ATE84032T1 - Benzimidazolderivate, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische praeparate. - Google Patents

Benzimidazolderivate, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische praeparate.

Info

Publication number
ATE84032T1
ATE84032T1 AT87850362T AT87850362T ATE84032T1 AT E84032 T1 ATE84032 T1 AT E84032T1 AT 87850362 T AT87850362 T AT 87850362T AT 87850362 T AT87850362 T AT 87850362T AT E84032 T1 ATE84032 T1 AT E84032T1
Authority
AT
Austria
Prior art keywords
manufacture
pharmaceutical preparations
preparations containing
benzimidazole derivatives
compounds
Prior art date
Application number
AT87850362T
Other languages
English (en)
Inventor
Tomas Boerje Alminger
Rolf Axel Bergman
Hans Bundgaard
Per Lennart Lindberg
Gunnel Elisabeth Sunden
Original Assignee
Haessle Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from SE8604998A external-priority patent/SE8604998D0/xx
Priority claimed from SE8605551A external-priority patent/SE8605551D0/xx
Priority claimed from SE8704049A external-priority patent/SE8704049D0/xx
Application filed by Haessle Ab filed Critical Haessle Ab
Application granted granted Critical
Publication of ATE84032T1 publication Critical patent/ATE84032T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6558—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
    • C07F9/65583—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system each of the hetero rings containing nitrogen as ring hetero atom
AT87850362T 1986-11-21 1987-11-20 Benzimidazolderivate, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische praeparate. ATE84032T1 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
SE8604998A SE8604998D0 (sv) 1986-11-21 1986-11-21 Novel pharmacological compounds
SE8605551A SE8605551D0 (sv) 1986-12-23 1986-12-23 Novel pharmacological compounds
SE8704049A SE8704049D0 (sv) 1987-10-16 1987-10-16 Novel pharmacological compounds
EP87850362A EP0279149B1 (de) 1986-11-21 1987-11-20 Benzimidazolderivate, Verfahren zu ihrer Herstellung und sie enthaltende pharmazeutische Präparate

Publications (1)

Publication Number Publication Date
ATE84032T1 true ATE84032T1 (de) 1993-01-15

Family

ID=27355365

Family Applications (1)

Application Number Title Priority Date Filing Date
AT87850362T ATE84032T1 (de) 1986-11-21 1987-11-20 Benzimidazolderivate, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische praeparate.

Country Status (24)

Country Link
EP (3) EP0279149B1 (de)
JP (1) JPH02500744A (de)
KR (1) KR890700125A (de)
AT (1) ATE84032T1 (de)
AU (1) AU612129B2 (de)
DE (1) DE3783356T2 (de)
DK (1) DK365488D0 (de)
EG (1) EG18379A (de)
ES (1) ES2052603T3 (de)
FI (1) FI892454A0 (de)
GR (1) GR3007385T3 (de)
HU (1) HU204814B (de)
IE (2) IE61178B1 (de)
IL (1) IL84504A (de)
IS (1) IS1565B (de)
LV (1) LV10954B (de)
MY (1) MY101784A (de)
NO (1) NO173998C (de)
NZ (2) NZ234564A (de)
PL (1) PL157655B1 (de)
PT (1) PT86186B (de)
RU (1) RU2062778C1 (de)
WO (1) WO1988003921A1 (de)
YU (1) YU47116B (de)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE8801907D0 (sv) * 1988-05-20 1988-05-20 Haessle Ab Novel pharmacological compounds
WO1990003373A1 (en) * 1988-09-20 1990-04-05 Hisamitsu Pharmaceutical Co., Inc. NOVEL DIBENZ[b,e]OXEPIN DERIVATIVES
SE8804629D0 (sv) * 1988-12-22 1988-12-22 Ab Haessle New therapeutically active compounds
IE64199B1 (en) * 1988-12-22 1995-07-12 Haessle Ab Compound with gastric acid inhibitory effect and process for its preparation
US4965269A (en) * 1989-12-20 1990-10-23 Ab Hassle Therapeutically active chloro substituted benzimidazoles
US5274099A (en) * 1989-12-20 1993-12-28 Aktiebolaget Hassle Therapeutically active fluoro substituted benzimidazoles
US5049674A (en) * 1989-12-20 1991-09-17 Aktiebolaget Hassle Therapeutically active fluoro substituted benzimidazoles
SE9002206D0 (sv) 1990-06-20 1990-06-20 Haessle Ab New compounds
AU649456B2 (en) * 1990-06-20 1994-05-26 Astra Aktiebolag Dialkoxy-pyridinyl-benzimidazole derivatives, process for their preparation and their pharmaceutical use
DE69132082T2 (de) * 1990-10-17 2000-08-31 Takeda Chemical Industries Ltd Pyridin-Derivate, Verfahren zu deren Herstellung und Anwendung
SE9103776D0 (sv) * 1991-12-19 1991-12-19 Astra Ab New compounds
DK0604657T3 (da) * 1992-05-21 2000-04-17 Otsuka Pharma Co Ltd Phosphonsyrediesterderivat
WO1994026279A1 (en) * 1993-05-18 1994-11-24 The Upjohn Company Bisphosphonate esters for treating gastric disorders
US6875872B1 (en) 1993-05-28 2005-04-05 Astrazeneca Compounds
AU6551198A (en) * 1997-05-30 1998-12-30 Dr. Reddy's Research Foundation Novel benzimidazole derivatives as antiulcer agents, process for their preparation and pharmaceutical compositions containing them
WO1999033846A2 (en) * 1997-12-31 1999-07-08 The University Of Kansas Water soluble prodrugs of secondary and tertiary amine containing drugs and methods of making thereof
EP1248790A1 (de) * 1999-12-17 2002-10-16 Ariad Pharmaceuticals, Inc. Protonenpumpe inhibitoren
US20040039027A1 (en) * 2000-10-12 2004-02-26 Keiji Kamiyama Benzimidazole compounds, process for producing the same and use thereof
US20040248941A1 (en) * 2001-09-25 2004-12-09 Keiji Kamiyama Benzimidazone compound, process for producing the same, and use thereof
JP5227795B2 (ja) * 2005-07-28 2013-07-03 インターベツト・インターナシヨナル・ベー・ベー 抗寄生虫活性を有する新規ベンゾイミダゾール（チオ）カルバメートおよびその合成
US10272070B2 (en) 2014-10-14 2019-04-30 The Board of Trustees of the Leland Stanford Junio r University Method for treating neurodegenerative diseases
HUE051771T2 (hu) 2015-12-15 2021-03-29 Univ Leland Stanford Junior Módszer a korral összefüggõ kognitív zavar és ideggyulladás megelõzésére és/vagy kezelésére
KR20210068399A (ko) 2018-08-06 2021-06-09 더 보드 오브 트러스티스 오브 더 리랜드 스탠포드 주니어 유니버시티 신경퇴행성 질병의 치료를 위한 피피에이알지씨1알파 활성제로서 2-아릴벤즈이미다졸
MX2022001820A (es) * 2019-08-20 2022-03-17 Ono Pharmaceutical Co Sal y forma cristalina de un compuesto que tiene actividad agonista para el receptor 5 de esfingosina-1-fosfato [acido (2s,3r,4e)-2-amino-3-hidroxioctadeca-4-enil-1-fosforico (s1p5).

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE418966B (sv) 1974-02-18 1981-07-06 Haessle Ab Analogiforfarande for framstellning av foreningar med magsyrasekretionsinhiberande verkan
SE416649B (sv) 1974-05-16 1981-01-26 Haessle Ab Forfarande for framstellning av foreningar som paverkar magsyrasekretionen
IN148930B (de) 1977-09-19 1981-07-25 Hoffmann La Roche
SE7804231L (sv) 1978-04-14 1979-10-15 Haessle Ab Magsyrasekretionsmedel
JPS5836312B2 (ja) * 1978-08-21 1983-08-08 日本電信電話株式会社 通信用平衡ケ−ブル線路の障害位置測定方式
JPS5687818A (en) * 1979-12-19 1981-07-16 Ishikawajima Harima Heavy Ind Co Ltd Reflex type position detector
US4359465A (en) * 1980-07-28 1982-11-16 The Upjohn Company Methods for treating gastrointestinal inflammation
CH644116A5 (de) 1980-08-21 1984-07-13 Hoffmann La Roche Imidazolderivate.
JPS57137860A (en) * 1981-02-20 1982-08-25 Sumitomo Electric Ind Ltd Optical tachometer
JPS5999597A (ja) * 1982-11-30 1984-06-08 株式会社東芝 光学測定装置
SE8300736D0 (sv) * 1983-02-11 1983-02-11 Haessle Ab Novel pharmacologically active compounds
JPS6020051U (ja) * 1983-07-19 1985-02-12 三洋電機株式会社 カセツト収納装置
AU568441B2 (en) * 1984-09-24 1987-12-24 Upjohn Company, The 2-(pyridylalkenesulfinyl) benzimidazole derivatives
IL76839A (en) * 1984-10-31 1988-08-31 Byk Gulden Lomberg Chem Fab Picoline derivatives,processes for the preparation thereof and pharmaceutical compositions containing the same
SE8505112D0 (sv) * 1985-10-29 1985-10-29 Haessle Ab Novel pharmacological compounds

Also Published As

Publication number Publication date
GR3007385T3 (de) 1993-07-30
NZ222495A (en) 1991-04-26
IE940326L (en) 1988-05-21
FI892454A (fi) 1989-05-19
AU8330287A (en) 1988-06-16
YU47116B (sh) 1994-12-28
NO883229L (no) 1988-09-16
AU612129B2 (en) 1991-07-04
PT86186A (en) 1987-12-01
EP0510719A1 (de) 1992-10-28
JPH02500744A (ja) 1990-03-15
DE3783356T2 (de) 1993-04-15
IE873125L (en) 1988-05-21
IS3284A7 (is) 1988-05-22
EP0279149A3 (en) 1988-08-31
EP0279149A2 (de) 1988-08-24
ES2052603T3 (es) 1994-07-16
RU2062778C1 (ru) 1996-06-27
PL268927A1 (en) 1989-01-23
NO173998C (no) 1994-03-02
NO883229D0 (no) 1988-07-20
EG18379A (en) 1992-11-30
PT86186B (pt) 1990-08-31
EP0279149B1 (de) 1992-12-30
IL84504A (en) 1994-10-07
WO1988003921A1 (en) 1988-06-02
EP0332647A1 (de) 1989-09-20
YU211087A (en) 1988-12-31
HU204814B (en) 1992-02-28
FI892454A0 (fi) 1989-05-19
LV10954B (en) 1996-08-20
IS1565B (is) 1994-12-13
DK365488A (da) 1988-07-01
DK365488D0 (da) 1988-07-01
IE61178B1 (en) 1994-10-05
DE3783356D1 (de) 1993-02-11
KR890700125A (ko) 1989-03-02
PL157655B1 (pl) 1992-06-30
HUT51269A (en) 1990-04-28
LV10954A (lv) 1995-12-20
NO173998B (no) 1993-11-22
NZ234564A (en) 1991-04-26
MY101784A (en) 1992-01-17

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee