DE69719557D1 - Verbesserte erkennung von spezifischen nukleinsäuren - Google Patents
Verbesserte erkennung von spezifischen nukleinsäurenInfo
- Publication number
- DE69719557D1 DE69719557D1 DE69719557T DE69719557T DE69719557D1 DE 69719557 D1 DE69719557 D1 DE 69719557D1 DE 69719557 T DE69719557 T DE 69719557T DE 69719557 T DE69719557 T DE 69719557T DE 69719557 D1 DE69719557 D1 DE 69719557D1
- Authority
- DE
- Germany
- Prior art keywords
- nucleic acids
- specific nucleic
- improved detection
- target
- sequence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 150000007523 nucleic acids Chemical class 0.000 title abstract 3
- 102000039446 nucleic acids Human genes 0.000 title abstract 3
- 108020004707 nucleic acids Proteins 0.000 title abstract 3
- 238000001514 detection method Methods 0.000 title 1
- 239000000523 sample Substances 0.000 abstract 2
- 230000001419 dependent effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
- C12Q1/6823—Release of bound markers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Analytical Chemistry (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE9601676 | 1996-04-30 | ||
SE9601676A SE9601676D0 (sv) | 1996-04-30 | 1996-04-30 | Improved probing of specific mucleic acids |
PCT/SE1997/000737 WO1997041254A1 (en) | 1996-04-30 | 1997-04-30 | Improved probing of specific nucleic acids |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69719557D1 true DE69719557D1 (de) | 2003-04-10 |
DE69719557T2 DE69719557T2 (de) | 2004-02-26 |
Family
ID=20402429
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69719557T Expired - Lifetime DE69719557T2 (de) | 1996-04-30 | 1997-04-30 | Verbesserte erkennung von spezifischen nukleinsäuren |
Country Status (8)
Country | Link |
---|---|
US (2) | US20010007742A1 (de) |
EP (1) | EP0951565B1 (de) |
JP (1) | JP2000508920A (de) |
AT (1) | ATE233826T1 (de) |
CA (1) | CA2252817C (de) |
DE (1) | DE69719557T2 (de) |
SE (1) | SE9601676D0 (de) |
WO (1) | WO1997041254A1 (de) |
Families Citing this family (69)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1994003624A1 (en) * | 1992-08-04 | 1994-02-17 | Auerbach Jeffrey I | Methods for the isothermal amplification of nucleic acid molecules |
US6261808B1 (en) * | 1992-08-04 | 2001-07-17 | Replicon, Inc. | Amplification of nucleic acid molecules via circular replicons |
US20060141475A1 (en) * | 2002-11-19 | 2006-06-29 | Applera Corporation | Polynucleotide sequence detection assays and analysis |
US20050053957A1 (en) * | 2002-11-19 | 2005-03-10 | Applera Corporation | Polynucleotide sequence detection assays |
ATE476523T1 (de) | 2003-06-17 | 2010-08-15 | Human Genetic Signatures Pty | Verfahren zur genomamplifikation |
JP4714148B2 (ja) * | 2003-09-04 | 2011-06-29 | ヒューマン ジェネティック シグネチャーズ ピーティーワイ リミテッド | 核酸検出アッセイ |
US8168777B2 (en) | 2004-04-29 | 2012-05-01 | Human Genetic Signatures Pty. Ltd. | Bisulphite reagent treatment of nucleic acid |
EP1756307A1 (de) * | 2004-05-20 | 2007-02-28 | Trillion Genomics Limited | Verwendung massenmarkierter sonden zum nachweis von zielnukleinsäuren mittels massenspektrometrie |
US7803580B2 (en) | 2004-09-10 | 2010-09-28 | Human Genetic Signatures Pty. Ltd. | Amplification blocker comprising intercalating nucleic acids (INA) containing intercalating pseudonucleotides (IPN) |
ES2399054T3 (es) | 2004-12-03 | 2013-03-25 | Human Genetic Signatures Pty Ltd | Métodos para simplificar ácidos nucleicos microbianos mediante modificación química de citosinas |
EP1883707B1 (de) | 2005-05-26 | 2014-04-09 | Human Genetic Signatures PTY Ltd | Isothermische strangverdrängungsamplifikation unter verwendung von eine nichtreguläre base enthaltenden primern |
CA2621932A1 (en) | 2005-09-14 | 2007-03-22 | Human Genetic Signatures Pty Ltd | Assay for hpv and methylated genomic dna targets to screen for cervical cancer |
