NO20011503D0 - Indeno-, nafto- og benzocyklohepta-dihydrotiazolderivater, deres fremstilling og anvendelse som anorektiske legemidler - Google Patents
Indeno-, nafto- og benzocyklohepta-dihydrotiazolderivater, deres fremstilling og anvendelse som anorektiske legemidlerInfo
- Publication number
- NO20011503D0 NO20011503D0 NO20011503A NO20011503A NO20011503D0 NO 20011503 D0 NO20011503 D0 NO 20011503D0 NO 20011503 A NO20011503 A NO 20011503A NO 20011503 A NO20011503 A NO 20011503A NO 20011503 D0 NO20011503 D0 NO 20011503D0
- Authority
- NO
- Norway
- Prior art keywords
- dihydrotiazole
- benzocyclohepta
- indeno
- naphtho
- derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19844547A DE19844547C2 (de) | 1998-09-29 | 1998-09-29 | Polycyclische Dihydrothiazole, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel |
PCT/EP1999/006860 WO2000018749A1 (de) | 1998-09-29 | 1999-09-16 | Indeno-, naphtho- und benzocyclohepta-dihydrothiazol derivate, deren herstellung und deren verwendung als anorektische arzneimittel |
Publications (3)
Publication Number | Publication Date |
---|---|
NO20011503L NO20011503L (no) | 2001-03-23 |
NO20011503D0 true NO20011503D0 (no) | 2001-03-23 |
NO318388B1 NO318388B1 (no) | 2005-03-14 |
Family
ID=7882588
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20011503A NO318388B1 (no) | 1998-09-29 | 2001-03-23 | Indano-dihydrotiazolderivater, deres anvendelse, legemidler omfattende disse og en fremgangsmate for fremstillimg av legemidlene. |
Country Status (25)
Country | Link |
---|---|
US (2) | US6090833A (no) |
EP (1) | EP1119557B1 (no) |
JP (1) | JP3542078B2 (no) |
KR (1) | KR20010079952A (no) |
CN (1) | CN1143852C (no) |
AR (1) | AR020662A1 (no) |
AT (1) | ATE255569T1 (no) |
AU (1) | AU755158B2 (no) |
BR (1) | BR9915014A (no) |
CA (1) | CA2345359A1 (no) |
DE (2) | DE19844547C2 (no) |
DK (1) | DK1119557T3 (no) |
ES (1) | ES2212673T3 (no) |
HK (1) | HK1040080B (no) |
HU (1) | HUP0103504A3 (no) |
ID (1) | ID29578A (no) |
IL (1) | IL142096A0 (no) |
NO (1) | NO318388B1 (no) |
NZ (1) | NZ510399A (no) |
PL (1) | PL347072A1 (no) |
PT (1) | PT1119557E (no) |
RU (1) | RU2217427C2 (no) |
TR (1) | TR200100868T2 (no) |
WO (1) | WO2000018749A1 (no) |
ZA (1) | ZA200102446B (no) |
Families Citing this family (32)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE19908539A1 (de) * | 1999-02-26 | 2000-08-31 | Aventis Pharma Gmbh | Polycyclische 2-Amino-Dihydrothiazolsysteme, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel |
IL149400A0 (en) | 1999-11-05 | 2002-11-10 | Aventis Pharma Gmbh | Indeno-, naphtho-, and benzocyclohepta-dihydrothiazole derivatives, the production thereof and their use as anorectic medicaments |
DE10008274A1 (de) * | 2000-02-23 | 2001-08-30 | Aventis Pharma Gmbh | Substituierte 8,8a-Dihydro-3aH-indeno[1,2-d]thiazole, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel |
EP1259498B1 (de) | 2000-02-23 | 2004-11-24 | Aventis Pharma Deutschland GmbH | 8,8a-dihydro-indeno [1,2-d]thiazol-derivate, die in 8a-stellung substituiert sind, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel z.b. als anorektika |
