ATE233826T1 - Verbesserte erkennung von spezifischen nukleinsäuren - Google Patents
Verbesserte erkennung von spezifischen nukleinsäurenInfo
- Publication number
- ATE233826T1 ATE233826T1 AT97921072T AT97921072T ATE233826T1 AT E233826 T1 ATE233826 T1 AT E233826T1 AT 97921072 T AT97921072 T AT 97921072T AT 97921072 T AT97921072 T AT 97921072T AT E233826 T1 ATE233826 T1 AT E233826T1
- Authority
- AT
- Austria
- Prior art keywords
- nucleic acids
- specific nucleic
- improved detection
- target
- sequence
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
- C12Q1/6823—Release of bound markers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Analytical Chemistry (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE9601676A SE9601676D0 (sv) | 1996-04-30 | 1996-04-30 | Improved probing of specific mucleic acids |
PCT/SE1997/000737 WO1997041254A1 (en) | 1996-04-30 | 1997-04-30 | Improved probing of specific nucleic acids |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE233826T1 true ATE233826T1 (de) | 2003-03-15 |
Family
ID=20402429
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT97921072T ATE233826T1 (de) | 1996-04-30 | 1997-04-30 | Verbesserte erkennung von spezifischen nukleinsäuren |
Country Status (8)
Country | Link |
---|---|
US (2) | US20010007742A1 (de) |
EP (1) | EP0951565B1 (de) |
JP (1) | JP2000508920A (de) |
AT (1) | ATE233826T1 (de) |
CA (1) | CA2252817C (de) |
DE (1) | DE69719557T2 (de) |
SE (1) | SE9601676D0 (de) |
WO (1) | WO1997041254A1 (de) |
Families Citing this family (72)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6261808B1 (en) * | 1992-08-04 | 2001-07-17 | Replicon, Inc. | Amplification of nucleic acid molecules via circular replicons |
WO1994003624A1 (en) * | 1992-08-04 | 1994-02-17 | Auerbach Jeffrey I | Methods for the isothermal amplification of nucleic acid molecules |
AU2003295745A1 (en) * | 2002-11-19 | 2004-06-15 | Applera Corporation | Polynucleotide sequence detection assays |
US20060141475A1 (en) * | 2002-11-19 | 2006-06-29 | Applera Corporation | Polynucleotide sequence detection assays and analysis |
DE602004028478D1 (de) | 2003-06-17 | 2010-09-16 | Human Genetic Signatures Pty | Verfahren zur genomamplifikation |
DE602004018801D1 (de) | 2003-09-04 | 2009-02-12 | Human Genetic Signatures Pty | Nukleinsäurenachweistest |
US8168777B2 (en) | 2004-04-29 | 2012-05-01 | Human Genetic Signatures Pty. Ltd. | Bisulphite reagent treatment of nucleic acid |
EP1756307A1 (de) * | 2004-05-20 | 2007-02-28 | Trillion Genomics Limited | Verwendung massenmarkierter sonden zum nachweis von zielnukleinsäuren mittels massenspektrometrie |
EP1794173B1 (de) | 2004-09-10 | 2010-08-04 | Human Genetic Signatures PTY Ltd | Amplifikationsblocker umfassend interkalierende nukleinsäuren (ina) enthaltend interkalierende pseudonukleotide (ipn) |
DK1828411T3 (da) | 2004-12-03 | 2013-02-18 | Human Genetic Signatures Pty | Fremgangsmåde til forenkling af mikrobielle nukleinsyrer ved kemisk modifikation af cytosiner |
JP2008541705A (ja) | 2005-05-26 | 2008-11-27 | ヒューマン ジェネティック シグネチャーズ ピーティーワイ リミテッド | 非標準塩基を含むプライマーを使用する等温鎖置換増幅 |
WO2007030882A1 (en) | 2005-09-14 | 2007-03-22 | Human Genetic Signatures Pty Ltd | Assay for a health state |