EP1879377A3 (de) * | 2006-07-13 | 2010-06-16 | Panasonic Corporation | Tragbare Vorrichtung |
JP5431351B2 (ja) | 2007-11-27 | 2014-03-05 | ヒューマン ジェネティック シグネチャーズ ピーティーワイ リミテッド | バイサルファイト修飾された核酸を増幅およびコピーするための酵素 |
WO2009121021A1 (en) * | 2008-03-28 | 2009-10-01 | Life Technologies Corporation | Degradable arrays for preventing reuse |
SG177252A1 (en) | 2008-12-01 | 2012-03-29 | Lab Corp America Holdings | METHODS AND ASSAYS FOR MEASURING p95 AND/OR p95 IN A SAMPLE AND ANTIBODIES SPECIFIC FOR p95 |
SG172984A1 (en) * | 2009-01-15 | 2011-08-29 | Lab Corp America Holdings | Methods of determining patient response by measurement of her-2 expression |
SG172983A1 (en) | 2009-01-15 | 2011-08-29 | Lab Corp America Holdings | Methods of determining patient response by measurement of her-3 |
CA2760439A1 (en) | 2009-04-30 | 2010-11-04 | Good Start Genetics, Inc. | Methods and compositions for evaluating genetic markers |
JP2013511991A (ja) * | 2009-11-25 | 2013-04-11 | クアンタライフ, インコーポレイテッド | 遺伝子材料を検出する方法および組成物 |
US9163281B2 (en) | 2010-12-23 | 2015-10-20 | Good Start Genetics, Inc. | Methods for maintaining the integrity and identification of a nucleic acid template in a multiplex sequencing reaction |
EP3483285B1 (de) | 2011-02-09 | 2021-07-14 | Bio-Rad Laboratories, Inc. | Analyse von nukleinsäuren |
AU2012219132B2 (en) | 2011-02-15 | 2016-05-12 | Mats Nilsson Bernitz | Method for localized in situ detection of mRNA |
US9556473B2 (en) | 2011-02-15 | 2017-01-31 | Leica Biosystems Newcastle Ltd | Methods for identifying nucleic acid sequences |
US8759036B2 (en) | 2011-03-21 | 2014-06-24 | Affymetrix, Inc. | Methods for synthesizing pools of probes |
US8932819B2 (en) | 2011-07-06 | 2015-01-13 | Affymetrix, Inc. | Assays for affinity profiling of nucleic acid binding proteins |
WO2013033749A1 (en) | 2011-09-07 | 2013-03-14 | Human Genetic Signatures Pty Ltd | Molecular detection assay |
EP2768983A4 (de) | 2011-10-17 | 2015-06-03 | Good Start Genetics Inc | Analyseverfahren |
US8209130B1 (en) | 2012-04-04 | 2012-06-26 | Good Start Genetics, Inc. | Sequence assembly |
US8812422B2 (en) | 2012-04-09 | 2014-08-19 | Good Start Genetics, Inc. | Variant database |
US10227635B2 (en) | 2012-04-16 | 2019-03-12 | Molecular Loop Biosolutions, Llc | Capture reactions |
US10114015B2 (en) | 2013-03-13 | 2018-10-30 | Meso Scale Technologies, Llc. | Assay methods |
CN110308272B (zh) | 2013-03-13 | 2023-09-12 | 中尺度技术有限责任公司 | 改进的测定方法 |
WO2014152421A1 (en) | 2013-03-14 | 2014-09-25 | Good Start Genetics, Inc. | Methods for analyzing nucleic acids |
KR102134168B1 (ko) | 2013-03-15 | 2020-07-15 | 루브리졸 어드밴스드 머티어리얼스, 인코포레이티드 | 중금속이 없는 씨피브이씨 조성물 |
EP3005200A2 (de) | 2013-06-03 | 2016-04-13 | Good Start Genetics, Inc. | Verfahren und systeme zur speicherung von sequenzlesedaten |
CN105555972B (zh) | 2013-07-25 | 2020-07-31 | 伯乐生命医学产品有限公司 | 遗传测定 |
US10851414B2 (en) | 2013-10-18 | 2020-12-01 | Good Start Genetics, Inc. | Methods for determining carrier status |
US11041203B2 (en) | 2013-10-18 | 2021-06-22 | Molecular Loop Biosolutions, Inc. | Methods for assessing a genomic region of a subject |
WO2015175530A1 (en) | 2014-05-12 | 2015-11-19 | Gore Athurva | Methods for detecting aneuploidy |
KR20230022268A (ko) | 2014-05-15 | 2023-02-14 | 메소 스케일 테크놀러지즈, 엘엘시 | 개선된 분석 방법 |
EP3074539B1 (de) | 2014-06-13 | 2018-01-10 | Q-Linea AB | Verfahren für den nachweis und die charakterisierung eines mikroorganismus |
WO2016040446A1 (en) | 2014-09-10 | 2016-03-17 | Good Start Genetics, Inc. | Methods for selectively suppressing non-target sequences |
EP3224595A4 (de) | 2014-09-24 | 2018-06-13 | Good Start Genetics, Inc. | Prozesssteuerung für erhöhte robustheit von genetischen assays |
EP3209798B1 (de) | 2014-10-23 | 2022-07-27 | Ricardo Mancebo | Reagenzien und verfahren für eine isothermische kettenreaktion |
EP4095261A1 (de) | 2015-01-06 | 2022-11-30 | Molecular Loop Biosciences, Inc. | Abtasten auf strukturelle varianten |
GB201507026D0 (en) | 2015-04-24 | 2015-06-10 | Linea Ab Q | Medical sample transportation container |
WO2017020023A2 (en) | 2015-07-29 | 2017-02-02 | Progenity, Inc. | Nucleic acids and methods for detecting chromosomal abnormalities |
US20170298427A1 (en) | 2015-11-16 | 2017-10-19 | Progenity, Inc. | Nucleic acids and methods for detecting methylation status |
GB2554767A (en) | 2016-04-21 | 2018-04-11 | Q Linea Ab | Detecting and characterising a microorganism |
DK3548652T3 (da) | 2016-12-01 | 2024-07-08 | Nautilus Subsidiary Inc | Fremgangsmåder til proteinanalyse |
CA3056650A1 (en) | 2017-03-30 | 2018-10-04 | Pioneer Hi-Bred International, Inc. | Methods of identifying and characterizing gene editing variations in nucleic acids |
WO2019195346A1 (en) | 2018-04-02 | 2019-10-10 | Progenity, Inc. | Methods, systems, and compositions for counting nucleic acid molecules |
EP3931201A1 (de) | 2019-03-01 | 2022-01-05 | Meso Scale Technologies, LLC | Elektrochemilumineszente markierte sonden zur verwendung in immunoassay-verfahren, verfahren mit verwendung davon und kits damit |
WO2020206170A1 (en) | 2019-04-02 | 2020-10-08 | Progenity, Inc. | Methods, systems, and compositions for counting nucleic acid molecules |
AU2021288692A1 (en) | 2020-06-11 | 2023-02-02 | Nautilus Subsidiary, Inc. | Methods and systems for computational decoding of biological, chemical, and physical entities |
EP4214243A1 (de) | 2020-09-21 | 2023-07-26 | Progenity, Inc. | Zusammensetzungen und verfahren zur isolierung von zellfreier dna |
EP4281774A2 (de) | 2021-01-20 | 2023-11-29 | Nautilus Subsidiary, Inc. | Verfahren zur quantifizierung von biomolekülen |
AU2022209365A1 (en) | 2021-01-21 | 2023-07-20 | Nautilus Subsidiary, Inc. | Systems and methods for biomolecule preparation |
CA3209038A1 (en) | 2021-03-11 | 2022-09-15 | Tural AKSEL | Systems and methods for biomolecule retention |
WO2023049073A1 (en) | 2021-09-22 | 2023-03-30 | Nautilus Biotechnology, Inc. | Methods and systems for determining polypeptide interactions |
US20230149883A1 (en) | 2021-11-03 | 2023-05-18 | Nautilus Biotechnology, Inc. | Systems and methods for surface structuring |
US20230314324A1 (en) | 2022-03-29 | 2023-10-05 | Nautilus Subsidiary, Inc. | Integrated arrays for single-analyte processes |
US20230360732A1 (en) | 2022-04-25 | 2023-11-09 | Nautilus Subsidiary, Inc. | Systems and methods for assessing and improving the quality of multiplex molecular assays |
WO2023250364A1 (en) | 2022-06-21 | 2023-12-28 | Nautilus Subsidiary, Inc. | Method for detecting analytes at sites of optically non-resolvable distances |
WO2024059655A1 (en) | 2022-09-15 | 2024-03-21 | Nautilus Subsidiary, Inc. | Characterizing accessibility of macromolecule structures |
WO2024073599A1 (en) | 2022-09-29 | 2024-04-04 | Nautilus Subsidiary, Inc. | Preparation of array surfaces for single-analyte processes |
WO2024124073A1 (en) | 2022-12-09 | 2024-06-13 | Nautilus Subsidiary, Inc. | A method comprising performing on a single-analyte array at least 50 cycles of a process |
US20240201182A1 (en) | 2022-12-15 | 2024-06-20 | Nautilus Subsidiary, Inc. | Inhibition of photon phenomena on single molecule arrays |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5124246A (en) * | 1987-10-15 | 1992-06-23 | Chiron Corporation | Nucleic acid multimers and amplified nucleic acid hybridization assays using same |
US5427930A (en) * | 1990-01-26 | 1995-06-27 | Abbott Laboratories | Amplification of target nucleic acids using gap filling ligase chain reaction |