PT1261593E (pt) * | 2000-02-26 | 2004-01-30 | Aventis Pharma Gmbh | Derivados de 8,8a-di-hidro-ideno¬1,2-d|tiazole que possuem na posicao 2 um substituinte com uma estrutura de sulfona; procedimentos para a sua sintese e a sua utilizacao como farmacos |
DE10142665B4 (de) * | 2001-08-31 | 2004-05-06 | Aventis Pharma Deutschland Gmbh | C2-Disubstituierte Indan-1-one und ihre Derivate |
DE10142663B4 (de) | 2001-08-31 | 2004-08-19 | Aventis Pharma Deutschland Gmbh | C2-Disubstituierte Indan-1-ol-Systeme |
DE10142722A1 (de) * | 2001-08-31 | 2003-03-27 | Aventis Pharma Gmbh | C2-substituierte Indan-1-one und ihre Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel |
US7772188B2 (en) | 2003-01-28 | 2010-08-10 | Ironwood Pharmaceuticals, Inc. | Methods and compositions for the treatment of gastrointestinal disorders |
EP2305352A1 (en) | 2004-04-02 | 2011-04-06 | Merck Sharp & Dohme Corp. | 5-alpha-reductase inhibitors for use in the treatment of men with metabolic and anthropometric disorders |
MEP8509A (en) | 2006-09-07 | 2011-12-20 | Combination treatment for diabetes mellitus | |
CA2963857A1 (en) | 2007-06-04 | 2008-12-11 | Ben-Gurion University Of The Negev Research And Development Authority | Tri-aryl compounds and compositions comprising the same |
US8969514B2 (en) | 2007-06-04 | 2015-03-03 | Synergy Pharmaceuticals, Inc. | Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases |
EA020466B1 (ru) | 2007-06-04 | 2014-11-28 | Синерджи Фармасьютикалз Инк. | Агонисты гуанилатциклазы, пригодные для лечения желудочно-кишечных нарушений, воспаления, рака и других заболеваний |
JP2011522828A (ja) | 2008-06-04 | 2011-08-04 | シナジー ファーマシューティカルズ インコーポレイテッド | 胃腸障害、炎症、癌、およびその他の障害の治療のために有用なグアニル酸シクラーゼのアゴニスト |
CA2730603C (en) | 2008-07-16 | 2019-09-24 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders |
US8410284B2 (en) | 2008-10-22 | 2013-04-02 | Merck Sharp & Dohme Corp | Cyclic benzimidazole derivatives useful as anti-diabetic agents |
CA2741672A1 (en) | 2008-10-31 | 2010-05-06 | Merck Sharp & Dohme Corp. | Novel cyclic benzimidazole derivatives useful anti-diabetic agents |
EP2538784B1 (en) | 2010-02-25 | 2015-09-09 | Merck Sharp & Dohme Corp. | Benzimidazole derivatives useful anti-diabetic agents |
US9616097B2 (en) | 2010-09-15 | 2017-04-11 | Synergy Pharmaceuticals, Inc. | Formulations of guanylate cyclase C agonists and methods of use |
EP2677869B1 (en) | 2011-02-25 | 2017-11-08 | Merck Sharp & Dohme Corp. | Novel cyclic azabenzimidazole derivatives useful as anti-diabetic agents |
CA2828346C (en) | 2011-03-01 | 2021-01-26 | Synergy Pharmaceuticals Inc. | Process of preparing guanylate cyclase c agonists |
JP2015525782A (ja) | 2012-08-02 | 2015-09-07 | メルク・シャープ・アンド・ドーム・コーポレーションMerck Sharp & Dohme Corp. | 抗糖尿病性三環式化合物 |
CN104994848A (zh) | 2013-02-22 | 2015-10-21 | 默沙东公司 | 抗糖尿病二环化合物 |
WO2014139388A1 (en) | 2013-03-14 | 2014-09-18 | Merck Sharp & Dohme Corp. | Novel indole derivatives useful as anti-diabetic agents |
AU2014235215A1 (en) | 2013-03-15 | 2015-10-01 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase and their uses |
JP2016514670A (ja) | 2013-03-15 | 2016-05-23 | シナジー ファーマシューティカルズ インコーポレイテッド | 他の薬物と組み合わせたグアニル酸シクラーゼ受容体アゴニスト |
