DE3575927D1 - Purinderivate, verfahren zu ihrer herstellung und pharmazeutische zubereitung. - Google Patents
Purinderivate, verfahren zu ihrer herstellung und pharmazeutische zubereitung.Info
- Publication number
- DE3575927D1 DE3575927D1 DE8585850398T DE3575927T DE3575927D1 DE 3575927 D1 DE3575927 D1 DE 3575927D1 DE 8585850398 T DE8585850398 T DE 8585850398T DE 3575927 T DE3575927 T DE 3575927T DE 3575927 D1 DE3575927 D1 DE 3575927D1
- Authority
- DE
- Germany
- Prior art keywords
- sub
- hydrogen
- hydroxymethyl
- compounds
- hydroxy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Virology (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Biotechnology (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE8406538A SE8406538D0 (sv) | 1984-12-21 | 1984-12-21 | Novel derivatives of purine |
Publications (1)
Publication Number | Publication Date |
---|---|
DE3575927D1 true DE3575927D1 (de) | 1990-03-15 |
Family
ID=20358263
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE8585850398T Expired - Lifetime DE3575927D1 (de) | 1984-12-21 | 1985-12-13 | Purinderivate, verfahren zu ihrer herstellung und pharmazeutische zubereitung. |
Country Status (6)
Country | Link |
---|---|
US (1) | US5036071A (de) |
EP (1) | EP0186640B1 (de) |
JP (1) | JPH0680061B2 (de) |
AT (1) | ATE50260T1 (de) |
DE (1) | DE3575927D1 (de) |
SE (1) | SE8406538D0 (de) |
Families Citing this family (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5250688A (en) * | 1984-09-20 | 1993-10-05 | Beecham Group P.L.C. | Purine derivatives |
US5684153A (en) | 1984-08-16 | 1997-11-04 | Beecham Group Plc | Process for the preparation of purine derivatives |
US4724232A (en) * | 1985-03-16 | 1988-02-09 | Burroughs Wellcome Co. | Treatment of human viral infections |
US5246937A (en) * | 1985-09-18 | 1993-09-21 | Beecham Group P.L.C. | Purine derivatives |
US4965270A (en) * | 1987-05-30 | 1990-10-23 | Beecham Group P.L.C. | Purine derivatives |
GB8713695D0 (en) * | 1987-06-11 | 1987-07-15 | Beecham Group Plc | Process |
US5284837A (en) * | 1988-05-06 | 1994-02-08 | Medivir Ab | Derivatives of purine, process for their preparation and a pharmaceutical preparation |
SE8801729D0 (sv) * | 1988-05-06 | 1988-05-06 | Astra Ab | Purine derivatives for use in therapy |
GB8829571D0 (en) * | 1988-12-19 | 1989-02-08 | Wellcome Found | Antiviral compounds |
CA2009109A1 (en) * | 1989-02-02 | 1990-08-02 | John Hannah | Antiviral acyclonucleosides and acyclonucleotides |
GB8904855D0 (en) * | 1989-03-03 | 1989-04-12 | Beecham Group Plc | Pharmaceutical treatment |
GB8922076D0 (en) * | 1989-09-28 | 1989-11-15 | Beecham Group Plc | Novel process |
KR0155168B1 (ko) * | 1989-09-29 | 1998-11-16 | 미우라 아끼라 | 6-치환된 아시클로피리미딘 뉴클레오시드 유도체 및 이를 활성성분으로 함유하는 항비루스제 |
USRE37979E1 (en) * | 1989-09-29 | 2003-02-04 | Mitsubishi Chemical Corporation | Pyrimidine derivatives and anti-viral agent containing the same as active ingredient thereof |
US5639757A (en) * | 1995-05-23 | 1997-06-17 | Pfizer Inc. | 4-aminopyrrolo[2,3-d]pyrimidines as tyrosine kinase inhibitors |
DE19536164A1 (de) * | 1995-09-28 | 1997-04-03 | Boehringer Ingelheim Kg | Verbessertes Verfahren zur Herstellung von 9-[(2-Hyroxyethoxy)methyl]guanin (Acyclovir) |
US5869493A (en) * | 1996-02-16 | 1999-02-09 | Medivir Ab | Acyclic nucleoside derivatives |