EP1879377A3 (de) * | 2006-07-13 | 2010-06-16 | Panasonic Corporation | Tragbare Vorrichtung |
WO2009067743A1 (en) | 2007-11-27 | 2009-06-04 | Human Genetic Signatures Pty Ltd | Enzymes for amplification and copying bisulphite modified nucleic acids |
WO2009121021A1 (en) * | 2008-03-28 | 2009-10-01 | Life Technologies Corporation | Degradable arrays for preventing reuse |
US20110159499A1 (en) * | 2009-11-25 | 2011-06-30 | Quantalife, Inc. | Methods and compositions for detecting genetic material |
US9127312B2 (en) | 2011-02-09 | 2015-09-08 | Bio-Rad Laboratories, Inc. | Analysis of nucleic acids |
SG177252A1 (en) * | 2008-12-01 | 2012-03-29 | Lab Corp America Holdings | METHODS AND ASSAYS FOR MEASURING p95 AND/OR p95 IN A SAMPLE AND ANTIBODIES SPECIFIC FOR p95 |
CA2749817A1 (en) * | 2009-01-15 | 2010-07-22 | Laboratory Corporation Of America Holdings | Methods of determining patient response by measurement of her-2 expression |
ES2535723T3 (es) | 2009-01-15 | 2015-05-14 | Laboratory Corporation Of America Holdings | Métodos de determinación de la respuesta del paciente mediante la medición de Her-3 |
CA2760439A1 (en) | 2009-04-30 | 2010-11-04 | Good Start Genetics, Inc. | Methods and compositions for evaluating genetic markers |
US12129514B2 (en) | 2009-04-30 | 2024-10-29 | Molecular Loop Biosolutions, Llc | Methods and compositions for evaluating genetic markers |
US9163281B2 (en) | 2010-12-23 | 2015-10-20 | Good Start Genetics, Inc. | Methods for maintaining the integrity and identification of a nucleic acid template in a multiplex sequencing reaction |
US9556473B2 (en) | 2011-02-15 | 2017-01-31 | Leica Biosystems Newcastle Ltd | Methods for identifying nucleic acid sequences |
AU2012219132B2 (en) | 2011-02-15 | 2016-05-12 | Mats Nilsson Bernitz | Method for localized in situ detection of mRNA |
US8759036B2 (en) | 2011-03-21 | 2014-06-24 | Affymetrix, Inc. | Methods for synthesizing pools of probes |
US8932819B2 (en) | 2011-07-06 | 2015-01-13 | Affymetrix, Inc. | Assays for affinity profiling of nucleic acid binding proteins |
ES2613743T3 (es) | 2011-09-07 | 2017-05-25 | Human Genetic Signatures Pty Ltd | Ensayo de detección molecular |
US9228233B2 (en) | 2011-10-17 | 2016-01-05 | Good Start Genetics, Inc. | Analysis methods |
US8209130B1 (en) | 2012-04-04 | 2012-06-26 | Good Start Genetics, Inc. | Sequence assembly |
US8812422B2 (en) | 2012-04-09 | 2014-08-19 | Good Start Genetics, Inc. | Variant database |
US10227635B2 (en) | 2012-04-16 | 2019-03-12 | Molecular Loop Biosolutions, Llc | Capture reactions |
US10114015B2 (en) | 2013-03-13 | 2018-10-30 | Meso Scale Technologies, Llc. | Assay methods |
KR20230169418A (ko) | 2013-03-13 | 2023-12-15 | 메소 스케일 테크놀러지즈, 엘엘시 | 개선된 분석 방법 |
WO2014152421A1 (en) | 2013-03-14 | 2014-09-25 | Good Start Genetics, Inc. | Methods for analyzing nucleic acids |
KR102134168B1 (ko) | 2013-03-15 | 2020-07-15 | 루브리졸 어드밴스드 머티어리얼스, 인코포레이티드 | 중금속이 없는 씨피브이씨 조성물 |
WO2014197377A2 (en) | 2013-06-03 | 2014-12-11 | Good Start Genetics, Inc. | Methods and systems for storing sequence read data |
WO2015013681A1 (en) | 2013-07-25 | 2015-01-29 | Bio-Rad Laboratories, Inc. | Genetic assays |
