DE69719557D1 - Verbesserte erkennung von spezifischen nukleinsäuren - Google Patents

Verbesserte erkennung von spezifischen nukleinsäuren

Info

Publication number
DE69719557D1
DE69719557D1 DE69719557T DE69719557T DE69719557D1 DE 69719557 D1 DE69719557 D1 DE 69719557D1 DE 69719557 T DE69719557 T DE 69719557T DE 69719557 T DE69719557 T DE 69719557T DE 69719557 D1 DE69719557 D1 DE 69719557D1
Authority
DE
Germany
Prior art keywords
nucleic acids
specific nucleic
improved detection
target
sequence
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69719557T
Other languages
English (en)
Other versions
DE69719557T2 (de
Inventor
Ulf Landegren
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Landegren Gene Technology Uppsala Se AB
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of DE69719557D1 publication Critical patent/DE69719557D1/de
Application granted granted Critical
Publication of DE69719557T2 publication Critical patent/DE69719557T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6816Hybridisation assays characterised by the detection means
    • C12Q1/6823Release of bound markers
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6827Hybridisation assays for detection of mutation or polymorphism
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6834Enzymatic or biochemical coupling of nucleic acids to a solid phase

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
DE69719557T 1996-04-30 1997-04-30 Verbesserte erkennung von spezifischen nukleinsäuren Expired - Lifetime DE69719557T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE9601676 1996-04-30
SE9601676A SE9601676D0 (sv) 1996-04-30 1996-04-30 Improved probing of specific mucleic acids
PCT/SE1997/000737 WO1997041254A1 (en) 1996-04-30 1997-04-30 Improved probing of specific nucleic acids

Publications (2)

Publication Number Publication Date
DE69719557D1 true DE69719557D1 (de) 2003-04-10
DE69719557T2 DE69719557T2 (de) 2004-02-26

Family

ID=20402429

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69719557T Expired - Lifetime DE69719557T2 (de) 1996-04-30 1997-04-30 Verbesserte erkennung von spezifischen nukleinsäuren

Country Status (8)

Country Link
US (2) US20010007742A1 (de)
EP (1) EP0951565B1 (de)
JP (1) JP2000508920A (de)
AT (1) ATE233826T1 (de)
CA (1) CA2252817C (de)
DE (1) DE69719557T2 (de)
SE (1) SE9601676D0 (de)
WO (1) WO1997041254A1 (de)