US6703394B2 (en) | 1996-02-16 | 2004-03-09 | Medivir Ab | Acyclic nucleoside derivatives |
PT102030B (pt) * | 1996-07-20 | 1999-04-30 | Smithkline Beecham Plc | Processo para a apreparacao dos compostos penciclovir ou famciclovir que sao utesi como agentes antivirais |
GB9615276D0 (en) * | 1996-07-20 | 1996-09-04 | Smithkline Beecham Plc | Pharmaceuticals |
GB9615275D0 (en) * | 1996-07-20 | 1996-09-04 | Smithkline Beecham Plc | Pharmaceuticals |
GB9615253D0 (en) * | 1996-07-20 | 1996-09-04 | Smithkline Beecham Plc | Pharmaceuticals |
GB9807114D0 (en) * | 1998-04-02 | 1998-06-03 | Smithkline Beecham Plc | Novel process |
US6653318B1 (en) * | 1999-07-21 | 2003-11-25 | Yale University | 5-(E)-Bromovinyl uracil analogues and related pyrimidine nucleosides as anti-viral agents and methods of use |
US20050215787A1 (en) * | 2004-03-26 | 2005-09-29 | Joshi Ramesh A | An improved process for the preparation of purines |
GB2426247A (en) * | 2005-05-20 | 2006-11-22 | Arrow Int Ltd | Methods of preparing purine derivatives such as famciclovir |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3891757A (en) | 1971-11-11 | 1975-06-24 | Alza Corp | Anaesthetic topical and percutaneous administration with selected promoters |
GB1523865A (en) * | 1974-09-02 | 1978-09-06 | Wellcome Found | Purine compunds and salts thereof |
US4199574A (en) | 1974-09-02 | 1980-04-22 | Burroughs Wellcome Co. | Methods and compositions for treating viral infections and guanine acyclic nucleosides |
US4355032B2 (en) | 1981-05-21 | 1990-10-30 | 9-(1,3-dihydroxy-2-propoxymethyl)guanine as antiviral agent | |
NZ201662A (en) | 1981-08-26 | 1986-07-11 | Merck & Co Inc | 9-(1,3-(and 2,3)-dihydroxy-1-(and 2)-propoxy-methyl)guanine derivatives and methods for their preparation |
US4556659A (en) * | 1982-08-09 | 1985-12-03 | Syntex (U.S.A.) Inc. | Substituted 9-(1-0- or 3-0-monosubstituted or 1,3-Di-0-substituted propoxymethyl)-purines as antiviral agents |
US4609662A (en) * | 1982-10-14 | 1986-09-02 | Burroughs Wellcome Co. | Method for using purine derivatives |
NZ205955A (en) * | 1982-10-14 | 1988-02-29 | Wellcome Found | 2-amino-9-(2-hydroxyethoxymethyl)-9h-purine |
IL73682A (en) * | 1983-12-20 | 1991-08-16 | Medivir Ab | Antiviral pharmaceutical compositions containing 9-hydroxy aliphatic derivatives of guanine,some new such derivatives and process for their preparation |
EP0182024B1 (de) | 1984-09-20 | 1991-04-03 | Beecham Group Plc | Purin-Derivate und ihre pharmazeutische Verwendung |
-
1984
- 1984-12-21 SE SE8406538A patent/SE8406538D0/xx unknown
-
1985
- 1985-12-13 DE DE8585850398T patent/DE3575927D1/de not_active Expired - Lifetime
- 1985-12-13 AT AT85850398T patent/ATE50260T1/de not_active IP Right Cessation
- 1985-12-13 EP EP19850850398 patent/EP0186640B1/de not_active Expired - Lifetime
- 1985-12-19 JP JP60284503A patent/JPH0680061B2/ja not_active Expired - Lifetime
-
1988
- 1988-01-22 US US07/147,051 patent/US5036071A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
EP0186640B1 (de) | 1990-02-07 |
EP0186640A1 (de) | 1986-07-02 |
ATE50260T1 (de) | 1990-02-15 |
SE8406538D0 (sv) | 1984-12-21 |
US5036071A (en) | 1991-07-30 |
JPS61171481A (ja) | 1986-08-02 |
JPH0680061B2 (ja) | 1994-10-12 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |