TNSN89026A1 - Methode de detection de sequences de nucleotides - Google Patents

Methode de detection de sequences de nucleotides

Info

Publication number
TNSN89026A1
TNSN89026A1 TNTNSN89026A TNSN89026A TNSN89026A1 TN SN89026 A1 TNSN89026 A1 TN SN89026A1 TN TNSN89026 A TNTNSN89026 A TN TNSN89026A TN SN89026 A TNSN89026 A TN SN89026A TN SN89026 A1 TNSN89026 A1 TN SN89026A1
Authority
TN
Tunisia
Prior art keywords
nucleotide sequences
detecting nucleotide
detecting
kits
production
Prior art date
Application number
TNTNSN89026A
Other languages
English (en)
Inventor
Clive Robert Newton
Alexander Fred Markham
Original Assignee
Ici Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26293607&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=TNSN89026(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GB888805692A external-priority patent/GB8805692D0/en
Priority claimed from GB888814170A external-priority patent/GB8814170D0/en
Application filed by Ici Plc filed Critical Ici Plc
Publication of TNSN89026A1 publication Critical patent/TNSN89026A1/fr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844Nucleic acid amplification reactions
    • C12Q1/686Polymerase chain reaction [PCR]
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844Nucleic acid amplification reactions
    • C12Q1/6858Allele-specific amplification
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Nonwoven Fabrics (AREA)
  • Communication Cables (AREA)
  • Suspension Of Electric Lines Or Cables (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

PRODUCTION DE KITS DESTINES A EFFECTUER LES TESTS DE DIAGNOSTIC DE PERTURBATIONS GENETIQUES
TNTNSN89026A 1988-03-10 1989-03-09 Methode de detection de sequences de nucleotides TNSN89026A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB888805692A GB8805692D0 (en) 1988-03-10 1988-03-10 Method of detecting nucleotide sequences
GB888814170A GB8814170D0 (en) 1988-06-15 1988-06-15 Method of detecting nucleotide sequences

Publications (1)

Publication Number Publication Date
TNSN89026A1 true TNSN89026A1 (fr) 1991-02-04

Family

ID=26293607

Family Applications (1)

Application Number Title Priority Date Filing Date
TNTNSN89026A TNSN89026A1 (fr) 1988-03-10 1989-03-09 Methode de detection de sequences de nucleotides

Country Status (26)

Country Link
US (1) US5595890A (fr)
EP (1) EP0332435B2 (fr)
JP (1) JP2853864B2 (fr)
KR (1) KR970003151B1 (fr)
CN (1) CN1034673C (fr)
AT (1) ATE75262T1 (fr)
AU (1) AU614584B2 (fr)
BG (1) BG87585A (fr)
BR (1) BR8901136A (fr)
CA (1) CA1323592C (fr)
DE (1) DE68901285D1 (fr)
DK (1) DK175527B1 (fr)
ES (1) ES2039294T5 (fr)
FI (1) FI891126A (fr)
GR (2) GR3004442T3 (fr)
HU (1) HUT52565A (fr)
IE (1) IE61148B1 (fr)
IL (1) IL89545A (fr)
MY (1) MY104957A (fr)
NO (1) NO174825B (fr)
NZ (1) NZ228266A (fr)
PL (1) PL162338B1 (fr)
PT (1) PT89980B (fr)
TN (1) TNSN89026A1 (fr)
YU (1) YU49789A (fr)
ZW (1) ZW3388A1 (fr)

