WO2005028434A2 - Novel heterocyclic compounds as hsp90-inhibitors - Google Patents
Novel heterocyclic compounds as hsp90-inhibitors Download PDFInfo
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- WO2005028434A2 WO2005028434A2 PCT/US2004/031248 US2004031248W WO2005028434A2 WO 2005028434 A2 WO2005028434 A2 WO 2005028434A2 US 2004031248 W US2004031248 W US 2004031248W WO 2005028434 A2 WO2005028434 A2 WO 2005028434A2
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- WIPO (PCT)
- Prior art keywords
- compound
- aryl
- heteroaryl
- group
- tautomer
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Classifications
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- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
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- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
- C07D473/18—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 one oxygen and one nitrogen atom, e.g. guanine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
- C07D473/24—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 one nitrogen and one sulfur atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
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Landscapes
- Health & Medical Sciences (AREA)
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- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Priority Applications (12)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| NZ546611A NZ546611A (en) | 2003-09-18 | 2004-09-20 | Novel heterocyclic compounds as HSP90-inhibitors |
| MXPA06002997A MXPA06002997A (es) | 2003-09-18 | 2004-09-20 | Novedosos compuestos heterociclicos como inhibidores- hsp90. |
| CA002539548A CA2539548A1 (en) | 2003-09-18 | 2004-09-20 | Novel heterocyclic compounds as hsp90-inhibitors |
| JP2006527162A JP2007505933A (ja) | 2003-09-18 | 2004-09-20 | Ｈｓｐ９０インヒビターとしての新規なヘテロ環化合物 |
| EP04788954A EP1670802A4 (en) | 2003-09-18 | 2004-09-20 | NOVEL HETEROCYCLIC COMPOUNDS AS INHIBITORS OF HSP90 PROTEIN |
| BRPI0414533-0A BRPI0414533A (pt) | 2003-09-18 | 2004-09-20 | composto, composição farmacêutica, e, métodos para inibir um hsp90 e para tratar um indivìduo tendo um distúrbio mediado por hsp90 |
| AU2004274507A AU2004274507B2 (en) | 2003-09-18 | 2004-09-20 | Novel heterocyclic compounds as HSP90-inhibitors |
| EA200600594A EA010160B1 (ru) | 2003-09-18 | 2004-09-20 | Новые гетероциклические соединения - ингибиторы hsp90 и способы их получения |
| CN2004800335230A CN1882589B (zh) | 2003-09-18 | 2004-09-20 | 作为hsp90-抑制剂的新的杂环化合物 |
| IL174375A IL174375A0 (en) | 2003-09-18 | 2006-03-16 | Novel heterocyclic compounds as hsp90-inhibitors |
| NO20061396A NO20061396L (no) | 2003-09-18 | 2006-03-27 | Nye heterocykliske forbindelser som HSP90-inhibitorer |
| AU2010202750A AU2010202750B2 (en) | 2003-09-18 | 2010-06-30 | Novel heterocyclic compounds as HSP90-inhibitors |
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| PCT/US2004/031248 WO2005028434A2 (en) | 2003-09-18 | 2004-09-20 | Novel heterocyclic compounds as hsp90-inhibitors |
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Also Published As
| Publication number | Publication date |
|---|---|
| AU2010202750B2 (en) | 2011-09-01 |
| NZ546611A (en) | 2010-02-26 |
| EA010160B1 (ru) | 2008-06-30 |
| IL174375A0 (en) | 2006-08-01 |
| CN101906106A (zh) | 2010-12-08 |
| US20070111996A1 (en) | 2007-05-17 |
| AU2004274507B2 (en) | 2010-08-19 |
| US20050113339A1 (en) | 2005-05-26 |
| AU2010202750A1 (en) | 2010-07-22 |
| US20050113340A1 (en) | 2005-05-26 |
| US7148228B2 (en) | 2006-12-12 |
| CA2539548A1 (en) | 2005-03-31 |
| US20050119282A1 (en) | 2005-06-02 |
| US7138401B2 (en) | 2006-11-21 |
| US7129244B2 (en) | 2006-10-31 |
| US20050107343A1 (en) | 2005-05-19 |
| EP1670802A2 (en) | 2006-06-21 |
| NO20061396L (no) | 2006-06-16 |
| US20070185064A1 (en) | 2007-08-09 |
| MXPA06002997A (es) | 2007-02-08 |
| US20070173483A1 (en) | 2007-07-26 |
| WO2005028434A3 (en) | 2006-03-23 |
| JP2007505933A (ja) | 2007-03-15 |
| KR20060070572A (ko) | 2006-06-23 |
| US7138402B2 (en) | 2006-11-21 |
| US20070111997A1 (en) | 2007-05-17 |
| BRPI0414533A (pt) | 2006-11-07 |
| EP1670802A4 (en) | 2010-07-07 |
| EA200600594A1 (ru) | 2006-10-27 |
| AU2004274507A1 (en) | 2005-03-31 |
| EP2145888A1 (en) | 2010-01-20 |
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