KR102272746B1 (ko) | 2013-06-05 | 2021-07-08 | 보슈 헬스 아일랜드 리미티드 | 구아닐레이트 사이클라제 c의 초순수 작용제, 및 이의 제조 및 사용 방법 |
WO2015051496A1 (en) | 2013-10-08 | 2015-04-16 | Merck Sharp & Dohme Corp. | Antidiabetic tricyclic compounds |
KR20160094956A (ko) | 2013-11-05 | 2016-08-10 | 벤-구리온 유니버시티 오브 더 네게브 리서치 앤드 디벨럽먼트 어쏘러티 | 당뇨병 및 당뇨병으로부터 발생하는 합병증 질환의 치료를 위한 화합물 |
WO2018106518A1 (en) | 2016-12-06 | 2018-06-14 | Merck Sharp & Dohme Corp. | Antidiabetic heterocyclic compounds |
US10968232B2 (en) | 2016-12-20 | 2021-04-06 | Merck Sharp & Dohme Corp. | Antidiabetic spirochroman compounds |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2942003A (en) * | 1957-06-06 | 1960-06-21 | Gen Aniline & Film Corp | Process for preparing naphtho [1, 2-d]-thiazoles |
DE2640358A1 (de) * | 1976-09-08 | 1978-03-16 | Hoechst Ag | Thiazolidinderivate und verfahren zu ihrer herstellung |
JPH0514068A (ja) * | 1991-07-03 | 1993-01-22 | Shimada Phys & Chem Ind Co Ltd | 並列増幅部切換型高周波低雑音増幅装置 |
JP3197602B2 (ja) * | 1992-02-17 | 2001-08-13 | 久光製薬株式会社 | チアゾール類縁化合物及び皮膚外用剤 |
KR970701705A (ko) * | 1994-03-11 | 1997-04-12 | 오노다 마사요시 | 5-HT₃ 수용체 효능제, 신규한 티아졸 유도체 및 이의 중간체(5-HT₃receptor agonist, novel thiazole derivative, and intermediate therefor) |
GB9517381D0 (en) * | 1995-08-24 | 1995-10-25 | Pharmacia Spa | Aryl and heteroaryl piperazine derivatives |
TW416953B (en) * | 1996-09-25 | 2001-01-01 | Takeda Chemical Industries Ltd | Tricyclic compounds for eliciting a prostaglandin I2 receptor agonistic effect, their production and use |
-
1998
- 1998-09-29 DE DE19844547A patent/DE19844547C2/de not_active Expired - Fee Related
-
1999
- 1999-09-16 WO PCT/EP1999/006860 patent/WO2000018749A1/de not_active Application Discontinuation
- 1999-09-16 HU HU0103504A patent/HUP0103504A3/hu unknown
- 1999-09-16 CA CA002345359A patent/CA2345359A1/en not_active Abandoned
- 1999-09-16 DK DK99969717T patent/DK1119557T3/da active
- 1999-09-16 JP JP2000572209A patent/JP3542078B2/ja not_active Expired - Fee Related
- 1999-09-16 PL PL99347072A patent/PL347072A1/xx not_active Application Discontinuation
- 1999-09-16 KR KR1020017004010A patent/KR20010079952A/ko active IP Right Grant
- 1999-09-16 TR TR2001/00868T patent/TR200100868T2/xx unknown
- 1999-09-16 IL IL14209699A patent/IL142096A0/xx not_active IP Right Cessation
- 1999-09-16 PT PT99969717T patent/PT1119557E/pt unknown
- 1999-09-16 EP EP99969717A patent/EP1119557B1/de not_active Expired - Lifetime
- 1999-09-16 AT AT99969717T patent/ATE255569T1/de not_active IP Right Cessation
- 1999-09-16 RU RU2001111750/04A patent/RU2217427C2/ru not_active IP Right Cessation
- 1999-09-16 BR BR9915014-0A patent/BR9915014A/pt not_active IP Right Cessation
- 1999-09-16 AU AU59787/99A patent/AU755158B2/en not_active Ceased
- 1999-09-16 ES ES99969717T patent/ES2212673T3/es not_active Expired - Lifetime
- 1999-09-16 CN CNB998114820A patent/CN1143852C/zh not_active Expired - Fee Related
- 1999-09-16 ID IDW20010719A patent/ID29578A/id unknown
- 1999-09-16 DE DE59907961T patent/DE59907961D1/de not_active Expired - Lifetime
- 1999-09-16 NZ NZ510399A patent/NZ510399A/en unknown