Families Citing this family (257)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4038804A1 (de) * 1990-10-09 1992-04-16 Boehringer Mannheim Gmbh Verfahren zur genus- oder/und spezies-spezifischen detektion von bakterien in einer probenfluessigkeit
EP0333465B1 (fr) * 1988-03-18 1994-07-13 Baylor College Of Medicine Détection de mutations utilisant des oligonucléotides d'amorce compétitives
FR2650840B1 (fr) * 1989-08-11 1991-11-29 Bertin & Cie Procede rapide de detection et/ou d'identification d'une seule base sur une sequence d'acide nucleique, et ses applications
GB8920097D0 (en) * 1989-09-06 1989-10-18 Ici Plc Amplification processes
JPH03123500A (ja) * 1989-10-06 1991-05-27 Canon Inc 核酸の分別方法
GB9001181D0 (en) * 1990-01-18 1990-03-21 Imp Cancer Res Tech Genetic assay
IL97222A (en) * 1990-02-16 1995-08-31 Orion Yhtymae Oy Method and Responder for Determining Special Changes to Nucleotide
US6013431A (en) 1990-02-16 2000-01-11 Molecular Tool, Inc. Method for determining specific nucleotide variations by primer extension in the presence of mixture of labeled nucleotides and terminators
GB9006924D0 (en) * 1990-03-28 1990-05-23 Imperial College Prognosis of hepatitis infection
EP0463395B1 (fr) * 1990-06-22 1997-05-14 F. Hoffmann-La Roche Ag Dépistage des métabolisateurs faibles de drogues
US5844108A (en) * 1990-06-22 1998-12-01 Roche Molecular Systems, Inc. Primers targeted to NAT2 gene for detection of poor metabolizers of drugs
GB9019512D0 (en) * 1990-09-06 1990-10-24 Ici Plc Assay method
FR2668162B1 (fr) * 1990-10-17 1993-01-22 Eurobio Lab Fragments d'adn, procede et coffret de diagnostic pour la detection des porteurs de la mutation delta-f-508 responsable de la mucoviscidose.
IE66125B1 (en) * 1991-01-31 1995-12-13 Zeneca Ltd Detection method for variant nucleotides
US6004744A (en) 1991-03-05 1999-12-21 Molecular Tool, Inc. Method for determining nucleotide identity through extension of immobilized primer
US5853989A (en) * 1991-08-27 1998-12-29 Zeneca Limited Method of characterisation of genomic DNA
GB2259138B (en) * 1991-08-27 1995-08-23 Ici Plc Minisatellite variant repeat (MVR-PRC) mapping
DE4129653A1 (de) * 1991-09-06 1993-03-11 Boehringer Mannheim Gmbh Verfahren zum nachweis aehnlicher nukleinsaeuren
IL103935A0 (en) * 1991-12-04 1993-05-13 Du Pont Method for the identification of microorganisms by the utilization of directed and arbitrary dna amplification
US5541060A (en) * 1992-04-22 1996-07-30 Arch Development Corporation Detection of glucokinase-linked early-onset non-insulin-dependent diabetes mellitus
US6207368B1 (en) 1992-08-04 2001-03-27 Beckman Coulter, Inc. Methods and reagents for controlling chain extension and ligation chain reactions
US6180338B1 (en) 1992-08-04 2001-01-30 Beckman Coulter, Inc. Method, reagent and kit for the detection and amplification of nucleic acid sequences
WO1994008047A1 (fr) * 1992-09-25 1994-04-14 Abbott Laboratories Procede d'amplification en chaine par ligase pour la detection de petites mutations
US6335184B1 (en) 1993-07-23 2002-01-01 Bio-Rad Laboratories, Inc. Linked linear amplification of nucleic acids
EP0710296A4 (fr) * 1993-07-23 1999-05-26 Bio Rad Laboratories Amplification lineaire enchainee d'acides nucleiques
WO1995021270A2 (fr) * 1994-02-04 1995-08-10 Beckman Instruments, Inc. Procede, reactif et kit pour la detection et l'amplification de sequences d'acides nucleiques
EP0705902B2 (fr) 1994-08-12 2008-08-06 The University of Utah Research Foundation Sondes d'acide nucléique comprenant un fragment gène de susceptibilité du cancer du sein et des ovaires associé à 17Q
CA2196797C (fr) 1994-08-12 2000-10-10 Donna M. Shattuck-Eidens Polymorphismes et mutations in vivo chez le gene de susceptibilite 17q associe au cancer du sein et des ovaires
FR2737732B1 (fr) * 1995-08-07 1997-10-10 Ass Francaise Contre La Myopat Test co-dominant de diagnostic genetique
US5837492A (en) 1995-12-18 1998-11-17 Myriad Genetics, Inc. Chromosome 13-linked breast cancer susceptibility gene
WO1997022689A1 (fr) 1995-12-18 1997-06-26 Myriad Genetics, Inc. Gene de predisposition au cancer du sein lie au chromosome 13
ES2325820T3 (es) 1995-12-22 2009-09-18 University Of Utah Research Foundation Gen del sindrome qt largo que codifica kvlqt1 y su asociacion con mink.
NO960163D0 (no) * 1996-01-15 1996-01-15 Thomas Berg Mutasjonsdeteksjon av bovin
US5612473A (en) * 1996-01-16 1997-03-18 Gull Laboratories Methods, kits and solutions for preparing sample material for nucleic acid amplification
WO1997035033A1 (fr) 1996-03-19 1997-09-25 Molecular Tool, Inc. Methode de determination de la sequence nucleotidique d'un polynucleotide
GB9609441D0 (en) * 1996-05-04 1996-07-10 Zeneca Ltd Process
US6361940B1 (en) 1996-09-24 2002-03-26 Qiagen Genomics, Inc. Compositions and methods for enhancing hybridization and priming specificity
IL119342A0 (en) * 1996-10-02 1997-01-10 Yeda Research And Development C Methods for priming and DNA sequencing
US5888778A (en) * 1997-06-16 1999-03-30 Exact Laboratories, Inc. High-throughput screening method for identification of genetic mutations or disease-causing microorganisms using segmented primers
US6566101B1 (en) 1997-06-16 2003-05-20 Anthony P. Shuber Primer extension methods for detecting nucleic acids
GB9721240D0 (en) * 1997-10-08 1997-12-03 Zeneca Ltd Assay
US6794133B1 (en) 1997-12-11 2004-09-21 The General Hospital Corporation Broad range PCR amplification techniques
WO1999044045A1 (fr) * 1998-02-27 1999-09-02 Massachusetts Institute Of Technology Detection de molecule simple par diffusion raman exalte de surface et utilisations pour le sequençage d'adn et d'arn
GB9812768D0 (en) 1998-06-13 1998-08-12 Zeneca Ltd Methods
US6207379B1 (en) 1998-09-11 2001-03-27 One Lambda Method for amplification of DNA
NZ512088A (en) 1998-12-08 2004-01-30 Children S Hospital And Region Polymorphic loci that differentiate escherichia coli 0157:H7 from other strains
US6280947B1 (en) 1999-08-11 2001-08-28 Exact Sciences Corporation Methods for detecting nucleotide insertion or deletion using primer extension
US6503718B2 (en) 1999-01-10 2003-01-07 Exact Sciences Corporation Methods for detecting mutations using primer extension for detecting disease
EP1161554B1 (fr) 1999-03-18 2011-03-09 Exiqon A/S Detection de mutations dans des genes par des amorces de lna specifiques
US20030207295A1 (en) * 1999-04-20 2003-11-06 Kevin Gunderson Detection of nucleic acid reactions on bead arrays
US20060275782A1 (en) * 1999-04-20 2006-12-07 Illumina, Inc. Detection of nucleic acid reactions on bead arrays
EP1061134A3 (fr) * 1999-06-17 2003-01-08 Becton Dickinson and Company Oligonucléotides pour l'amplification et la détection des gènes de l'hémochromatose
US20020025519A1 (en) * 1999-06-17 2002-02-28 David J. Wright Methods and oligonucleotides for detecting nucleic acid sequence variations
US20030165913A1 (en) * 1999-06-17 2003-09-04 Sha-Sha Wang Methods for detecting nucleic acid sequence variations
AU5882000A (en) 1999-06-22 2001-01-09 Invitrogen Corporation Improved primers and methods for the detection and discrimination of nucleic acids
US6830902B1 (en) 1999-07-02 2004-12-14 Invitrogen Corporation Compositions and methods for enhanced sensitivity and specificity of nucleic acid synthesis
EP1072679A3 (fr) * 1999-07-20 2002-07-31 Agilent Technologies, Inc. (a Delaware corporation) Procédé de préparation de molécules d'acide nucléique ayant une structure secondaire diminuée
DE10038229B4 (de) 1999-08-24 2011-06-09 LG Electronics Inc., Kangnam-gu Verfahren und Vorrichtung zur Ratenanpassung in einem Mobilkommunikationssystem
US6528066B1 (en) * 1999-09-14 2003-03-04 University Of Iowa Research Foundation Variant varicella-zoster viruses and methods of use
AU2000278349A1 (en) * 1999-09-28 2001-04-30 Genaissance Pharmaceuticals, Inc. Drug target isogenes: polymorphisms in the interleukin 13 gene
US20030148301A1 (en) * 1999-12-10 2003-08-07 Toshiya Aono Method of detecting nucleotide polymorphism
WO2003074738A1 (fr) * 2000-01-18 2003-09-12 Quantom Dot Corporation Nanocristaux semi-conducteurs marques avec des oligonucleotides, utilises dans le cadre de dosages microbiologiques et de l'hybridation in situ par fluorescence
US7582420B2 (en) 2001-07-12 2009-09-01 Illumina, Inc. Multiplex nucleic acid reactions
US7955794B2 (en) * 2000-09-21 2011-06-07 Illumina, Inc. Multiplex nucleic acid reactions
US8076063B2 (en) * 2000-02-07 2011-12-13 Illumina, Inc. Multiplexed methylation detection methods
US20050214825A1 (en) * 2000-02-07 2005-09-29 John Stuelpnagel Multiplex sample analysis on universal arrays
US7659054B1 (en) * 2000-05-23 2010-02-09 Nuvelo, Inc. Methods for genetic analysis of DNA to detect sequence variances
US7435541B2 (en) * 2000-05-23 2008-10-14 Sequenom, Inc. Restriction enzyme genotyping
WO2002004673A1 (fr) * 2000-07-12 2002-01-17 Bionex, Inc. Procede pour detecter une variation de sequence dans un acide nucleique
JP3638516B2 (ja) * 2000-09-28 2005-04-13 株式会社日立製作所 核酸検出方法および核酸検出キット
US6428964B1 (en) 2001-03-15 2002-08-06 Exact Sciences Corporation Method for alteration detection
EP1373574A4 (fr) * 2001-03-30 2007-01-03 Ge Healthcare Bio Sciences Ab Analyse par biopuces de polymorphismes simple nucl otide
CN1186456C (zh) * 2001-04-30 2005-01-26 曹卫 通用模板核酸检测方法和试剂盒
US7407943B2 (en) 2001-08-01 2008-08-05 Isis Pharmaceuticals, Inc. Antisense modulation of apolipoprotein B expression
US7888324B2 (en) 2001-08-01 2011-02-15 Genzyme Corporation Antisense modulation of apolipoprotein B expression
AU2002327046B2 (en) 2001-09-24 2007-11-29 One Lambda, Inc. Diagnostic probe detection system
US20030165859A1 (en) * 2001-10-23 2003-09-04 Invitrogen Corporation Primers and methods for the detection and discrimination of nucleic acids
AU2003206869A1 (en) * 2002-02-08 2003-09-02 Evotec Technologies Gmbh Specific multiplex analysis of nucleic acids
AU2003213107A1 (en) 2002-02-15 2003-09-09 Exact Sciences Corporation Methods for analysis of molecular events
JP3752466B2 (ja) * 2002-04-24 2006-03-08 株式会社日立製作所 遺伝子検査方法
US7238476B2 (en) 2002-08-02 2007-07-03 Orchid Cellmark, Inc. Methods and compositions for genotyping
US7192700B2 (en) 2002-12-20 2007-03-20 Orchid Cellmark Inc. Methods and compositions for conducting primer extension and polymorphism detection reactions
AU2003236461B2 (en) * 2002-08-29 2009-05-28 Epigenomics Ag Improved method for bisulfite treatment
US20040121374A1 (en) * 2002-10-02 2004-06-24 Yoshihide Iwaki Method for detecting single nucleotide polymorphisms
US20040259105A1 (en) * 2002-10-03 2004-12-23 Jian-Bing Fan Multiplex nucleic acid analysis using archived or fixed samples
DE60321961D1 (de) * 2002-11-07 2008-08-14 Yoichi Matsubara Verfahren zum genmutationsnachweis
US7511131B2 (en) 2002-11-13 2009-03-31 Genzyme Corporation Antisense modulation of apolipoprotein B expression
JP4786904B2 (ja) 2002-11-27 2011-10-05 セクエノム,インコーポレイティド 配列変化検出及び発見用の断片化をベースとする方法及びシステム
DE602004009038T3 (de) * 2003-01-29 2015-06-25 Roche Diagnostics Gmbh Verbessertes Verfahren zur Behandlung durch Bisulfit
AU2004219662A1 (en) * 2003-03-11 2004-09-23 Gene Check, Inc. RecA-assisted allele specific oligonucleotide extension method
MXPA05010429A (es) 2003-03-31 2005-11-04 Hoffmann La Roche Composiciones y metodos para detectar ciertos flavivirus que incluyen miembros del serogrupo del virus de la encefalitis japonesa.
US20040219532A1 (en) * 2003-04-30 2004-11-04 Sampson Jeffrey R. Internal references measurements
US9045796B2 (en) 2003-06-20 2015-06-02 Illumina, Inc. Methods and compositions for whole genome amplification and genotyping
US20050181394A1 (en) * 2003-06-20 2005-08-18 Illumina, Inc. Methods and compositions for whole genome amplification and genotyping
US20040259100A1 (en) * 2003-06-20 2004-12-23 Illumina, Inc. Methods and compositions for whole genome amplification and genotyping
GB0317592D0 (en) 2003-07-26 2003-08-27 Astrazeneca Ab Method
UY28495A1 (es) * 2003-08-29 2005-03-31 Inst Nac De Tecnologia Agropec Plantas de arroz que tienen una mayor tolerancia a los herbicidas de imidazolinona
US9394565B2 (en) 2003-09-05 2016-07-19 Agena Bioscience, Inc. Allele-specific sequence variation analysis
CA2547743C (fr) 2003-12-02 2011-06-28 F. Hoffmann-La Roche Ag Procede ameliore de traitement au bisulfite
US7129049B2 (en) 2003-12-22 2006-10-31 Regents Of The University Of Minnesota Method of detecting equine glycogen storage disease IV
US7432082B2 (en) * 2004-03-22 2008-10-07 Basf Ag Methods and compositions for analyzing AHASL genes
AU2005230936B2 (en) 2004-03-26 2010-08-05 Agena Bioscience, Inc. Base specific cleavage of methylation-specific amplification products in combination with mass analysis
US20050287558A1 (en) 2004-05-05 2005-12-29 Crooke Rosanne M SNPs of apolipoprotein B and modulation of their expression
US7939251B2 (en) 2004-05-06 2011-05-10 Roche Molecular Systems, Inc. SENP1 as a marker for cancer
US7932026B2 (en) 2004-06-04 2011-04-26 Genentech, Inc. EGFR mutations