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ES2399054T3 (es) 2004-12-03 2013-03-25 Human Genetic Signatures Pty Ltd Métodos para simplificar ácidos nucleicos microbianos mediante modificación química de citosinas
EP1883707B1 (de) 2005-05-26 2014-04-09 Human Genetic Signatures PTY Ltd Isothermische strangverdrängungsamplifikation unter verwendung von eine nichtreguläre base enthaltenden primern
CA2621932A1 (en) 2005-09-14 2007-03-22 Human Genetic Signatures Pty Ltd Assay for hpv and methylated genomic dna targets to screen for cervical cancer
EP1879377A3 (de) * 2006-07-13 2010-06-16 Panasonic Corporation Tragbare Vorrichtung
JP5431351B2 (ja) 2007-11-27 2014-03-05 ヒューマン ジェネティック シグネチャーズ ピーティーワイ リミテッド バイサルファイト修飾された核酸を増幅およびコピーするための酵素
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SG172983A1 (en) 2009-01-15 2011-08-29 Lab Corp America Holdings Methods of determining patient response by measurement of her-3
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JP2013511991A (ja) * 2009-11-25 2013-04-11 クアンタライフ, インコーポレイテッド 遺伝子材料を検出する方法および組成物
US9163281B2 (en) 2010-12-23 2015-10-20 Good Start Genetics, Inc. Methods for maintaining the integrity and identification of a nucleic acid template in a multiplex sequencing reaction
EP3483285B1 (de) 2011-02-09 2021-07-14 Bio-Rad Laboratories, Inc. Analyse von nukleinsäuren
AU2012219132B2 (en) 2011-02-15 2016-05-12 Mats Nilsson Bernitz Method for localized in situ detection of mRNA
US9556473B2 (en) 2011-02-15 2017-01-31 Leica Biosystems Newcastle Ltd Methods for identifying nucleic acid sequences
US8759036B2 (en) 2011-03-21 2014-06-24 Affymetrix, Inc. Methods for synthesizing pools of probes
US8932819B2 (en) 2011-07-06 2015-01-13 Affymetrix, Inc. Assays for affinity profiling of nucleic acid binding proteins
WO2013033749A1 (en) 2011-09-07 2013-03-14 Human Genetic Signatures Pty Ltd Molecular detection assay
EP2768983A4 (de) 2011-10-17 2015-06-03 Good Start Genetics Inc Analyseverfahren
US8209130B1 (en) 2012-04-04 2012-06-26 Good Start Genetics, Inc. Sequence assembly
US8812422B2 (en) 2012-04-09 2014-08-19 Good Start Genetics, Inc. Variant database
US10227635B2 (en) 2012-04-16 2019-03-12 Molecular Loop Biosolutions, Llc Capture reactions
US10114015B2 (en) 2013-03-13 2018-10-30 Meso Scale Technologies, Llc. Assay methods
CN110308272B (zh) 2013-03-13 2023-09-12 中尺度技术有限责任公司 改进的测定方法
WO2014152421A1 (en) 2013-03-14 2014-09-25 Good Start Genetics, Inc. Methods for analyzing nucleic acids
KR102134168B1 (ko) 2013-03-15 2020-07-15 루브리졸 어드밴스드 머티어리얼스, 인코포레이티드 중금속이 없는 씨피브이씨 조성물
EP3005200A2 (de) 2013-06-03 2016-04-13 Good Start Genetics, Inc. Verfahren und systeme zur speicherung von sequenzlesedaten
CN105555972B (zh) 2013-07-25 2020-07-31 伯乐生命医学产品有限公司 遗传测定
US10851414B2 (en) 2013-10-18 2020-12-01 Good Start Genetics, Inc. Methods for determining carrier status
US11041203B2 (en) 2013-10-18 2021-06-22 Molecular Loop Biosolutions, Inc. Methods for assessing a genomic region of a subject
WO2015175530A1 (en) 2014-05-12 2015-11-19 Gore Athurva Methods for detecting aneuploidy
KR20230022268A (ko) 2014-05-15 2023-02-14 메소 스케일 테크놀러지즈, 엘엘시 개선된 분석 방법
EP3074539B1 (de) 2014-06-13 2018-01-10 Q-Linea AB Verfahren für den nachweis und die charakterisierung eines mikroorganismus
WO2016040446A1 (en) 2014-09-10 2016-03-17 Good Start Genetics, Inc. Methods for selectively suppressing non-target sequences
EP3224595A4 (de) 2014-09-24 2018-06-13 Good Start Genetics, Inc. Prozesssteuerung für erhöhte robustheit von genetischen assays
EP3209798B1 (de) 2014-10-23 2022-07-27 Ricardo Mancebo Reagenzien und verfahren für eine isothermische kettenreaktion
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US20170298427A1 (en) 2015-11-16 2017-10-19 Progenity, Inc. Nucleic acids and methods for detecting methylation status
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EP3931201A1 (de) 2019-03-01 2022-01-05 Meso Scale Technologies, LLC Elektrochemilumineszente markierte sonden zur verwendung in immunoassay-verfahren, verfahren mit verwendung davon und kits damit
WO2020206170A1 (en) 2019-04-02 2020-10-08 Progenity, Inc. Methods, systems, and compositions for counting nucleic acid molecules
AU2021288692A1 (en) 2020-06-11 2023-02-02 Nautilus Subsidiary, Inc. Methods and systems for computational decoding of biological, chemical, and physical entities
EP4214243A1 (de) 2020-09-21 2023-07-26 Progenity, Inc. Zusammensetzungen und verfahren zur isolierung von zellfreier dna
EP4281774A2 (de) 2021-01-20 2023-11-29 Nautilus Subsidiary, Inc. Verfahren zur quantifizierung von biomolekülen
AU2022209365A1 (en) 2021-01-21 2023-07-20 Nautilus Subsidiary, Inc. Systems and methods for biomolecule preparation
CA3209038A1 (en) 2021-03-11 2022-09-15 Tural AKSEL Systems and methods for biomolecule retention
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Also Published As

Publication number Publication date
US20020102592A1 (en) 2002-08-01
JP2000508920A (ja) 2000-07-18
US7351528B2 (en) 2008-04-01
CA2252817C (en) 2009-07-07
CA2252817A1 (en) 1997-11-06
DE69719557T2 (de) 2004-02-26
EP0951565B1 (de) 2003-03-05
US20010007742A1 (en) 2001-07-12
ATE233826T1 (de) 2003-03-15
SE9601676D0 (sv) 1996-04-30
WO1997041254A1 (en) 1997-11-06
EP0951565A1 (de) 1999-10-27

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Legal Events

Date Code Title Description
8327 Change in the person/name/address of the patent owner

Owner name: LANDEGREN GENE TECHNOLOGY AB, UPPSALA, SE

8381 Inventor (new situation)

Inventor name: LANDEGREN, ULF, 756 45 UPPSALA, SE

8364 No opposition during term of opposition