor înainte de plantare
JP7199722B2 (ja) 2019-12-25 2023-01-06 旭精工株式会社 硬貨搬送振分機構及びそれを備えた硬貨識別搬送装置

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US3868414A (en) * 1973-01-22 1975-02-25 Merck & Co Inc Tetrahydrofluorene carboxylic acids and related compounds
DE2842759A1 (de) * 1978-09-30 1980-04-10 Merck Patent Gmbh Basische aether, diese enthaltende pharmazeutische zubereitungen und verfahren zu ihrer herstellung
IL114589A (en) * 1990-11-21 1999-12-22 Roussel Uclaf Intermediates for the preparation of the history of erythromycin
FR2692579B1 (fr) * 1992-06-19 1995-06-02 Roussel Uclaf Nouveaux dérivés de la picromycine, leur procédé de préparation et leur application comme médicaments.
US5527780A (en) * 1992-11-05 1996-06-18 Roussel Uclaf Erythromycin derivatives
FR2697524B1 (fr) * 1992-11-05 1994-12-23 Roussel Uclaf Nouveaux dérivés de l'érythromycine, leur procédé de préparation et leur application comme médicaments.
HRP930014A2 (en) * 1993-01-08 1994-08-31 Pliva Pharm & Chem Works 9-deoxo-9a-aza-11-deoxy-9a-homoeritromycin a 9a, 11-cyclic carbamates
FR2702480B1 (fr) * 1993-03-09 1995-04-28 Roussel Uclaf Nouveaux dérivés de l'érythromycine, leur procédé de préparation et leur application comme médicaments.

Also Published As

Publication number Publication date
PT676409E (pt) 2003-08-29
AU684939B2 (en) 1998-01-08
EE9500080A (et) 1996-12-16
CN1059445C (zh) 2000-12-13
IL112954A (en) 2000-07-16
SI0676409T1 (en) 2003-06-30
LV11182A (lv) 1996-04-20
OA10200A (fr) 1996-12-18
GB2288174A (en) 1995-10-11
FR2718450B1 (fr) 1997-01-10
FR2718450A1 (fr) 1995-10-13
BR9506147A (pt) 1996-04-16
IS1865B (is) 2003-05-02
LV11182B (en) 1997-04-20
HRP950217A2 (en) 1997-08-31
MD663G2 (ro) 1997-07-31
DZ1869A1 (fr) 2002-02-17
YU49221B (sh) 2004-11-25
ATE234853T1 (de) 2003-04-15
HUT73772A (en) 1996-09-30
HRP950217B1 (en) 2004-06-30
EP0676409B1 (fr) 2003-03-19
JO1850B1 (en) 1995-12-27
CZ322395A3 (en) 1996-08-14
SK154695A3 (en) 1996-10-02
FI955913A (fi) 1995-12-08
CA2164638C (fr) 2003-12-30
MD663F1 (ro) 1997-01-31
FI955913A0 (fi) 1995-12-08
PL180837B1 (pl) 2001-04-30
AP9500743A0 (en) 1995-07-31
ES2189820T3 (es) 2003-07-16
MA23501A1 (fr) 1995-12-31
SA97170757A (ar) 2005-12-03
IS4309A (is) 1995-11-17
AP587A (en) 1997-04-29
JP3000023B2 (ja) 2000-01-17
FI111264B (fi) 2003-06-30
UA44705C2 (uk) 2002-03-15
HU9503505D0 (en) 1996-02-28
KR100317148B1 (ko) 2002-06-22
AU2310795A (en) 1995-10-30
NZ284498A (en) 1997-07-27
CA2164638A1 (fr) 1995-10-19
YU21695A (sh) 1997-12-05
US5760233A (en) 1998-06-02
NO954942L (no) 1996-02-07
GEP19991836B (en) 1999-11-05
TW316908B (no) 1997-10-01
MY114672A (en) 2002-12-31
SK284079B6 (sk) 2004-09-08
TNSN95026A1 (fr) 1996-02-06
CN1126997A (zh) 1996-07-17
JPH07278177A (ja) 1995-10-24
DK0676409T3 (da) 2003-06-23
CO4370097A1 (es) 1996-10-07
DE69529934D1 (de) 2003-04-24
EE04498B1 (et) 2005-06-15
NO954942D0 (no) 1995-12-06
EP0676409A1 (fr) 1995-10-11
GB9506856D0 (en) 1995-05-24
US5656607A (en) 1997-08-12
PE2896A1 (es) 1996-02-12
DE69529934T2 (de) 2003-09-04
HU215396B (hu) 1998-12-28
IL112954A0 (en) 1995-06-29
BG61916B1 (bg) 1998-09-30
RU2141965C1 (ru) 1999-11-27
NO308361B1 (no) 2000-09-04
PL311871A1 (en) 1996-03-18
BG100150A (bg) 1996-06-28
SV1995000018A (es) 1997-10-24
RO115634B1 (ro) 2000-04-28
CZ296005B6 (cs) 2005-12-14
WO1995027720A1 (fr) 1995-10-19

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