AU6180190A - Fast process for detecting and/or identifying a single base on a nucleic acid sequence and its applications - Google Patents

Fast process for detecting and/or identifying a single base on a nucleic acid sequence and its applications

Info

Publication number
AU6180190A
AU6180190A AU61801/90A AU6180190A AU6180190A AU 6180190 A AU6180190 A AU 6180190A AU 61801/90 A AU61801/90 A AU 61801/90A AU 6180190 A AU6180190 A AU 6180190A AU 6180190 A AU6180190 A AU 6180190A
Authority
AU
Australia
Prior art keywords
identifying
applications
detecting
nucleic acid
acid sequence
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU61801/90A
Inventor
Daniel Cohen
Frederic Dufau
Frederic Ginot
Jean Hache
Marc Jeanpierre
Marie-Christine Martinez
Brigitte Roussel
Agnes Troton
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bertin Technologies SAS
Original Assignee
Bertin et Cie SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bertin et Cie SA filed Critical Bertin et Cie SA
Publication of AU6180190A publication Critical patent/AU6180190A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6858—Allele-specific amplification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869—Methods for sequencing

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)

Abstract

The feature of this process is that: (1) the sequence on which the base to be identified is located is made hybrid with a nucleotide of adequate length; (2) the synthesis of the complementary strand of the hybrid obtained in (1) is started, said nucleotide acting as a trigger, in the presence of: a polymerase without 3'5' exonucleasis action; and at least one modified nucleotide base; (3) the incorporated blocking nucleotide base is detected by any suitable means. Application: diagnosis of genetic diseases.
AU61801/90A 1989-08-11 1990-08-02 Fast process for detecting and/or identifying a single base on a nucleic acid sequence and its applications Abandoned AU6180190A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8910802A FR2650840B1 (en) 1989-08-11 1989-08-11 RAPID DETECTION AND / OR IDENTIFICATION OF A SINGLE BASED ON A NUCLEIC ACID SEQUENCE, AND ITS APPLICATIONS
FR8910802 1989-08-11

Publications (1)

Publication Number Publication Date
AU6180190A true AU6180190A (en) 1991-03-11

Family

ID=9384656

Family Applications (1)

Application Number Title Priority Date Filing Date
AU61801/90A Abandoned AU6180190A (en) 1989-08-11 1990-08-02 Fast process for detecting and/or identifying a single base on a nucleic acid sequence and its applications

Country Status (8)

Country Link
EP (1) EP0412883B1 (en)
JP (1) JPH04502862A (en)
AT (1) ATE145248T1 (en)
AU (1) AU6180190A (en)
CA (1) CA2038932A1 (en)
DE (1) DE69029105T2 (en)
FR (1) FR2650840B1 (en)
WO (1) WO1991002087A1 (en)

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Also Published As

Publication number Publication date
WO1991002087A1 (en) 1991-02-21
EP0412883B1 (en) 1996-11-13
JPH04502862A (en) 1992-05-28
FR2650840B1 (en) 1991-11-29
DE69029105D1 (en) 1996-12-19
CA2038932A1 (en) 1991-02-12
FR2650840A1 (en) 1991-02-15
ATE145248T1 (en) 1996-11-15
DE69029105T2 (en) 1997-04-03
EP0412883A1 (en) 1991-02-13

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