TR200100868T2 - Indeno-,nafto-, benzosiklohepta-dihidrotiyazol türevleri, imalatları, anorektal ilaç olarak kullanılmaları. - Google Patents
Indeno-,nafto-, benzosiklohepta-dihidrotiyazol türevleri, imalatları, anorektal ilaç olarak kullanılmaları.Info
- Publication number
- TR200100868T2 TR200100868T2 TR2001/00868T TR200100868T TR200100868T2 TR 200100868 T2 TR200100868 T2 TR 200100868T2 TR 2001/00868 T TR2001/00868 T TR 2001/00868T TR 200100868 T TR200100868 T TR 200100868T TR 200100868 T2 TR200100868 T2 TR 200100868T2
- Authority
- TR
- Turkey
- Prior art keywords
- manufacture
- benzocyclohepta
- indeno
- naphtho
- derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Diabetes (AREA)
- Obesity (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Hematology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Child & Adolescent Psychology (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Indole Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Polisiklik dihidrotiyazoller, imal edilmelerine yönelik yöntem ve ilaç maddesi olarak kullanimlari. Bulus polisiklik dihidrotiyazoller ve ayrica onlarin fizyolojik olarak hazmedilebilen tuzlari ve fizyolojik islevleri olan türevleri. Formül 1'in (FORMÜL VAR) içerisindeki artiklarin belirtilmis olan anlamlara geldigi, ve ayrica onlarin fizyolojik olarak hazmedilebilen tuzlari ve onlarin imal edilmesine yönelik yöntem tanimlanmaktadir. Bilesimler örnegin anorektikler olarak birebirdirler.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19844547A DE19844547C2 (de) | 1998-09-29 | 1998-09-29 | Polycyclische Dihydrothiazole, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel |
Publications (1)
Publication Number | Publication Date |
---|---|
TR200100868T2 true TR200100868T2 (tr) | 2001-09-21 |
Family
ID=7882588
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
TR2001/00868T TR200100868T2 (tr) | 1998-09-29 | 1999-09-16 | Indeno-,nafto-, benzosiklohepta-dihidrotiyazol türevleri, imalatları, anorektal ilaç olarak kullanılmaları. |
Country Status (25)
Country | Link |
---|---|
US (2) | US6090833A (tr) |
EP (1) | EP1119557B1 (tr) |
JP (1) | JP3542078B2 (tr) |
KR (1) | KR20010079952A (tr) |
CN (1) | CN1143852C (tr) |
AR (1) | AR020662A1 (tr) |
AT (1) | ATE255569T1 (tr) |
AU (1) | AU755158B2 (tr) |
BR (1) | BR9915014A (tr) |
CA (1) | CA2345359A1 (tr) |
DE (2) | DE19844547C2 (tr) |
DK (1) | DK1119557T3 (tr) |
ES (1) | ES2212673T3 (tr) |
HK (1) | HK1040080B (tr) |
HU (1) | HUP0103504A3 (tr) |
ID (1) | ID29578A (tr) |
IL (1) | IL142096A0 (tr) |
NO (1) | NO318388B1 (tr) |
NZ (1) | NZ510399A (tr) |
PL (1) | PL347072A1 (tr) |
PT (1) | PT1119557E (tr) |
RU (1) | RU2217427C2 (tr) |
TR (1) | TR200100868T2 (tr) |
WO (1) | WO2000018749A1 (tr) |
ZA (1) | ZA200102446B (tr) |
Families Citing this family (32)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE19908539A1 (de) * | 1999-02-26 | 2000-08-31 | Aventis Pharma Gmbh | Polycyclische 2-Amino-Dihydrothiazolsysteme, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel |
CA2389703A1 (en) * | 1999-11-05 | 2001-05-10 | Aventis Pharma Deutschland Gmbh | Indeno-, naphtho-, and benzocyclohepta-dihydrothiazole derivatives, the production thereof and their use as anorectic medicaments |
PL357547A1 (en) | 2000-02-23 | 2004-07-26 | Aventis Pharma Deutschland Gmbh | 8,8a-dihydro-indeno[1,2-d]thiazole derivatives, substituted in position 8a, a method for their production and their use as medicaments, e.g. anorectic agents |
DE10008274A1 (de) | 2000-02-23 | 2001-08-30 | Aventis Pharma Gmbh | Substituierte 8,8a-Dihydro-3aH-indeno[1,2-d]thiazole, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel |
EE04963B1 (et) * | 2000-02-26 | 2008-02-15 | Aventis Pharma Deutschland Gmbh | 8,8a-dihdroindeno[1,2-d]tiasooli derivaadid, mille 2-asendis on sulfoonamido- v?i sulfonorhma sisaldav asendaja, nende valmistamismeetod ja kasutamine ravimitena |
DE10142665B4 (de) * | 2001-08-31 | 2004-05-06 | Aventis Pharma Deutschland Gmbh | C2-Disubstituierte Indan-1-one und ihre Derivate |
DE10142722A1 (de) * | 2001-08-31 | 2003-03-27 | Aventis Pharma Gmbh | C2-substituierte Indan-1-one und ihre Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel |
DE10142663B4 (de) * | 2001-08-31 | 2004-08-19 | Aventis Pharma Deutschland Gmbh | C2-Disubstituierte Indan-1-ol-Systeme |
US7772188B2 (en) | 2003-01-28 | 2010-08-10 | Ironwood Pharmaceuticals, Inc. | Methods and compositions for the treatment of gastrointestinal disorders |
US20080125403A1 (en) | 2004-04-02 | 2008-05-29 | Merck & Co., Inc. | Method of Treating Men with Metabolic and Anthropometric Disorders |
BRPI0716134A2 (pt) | 2006-09-07 | 2013-09-17 | Nycomed Gmbh | tratamento de combinaÇço para diabetes mellitus |
MX2009013354A (es) | 2007-06-04 | 2010-07-06 | Univ Ben Gurion | Compuestos de triarilo y composiciones que los contienen. |
WO2008151257A2 (en) | 2007-06-04 | 2008-12-11 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders |
US8969514B2 (en) | 2007-06-04 | 2015-03-03 | Synergy Pharmaceuticals, Inc. | Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases |
EP2328910B1 (en) | 2008-06-04 | 2014-08-06 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders |
AU2009270833B2 (en) | 2008-07-16 | 2015-02-19 | Bausch Health Ireland Limited | Agonists of guanylate cyclase useful for the treatment of gastrointestinal, inflammation, cancer and other disorders |
CA2741125A1 (en) | 2008-10-22 | 2010-04-29 | Merck Sharp & Dohme Corp. | Novel cyclic benzimidazole derivatives useful anti-diabetic agents |
WO2010051206A1 (en) | 2008-10-31 | 2010-05-06 | Merck Sharp & Dohme Corp. | Novel cyclic benzimidazole derivatives useful anti-diabetic agents |
CA2786314A1 (en) | 2010-02-25 | 2011-09-01 | Merck Sharp & Dohme Corp. | Novel cyclic benzimidazole derivatives useful anti-diabetic agents |
US9616097B2 (en) | 2010-09-15 | 2017-04-11 | Synergy Pharmaceuticals, Inc. | Formulations of guanylate cyclase C agonists and methods of use |
PE20140859A1 (es) | 2011-02-25 | 2014-07-25 | Merck Sharp & Dohme | Novedosos derivados de azabencimidazol ciclico utiles como agentes antidiabeticos |
CA3100941C (en) | 2011-03-01 | 2024-03-05 | Synergy Pharmaceuticals Inc. | Process of preparing guanylate cyclase c agonists |
BR112015002080A2 (pt) | 2012-08-02 | 2017-07-04 | Merck Sharp & Dohme | composto, composição farmacêutica, uso de um composto, e, método de tratamento ou de prevenção de um transtorno, de uma condição ou de uma doença |
EP2958562A4 (en) | 2013-02-22 | 2016-08-10 | Merck Sharp & Dohme | BICYCLIC ANTIDIABETIC COMPOUNDS |
US9650375B2 (en) | 2013-03-14 | 2017-05-16 | Merck Sharp & Dohme Corp. | Indole derivatives useful as anti-diabetic agents |
CA2905438A1 (en) | 2013-03-15 | 2014-09-25 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase and their uses |
EP2968439A2 (en) | 2013-03-15 | 2016-01-20 | Synergy Pharmaceuticals Inc. | Compositions useful for the treatment of gastrointestinal disorders |
US10011637B2 (en) | 2013-06-05 | 2018-07-03 | Synergy Pharmaceuticals, Inc. | Ultra-pure agonists of guanylate cyclase C, method of making and using same |
