DE3681630D1 - Hybridisierungsverfahren und proben dafuer. - Google Patents

Hybridisierungsverfahren und proben dafuer.

Info

Publication number
DE3681630D1
DE3681630D1 DE8686302750T DE3681630T DE3681630D1 DE 3681630 D1 DE3681630 D1 DE 3681630D1 DE 8686302750 T DE8686302750 T DE 8686302750T DE 3681630 T DE3681630 T DE 3681630T DE 3681630 D1 DE3681630 D1 DE 3681630D1
Authority
DE
Germany
Prior art keywords
oligonucleotide
hybridization method
signalling complex
probe
therefor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8686302750T
Other languages
English (en)
Inventor
Francis Joseph Carr
Michael Derek Edge
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Syngenta Ltd
Original Assignee
Imperial Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10577811&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE3681630(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Imperial Chemical Industries Ltd filed Critical Imperial Chemical Industries Ltd
Application granted granted Critical
Publication of DE3681630D1 publication Critical patent/DE3681630D1/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6827Hybridisation assays for detection of mutation or polymorphism
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6816Hybridisation assays characterised by the detection means

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)
  • Peptides Or Proteins (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Electrical Discharge Machining, Electrochemical Machining, And Combined Machining (AREA)
  • Diaphragms For Electromechanical Transducers (AREA)
  • Disintegrating Or Milling (AREA)
  • Inspection Of Paper Currency And Valuable Securities (AREA)
  • Polyoxymethylene Polymers And Polymers With Carbon-To-Carbon Bonds (AREA)
  • Pyridine Compounds (AREA)
DE8686302750T 1985-04-17 1986-04-14 Hybridisierungsverfahren und proben dafuer. Expired - Fee Related DE3681630D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB858509880A GB8509880D0 (en) 1985-04-17 1985-04-17 Testing device

Publications (1)

Publication Number Publication Date
DE3681630D1 true DE3681630D1 (de) 1991-10-31

Family

ID=10577811

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8686302750T Expired - Fee Related DE3681630D1 (de) 1985-04-17 1986-04-14 Hybridisierungsverfahren und proben dafuer.

Country Status (12)

Country Link
EP (1) EP0202758B1 (de)
JP (1) JPS62300A (de)
AT (1) ATE67790T1 (de)
AU (1) AU601361B2 (de)
DE (1) DE3681630D1 (de)
ES (2) ES8802253A1 (de)
GB (1) GB8509880D0 (de)
GR (1) GR861009B (de)
IE (1) IE59038B1 (de)
NZ (1) NZ215835A (de)
PT (1) PT82405B (de)
ZA (1) ZA862583B (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5202231A (en) 1987-04-01 1993-04-13 Drmanac Radoje T Method of sequencing of genomes by hybridization of oligonucleotide probes
US6270961B1 (en) * 1987-04-01 2001-08-07 Hyseq, Inc. Methods and apparatus for DNA sequencing and DNA identification
GB8720394D0 (en) * 1987-08-28 1987-10-07 Ici Plc Nucleotide probes
US4962029A (en) * 1987-10-02 1990-10-09 Cetus Corporation Covalent oligonucleotide-horseradish peroxidase conjugate
WO1989002932A1 (en) * 1987-10-02 1989-04-06 Cetus Corporation A covalent oligonucleotide-horseradish peroxidase conjugate
US5262536A (en) * 1988-09-15 1993-11-16 E. I. Du Pont De Nemours And Company Reagents for the preparation of 5'-tagged oligonucleotides
US4997928A (en) * 1988-09-15 1991-03-05 E. I. Du Pont De Nemours And Company Fluorescent reagents for the preparation of 5'-tagged oligonucleotides
US4908453A (en) * 1989-01-23 1990-03-13 E. I. Du Pont De Nemours And Company Reagents for the preparation of 5'-biotinylated oligonucleotides
ATE193019T1 (de) * 1989-10-13 2000-06-15 Zeneca Ltd Sonden
FR2663040B1 (fr) * 1990-06-11 1995-09-15 Bio Merieux Procede de detection d'une sequence nucleotidique selon la technique d'hybridation sandwich.
US5695926A (en) * 1990-06-11 1997-12-09 Bio Merieux Sandwich hybridization assays using very short capture probes noncovalently bound to a hydrophobic support
WO1995003401A1 (en) * 1993-07-23 1995-02-02 Hyseq, Inc. Method for screening unknown organisms
US20020042048A1 (en) 1997-01-16 2002-04-11 Radoje Drmanac Methods and compositions for detection or quantification of nucleic acid species
US6309824B1 (en) 1997-01-16 2001-10-30 Hyseq, Inc. Methods for analyzing a target nucleic acid using immobilized heterogeneous mixtures of oligonucleotide probes
US6297006B1 (en) 1997-01-16 2001-10-02 Hyseq, Inc. Methods for sequencing repetitive sequences and for determining the order of sequence subfragments
US6355419B1 (en) 1998-04-27 2002-03-12 Hyseq, Inc. Preparation of pools of nucleic acids based on representation in a sample
WO2004089295A2 (en) * 2003-04-01 2004-10-21 Chromagen, Inc. Homogeneous and heterogeneous assay methods using nucleation centers and novel covalent chemistries for the rapid measurement of phosphorylation and de-phosphorylation