WO2006005081A2 (fr) * 2004-06-30 2006-01-12 Applera Corporation Compositions et procedes pour identifier les nucleotides dans des sequences polynucleotidiques
CA2576813A1 (fr) * 2004-07-30 2006-03-09 Basf Agrochemical Products B.V. Plants de tournesol resistant aux herbicides, polynucleotides codant pour des proteines a large sous-unite d'acetohydroxy acide synthase resistant aux herbicides, et methodes d'utilisation
WO2006026654A2 (fr) 2004-08-27 2006-03-09 Exact Sciences Corporation Procede pour detecter une recombinaison
EP1632578A1 (fr) 2004-09-03 2006-03-08 Roche Diagnostics GmbH Méthode pour la décontamination de l' ADN
WO2006047787A2 (fr) 2004-10-27 2006-05-04 Exact Sciences Corporation Methode de surveillance de la progression ou la recurrence d'une maladie
JP2006129811A (ja) * 2004-11-08 2006-05-25 Hitachi Ltd 試料核酸の分析方法、分析装置および分析キット
US20060105348A1 (en) * 2004-11-15 2006-05-18 Lee Jun E Compositions and methods for the detection and discrimination of nucleic acids
US20060275792A1 (en) * 2004-11-15 2006-12-07 Lee Jun E Enhancement of nucleic acid amplification using double-stranded DNA binding proteins
GB0428255D0 (en) 2004-12-23 2005-01-26 Health Prot Agency Detection of nucleic acid mutations
ES2692594T1 (es) * 2005-03-02 2018-12-04 Instituto Nacional De Tecnologia Agropecuaria Plantas de arroz resistentes a herbicidas, polinucleótidos que codifican proteínas de la subunidad grande de la acetohidroxiácido sintasa resistentes a herbicidas y métodos para su uso
GB2424886A (en) 2005-04-04 2006-10-11 Dxs Ltd Polynucleotide primers against epidermal growth factor receptor and method of detecting gene mutations
EP1871796A4 (fr) 2005-04-20 2009-01-14 Auckland Uniservices Ltd Vésiculines
US9777314B2 (en) 2005-04-21 2017-10-03 Esoterix Genetic Laboratories, Llc Analysis of heterogeneous nucleic acid samples
RS54931B1 (sr) * 2005-07-01 2016-10-31 Basf Se Biljke suncokreta otporne na herbicide, polinukleotidi koji kodiraju acetohidroksikiselu sintazu velike podjedinice proteina otpornu na herbicide, i metodi upotrebe
GB0514913D0 (en) * 2005-07-20 2005-08-24 Univ Birmingham Polymorphism
US11111544B2 (en) 2005-07-29 2021-09-07 Natera, Inc. System and method for cleaning noisy genetic data and determining chromosome copy number
AU2007257094B2 (en) 2006-05-05 2012-10-25 Isis Pharmaceuticals, Inc. Compounds and methods for modulating expression of SGLT2
US7759062B2 (en) 2006-06-09 2010-07-20 Third Wave Technologies, Inc. T-structure invasive cleavage assays, consistent nucleic acid dispensing, and low level target nucleic acid detection
KR100812259B1 (ko) * 2006-06-12 2008-03-10 주식회사 씨젠 기지의 서열에 인접한 미지의 dna 서열을 증폭하는 방법
WO2007150069A2 (fr) 2006-06-23 2007-12-27 Myriad Genetics, Inc. Variantes du gène dpyd et leur utilisation
AU2007293280A1 (en) 2006-09-07 2008-03-13 Astrazeneca Ab Method for evaluating patients for treatment with drugs targeting RET receptor tyrosine kinase
CN102016035A (zh) * 2006-11-02 2011-04-13 犹他大学研究基金会 可用于等位基因特异pcr的寡聚核苷酸
UA108733C2 (uk) 2006-12-12 2015-06-10 Толерантна до гербіциду рослина соняшника
US9938641B2 (en) * 2006-12-18 2018-04-10 Fluidigm Corporation Selection of aptamers based on geometry
EP2097448A4 (fr) 2006-12-22 2010-07-21 Univ Utah Res Found Procédé de détection de maladies et états pathologiques oculaires et traitement de ceux-ci
US8314220B2 (en) * 2007-01-26 2012-11-20 Agilent Technologies, Inc. Methods compositions, and kits for detection of microRNA
JP2010522245A (ja) 2007-03-24 2010-07-01 ゲンザイム コーポレイション ヒトアポリポタンパク質bと相補的なアンチセンスオリゴヌクレオチドの投与
US10017827B2 (en) 2007-04-04 2018-07-10 Nidera S.A. Herbicide-resistant sunflower plants with multiple herbicide resistant alleles of AHASL1 and methods of use
EP2076289B1 (fr) 2007-04-13 2014-11-12 Dana-Farber Cancer Institute, Inc. Méthodes de traitement d'un cancer résistant à des agents thérapeutiques anti-erbb
CA2686211C (fr) 2007-05-03 2018-08-21 One Lambda Inc. Procedes de criblage d'interactions de liaisons utilisant des ensembles de microparticules et des sondes uniques
RU2009147281A (ru) 2007-05-21 2011-06-27 Дженентек, Инк. (Us) Способы и композиции для диагностики и лечения волчанки
CN101801992A (zh) * 2007-05-31 2010-08-11 孟山都技术公司 大豆多态性与基因分型方法
WO2008144827A1 (fr) 2007-05-31 2008-12-04 The University Of Queensland Marqueurs de diagnostic pour une spondylarthrite ankylosante et leurs utilisations
EP2185726B1 (fr) 2007-08-06 2014-01-08 Orion Genomics, LLC Nouveaux polymorphismes nucléotidiques uniques et combinaisons de nouveaux polymorphismes connus permettant de déterminer l'expression spécifique d'allèle du gène igf2
AR071243A1 (es) 2007-08-29 2010-06-09 Monsanto Technology Llc Metodos y composiciones para usar plantas haploides en el mapeo genetico de caracteristicas, como resistencia a enfermedades
CA2639416C (fr) 2007-09-11 2019-12-31 F. Hoffmann-La Roche Ag Test de diagnostic pour la susceptibilite aux inhibiteurs de la b-raf kinase
GB2453173A (en) 2007-09-28 2009-04-01 Dxs Ltd Polynucleotide primers
CA2704447A1 (fr) 2007-11-01 2009-05-07 University Of Iowa Research Foundation Prediction d'amd avec snps a l'interieur ou pres de c2, facteur b, plekha1, htra1, prelp ou loc387715
US7958066B2 (en) * 2007-11-02 2011-06-07 Hunch Inc. Interactive machine learning advice facility
WO2009074882A2 (fr) * 2007-11-02 2009-06-18 Luminex Molecular Diagnostics, Inc. Épreuve biologique de détection de cible s'effectuant en une seule étape
JP5188789B2 (ja) * 2007-11-29 2013-04-24 株式会社日立製作所 核酸の定量方法
JP5530185B2 (ja) 2008-02-05 2014-06-25 オリンパス株式会社 核酸検出方法及び核酸検出用キット
CN104388568B (zh) 2008-04-24 2017-04-12 孟山都技术有限公司 鉴定大豆中亚洲大豆锈病抗性数量性状基因座的方法和其组合物
EP2113574A1 (fr) 2008-04-28 2009-11-04 Biotype AG Substances et procédés pour un dosage de profilage à base d'ADN
US8911948B2 (en) * 2008-04-30 2014-12-16 Integrated Dna Technologies, Inc. RNase H-based assays utilizing modified RNA monomers
AU2009242546B2 (en) 2008-04-30 2015-01-22 Integrated Dna Technologies, Inc. RNase-H-based assays utilizing modified RNA monomers
EP2314680B1 (fr) 2008-07-02 2014-10-01 ARKRAY, Inc. Procédé d'amplification d'une séquence d'acides nucléiques cible, procédé de détection de la mutation à l'aide du procédé, et réactifs en vue d'une utilisation dans les procédés
JP5590781B2 (ja) 2008-07-10 2014-09-17 オリンパス株式会社 標的核酸比率推定方法
CN102186996A (zh) * 2008-10-20 2011-09-14 霍夫曼-拉罗奇有限公司 改进的等位基因特异性扩增
EP2186907A1 (fr) 2008-11-11 2010-05-19 Deutsches Primatenzentrum GmbH Variation chromosomique X en tant que marqueur de diagnostic et thérapeutique pour la progression du SIDA
ES2544265T3 (es) 2009-02-11 2015-08-28 Orion Genomics, Llc Combinaciones de polimorfismos para determinar la expresión específica de alelo de IGF2
IL313131A (en) 2009-02-11 2024-07-01 Caris Mpi Inc Molecular characterization of tumors
JP5457222B2 (ja) * 2009-02-25 2014-04-02 エフ.ホフマン−ラ ロシュ アーゲー 小型化ハイスループット核酸分析
US9347092B2 (en) * 2009-02-25 2016-05-24 Roche Molecular System, Inc. Solid support for high-throughput nucleic acid analysis
EP2408796B1 (fr) 2009-03-16 2020-04-22 Ionis Pharmaceuticals, Inc. Ciblage de l'Apolipoprotéine B pour la réduction de l'apolipoprotéine C-III
BRPI1006448B1 (pt) 2009-03-25 2021-08-17 Genentech, Inc Anticorpo antagonista anti-fgfr3, anticorpo monoclonal, polinucleotídeo, vetor, micro­organismo transgênico, método para produção de um anticorpo anti-fgfr3, formulação farmacêutica e usos do anticorpo antagonista anti-fgfr3
WO2010112033A2 (fr) 2009-03-31 2010-10-07 Østjysk Innovation A/S Méthode permettant d'estimer le risque d'avoir ou de développer une sclérose en plaques à l'aide de polymorphismes de séquence dans une région particulière du chromosome x
US20100299773A1 (en) * 2009-05-20 2010-11-25 Monsanto Technology Llc Methods and compositions for selecting an improved plant
CN102686728B (zh) 2009-06-29 2018-09-18 卢米耐克斯公司 具有发夹构象的嵌合引物及其使用方法
BR112012007778A2 (pt) 2009-10-07 2020-08-11 Genentech, Inc. método para identificar lúpus, método para avaliar se um sujeito está em risco de desenvolver lúpus, medicamentos para tratar uma condição de lupus, método e usos de um agente terapêutico.
WO2011056688A2 (fr) 2009-10-27 2011-05-12 Caris Life Sciences, Inc. Profilage moléculaire pour médecine personnalisée
US20110129832A1 (en) * 2009-10-27 2011-06-02 Swift Biosciences, Inc. Polynucleotide Primers and Probes
US8614071B2 (en) 2009-12-11 2013-12-24 Roche Molecular Systems, Inc. Preferential amplification of mRNA over DNA using chemically modified primers
US9238832B2 (en) 2009-12-11 2016-01-19 Roche Molecular Systems, Inc. Allele-specific amplification of nucleic acids
CN102471771B (zh) 2010-01-21 2016-01-20 爱科来株式会社 靶序列的扩增方法、多态性检测方法以及其中使用的试剂
WO2011128096A1 (fr) 2010-04-16 2011-10-20 Roche Diagnostics Gmbh Marqueurs de polymorphisme destinés à prédire la réponse à un traitement par un médicament anticorps monoclonal inhibant les récepteurs de l'interleukine-6
US9340833B2 (en) 2010-04-30 2016-05-17 Arkray, Inc. Method for adjusting amplification efficiency of target polynucleotide
EP2383348B1 (fr) 2010-04-30 2015-03-04 ARKRAY, Inc. Procédé pour le réglage de l'efficacité d'amplification de polynucléotides cibles
GB201008125D0 (en) 2010-05-14 2010-06-30 Biofortuna Ltd Tissue typing assays and kits
US11939634B2 (en) 2010-05-18 2024-03-26 Natera, Inc. Methods for simultaneous amplification of target loci
WO2012071096A2 (fr) 2010-09-03 2012-05-31 The Johns Hopkins University Mutations arid1a et ppp2r1a dans le cancer
WO2012052758A1 (fr) 2010-10-22 2012-04-26 Astrazeneca Ab Biomarqueurs de réponse pour des antagonistes de iap dans des cancers humains
CA2824223A1 (fr) 2011-01-14 2012-07-19 Genefirst Limited Procedes, compositions et trousses pour la determination de la presence/l'absence d'une sequence variante d'acide nucleique
GB201101200D0 (en) 2011-01-24 2011-03-09 King S College Method
JP6153874B2 (ja) 2011-02-09 2017-06-28 ナテラ, インコーポレイテッド 非侵襲的出生前倍数性呼び出しのための方法
WO2012135053A2 (fr) 2011-03-25 2012-10-04 Integrated Dna Technologies, Inc. Essais à base d'arnase h faisant appel à des monomères d'arn modifiés
JP6293655B2 (ja) 2011-04-01 2018-03-14 ジェネンテック, インコーポレイテッド 癌治療に対する感受性を予測するためのバイオマーカー
WO2012149193A2 (fr) 2011-04-29 2012-11-01 Monsanto Technology Llc Marqueurs moléculaires de diagnostic pour des caractères de pureté de lot de graines chez le soja
JP6133275B2 (ja) 2011-05-02 2017-05-24 ボード・オブ・リージェンツ・オブ・ザ・ユニヴァーシティ・オブ・ネブラスカBoard Of Regents Of The University Of Nebraska 有用な特徴を有する植物および関連する方法
HUE044521T2 (hu) 2011-08-31 2019-10-28 Seminis Vegetable Seeds Inc Görögdinnye szilárdságával kapcsolatos eljárások és kompozíciók
SG10201607224PA (en) 2011-08-31 2016-10-28 Hoffmann La Roche Responsiveness to Angiogenesis Inhibitors
RU2014110270A (ru) 2011-08-31 2015-10-10 Ф. Хоффманн-Ля Рош Аг Способ прогнозирования риска гипертензии, связанной с антиангиогенной терапией
US20130078252A1 (en) 2011-09-19 2013-03-28 Genentech, Inc. Combination treatments comprising c-met antagonists and b-raf antagonists
CN108373506A (zh) 2011-10-14 2018-08-07 霍夫曼-拉罗奇有限公司 抗HtrA1抗体及使用方法
WO2013071119A2 (fr) 2011-11-10 2013-05-16 Genentech, Inc Méthodes pour traiter, diagnostiquer et surveiller la maladie d'alzheimer
CN104066852A (zh) 2011-11-23 2014-09-24 霍夫曼-拉罗奇有限公司 对血管发生抑制剂的响应性
SG11201402510TA (en) 2011-11-30 2014-06-27 Genentech Inc Erbb3 mutations in cancer
CN104114714A (zh) 2011-12-14 2014-10-22 阿斯利康(瑞典)有限公司 Gabr-a2诊断
EP2607495A1 (fr) 2011-12-23 2013-06-26 Genomica S.A.U. Procédé de détection des mutations KRAS
US10294529B2 (en) 2012-04-10 2019-05-21 Life Sciences Research Partners Vzw Microsatellite instability markers in detection of cancer
US10633707B2 (en) 2012-04-10 2020-04-28 Vib Vzw Markers for detecting microsatellite instability in cancer and determining synthetic lethality with inhibition of the DNA base excision repair pathway
EP3741871A3 (fr) 2012-04-19 2021-02-17 The Medical College of Wisconsin, Inc. Surveillance hautement sensible faisant appel à la détection d'adn acellulaire
US10077474B2 (en) 2012-05-29 2018-09-18 Abbott Molecular, Inc. Method of designing primers, method of detecting single nucleotide polymorphisms (SNPs), method of distinguishing SNPs, and related primers, detectable oligonucleotides, and kits
EP2711432A1 (fr) 2012-09-21 2014-03-26 Genomica S.A.U. Procédé de détection des mutations de BRAF et PI3K
US10314253B2 (en) 2012-12-04 2019-06-11 Seminis Vegetable Seeds, Inc. Methods and compositions for watermelon sex expression
WO2014130923A2 (fr) 2013-02-25 2014-08-28 Genentech, Inc. Procédés et compositions pour détecter et traiter un mutant d'akt résistant aux médicaments
US10294489B2 (en) 2013-03-15 2019-05-21 Board Of Trustees Of Southern Illinois University Soybean resistant to cyst nematodes
CA2902167A1 (fr) 2013-03-15 2014-09-25 Abbott Molecular Inc. Procede d'amplification et de dosage de variants de gene de fusion d'arn, procede de distinction de ceux-ci et amorces, sondes et trousses s'y rapportant
WO2014149356A1 (fr) 2013-03-15 2014-09-25 Abbott Molecular Inc. Détection de séquences nucléotidiques converties par bisulfite
CN105074009B (zh) 2013-03-19 2017-09-26 凸版印刷株式会社 Egfr抑制剂的敏感性的预测方法
US10059999B2 (en) 2013-06-10 2018-08-28 Monsanto Technology Llc Molecular markers associated with soybean tolerance to low iron growth conditions
US10767188B2 (en) 2013-09-25 2020-09-08 Nutech Ventures Methods and compositions for obtaining useful plant traits
NZ630628A (en) 2013-10-08 2015-04-24 Seminis Vegetable Seeds Inc Methods and compositions for peronospora resistance in spinach
JP2015096049A (ja) 2013-11-15 2015-05-21 凸版印刷株式会社 Vegf阻害剤長期奏功性予測方法
NZ728726A (en) 2013-11-27 2018-09-28 Seminis Vegetable Seeds Inc Disease resistance loci in onion
ES2927871T3 (es) 2014-02-21 2022-11-11 Syngenta Participations Ag Loci genéticos asociados con una mayor fertilidad en el maíz
NZ630710A (en) 2014-02-27 2016-03-31 Seminis Vegetable Seeds Inc Compositions and methods for peronospora resistance in spinach
CA2943405A1 (fr) 2014-03-31 2015-10-08 Debiopharm International Sa Fusions de fgfr
TW201620526A (zh) * 2014-06-17 2016-06-16 愛羅海德研究公司 用於抑制α-1抗胰蛋白酶基因表現之組合物及方法
US10316369B2 (en) 2014-06-27 2019-06-11 Seminis Vegetable Seeds, Inc. Methods and assays for male sterile watermelon
CN113016623A (zh) 2014-09-26 2021-06-25 谱赛科美国股份有限公司 用于甜菊的单核苷酸多态性(snp)标志物
EP3005862A1 (fr) 2014-10-10 2016-04-13 Seminis Vegetable Seeds, Inc. Plants de melon présentant une meilleure tolérance aux maladies
RU2017119185A (ru) 2014-11-05 2018-12-05 Дженентек, Инк. Антитела против fgfr2/3 и способы их применения
US11708608B2 (en) 2014-11-10 2023-07-25 Genentech, Inc. Therapeutic and diagnostic methods for IL-33-mediated disorders
US9909169B2 (en) 2014-12-17 2018-03-06 Roche Molecular Systems, Inc. Allele-specific amplification of nucleic acids using blocking oligonucleotides for wild type suppression
EP3289087B1 (fr) 2015-04-28 2021-02-24 Monsanto Technology LLC Procédés et compositions pour produire des plants de maïs bachytiques
EP3288369A4 (fr) 2015-04-30 2018-09-12 Monsanto Technology LLC Procédés de production de plantes de colza résistantes contre la hernie et compositions associées
EP3294906B1 (fr) 2015-05-11 2024-07-10 Natera, Inc. Procédés pour la détermination de la ploïdie
AU2016308049B2 (en) 2015-08-18 2022-03-17 Monsanto Technology Llc Methods for producing cotton plants with enhanced drought tolerance and compositions thereof
US10448595B2 (en) 2015-09-03 2019-10-22 Seminis Vegetable Seeds, Inc. Downy mildew resistant lettuce plants
WO2017044744A2 (fr) 2015-09-10 2017-03-16 Monsanto Technology Llc Procédés de production de plantes de maïs présentant une résistance au mildiou et compositions associées
WO2017075212A1 (fr) 2015-10-30 2017-05-04 Genentech, Inc. Anticorps anti-htr a1 et méthodes d'utilisation de ceux-ci
CA3006080A1 (fr) 2015-12-18 2017-06-22 Monsanto Technology Llc Procedes de production de plants de mais presentant une resistance a la brulure des feuilles du mais et compositions associees
US10837067B2 (en) 2016-08-11 2020-11-17 Monsanto Technology Llc Methods and compositions for producing corn plants with resistance to late wilt
WO2018035377A1 (fr) * 2016-08-17 2018-02-22 Factor Bioscience Inc. Produits d'acides nucléiques et leurs procédés d'administration
AU2017232187B2 (en) 2016-09-30 2023-11-09 Seminis Vegetable Seeds, Inc. Xanthomonas resistant brassica oleracea plants
EP3535391A4 (fr) * 2016-11-02 2020-05-13 The Medical College of Wisconsin, Inc. Méthodes d'évaluation de risque faisant appel à l'amplification avec mésappariement et à des méthodes statistiques
US11031099B2 (en) 2016-11-09 2021-06-08 Roche Molecular Systems, Inc. Detection of sequence variants
WO2018118808A1 (fr) 2016-12-19 2018-06-28 The Broad Institute, Inc. Méthodes de traitement des troubles du spectre autistique
WO2018170436A1 (fr) 2017-03-16 2018-09-20 Jacobs Farm Del Cabo Basilic à haute tolérance au mildiou
KR20190140952A (ko) 2017-04-24 2019-12-20 제넨테크, 인크. 막관통 및 인접막 도메인에서의 erbb2/her2 돌연변이
CA3063283A1 (fr) 2017-05-17 2018-11-22 Microbio Pty Ltd Methodes et agents pour identifier ou categoriser des microbes en fonction de polymorphismes dans les genes de l'arn ribosomique
JP2020524519A (ja) 2017-06-20 2020-08-20 ザ メディカル カレッジ オブ ウィスコンシン,インコーポレイテッドThe Medical College of Wisconsin, Inc. 全セルフリーdnaによる移植合併症リスクの評価
US11891632B2 (en) 2017-07-12 2024-02-06 Genecast Co., Ltd DNA polymerase with increased gene mutation specificity
US11648551B2 (en) 2017-12-12 2023-05-16 Essenlix Corporation Sample manipulation and assay with rapid temperature change
JP2021506342A (ja) 2017-12-14 2021-02-22 ティーエーアイ ダイアグノスティックス インコーポレイテッドTai Diagnostics,Inc. 移植のための移植片適合性の評価
KR20220098056A (ko) 2018-02-09 2022-07-08 제넨테크, 인크. 비만 세포 매개 염증성 질환에 대한 치료 및 진단 방법
CA3090426A1 (fr) 2018-04-14 2019-10-17 Natera, Inc. Procedes de detection et de surveillance du cancer au moyen d'une detection personnalisee d'adn tumoral circulant
US11268102B2 (en) 2018-05-16 2022-03-08 University Of Florida Research Foundation, Incorporated Compositions and methods for identifying and selecting brachytic locus in solanaceae
EP4369356A3 (fr) 2018-11-30 2024-07-24 Caris MPI, Inc. Profilage moléculaire de nouvelle génération
CA3145881A1 (fr) 2019-01-15 2020-07-23 Seminis Vegetable Seeds, Inc. Plantes de haricot vert possedant une resistance amelioree a sclerotinia sclerotiorum et marqueurs genetiques connexes
US11931674B2 (en) 2019-04-04 2024-03-19 Natera, Inc. Materials and methods for processing blood samples
JPWO2021010326A1 (fr) 2019-07-12 2021-01-21
SG10202008262UA (en) 2019-09-26 2021-04-29 Seminis Vegetable Seeds Inc Lettuce plants having resistance to nasonovia ribisnigri biotype nr:1
JP2023504270A (ja) 2019-12-02 2023-02-02 カリス エムピーアイ インコーポレイテッド 汎がんのプラチナ反応予測子
CA3174986A1 (fr) 2020-03-11 2021-09-16 Seagen Inc. Procedes de traitement des cancers mutants her2 avec le tucatinib
EP4118236A1 (fr) 2020-03-13 2023-01-18 MedImmune Limited Méthodes thérapeutiques pour le traitement de sujets présentant des allèles à risque dans l'il33
AU2021204717A1 (en) 2020-07-15 2022-02-03 Seminis Vegetable Seeds, Inc. Green Bean Plants with Improved Disease Resistance
KR20230078705A (ko) 2020-09-28 2023-06-02 씨젠 인크. 항-her2 항체와 병용된 투카티닙으로 her2 변형에 의해 유도된 고형 종양을 치료하는 방법
EP4247849A2 (fr) 2020-11-17 2023-09-27 Seagen Inc. Méthodes de traitement du cancer au moyen d'une association de tucatinib et d'un anticorps anti-pd-1/anti-pd-l1
US20230193310A1 (en) 2021-12-10 2023-06-22 Seminis Vegetabe Seeds, Inc. Lettuce plants having resistance to downy mildew
US20230404003A1 (en) 2022-06-21 2023-12-21 Seminis Vegetable Seeds, Inc. Novel qtls conferring resistance to cucumber mosaic virus

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8311018D0 (en) * 1983-04-22 1983-05-25 Amersham Int Plc Detecting mutations in dna
US4683195A (en) * 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
US4683202A (en) * 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
CA1284931C (fr) * 1986-03-13 1991-06-18 Henry A. Erlich Procede de detection de variations specifiques de nucleotides et de polymorphismes genetiques dans les acides nucleiques
US4851331A (en) * 1986-05-16 1989-07-25 Allied Corporation Method and kit for polynucleotide assay including primer-dependant DNA polymerase
GB8612087D0 (en) * 1986-05-19 1986-06-25 Ici Plc Hybridisation probes
GB8709652D0 (en) * 1987-04-23 1987-05-28 Williamson R Diagnosis of cystic fibrosis
US4994368A (en) * 1987-07-23 1991-02-19 Syntex (U.S.A.) Inc. Amplification method for polynucleotide assays
JP2634208B2 (ja) * 1987-11-13 1997-07-23 パイオニア・ハイ―ブレツド・インターナシヨナル・インコーポレイテツド 制限断片長多型性分析方法及びその装置
AU613989B2 (en) * 1987-11-24 1991-08-15 Gen-Probe Incorporated Means and method for enhancing nucleic acid hybridization
AU2735988A (en) * 1987-12-21 1989-07-13 Amoco Corporation Target and background capture methods with amplification for affinity assays
US4999290A (en) * 1988-03-31 1991-03-12 The Board Of Regents, The University Of Texas System Detection of genomic abnormalities with unique aberrant gene transcripts
WO1989010414A1 (fr) * 1988-04-28 1989-11-02 Robert Bruce Wallace Polymorphismes (asp) a sequences amplifiees
AU629845B2 (en) * 1988-08-30 1992-10-15 Abbott Laboratories Detection and amplification of target nucleic acid sequences
CA1339731C (fr) * 1988-10-12 1998-03-17 Charles T. Caskey Amplification multiplex de l'dn genomique pour la detection de la detection de la deletion
CA2011818A1 (fr) * 1989-03-17 1990-09-17 Fred T. Oakes Procedes de detection, d'amplification et de purification d'acides nucleiques
WO1990012115A1 (fr) * 1989-03-21 1990-10-18 Collaborative Research, Inc. Test de diagnostic de l'adn utilisant une activite d'exonuclease
CA2013317A1 (fr) * 1989-04-17 1990-10-17 Fred T. Oakes Trousse de diagnostic, amorce et son utilisation pour la replication ou la detection d'acides nucleiques
US5137806A (en) * 1989-12-11 1992-08-11 Board Of Regents, The University Of Texas System Methods and compositions for the detection of sequences in selected DNA molecules
US6004744A (en) * 1991-03-05 1999-12-21 Molecular Tool, Inc. Method for determining nucleotide identity through extension of immobilized primer

Also Published As

Publication number Publication date
PL162338B1 (pl) 1993-10-30
IL89545A (en) 1994-11-11
KR970003151B1 (ko) 1997-03-14
CA1323592C (fr) 1993-10-26
NO174825B (no) 1994-04-05
NZ228266A (en) 1991-05-28
DK175527B1 (da) 2004-11-22
GR3031532T3 (en) 2000-01-31
GR3004442T3 (fr) 1993-03-31
PL278176A1 (en) 1990-02-05
BR8901136A (pt) 1989-10-31
DK118089A (da) 1989-09-11
US5595890A (en) 1997-01-21
IE890739L (en) 1989-09-10
ZW3388A1 (en) 1989-11-22
DK118089D0 (da) 1989-03-10
FI891126A0 (fi) 1989-03-09
AU614584B2 (en) 1991-09-05
YU49789A (sh) 1992-09-07
EP0332435A2 (fr) 1989-09-13
BG87585A (bg) 1993-12-24
IE61148B1 (en) 1994-10-05
HUT52565A (en) 1990-07-28
NO891012D0 (no) 1989-03-09
CN1039618A (zh) 1990-02-14
EP0332435B2 (fr) 1999-10-13
NO174825C (fr) 1994-07-13
JPH0242999A (ja) 1990-02-13
JP2853864B2 (ja) 1999-02-03
FI891126A (fi) 1989-09-11
ES2039294T3 (es) 1993-09-16
EP0332435B1 (fr) 1992-04-22
KR890014750A (ko) 1989-10-25
EP0332435A3 (en) 1990-06-27
AU3124689A (en) 1989-09-14
DE68901285D1 (de) 1992-05-27
NO891012L (no) 1989-09-11
CN1034673C (zh) 1997-04-23
ES2039294T5 (es) 2000-01-16
ATE75262T1 (de) 1992-05-15
PT89980B (pt) 1999-12-31
IL89545A0 (en) 1989-09-10
MY104957A (en) 1994-07-30
PT89980A (pt) 1989-11-10

Similar Documents

Publication Publication Date Title
TNSN89026A1 (fr) Methode de detection de sequences de nucleotides
DE69116993D1 (de) Verfahren zum nukleotidsequenzennachweis mittels technik der sandwich-hybridisierung
GB8729731D0 (en) Hybridization method & probe for detecting nucleic acid sequences
DE68918657D1 (de) Verfahren zum Nachweis spezifischer Nukleinsäuresequenzen.
DK463089A (da) Fremgangsmaade og reagenssaet til detektion af en specifik nucleinsyresekvens i en proeve indeholdende en nucleinsyre
FI900602A0 (fi) Bestaemning.
ES2006377A6 (es) Un metodo de analisis de acidos nucleicos por hibridacion.
ES8507177A1 (es) Un metodo para detectar bacterias en una muestra a ensayar
Vassilev et al. Guide to identification of origins of DNA replication in eukaryotic cell chromosomes
DE3681630D1 (de) Hybridisierungsverfahren und proben dafuer.
IT1244983B (it) Procedimento per rivelare sequenze di acidi nucleici e kit per la sua utilizzazione.
NO922794L (no) Fremgangsmaate for paavisning av nukleinsyrer, anvendelse av en nukleinsyre til immobilisering av nukleinsyrer, samt system for paavisning av nukleinsyrer
ES2145018T3 (es) Deteccion especifica de neisseria gonorrhoeae.
DE69635025D1 (de) Neues verfahren zum nachweis von cryptosporidium
DE3567908D1 (en) Photoimmune detection of dna and rna