WO2015051496A1 (en) | 2013-10-08 | 2015-04-16 | Merck Sharp & Dohme Corp. | Antidiabetic tricyclic compounds |
AU2014347668A1 (en) | 2013-11-05 | 2016-05-19 | Ben-Gurion University Of The Negev Research And Development Authority | Compounds for the treatment of diabetes and disease complications arising from same |
EP3551176A4 (en) | 2016-12-06 | 2020-06-24 | Merck Sharp & Dohme Corp. | ANTIDIABETIC HETEROCYCLIC COMPOUNDS |
WO2018118670A1 (en) | 2016-12-20 | 2018-06-28 | Merck Sharp & Dohme Corp. | Antidiabetic spirochroman compounds |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2942003A (en) * | 1957-06-06 | 1960-06-21 | Gen Aniline & Film Corp | Process for preparing naphtho [1, 2-d]-thiazoles |
DE2640358A1 (de) * | 1976-09-08 | 1978-03-16 | Hoechst Ag | Thiazolidinderivate und verfahren zu ihrer herstellung |
JPH0514068A (ja) * | 1991-07-03 | 1993-01-22 | Shimada Phys & Chem Ind Co Ltd | 並列増幅部切換型高周波低雑音増幅装置 |
JP3197602B2 (ja) * | 1992-02-17 | 2001-08-13 | 久光製薬株式会社 | チアゾール類縁化合物及び皮膚外用剤 |
MX9603998A (es) * | 1994-03-11 | 1997-12-31 | Yamanouchi Pharma Co Ltd | Agonista receptor de 5-ht3, derivado de tiazol novedoso e intermediario del mismo. |
GB9517381D0 (en) * | 1995-08-24 | 1995-10-25 | Pharmacia Spa | Aryl and heteroaryl piperazine derivatives |
TW416953B (en) * | 1996-09-25 | 2001-01-01 | Takeda Chemical Industries Ltd | Tricyclic compounds for eliciting a prostaglandin I2 receptor agonistic effect, their production and use |
-
1998
- 1998-09-29 DE DE19844547A patent/DE19844547C2/de not_active Expired - Fee Related
-
1999
- 1999-09-16 EP EP99969717A patent/EP1119557B1/de not_active Expired - Lifetime
- 1999-09-16 RU RU2001111750/04A patent/RU2217427C2/ru not_active IP Right Cessation
- 1999-09-16 JP JP2000572209A patent/JP3542078B2/ja not_active Expired - Fee Related
- 1999-09-16 PT PT99969717T patent/PT1119557E/pt unknown
- 1999-09-16 NZ NZ510399A patent/NZ510399A/en unknown
- 1999-09-16 HU HU0103504A patent/HUP0103504A3/hu unknown
- 1999-09-16 ID IDW20010719A patent/ID29578A/id unknown
- 1999-09-16 PL PL99347072A patent/PL347072A1/xx not_active Application Discontinuation
- 1999-09-16 IL IL14209699A patent/IL142096A0/xx not_active IP Right Cessation
- 1999-09-16 TR TR2001/00868T patent/TR200100868T2/tr unknown
- 1999-09-16 CN CNB998114820A patent/CN1143852C/zh not_active Expired - Fee Related
- 1999-09-16 DK DK99969717T patent/DK1119557T3/da active
- 1999-09-16 DE DE59907961T patent/DE59907961D1/de not_active Expired - Lifetime
- 1999-09-16 AU AU59787/99A patent/AU755158B2/en not_active Ceased
- 1999-09-16 KR KR1020017004010A patent/KR20010079952A/ko active IP Right Grant
- 1999-09-16 WO PCT/EP1999/006860 patent/WO2000018749A1/de not_active Application Discontinuation
- 1999-09-16 AT AT99969717T patent/ATE255569T1/de not_active IP Right Cessation
- 1999-09-16 BR BR9915014-0A patent/BR9915014A/pt not_active IP Right Cessation
- 1999-09-16 ES ES99969717T patent/ES2212673T3/es not_active Expired - Lifetime
- 1999-09-16 CA CA002345359A patent/CA2345359A1/en not_active Abandoned
- 1999-09-27 AR ARP990104867A patent/AR020662A1/es unknown
- 1999-09-29 US US09/406,855 patent/US6090833A/en not_active Expired - Lifetime
-
2000
- 2000-06-27 US US09/604,666 patent/US6291486B1/en not_active Expired - Lifetime
-
2001
- 2001-03-23 NO NO20011503A patent/NO318388B1/no unknown
- 2001-03-26 ZA ZA200102446A patent/ZA200102446B/en unknown
-
2002
- 2002-03-01 HK HK02101580.2A patent/HK1040080B/zh not_active IP Right Cessation
Also Published As
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