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2422956A1 (fr) * 1978-04-13 1979-11-09 Pasteur Institut Procede de detection et de caracterisation d'un acide nucleique ou d'une sequence de celui-ci, et reactif enzymatique pour la mise en oeuvre de ce procede
IL70765A (en) * 1983-01-27 1988-07-31 Enzo Biochem Inc Substrates containing non-radioactive chemically-labeled polynucleotides and methods using them
US4605735A (en) * 1983-02-14 1986-08-12 Wakunaga Seiyaku Kabushiki Kaisha Oligonucleotide derivatives
AU596068B2 (en) * 1983-02-22 1990-04-26 Syngene, Inc. Defined sequence single strand oligonucleotides incorporating reporter groups, process for the chemical synthesis thereof, and nucleosides useful in such synthesis
GB8306426D0 (en) * 1983-03-09 1983-04-13 Malcolm A D B Detecting polynucleotide sequence
ES532041A0 (es) * 1983-05-02 1985-10-01 Enzo Biochem Inc Un metodo para detectar una secuencia seleccionada de acido nucleico en un material biologico.
US4626501A (en) * 1983-09-02 1986-12-02 Integrated Genetics, Inc. Labeled DNA
CA1244786A (en) * 1983-12-20 1988-11-15 Lloyd M. Smith Synthesis of amino-derivitized oligonucleotides
DE3586689T2 (de) * 1984-02-28 1993-04-08 Ortho Diagnostic Systems Inc Diagnose von genmissbildungen durch restriktionskarte-analysierung unter anwendung eines sandwichhybridisierungsformats.

Also Published As

Publication number Publication date
ZA862583B (en) 1987-02-25
GB8509880D0 (en) 1985-05-22
ES8801385A1 (es) 1988-01-01
GR861009B (en) 1986-08-07
IE59038B1 (en) 1993-12-15
AU5599886A (en) 1986-11-06
PT82405B (pt) 1988-08-17
AU601361B2 (en) 1990-09-13
PT82405A (en) 1986-05-01
ES8802253A1 (es) 1988-04-16
ES557326A0 (es) 1988-01-01
IE860889L (en) 1986-10-17
EP0202758B1 (de) 1991-09-25
ATE67790T1 (de) 1991-10-15
NZ215835A (en) 1988-04-29
EP0202758A1 (de) 1986-11-26
JPS62300A (ja) 1987-01-06
ES554059A0 (es) 1988-04-16

Similar Documents

Publication Publication Date Title
DE3681630D1 (de) Hybridisierungsverfahren und proben dafuer.
KR0145908B1 (ko) 핵산 증폭 검출방법
NZ223985A (en) Polynucleotide plm59 (ncib no 12429) and its use as a molecular marker
DE3750198T2 (de) Hybridisierungssonden.
PL278176A1 (en) Method of detecting sequences of nucleotides and sets for carrying out diagnostic tests
DE3578786D1 (de) Als sonden zum nachweis von schaedlichen, in chromosom-dns enthaltenen genen zu verwendende deoxyribonukleinsaeuremolekuele.
ATE136941T1 (de) Nucleinsäuresonden, welche verbesserte molekularschalter enthalten, und analysemethoden und kits, bei welchen die sonden verwendet werden
EP0228075A3 (de) Eukaryotisches genomisches DNA Dot-Blot-Hybridisationsverfahren
KR880700811A (ko) 잡종형성에 의하여 세균 및 기타 살아있는 유기체를 검출하기 위한 올리고 핵삼염 소식자 및 검출 방법
KR870009024A (ko) 폴리뉴클레오티드의 생산 방법
HK109495A (en) Oligonucleotide analogs
KR890701610A (ko) 뉴클레오티드 프로브에 대한 비-뉴클레오티드 연결시약
MY114656A (en) Mycobacteria probes
ATE486965T1 (de) Verfahren zur typisierung und zum nachweis von hbv
Kunkel et al. Mutagenesis in vitro by depurination of ΦX174 DNA
Zhang et al. Study of MICA alleles in 201 African Americans by multiplexed single nucleotide extension (MSNE) typing
ES2069626T3 (es) Sondas de dna especificas de neisseria.
AU7429591A (en) Nucleic acid probes for the detection of giardia lamblia
EP0181635A3 (de) Proben und Verfahren zur Bestimmung chromosomischer Translokationen
EP1705255A3 (de) Diagnostisches Verfahren und Kit zur Bestimmung des Kell-Blutgruppengenotyps
Holbeck et al. Molecular Genetic Analysis of HLA Class II Polymorphism
ES2021482A6 (es) Procedimiento de preparacion de oligonucleotidos sinteticos y de amplificacion genica de sondas moleculares de adn especifico del fenoma macho de rumiantes.

Legal Events

Date Code Title Description
8363 Opposition against the patent
8365 Fully valid after opposition proceedings
8327 Change in the person/name/address of the patent owner

Owner name: ZENECA LTD., LONDON, GB

8339 Ceased/non-payment of the annual fee