WO2015057565A1 (en) | 2013-10-18 | 2015-04-23 | Good Start Genetics, Inc. | Methods for assessing a genomic region of a subject |
US10851414B2 (en) | 2013-10-18 | 2020-12-01 | Good Start Genetics, Inc. | Methods for determining carrier status |
WO2015175530A1 (en) | 2014-05-12 | 2015-11-19 | Gore Athurva | Methods for detecting aneuploidy |
CN106796218B (zh) | 2014-05-15 | 2020-10-13 | 中尺度技术有限责任公司 | 改进的测定方法 |
AU2015273443B2 (en) | 2014-06-13 | 2021-03-04 | Q-Linea Ab | Method for detecting and characterising a microorganism |
WO2016040446A1 (en) | 2014-09-10 | 2016-03-17 | Good Start Genetics, Inc. | Methods for selectively suppressing non-target sequences |
JP2017536087A (ja) | 2014-09-24 | 2017-12-07 | グッド スタート ジェネティクス, インコーポレイテッド | 遺伝子アッセイのロバストネスを増大させるためのプロセス制御 |
WO2016065207A1 (en) * | 2014-10-23 | 2016-04-28 | Ricardo Mancebo | Reagents and methods for isothermal chain reaction |
EP3271480B8 (de) | 2015-01-06 | 2022-09-28 | Molecular Loop Biosciences, Inc. | Abtastung auf strukturelle varianten |
GB201507026D0 (en) | 2015-04-24 | 2015-06-10 | Linea Ab Q | Medical sample transportation container |
CN108350500A (zh) | 2015-07-29 | 2018-07-31 | 普罗格尼迪公司 | 用于检测染色体异常的核酸和方法 |
CN108779487A (zh) | 2015-11-16 | 2018-11-09 | 普罗格尼迪公司 | 用于检测甲基化状态的核酸和方法 |
GB2554767A (en) | 2016-04-21 | 2018-04-11 | Q Linea Ab | Detecting and characterising a microorganism |
JP2020514746A (ja) | 2016-12-01 | 2020-05-21 | ノーティラス バイオテクノロジー インコーポレイテッド | タンパク質をアッセイする方法 |
EP3601610A1 (de) | 2017-03-30 | 2020-02-05 | Pioneer Hi-Bred International, Inc. | Verfahren zur identifizierung und charakterisierung von geneditierungsvariationen in nukleinsäuren |
AU2019247652A1 (en) | 2018-04-02 | 2020-10-15 | Enumera Molecular, Inc. | Methods, systems, and compositions for counting nucleic acid molecules |
CA3132154A1 (en) | 2019-03-01 | 2020-09-10 | Meso Scale Technologies, Llc. | Electrochemiluminescent labeled probes for use in immunoassay methods, methods using such and kits comprising same |
WO2020206170A1 (en) | 2019-04-02 | 2020-10-08 | Progenity, Inc. | Methods, systems, and compositions for counting nucleic acid molecules |
EP4069731A4 (de) | 2019-12-03 | 2024-05-29 | Alamar Biosciences, Inc. | Nukleinsäure-gekoppelter immun-sandwich-assay (nulisa) |
EP4231174A3 (de) | 2020-06-11 | 2023-11-01 | Nautilus Subsidiary, Inc. | Verfahren und syteme zur rechnerischen decodierung biologischer, chemischer und physikalischer einheiten |
EP4214243A1 (de) | 2020-09-21 | 2023-07-26 | Progenity, Inc. | Zusammensetzungen und verfahren zur isolierung von zellfreier dna |
AU2022210423A1 (en) | 2021-01-20 | 2023-07-06 | Nautilus Subsidiary, Inc. | Methods for biomolecule quantitation |
WO2022159663A1 (en) | 2021-01-21 | 2022-07-28 | Nautilus Biotechnology, Inc. | Systems and methods for biomolecule preparation |
EP4305419A1 (de) | 2021-03-11 | 2024-01-17 | Nautilus Subsidiary, Inc. | Systeme und verfahren zur biomolekülretention |
EP4405683A1 (de) | 2021-09-22 | 2024-07-31 | Nautilus Subsidiary, Inc. | Verfahren und systeme zur bestimmung von polypeptidinteraktionen |
WO2023081728A1 (en) | 2021-11-03 | 2023-05-11 | Nautilus Biotechnology, Inc. | Systems and methods for surface structuring |
