ATE136941T1 - Nucleinsäuresonden, welche verbesserte molekularschalter enthalten, und analysemethoden und kits, bei welchen die sonden verwendet werden - Google Patents

Nucleinsäuresonden, welche verbesserte molekularschalter enthalten, und analysemethoden und kits, bei welchen die sonden verwendet werden

Info

Publication number
ATE136941T1
ATE136941T1 AT89911480T AT89911480T ATE136941T1 AT E136941 T1 ATE136941 T1 AT E136941T1 AT 89911480 T AT89911480 T AT 89911480T AT 89911480 T AT89911480 T AT 89911480T AT E136941 T1 ATE136941 T1 AT E136941T1
Authority
AT
Austria
Prior art keywords
probe
kits
acid probes
analysis methods
probes containing
Prior art date
Application number
AT89911480T
Other languages
English (en)
Inventor
Paul M Lizardi
Fred Russell Kramer
Sanjay Tyagi
Cesar Eduardo Guerra
Hilda M Lomeli Buyoli
Barbara C Chu
Gerald F Joyce
Leslie E Orgel
Original Assignee
New York Health Res Inst
Salk Inst For Biological Studi
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by New York Health Res Inst, Salk Inst For Biological Studi filed Critical New York Health Res Inst
Application granted granted Critical
Publication of ATE136941T1 publication Critical patent/ATE136941T1/de

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6867—Replicase-based amplification, e.g. using Q-beta replicase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • C12Q1/682—Signal amplification
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
    • Y10T436/142222—Hetero-O [e.g., ascorbic acid, etc.]
    • Y10T436/143333—Saccharide [e.g., DNA, etc.]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
AT89911480T 1988-09-30 1989-09-29 Nucleinsäuresonden, welche verbesserte molekularschalter enthalten, und analysemethoden und kits, bei welchen die sonden verwendet werden ATE136941T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/251,696 US5118801A (en) 1988-09-30 1988-09-30 Nucleic acid process containing improved molecular switch

Publications (1)

Publication Number Publication Date
ATE136941T1 true ATE136941T1 (de) 1996-05-15

Family

ID=22953028

Family Applications (1)

Application Number Title Priority Date Filing Date
AT89911480T ATE136941T1 (de) 1988-09-30 1989-09-29 Nucleinsäuresonden, welche verbesserte molekularschalter enthalten, und analysemethoden und kits, bei welchen die sonden verwendet werden

Country Status (10)

Country Link
US (2) US5118801A (de)
EP (1) EP0436644B1 (de)
JP (1) JP2806455B2 (de)
AT (1) ATE136941T1 (de)
AU (1) AU647376B2 (de)
DE (1) DE68926302T2 (de)
DK (1) DK56091A (de)
ES (1) ES2023290A6 (de)
FI (1) FI911536A0 (de)
WO (1) WO1990003446A1 (de)

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US5118801A (en) 1992-06-02
EP0436644B1 (de) 1996-04-17
WO1990003446A1 (en) 1990-04-05
DE68926302D1 (de) 1996-05-23
JPH07508398A (ja) 1995-09-21
EP0436644A1 (de) 1991-07-17
DK56091A (da) 1991-05-30
FI911536A0 (fi) 1991-03-28
AU647376B2 (en) 1994-03-24
US5312728A (en) 1994-05-17
AU4346689A (en) 1990-04-18
DK56091D0 (da) 1991-03-27
ES2023290A6 (es) 1992-01-01
JP2806455B2 (ja) 1998-09-30

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