DK174986B1 - Anvendelse af purinderivater til fremstilling af et lægemiddel - Google Patents
Anvendelse af purinderivater til fremstilling af et lægemiddel Download PDFInfo
- Publication number
- DK174986B1 DK174986B1 DK199002649A DK264990A DK174986B1 DK 174986 B1 DK174986 B1 DK 174986B1 DK 199002649 A DK199002649 A DK 199002649A DK 264990 A DK264990 A DK 264990A DK 174986 B1 DK174986 B1 DK 174986B1
- Authority
- DK
- Denmark
- Prior art keywords
- hydroxy
- amino
- compounds
- acid
- alkyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
- C07F9/65616—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings containing the ring system having three or more than three double bonds between ring members or between ring members and non-ring members, e.g. purine or analogs
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6564—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms
- C07F9/6571—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and oxygen atoms as the only ring hetero atoms
- C07F9/657163—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and oxygen atoms as the only ring hetero atoms the ring phosphorus atom being bound to at least one carbon atom
- C07F9/657181—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and oxygen atoms as the only ring hetero atoms the ring phosphorus atom being bound to at least one carbon atom the ring phosphorus atom and, at least, one ring oxygen atom being part of a (thio)phosphonic acid derivative
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Virology (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Communicable Diseases (AREA)
- Biochemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Oncology (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Saccharide Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE8801729A SE8801729D0 (sv) | 1988-05-06 | 1988-05-06 | Purine derivatives for use in therapy |
| SE8801729 | 1988-05-06 | ||
| PCT/SE1989/000255 WO1989010923A1 (en) | 1988-05-06 | 1989-05-05 | Derivatives of purine, process for their preparation and a pharmaceutical preparation |
| SE8900255 | 1989-05-05 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| DK264990A DK264990A (da) | 1990-11-05 |
| DK264990D0 DK264990D0 (da) | 1990-11-05 |
| DK174986B1 true DK174986B1 (da) | 2004-04-13 |
Family
ID=20372263
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK199002649A DK174986B1 (da) | 1988-05-06 | 1990-11-05 | Anvendelse af purinderivater til fremstilling af et lægemiddel |
Country Status (18)
| Country | Link |
|---|---|
| EP (1) | EP0343133B1 (sv) |
| JP (1) | JP2866688B2 (sv) |
| KR (1) | KR0141913B1 (sv) |
| AT (1) | ATE74603T1 (sv) |
| CA (1) | CA1340909C (sv) |
| DE (1) | DE68901153D1 (sv) |
| DK (1) | DK174986B1 (sv) |
| ES (1) | ES2033548T3 (sv) |
| FI (1) | FI98729C (sv) |
| GR (1) | GR3004482T3 (sv) |
| HU (1) | HU207082B (sv) |
| IE (1) | IE62066B1 (sv) |
| IL (1) | IL90166A (sv) |
| MY (1) | MY108541A (sv) |
| NZ (1) | NZ229002A (sv) |
| PT (1) | PT90478B (sv) |
| SE (1) | SE8801729D0 (sv) |
| WO (1) | WO1989010923A1 (sv) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8904855D0 (en) * | 1989-03-03 | 1989-04-12 | Beecham Group Plc | Pharmaceutical treatment |
