MY101126A - Novel compounds - Google Patents
Novel compoundsInfo
- Publication number
- MY101126A MY101126A MYPI86000187A MYPI19860187A MY101126A MY 101126 A MY101126 A MY 101126A MY PI86000187 A MYPI86000187 A MY PI86000187A MY PI19860187 A MYPI19860187 A MY PI19860187A MY 101126 A MY101126 A MY 101126A
- Authority
- MY
- Malaysia
- Prior art keywords
- hydrogen
- ch2oh
- alkyl
- phenyl
- hydroxy
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/50—Three nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
- C07D473/16—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
- C07D473/18—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 one oxygen and one nitrogen atom, e.g. guanine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
- C07D473/32—Nitrogen atom
Abstract
COMPOUNDS OF FORMULA (1) AND A PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF: (FORMULA 1) WHEREIN: R1 IS HYDROGEN OR CH2OH; R2 IS HYDROGEN OR, (WHEN R1 AND R2 IS HYDROGEN), HYDROXY OR CH2OH; R? IS CH2OH OR, (WHEN R1 AND R2 ARE BOTH HYDROGEN), CH (OH) CH2 OH; R4 IS HYDROGEN, HYDROXY, AMINO OR OR5 WHEREIN R5 IS C1-6 ALKYL, PHENYL OR PHENYL C1-2 ALKYL EITHER OF WHICH PHENYL MOIETIES MAY BE SUBSTITUTED BY ONE OR TWO HALO, C1-4 ALKYL OR C1-4 ALKOXY GROUPS; AND IN WHICH ANY OH GROUPS IN R1, R2 AND/OR R3 MAY BE IN THE FORM OF O-ACYL, PHOSPHATE, CYCLIC ACETAL OR CYCLIC CARBONATE DERIVATIVES THEREOF; HAVING ANTIVIRAL ACTIVITY, PROCESSES AND INTERMEDIATES FOR THEIR PREPARATION AND THEIR USE AS PHARMACEUTICALS.
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB858530813A GB8530813D0 (en) | 1985-12-13 | 1985-12-13 | Compounds |
| GB868603228A GB8603228D0 (en) | 1986-02-10 | 1986-02-10 | Compounds |
| GB868620849A GB8620849D0 (en) | 1986-08-28 | 1986-08-28 | Compounds |
| GB868626041A GB8626041D0 (en) | 1986-10-31 | 1986-10-31 | Compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MY101126A true MY101126A (en) | 1991-07-31 |
Family
ID=27449713
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MYPI86000187A MY101126A (en) | 1985-12-13 | 1986-12-10 | Novel compounds |
Country Status (19)
| Country | Link |
|---|---|
| EP (1) | EP0242482B1 (en) |
| JP (1) | JPH085886B2 (en) |
| KR (1) | KR940010033B1 (en) |
| AT (1) | ATE127466T1 (en) |
| AU (1) | AU599066B2 (en) |
| CA (1) | CA1296726C (en) |
| DE (1) | DE3650384T2 (en) |
| DK (1) | DK166823B1 (en) |
| ES (1) | ES2076139T3 (en) |
| FI (1) | FI85143C (en) |
| GR (1) | GR3018105T3 (en) |
| HU (1) | HU200461B (en) |
| IL (1) | IL80947A (en) |
| MA (1) | MA20828A1 (en) |
| MY (1) | MY101126A (en) |
| NO (1) | NO166226C (en) |
| NZ (1) | NZ218598A (en) |
| PL (3) | PL150925B1 (en) |
| PT (1) | PT83911B (en) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8602346D0 (en) * | 1986-01-30 | 1986-03-05 | Wellcome Found | Antiviral combinations |
| GB8713695D0 (en) * | 1987-06-11 | 1987-07-15 | Beecham Group Plc | Process |
| GB8712744D0 (en) * | 1987-05-30 | 1987-07-01 | Beecham Group Plc | Active compounds |
| US4965270A (en) * | 1987-05-30 | 1990-10-23 | Beecham Group P.L.C. | Purine derivatives |
| GB8724765D0 (en) * | 1987-10-22 | 1987-11-25 | Beecham Group Plc | Process |