- 1999-09-27 AR ARP990104867A patent/AR020662A1/es unknown
- 1999-09-29 US US09/406,855 patent/US6090833A/en not_active Expired - Lifetime
-
2000
- 2000-06-27 US US09/604,666 patent/US6291486B1/en not_active Expired - Lifetime
-
2001
- 2001-03-23 NO NO20011503A patent/NO318388B1/no unknown
- 2001-03-26 ZA ZA200102446A patent/ZA200102446B/en unknown
-
2002
- 2002-03-01 HK HK02101580.2A patent/HK1040080B/zh not_active IP Right Cessation
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
NO20011503L (no) | Indeno-, nafto- og benzocyklohepta-dihydrotiazolderivater, deres fremstilling og anvendelse som anorektiske legemidler | |
DK1083171T3 (da) | Pyrazolinderivater, deres fremstilling og anvendelse som medikamenter | |
NO20005146D0 (no) | Tienylazolylalkoksyetanaminer, deres fremstilling og deres anvendelse som medikamenter | |
DK1095025T3 (da) | Benzimidazoler, deres fremstilling og deres anvendelse som lægemidler | |
NO991815D0 (no) | Oksadiazoler, fremgangsmÕter for deres fremstilling og deres anvendelse som medikamenter | |
NO20035298D0 (no) | CDK-inhiberende pyrimider, deres fremstilling og deres anvendelse som legemidler | |
NO993003D0 (no) | Sulfonamid-derivater, fremgangsmÕte for deres fremstilling og deres anvendelse som medikamenter | |
NO20021719L (no) | 6-posisjon substituerte indoliner, fremstilling og anvendelse derav som medikament | |
NO20006138D0 (no) | Substituerte indolinoner, fremstilling og anvendelse derav som medikamenter | |
NO20012567D0 (no) | Azepinoindolderivater, fremstilling og anvendelse derav | |
DK0966454T3 (da) | Disubstituerede bicykliske heterocykler, deres fremstilling og deres anvendelse som lægemidler | |
NO20015156L (no) | 5-pyridyl-1,3-azolforbindelser, deres fremstilling og anvendelse | |
NO20014702D0 (no) | Diarylderivater og deres anvendelse som medikamenter | |
NO20014603L (no) | Tienopyrimidinforbindelser, deres fremstilling og anvendelse | |
DK1445252T3 (da) | Sulfonamid-derivater, deres fremstilling og anvendelse som medikamenter | |
DK1230230T3 (da) | Derivater af indeno-dihydrothiazol, fremstilling deraf og anvendelse som anorektiske lægemidler | |
DK1161434T3 (da) | Pyridopyranoazepinderivater, deres fremstilling og terapeutiske anvendelse | |
DK1004592T3 (da) | Nye erythromycinderivater, deres fremstilling og deres anvendelse som medikamenter | |
NO20003773D0 (no) | Syklobutenderivater, deres fremstilling og deres terapeutiske anvendelser | |
DK1043307T3 (da) | 3-amino-3-arylpropan-1-ol-derivater, deres fremstilling og anvendelse | |
NO20000066D0 (no) | 6-pyrrolidin-2-ylpyrindin-derivater, deres fremstilling og deres farmasoeytiske anvendelse | |
DK1373249T3 (da) | Imidazolidinderivater, deres fremstilling og deres anvendelse som anti-inflammatorisk middel | |
NO20001782L (no) | 3-amino-3-arylpropan-1-ol-derivater, deres fremstilling og anvendelse | |
NO20015617L (no) | Spiroimidazolderivater, deres fremstilling, deres anvendelse og farmasöytiske preparater som innbefatter slike derivater | |
DK1235809T3 (da) | Substituerede 1,2,3,4,5,6-hexahydro-2,6-methano-3-benzazociner og deres anvendelse som lægemidler |