| US6069252A (en) * | 1990-02-01 | 2000-05-30 | Emory University | Method of resolution and antiviral activity of 1,3-oxathiolane nucleoside enantiomers |
| US5356886A (en) * | 1990-07-19 | 1994-10-18 | Beecham Group P.L.C. | Antiviral phosphono-alken derivatives of purines |
| GB9020932D0 (en) * | 1990-09-26 | 1990-11-07 | Wellcome Found | Heterocyclic compounds |
| US5208221A (en) * | 1990-11-29 | 1993-05-04 | Bristol-Myers Squibb Company | Antiviral (phosphonomethoxy) methoxy purine/pyrimidine derivatives |
| US5334525A (en) * | 1992-08-28 | 1994-08-02 | Fox Chase Cancer Center | Hepadnavirus polymerase gene product having RNA-dependent DNA priming and reverse transcriptase activities and methods of measuring the activities thereof |
| US5360714A (en) * | 1992-08-28 | 1994-11-01 | Fox Chase Cancer Center | Hepadnavirus polymerase gene product having RNA-dependent DNA priming and reverse transcriptase activities and methods of measuring the activities thereof |
| US5656745A (en) * | 1993-09-17 | 1997-08-12 | Gilead Sciences, Inc. | Nucleotide analogs |
| US5798340A (en) | 1993-09-17 | 1998-08-25 | Gilead Sciences, Inc. | Nucleotide analogs |
| AU690587B2 (en) * | 1993-09-17 | 1998-04-30 | Gilead Sciences, Inc. | Method for dosing therapeutic compounds |
| DE19540798A1 (de) * | 1995-11-02 | 1997-05-07 | Hoechst Ag | Alkylxanthinphosphonate und Alkylxanthinphosphinoxide und deren Verwendung als Arzneimittel |
| US20030040467A1 (en) | 1998-06-15 | 2003-02-27 | Mary Ann Pelleymounter | Ig/ob fusions and uses thereof. |
| US5717095A (en) * | 1995-12-29 | 1998-02-10 | Gilead Sciences, Inc. | Nucleotide analogs |
| CA2239020A1 (en) * | 1995-12-29 | 1997-07-10 | Norbert W. Bischofberger | Nucleotide analogs |
| US5869493A (en) | 1996-02-16 | 1999-02-09 | Medivir Ab | Acyclic nucleoside derivatives |
| US6703394B2 (en) | 1996-02-16 | 2004-03-09 | Medivir Ab | Acyclic nucleoside derivatives |
| US6184376B1 (en) | 1997-02-10 | 2001-02-06 | Mediver Ab | Synthesis of acyclic nucleoside derivatives |
| EP0971923B1 (en) * | 1997-02-10 | 2002-11-06 | Medivir Ab | Synthesis of acyclic nucleoside derivatives |
| JP2009298785A (ja) * | 1997-02-10 | 2009-12-24 | Medivir Ab | 非環状ヌクレオシド誘導体の合成 |
| US6753322B2 (en) | 2000-06-06 | 2004-06-22 | Pfizer Inc | 2-aminocarbonyl-9H-purine derivatives |
| EP1440072A4 (en) | 2001-10-30 | 2005-02-02 | Conforma Therapeutic Corp | PURINE ANALOGS HAVING HSP90 INHIBITORY ACTIVITY |
| US7138402B2 (en) | 2003-09-18 | 2006-11-21 | Conforma Therapeutics Corporation | Pyrrolopyrimidines and related analogs as HSP90-inhibitors |
| TWI332507B (en) | 2002-11-19 | 2010-11-01 | Hoffmann La Roche | Antiviral nucleoside derivatives |
| JP2008534609A (ja) | 2005-03-30 | 2008-08-28 | コンフォーマ・セラピューティクス・コーポレイション | Ｈｓｐ９０阻害剤としてのアルキニルピロロピリミジンおよび関連類似体 |
| CA2733390A1 (en) | 2008-08-01 | 2010-02-04 | Bioxiness Pharmaceuticals, Inc. | Methionine analogs and methods of using same |
| CN102250126A (zh) * | 2010-05-18 | 2011-11-23 | 北京化工大学 | 一种双嘌呤类衍生物及其合成 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE33653T1 (de) * | 1982-10-14 | 1988-05-15 | Wellcome Found | Antivirale purinderivate. |