WO2023192917A1 (en) | 2022-03-29 | 2023-10-05 | Nautilus Subsidiary, Inc. | Integrated arrays for single-analyte processes |
US20230360732A1 (en) | 2022-04-25 | 2023-11-09 | Nautilus Subsidiary, Inc. | Systems and methods for assessing and improving the quality of multiplex molecular assays |
WO2023250364A1 (en) | 2022-06-21 | 2023-12-28 | Nautilus Subsidiary, Inc. | Method for detecting analytes at sites of optically non-resolvable distances |
US20240094215A1 (en) | 2022-09-15 | 2024-03-21 | Nautilus Subsidiary, Inc. | Characterizing accessibility of macromolecule structures |
WO2024073599A1 (en) | 2022-09-29 | 2024-04-04 | Nautilus Subsidiary, Inc. | Preparation of array surfaces for single-analyte processes |
WO2024124073A1 (en) | 2022-12-09 | 2024-06-13 | Nautilus Subsidiary, Inc. | A method comprising performing on a single-analyte array at least 50 cycles of a process |
WO2024130000A1 (en) | 2022-12-15 | 2024-06-20 | Nautilus Subsidiary, Inc. | Inhibition of photon phenomena on single molecule arrays |
WO2024206122A1 (en) | 2023-03-24 | 2024-10-03 | Nautilus Subsidiary, Inc. | Improved transfer of nanoparticles to array surfaces |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5124246A (en) * | 1987-10-15 | 1992-06-23 | Chiron Corporation | Nucleic acid multimers and amplified nucleic acid hybridization assays using same |
US5427930A (en) * | 1990-01-26 | 1995-06-27 | Abbott Laboratories | Amplification of target nucleic acids using gap filling ligase chain reaction |
SE9400522D0 (sv) * | 1994-02-16 | 1994-02-16 | Ulf Landegren | Method and reagent for detecting specific nucleotide sequences |
US5643724A (en) * | 1994-06-06 | 1997-07-01 | Roche Molecular Systems, Inc. | Methods and reagents for Glycophorin A typing |
GB9414934D0 (en) * | 1994-07-25 | 1994-09-14 | Raggio Italgene Spa | Method and reagents for the detection of target nuceic acid sequences |
EP0843735B2 (de) | 1995-07-11 | 2006-12-27 | Forfas (trading as Bioresearch Ireland) | Glycosylase verwendende detektion von bestimmten nukleinsäuresequenzen |
-
1996
- 1996-04-30 SE SE9601676A patent/SE9601676D0/xx unknown
-
1997
- 1997-04-30 JP JP9538820A patent/JP2000508920A/ja not_active Ceased
- 1997-04-30 CA CA002252817A patent/CA2252817C/en not_active Expired - Lifetime
- 1997-04-30 AT AT97921072T patent/ATE233826T1/de not_active IP Right Cessation
- 1997-04-30 WO PCT/SE1997/000737 patent/WO1997041254A1/en active IP Right Grant
- 1997-04-30 DE DE69719557T patent/DE69719557T2/de not_active Expired - Lifetime
- 1997-04-30 US US09/171,935 patent/US20010007742A1/en not_active Abandoned
- 1997-04-30 EP EP97921072A patent/EP0951565B1/de not_active Expired - Lifetime
-
2001
- 2001-12-31 US US10/029,913 patent/US7351528B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
CA2252817C (en) | 2009-07-07 |
JP2000508920A (ja) | 2000-07-18 |
US7351528B2 (en) | 2008-04-01 |
CA2252817A1 (en) | 1997-11-06 |
EP0951565B1 (de) | 2003-03-05 |
DE69719557D1 (de) | 2003-04-10 |
WO1997041254A1 (en) | 1997-11-06 |
US20010007742A1 (en) | 2001-07-12 |
DE69719557T2 (de) | 2004-02-26 |
SE9601676D0 (sv) | 1996-04-30 |
US20020102592A1 (en) | 2002-08-01 |
EP0951565A1 (de) | 1999-10-27 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |