SE8406538D0 - Novel derivatives of purine - Google Patents

Novel derivatives of purine

Info

Publication number
SE8406538D0
SE8406538D0 SE8406538A SE8406538A SE8406538D0 SE 8406538 D0 SE8406538 D0 SE 8406538D0 SE 8406538 A SE8406538 A SE 8406538A SE 8406538 A SE8406538 A SE 8406538A SE 8406538 D0 SE8406538 D0 SE 8406538D0
Authority
SE
Sweden
Prior art keywords
sub
hydrogen
hydroxymethyl
compounds
hydroxy
Prior art date
Application number
SE8406538A
Other languages
English (en)
Inventor
K N G Johansson
Z M I Kovacs
B G Lindborg
G B Stening
Original Assignee
Astra Laekemedel Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astra Laekemedel Ab filed Critical Astra Laekemedel Ab
Priority to SE8406538A priority Critical patent/SE8406538D0/sv
Publication of SE8406538D0 publication Critical patent/SE8406538D0/sv
Priority to EP19850850398 priority patent/EP0186640B1/en
Priority to DE8585850398T priority patent/DE3575927D1/de
Priority to AT85850398T priority patent/ATE50260T1/de
Priority to JP60284503A priority patent/JPH0680061B2/ja
Priority to US07/147,051 priority patent/US5036071A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
SE8406538A 1984-12-21 1984-12-21 Novel derivatives of purine SE8406538D0 (sv)

Priority Applications (6)

Application Number Priority Date Filing Date Title
SE8406538A SE8406538D0 (sv) 1984-12-21 1984-12-21 Novel derivatives of purine
EP19850850398 EP0186640B1 (en) 1984-12-21 1985-12-13 Derivatives of purine, process for their preparation and a pharmaceutical preparation
DE8585850398T DE3575927D1 (de) 1984-12-21 1985-12-13 Purinderivate, verfahren zu ihrer herstellung und pharmazeutische zubereitung.
AT85850398T ATE50260T1 (de) 1984-12-21 1985-12-13 Purinderivate, verfahren zu ihrer herstellung und pharmazeutische zubereitung.
JP60284503A JPH0680061B2 (ja) 1984-12-21 1985-12-19 新規なプリン誘導体
US07/147,051 US5036071A (en) 1984-12-21 1988-01-22 Derivatives of purine

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE8406538A SE8406538D0 (sv) 1984-12-21 1984-12-21 Novel derivatives of purine

Publications (1)

Publication Number Publication Date
SE8406538D0 true SE8406538D0 (sv) 1984-12-21

Family

ID=20358263

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8406538A SE8406538D0 (sv) 1984-12-21 1984-12-21 Novel derivatives of purine

Country Status (6)

Country Link
US (1) US5036071A (sv)
EP (1) EP0186640B1 (sv)
JP (1) JPH0680061B2 (sv)
AT (1) ATE50260T1 (sv)
DE (1) DE3575927D1 (sv)
SE (1) SE8406538D0 (sv)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5684153A (en) 1984-08-16 1997-11-04 Beecham Group Plc Process for the preparation of purine derivatives
US5250688A (en) * 1984-09-20 1993-10-05 Beecham Group P.L.C. Purine derivatives
US4724232A (en) * 1985-03-16 1988-02-09 Burroughs Wellcome Co. Treatment of human viral infections
US5246937A (en) * 1985-09-18 1993-09-21 Beecham Group P.L.C. Purine derivatives
GB8713695D0 (en) * 1987-06-11 1987-07-15 Beecham Group Plc Process
US4965270A (en) * 1987-05-30 1990-10-23 Beecham Group P.L.C. Purine derivatives
US5284837A (en) * 1988-05-06 1994-02-08 Medivir Ab Derivatives of purine, process for their preparation and a pharmaceutical preparation
SE8801729D0 (sv) * 1988-05-06 1988-05-06 Astra Ab Purine derivatives for use in therapy
GB8829571D0 (en) * 1988-12-19 1989-02-08 Wellcome Found Antiviral compounds
CA2009109A1 (en) * 1989-02-02 1990-08-02 John Hannah Antiviral acyclonucleosides and acyclonucleotides
GB8904855D0 (en) * 1989-03-03 1989-04-12 Beecham Group Plc Pharmaceutical treatment
GB8922076D0 (en) * 1989-09-28 1989-11-15 Beecham Group Plc Novel process
KR0155168B1 (ko) * 1989-09-29 1998-11-16 미우라 아끼라 6-치환된 아시클로피리미딘 뉴클레오시드 유도체 및 이를 활성성분으로 함유하는 항비루스제
USRE37979E1 (en) * 1989-09-29 2003-02-04 Mitsubishi Chemical Corporation Pyrimidine derivatives and anti-viral agent containing the same as active ingredient thereof
US5639757A (en) * 1995-05-23 1997-06-17 Pfizer Inc. 4-aminopyrrolo[2,3-d]pyrimidines as tyrosine kinase inhibitors
DE19536164A1 (de) * 1995-09-28 1997-04-03 Boehringer Ingelheim Kg Verbessertes Verfahren zur Herstellung von 9-[(2-Hyroxyethoxy)methyl]guanin (Acyclovir)
US6703394B2 (en) 1996-02-16 2004-03-09 Medivir Ab Acyclic nucleoside derivatives
US5869493A (en) 1996-02-16 1999-02-09 Medivir Ab Acyclic nucleoside derivatives
GB9615275D0 (en) * 1996-07-20 1996-09-04 Smithkline Beecham Plc Pharmaceuticals
GR1002949B (el) * 1996-07-20 1998-07-29 Smithkline Beecham P.L.C. Φαρμακα
GB9615253D0 (en) * 1996-07-20 1996-09-04 Smithkline Beecham Plc Pharmaceuticals
GB9615276D0 (en) * 1996-07-20 1996-09-04 Smithkline Beecham Plc Pharmaceuticals
GB9807114D0 (en) 1998-04-02 1998-06-03 Smithkline Beecham Plc Novel process
US6653318B1 (en) 1999-07-21 2003-11-25 Yale University 5-(E)-Bromovinyl uracil analogues and related pyrimidine nucleosides as anti-viral agents and methods of use
US20050215787A1 (en) * 2004-03-26 2005-09-29 Joshi Ramesh A An improved process for the preparation of purines
GB2426247A (en) * 2005-05-20 2006-11-22 Arrow Int Ltd Methods of preparing purine derivatives such as famciclovir

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3891757A (en) 1971-11-11 1975-06-24 Alza Corp Anaesthetic topical and percutaneous administration with selected promoters
GB1523865A (en) * 1974-09-02 1978-09-06 Wellcome Found Purine compunds and salts thereof
US4199574A (en) 1974-09-02 1980-04-22 Burroughs Wellcome Co. Methods and compositions for treating viral infections and guanine acyclic nucleosides
US4355032B2 (en) 1981-05-21 1990-10-30 9-(1,3-dihydroxy-2-propoxymethyl)guanine as antiviral agent
NZ201662A (en) 1981-08-26 1986-07-11 Merck & Co Inc 9-(1,3-(and 2,3)-dihydroxy-1-(and 2)-propoxy-methyl)guanine derivatives and methods for their preparation
US4556659A (en) * 1982-08-09 1985-12-03 Syntex (U.S.A.) Inc. Substituted 9-(1-0- or 3-0-monosubstituted or 1,3-Di-0-substituted propoxymethyl)-purines as antiviral agents
PL143208B1 (en) * 1982-10-14 1988-01-30 Wellcome Found Method of obtaining novel 2-amino-9-/2-hydroxyetoxymethyl/purine
US4609662A (en) * 1982-10-14 1986-09-02 Burroughs Wellcome Co. Method for using purine derivatives
IL73682A (en) * 1983-12-20 1991-08-16 Medivir Ab Antiviral pharmaceutical compositions containing 9-hydroxy aliphatic derivatives of guanine,some new such derivatives and process for their preparation
EP0182024B1 (en) * 1984-09-20 1991-04-03 Beecham Group Plc Purine derivatives and their pharmaceutical use

Also Published As

Publication number Publication date
JPH0680061B2 (ja) 1994-10-12
US5036071A (en) 1991-07-30
EP0186640B1 (en) 1990-02-07
EP0186640A1 (en) 1986-07-02
ATE50260T1 (de) 1990-02-15
DE3575927D1 (de) 1990-03-15
JPS61171481A (ja) 1986-08-02

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