| CS233665B1 (en) * | 1983-01-06 | 1985-03-14 | Antonin Holy | Processing of isomere o-phosphonylmethylderivative of anantiomere racemic vicinal diene |
| IL73682A (en) * | 1983-12-20 | 1991-08-16 | Medivir Ab | Antiviral pharmaceutical compositions containing 9-hydroxy aliphatic derivatives of guanine,some new such derivatives and process for their preparation |
| SE8406538D0 (sv) * | 1984-12-21 | 1984-12-21 | Astra Laekemedel Ab | Novel derivatives of purine |
| MY101126A (en) * | 1985-12-13 | 1991-07-31 | Beecham Group Plc | Novel compounds |
-
1988
- 1988-05-06 SE SE8801729A patent/SE8801729D0/sv unknown
-
1989
- 1989-05-03 IL IL9016689A patent/IL90166A/en active IP Right Grant
- 1989-05-04 NZ NZ229002A patent/NZ229002A/en unknown
- 1989-05-05 HU HU893004A patent/HU207082B/hu not_active IP Right Cessation
- 1989-05-05 AT AT89850146T patent/ATE74603T1/de not_active IP Right Cessation
- 1989-05-05 WO PCT/SE1989/000255 patent/WO1989010923A1/en active IP Right Grant
- 1989-05-05 JP JP1505738A patent/JP2866688B2/ja not_active Expired - Fee Related
- 1989-05-05 EP EP89850146A patent/EP0343133B1/en not_active Expired - Lifetime
- 1989-05-05 MY MYPI89000618A patent/MY108541A/en unknown
- 1989-05-05 CA CA000598887A patent/CA1340909C/en not_active Expired - Fee Related
- 1989-05-05 ES ES198989850146T patent/ES2033548T3/es not_active Expired - Lifetime
- 1989-05-05 DE DE8989850146T patent/DE68901153D1/de not_active Expired - Fee Related
- 1989-05-05 IE IE147289A patent/IE62066B1/en not_active IP Right Cessation
- 1989-05-15 PT PT90478A patent/PT90478B/pt not_active IP Right Cessation
-
1990
- 1990-01-06 KR KR90700035A patent/KR0141913B1/ko not_active IP Right Cessation
- 1990-11-05 DK DK199002649A patent/DK174986B1/da not_active IP Right Cessation
- 1990-11-05 FI FI905475A patent/FI98729C/sv active IP Right Grant
-
1992
- 1992-05-05 GR GR920400840T patent/GR3004482T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP0343133A1 (en) | 1989-11-23 |
| JP2866688B2 (ja) | 1999-03-08 |
| PT90478A (pt) | 1989-11-30 |
| AU3572689A (en) | 1989-11-29 |
| CA1340909C (en) | 2000-02-22 |
| IL90166A (en) | 1996-09-12 |
| FI98729B (sv) | 1997-04-30 |
| DK264990A (da) | 1990-11-05 |
| AU626300B2 (en) | 1992-07-30 |
| DE68901153D1 (de) | 1992-05-14 |
| NZ229002A (en) | 1997-05-26 |
| HUT57767A (en) | 1991-12-30 |
| PT90478B (pt) | 1994-08-31 |
| JPH03504243A (ja) | 1991-09-19 |
| ATE74603T1 (de) | 1992-04-15 |
| KR0141913B1 (en) | 1998-06-01 |
| ES2033548T3 (es) | 1993-03-16 |
| EP0343133B1 (en) | 1992-04-08 |
| DK264990D0 (da) | 1990-11-05 |
| IE891472L (en) | 1989-11-06 |
| FI98729C (sv) | 1997-08-11 |
| WO1989010923A1 (en) | 1989-11-16 |
| HU207082B (en) | 1993-03-01 |
| IL90166A0 (en) | 1989-12-15 |
| HU893004D0 (en) | 1991-09-30 |
| IE62066B1 (en) | 1994-12-14 |
| FI905475A0 (sv) | 1990-11-05 |
| SE8801729D0 (sv) | 1988-05-06 |
| MY108541A (en) | 1996-10-31 |
| GR3004482T3 (sv) | 1993-03-31 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PBP | Patent lapsed |
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