SE8801729D0 - Purine derivatives for use in therapy - Google Patents

Purine derivatives for use in therapy

Info

Publication number
SE8801729D0
SE8801729D0 SE8801729A SE8801729A SE8801729D0 SE 8801729 D0 SE8801729 D0 SE 8801729D0 SE 8801729 A SE8801729 A SE 8801729A SE 8801729 A SE8801729 A SE 8801729A SE 8801729 D0 SE8801729 D0 SE 8801729D0
Authority
SE
Sweden
Prior art keywords
hydroxy
amino
hydrogen
compounds
chem
Prior art date
Application number
SE8801729A
Other languages
English (en)
Inventor
B G Lindborg
R Datema
K N G Johansson
B F Oberg
Original Assignee
Astra Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astra Ab filed Critical Astra Ab
Priority to SE8801729A priority Critical patent/SE8801729D0/sv
Publication of SE8801729D0 publication Critical patent/SE8801729D0/sv
Priority to IL9016689A priority patent/IL90166A/en
Priority to NZ229002A priority patent/NZ229002A/en
Priority to MYPI89000618A priority patent/MY108541A/en
Priority to CA000598887A priority patent/CA1340909C/en
Priority to HU893004A priority patent/HU207082B/hu
Priority to PCT/SE1989/000255 priority patent/WO1989010923A1/en
Priority to US07/601,693 priority patent/US5284837A/en
Priority to JP1505738A priority patent/JP2866688B2/ja
Priority to DE8989850146T priority patent/DE68901153D1/de
Priority to IE147289A priority patent/IE62066B1/en
Priority to ES198989850146T priority patent/ES2033548T3/es
Priority to AT89850146T priority patent/ATE74603T1/de
Priority to AU35726/89A priority patent/AU626300C/en
Priority to EP89850146A priority patent/EP0343133B1/en
Priority to PT90478A priority patent/PT90478B/pt
Priority to KR90700035A priority patent/KR0141913B1/ko
Priority to DK199002649A priority patent/DK174986B1/da
Priority to FI905475A priority patent/FI98729C/sv
Priority to NO904798A priority patent/NO177306C/no
Priority to PH43233A priority patent/PH27516A/en
Priority to GR920400840T priority patent/GR3004482T3/el
Priority to US08/416,539 priority patent/US5565461A/en
Priority to US08/476,348 priority patent/US5656617A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
    • C07F9/65616—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings containing the ring system having three or more than three double bonds between ring members or between ring members and non-ring members, e.g. purine or analogs
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6564—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms
    • C07F9/6571—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and oxygen atoms as the only ring hetero atoms
    • C07F9/657163—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and oxygen atoms as the only ring hetero atoms the ring phosphorus atom being bound to at least one carbon atom
    • C07F9/657181—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and oxygen atoms as the only ring hetero atoms the ring phosphorus atom being bound to at least one carbon atom the ring phosphorus atom and, at least, one ring oxygen atom being part of a (thio)phosphonic acid derivative
SE8801729A 1988-05-06 1988-05-06 Purine derivatives for use in therapy SE8801729D0 (sv)

Priority Applications (24)

Application Number Priority Date Filing Date Title
SE8801729A SE8801729D0 (sv) 1988-05-06 1988-05-06 Purine derivatives for use in therapy
IL9016689A IL90166A (en) 1988-05-06 1989-05-03 Antiretroviral drug preparations containing a history of 9-) 2,4-Butyl di-converted (H 9-Purine such new compounds and their preparation
NZ229002A NZ229002A (en) 1988-05-06 1989-05-04 Purine derivatives and antiviral compositions
CA000598887A CA1340909C (en) 1988-05-06 1989-05-05 Purine derivatives and use thereof in therapy
IE147289A IE62066B1 (en) 1988-05-06 1989-05-05 Purine derivatives and use thereof in therapy
EP89850146A EP0343133B1 (en) 1988-05-06 1989-05-05 Derivatives of purine, process for their preparation and a pharmaceutical preparation
HU893004A HU207082B (en) 1988-05-06 1989-05-05 Process for producing purine derivatives and pharmaceutical compositions comprising same
PCT/SE1989/000255 WO1989010923A1 (en) 1988-05-06 1989-05-05 Derivatives of purine, process for their preparation and a pharmaceutical preparation
US07/601,693 US5284837A (en) 1988-05-06 1989-05-05 Derivatives of purine, process for their preparation and a pharmaceutical preparation
JP1505738A JP2866688B2 (ja) 1988-05-06 1989-05-05 プリン誘導体を含有する抗ウィルス剤
DE8989850146T DE68901153D1 (de) 1988-05-06 1989-05-05 Derivate von purin, verfahren zu ihrer herstellung und pharmazeutische zubereitung.
MYPI89000618A MY108541A (en) 1988-05-06 1989-05-05 Purine derivatives and use thereof in therapy.
ES198989850146T ES2033548T3 (es) 1988-05-06 1989-05-05 Procedimiento para la preparacion de derivados de purina.
AT89850146T ATE74603T1 (de) 1988-05-06 1989-05-05 Derivate von purin, verfahren zu ihrer herstellung und pharmazeutische zubereitung.
AU35726/89A AU626300C (en) 1988-05-06 1989-05-05 Derivatives of purine, process for their preparation and a pharmaceutical preparation
PT90478A PT90478B (pt) 1988-05-06 1989-05-15 Processo para a preparacao de derivados da purina e de composicoes farmaceuticas que os contem
KR90700035A KR0141913B1 (en) 1988-05-06 1990-01-06 Anti-virus agents
DK199002649A DK174986B1 (da) 1988-05-06 1990-11-05 Anvendelse af purinderivater til fremstilling af et lægemiddel
FI905475A FI98729C (sv) 1988-05-06 1990-11-05 Förfarande för framställning av farmaceutiskt aktiva purinderivat
NO904798A NO177306C (no) 1988-05-06 1990-11-05 Analogifremgangsmåte for fremstilling av terapautisk aktive purinderivater
PH43233A PH27516A (en) 1988-05-06 1991-10-02 Purine derivatives and use thereof in therapy
GR920400840T GR3004482T3 (sv) 1988-05-06 1992-05-05
US08/416,539 US5565461A (en) 1988-05-06 1995-04-03 Derivatives of purine, process for their preparation and a pharmaceutical preparation
US08/476,348 US5656617A (en) 1988-05-06 1995-06-07 Derivatives of purine, process for their preparation and a pharmaceutical preparation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE8801729A SE8801729D0 (sv) 1988-05-06 1988-05-06 Purine derivatives for use in therapy

Publications (1)

Publication Number Publication Date
SE8801729D0 true SE8801729D0 (sv) 1988-05-06

Family

ID=20372263

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8801729A SE8801729D0 (sv) 1988-05-06 1988-05-06 Purine derivatives for use in therapy

Country Status (18)

Country Link
EP (1) EP0343133B1 (sv)
JP (1) JP2866688B2 (sv)
KR (1) KR0141913B1 (sv)
AT (1) ATE74603T1 (sv)
CA (1) CA1340909C (sv)
DE (1) DE68901153D1 (sv)
DK (1) DK174986B1 (sv)
ES (1) ES2033548T3 (sv)
FI (1) FI98729C (sv)
GR (1) GR3004482T3 (sv)
HU (1) HU207082B (sv)
IE (1) IE62066B1 (sv)
IL (1) IL90166A (sv)
MY (1) MY108541A (sv)
NZ (1) NZ229002A (sv)
PT (1) PT90478B (sv)
SE (1) SE8801729D0 (sv)
WO (1) WO1989010923A1 (sv)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8904855D0 (en) * 1989-03-03 1989-04-12 Beecham Group Plc Pharmaceutical treatment
US6069252A (en) * 1990-02-01 2000-05-30 Emory University Method of resolution and antiviral activity of 1,3-oxathiolane nucleoside enantiomers
WO1992001698A1 (en) * 1990-07-19 1992-02-06 Beecham Group Plc Antiviral phosphono-alken derivatives of purines
GB9020932D0 (en) * 1990-09-26 1990-11-07 Wellcome Found Heterocyclic compounds
US5208221A (en) * 1990-11-29 1993-05-04 Bristol-Myers Squibb Company Antiviral (phosphonomethoxy) methoxy purine/pyrimidine derivatives
US5360714A (en) * 1992-08-28 1994-11-01 Fox Chase Cancer Center Hepadnavirus polymerase gene product having RNA-dependent DNA priming and reverse transcriptase activities and methods of measuring the activities thereof
US5334525A (en) * 1992-08-28 1994-08-02 Fox Chase Cancer Center Hepadnavirus polymerase gene product having RNA-dependent DNA priming and reverse transcriptase activities and methods of measuring the activities thereof
US5798340A (en) 1993-09-17 1998-08-25 Gilead Sciences, Inc. Nucleotide analogs
US5656745A (en) * 1993-09-17 1997-08-12 Gilead Sciences, Inc. Nucleotide analogs
CA2171868A1 (en) * 1993-09-17 1995-03-23 Petr Alexander Method for dosing therapeutic compounds
DE19540798A1 (de) * 1995-11-02 1997-05-07 Hoechst Ag Alkylxanthinphosphonate und Alkylxanthinphosphinoxide und deren Verwendung als Arzneimittel
US20030040467A1 (en) 1998-06-15 2003-02-27 Mary Ann Pelleymounter Ig/ob fusions and uses thereof.
US5717095A (en) * 1995-12-29 1998-02-10 Gilead Sciences, Inc. Nucleotide analogs
NZ325704A (en) * 1995-12-29 2000-02-28 Gilead Sciences Inc Nucleotide analogs
US5869493A (en) * 1996-02-16 1999-02-09 Medivir Ab Acyclic nucleoside derivatives
US6703394B2 (en) 1996-02-16 2004-03-09 Medivir Ab Acyclic nucleoside derivatives
DE69809205T2 (de) * 1997-02-10 2003-05-28 Medivir Ab Huddinge Verfahren zur herstellung von azyklischen nukleosiden
JP2009298785A (ja) * 1997-02-10 2009-12-24 Medivir Ab 非環状ヌクレオシド誘導体の合成
US6184376B1 (en) 1997-02-10 2001-02-06 Mediver Ab Synthesis of acyclic nucleoside derivatives
US6753322B2 (en) 2000-06-06 2004-06-22 Pfizer Inc 2-aminocarbonyl-9H-purine derivatives
US7241890B2 (en) 2001-10-30 2007-07-10 Conforma Therapeutics Corporation Purine analogs having HSP90-inhibiting activity
TWI332507B (en) 2002-11-19 2010-11-01 Hoffmann La Roche Antiviral nucleoside derivatives
US7129244B2 (en) 2003-09-18 2006-10-31 Conforma Therapeutics Corporation Triazolopyrimidines and related analogs as HSP90-inhibitors
BRPI0609509A2 (pt) 2005-03-30 2010-04-13 Conforma Therapeutics Corp composto ou um polimorfo, solvato, tautÈmero, enanciÈmero, pró-droga ou sal farmaceuticamente aceitável do mesmo, composição farmacêutica, e, uso do composto, polimorfo, solvato, tautÈmero, enanciÈmero, pró-droga ou sal farmaceuticamente aceitável
CN102171185A (zh) * 2008-08-01 2011-08-31 拜奥西尼斯医药股份有限公司 甲硫氨酸类似物及其使用方法
CN102250126A (zh) * 2010-05-18 2011-11-23 北京化工大学 一种双嘌呤类衍生物及其合成

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU573540B2 (en) * 1982-10-14 1988-06-16 Wellcome Foundation Limited, The 6-hydrogen purine derivatives
CS233665B1 (en) * 1983-01-06 1985-03-14 Antonin Holy Processing of isomere o-phosphonylmethylderivative of anantiomere racemic vicinal diene
IL73682A (en) * 1983-12-20 1991-08-16 Medivir Ab Antiviral pharmaceutical compositions containing 9-hydroxy aliphatic derivatives of guanine,some new such derivatives and process for their preparation
SE8406538D0 (sv) * 1984-12-21 1984-12-21 Astra Laekemedel Ab Novel derivatives of purine
MY101126A (en) * 1985-12-13 1991-07-31 Beecham Group Plc Novel compounds

Also Published As

Publication number Publication date
HU207082B (en) 1993-03-01
ATE74603T1 (de) 1992-04-15
NZ229002A (en) 1997-05-26
HUT57767A (en) 1991-12-30
DK264990D0 (da) 1990-11-05
KR0141913B1 (en) 1998-06-01
EP0343133B1 (en) 1992-04-08
FI98729B (sv) 1997-04-30
IL90166A (en) 1996-09-12
AU3572689A (en) 1989-11-29
GR3004482T3 (sv) 1993-03-31
IL90166A0 (en) 1989-12-15
DE68901153D1 (de) 1992-05-14
JPH03504243A (ja) 1991-09-19
DK264990A (da) 1990-11-05
DK174986B1 (da) 2004-04-13
HU893004D0 (en) 1991-09-30
JP2866688B2 (ja) 1999-03-08
EP0343133A1 (en) 1989-11-23
FI905475A0 (sv) 1990-11-05
FI98729C (sv) 1997-08-11
WO1989010923A1 (en) 1989-11-16
AU626300B2 (en) 1992-07-30
IE891472L (en) 1989-11-06
ES2033548T3 (es) 1993-03-16
PT90478B (pt) 1994-08-31
PT90478A (pt) 1989-11-30
MY108541A (en) 1996-10-31
CA1340909C (en) 2000-02-22
IE62066B1 (en) 1994-12-14

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