| SE8801729D0 (en) * | 1988-05-06 | 1988-05-06 | Astra Ab | PURINE DERIVATIVES FOR USE IN THERAPY |
| EP0353955A3 (en) * | 1988-08-02 | 1991-08-14 | Beecham Group Plc | Novel compounds |
| DK135489D0 (en) * | 1989-03-20 | 1989-03-20 | Gea Farmaceutisk Fabrik As | PROCEDURE FOR THE PREPARATION OF 9-SUBSTITUTED GUANINE DERIVATIVES AND INTERMEDIATES FOR USING THE PROCEDURE |
| GB8907173D0 (en) * | 1989-03-30 | 1989-05-10 | Beecham Group Plc | Novel compounds |
| GB8912043D0 (en) * | 1989-05-25 | 1989-07-12 | Beecham Group Plc | Novel compounds |
| GB8918827D0 (en) * | 1989-08-17 | 1989-09-27 | Beecham Group Plc | Novel compounds |
| US5252575A (en) * | 1989-08-17 | 1993-10-12 | Beecham Group P.L.C. | Antiviral purine derivatives with improved gastrointestinal absorption |
| GB9107896D0 (en) * | 1991-04-13 | 1991-05-29 | Smithkline Beecham Plc | Pharmaceuticals |
| JP2720681B2 (en) * | 1992-01-06 | 1998-03-04 | 株式会社村田製作所 | Mobile object movement detection device |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4347360A (en) * | 1980-09-16 | 1982-08-31 | Ens Bio Logicals Inc. | Ring open nucleoside analogues |
| AU573540B2 (en) * | 1982-10-14 | 1988-06-16 | Wellcome Foundation Limited, The | 6-hydrogen purine derivatives |
| PT78769A (en) * | 1983-06-24 | 1984-07-01 | Merck & Co Inc | Process for preparing (s)-9-(2,3-dihydroxy-1-propoxymethyl)guanine and derivatives thereof useful as antiviral agents |
| KR910000198B1 (en) * | 1984-12-12 | 1991-01-23 | 신텍스(유.에스.에이.) 인코포레이티드 | Process for preparing alkoxymethyl ethers and alkoxymethyl esters of glycerols |
-
1986
- 1986-12-10 MY MYPI86000187A patent/MY101126A/en unknown
- 1986-12-11 EP EP86309667A patent/EP0242482B1/en not_active Expired - Lifetime
- 1986-12-11 DE DE3650384T patent/DE3650384T2/en not_active Expired - Lifetime
- 1986-12-11 AU AU66443/86A patent/AU599066B2/en not_active Ceased
- 1986-12-11 PT PT83911A patent/PT83911B/en not_active IP Right Cessation
- 1986-12-11 ES ES86309667T patent/ES2076139T3/en not_active Expired - Lifetime
- 1986-12-11 NO NO865014A patent/NO166226C/en unknown
- 1986-12-11 NZ NZ218598A patent/NZ218598A/en unknown
- 1986-12-11 CA CA000525073A patent/CA1296726C/en not_active Expired - Fee Related
- 1986-12-11 IL IL80947A patent/IL80947A/en not_active IP Right Cessation
- 1986-12-11 DK DK595886A patent/DK166823B1/en not_active IP Right Cessation
- 1986-12-11 KR KR1019860010590A patent/KR940010033B1/en not_active IP Right Cessation
- 1986-12-11 PL PL1986272031A patent/PL150925B1/en unknown
- 1986-12-11 AT AT86309667T patent/ATE127466T1/en not_active IP Right Cessation
- 1986-12-11 PL PL1986262930A patent/PL150841B1/en unknown
- 1986-12-11 PL PL1986272032A patent/PL150926B1/en unknown
- 1986-12-12 MA MA21060A patent/MA20828A1/en unknown
- 1986-12-12 JP JP61295096A patent/JPH085886B2/en not_active Expired - Lifetime
- 1986-12-12 HU HU865196A patent/HU200461B/en not_active IP Right Cessation
- 1986-12-12 FI FI865075A patent/FI85143C/en not_active IP Right Cessation
-
1995
- 1995-11-16 GR GR950403221T patent/GR3018105T3/en unknown
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