SE9400522D0 (sv) * | 1994-02-16 | 1994-02-16 | Ulf Landegren | Method and reagent for detecting specific nucleotide sequences |
US5643724A (en) * | 1994-06-06 | 1997-07-01 | Roche Molecular Systems, Inc. | Methods and reagents for Glycophorin A typing |
GB9414934D0 (en) * | 1994-07-25 | 1994-09-14 | Raggio Italgene Spa | Method and reagents for the detection of target nuceic acid sequences |
AU708821B2 (en) | 1995-07-11 | 1999-08-12 | Forfas | Glycosylase mediated detection of nucleotide sequences at candidate loci |
-
1996
- 1996-04-30 SE SE9601676A patent/SE9601676D0/xx unknown
-
1997
- 1997-04-30 CA CA002252817A patent/CA2252817C/en not_active Expired - Lifetime
- 1997-04-30 JP JP9538820A patent/JP2000508920A/ja not_active Ceased
- 1997-04-30 EP EP97921072A patent/EP0951565B1/de not_active Expired - Lifetime
- 1997-04-30 US US09/171,935 patent/US20010007742A1/en not_active Abandoned
- 1997-04-30 AT AT97921072T patent/ATE233826T1/de not_active IP Right Cessation
- 1997-04-30 DE DE69719557T patent/DE69719557T2/de not_active Expired - Lifetime
- 1997-04-30 WO PCT/SE1997/000737 patent/WO1997041254A1/en active IP Right Grant
-
2001
- 2001-12-31 US US10/029,913 patent/US7351528B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
US20020102592A1 (en) | 2002-08-01 |
JP2000508920A (ja) | 2000-07-18 |
US7351528B2 (en) | 2008-04-01 |
CA2252817C (en) | 2009-07-07 |
CA2252817A1 (en) | 1997-11-06 |
DE69719557T2 (de) | 2004-02-26 |
EP0951565B1 (de) | 2003-03-05 |
US20010007742A1 (en) | 2001-07-12 |
ATE233826T1 (de) | 2003-03-15 |
SE9601676D0 (sv) | 1996-04-30 |
WO1997041254A1 (en) | 1997-11-06 |
EP0951565A1 (de) | 1999-10-27 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DE69719557D1 (de) | Verbesserte erkennung von spezifischen nukleinsäuren | |
DK56091D0 (da) | Nucleinsyreprober indeholdende en forbedret molekylaer omskifter samt analyser og kits, hvori disse indgaar | |
ES2109226T3 (es) | Deteccion de secuencias de acidos nucleicos usando polarizacion de fluorescencia. | |
SE0000538D0 (sv) | Methods and kits for proximity probing | |
YU49789A (sh) | Postopek za detekcijo nukleotidnih sekvenc | |
ATE141956T1 (de) | Verfahren zur vervielfältigung von nukleinsäuresequenzen | |
DE69506393D1 (de) | Hybridisation-ligitation-verfahren zum nachweis von spezifischen dns sequenzen | |
DE69637726D1 (de) | Gruppen zum einfangen von nukleinsäuren | |
ES2177590T3 (es) | Deteccion de amplificacion de acidos nucleicos. | |
ATE515693T1 (de) | Nachweis einer zielsubstanz in einer probe | |
DK0407789T3 (da) | Fremgangsmåde til detektering af nukleinsyrer | |
DE59107797D1 (de) | Verfahren zum Nachweis von phosphoryliertes Tyrosin enthaltenden Proteinen | |
KR930002371A (ko) | 핵산의 고정화 방법 | |
DE69630517D1 (de) | Sonde zur anwendung in der analyse von nukleinsaüren und verfahren der detektion basierend auf excimer-fluoreszenz | |
DE69941690D1 (de) | Methoden, testsätze und kompositionen zur detektion und quantifizierung von zielsequenzen | |
BR9609390A (pt) | Ensaio quimiluminescente de ligação específica com não-separação | |
DE69632826D1 (de) | Nukleinsaeure erkennung von hepatitis gb virus | |
EP1008658A4 (de) | Festphase zur erkennung von nukleinsäuren und verfahren zu deren erkennung | |
ATE383441T1 (de) | Verfahren zur detektion von nukleinsäure- zielmolekülen bei dem enzym verbundenen sonde einfangtest sowie geeignetes testsystem | |
ATE158815T1 (de) | Hippurikasegen | |
WO2000075362A3 (en) | Method for identifying novel transcriptional regulatory proteins |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
8327 | Change in the person/name/address of the patent owner |
Owner name: LANDEGREN GENE TECHNOLOGY AB, UPPSALA, SE |
|
8381 | Inventor (new situation) |
Inventor name: LANDEGREN, ULF, 756 45 UPPSALA, SE |
|
8364 | No opposition during term of opposition |