DE60321961D1 - Verfahren zum genmutationsnachweis - Google Patents

Verfahren zum genmutationsnachweis

Info

Publication number
DE60321961D1
DE60321961D1 DE60321961T DE60321961T DE60321961D1 DE 60321961 D1 DE60321961 D1 DE 60321961D1 DE 60321961 T DE60321961 T DE 60321961T DE 60321961 T DE60321961 T DE 60321961T DE 60321961 D1 DE60321961 D1 DE 60321961D1
Authority
DE
Germany
Prior art keywords
dna amplification
labeled
hybridization
labeling agent
detection procedure
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60321961T
Other languages
English (en)
Inventor
Yoichi Matsubara
Shigeo Kure
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kure Shigeo Sendai Miyagi Jp
Matsubara Yoichi Sendai Miyagi Jp
Sekisui Medical Co Ltd
Original Assignee
Daiichi Pure Chemicals Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Daiichi Pure Chemicals Co Ltd filed Critical Daiichi Pure Chemicals Co Ltd
Application granted granted Critical
Publication of DE60321961D1 publication Critical patent/DE60321961D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5308—Immunoassay; Biospecific binding assay; Materials therefor for analytes not provided for elsewhere, e.g. nucleic acids, uric acid, worms, mites
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Iron Core Of Rotating Electric Machines (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Saccharide Compounds (AREA)
DE60321961T 2002-11-07 2003-11-07 Verfahren zum genmutationsnachweis Expired - Lifetime DE60321961D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2002323419 2002-11-07
PCT/JP2003/014204 WO2004042057A1 (ja) 2002-11-07 2003-11-07 遺伝子変異検出法

Publications (1)

Publication Number Publication Date
DE60321961D1 true DE60321961D1 (de) 2008-08-14

Family

ID=32310418

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60321961T Expired - Lifetime DE60321961D1 (de) 2002-11-07 2003-11-07 Verfahren zum genmutationsnachweis

Country Status (11)

Country Link
US (2) US20060127907A1 (de)
EP (1) EP1580269B1 (de)
JP (1) JP4425142B2 (de)
KR (1) KR101078977B1 (de)
CN (1) CN100343389C (de)
AT (1) ATE399882T1 (de)
AU (1) AU2003277612A1 (de)
CA (1) CA2506654C (de)
DE (1) DE60321961D1 (de)
NO (1) NO338640B1 (de)
WO (1) WO2004042057A1 (de)

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JPWO2009034842A1 (ja) * 2007-09-11 2010-12-24 株式会社カネカ 核酸検出方法、および核酸検出キット
AU2009253675A1 (en) 2008-05-28 2009-12-03 Genomedx Biosciences, Inc. Systems and methods for expression-based discrimination of distinct clinical disease states in prostate cancer
US10407731B2 (en) 2008-05-30 2019-09-10 Mayo Foundation For Medical Education And Research Biomarker panels for predicting prostate cancer outcomes
DE102008028908B3 (de) * 2008-06-18 2009-12-31 IfP Privates Institut für Produktqualität GmbH Nachweis eines Analyten in einem wässrigen Medium
JP5854838B2 (ja) 2008-11-07 2016-02-09 ユニバーシティ・オブ・ユタ・リサーチ・ファウンデイション 対立遺伝子増幅バイアス
US9495515B1 (en) 2009-12-09 2016-11-15 Veracyte, Inc. Algorithms for disease diagnostics
US10236078B2 (en) 2008-11-17 2019-03-19 Veracyte, Inc. Methods for processing or analyzing a sample of thyroid tissue
JP6257125B2 (ja) 2008-11-17 2018-01-10 ベラサイト インコーポレイテッド 疾患診断のための分子プロファイリングの方法および組成物
US9074258B2 (en) 2009-03-04 2015-07-07 Genomedx Biosciences Inc. Compositions and methods for classifying thyroid nodule disease
US8669057B2 (en) 2009-05-07 2014-03-11 Veracyte, Inc. Methods and compositions for diagnosis of thyroid conditions
JP5597939B2 (ja) * 2009-06-01 2014-10-01 凸版印刷株式会社 部分競合型プローブを用いた標的塩基配列の検出方法
JP2011062088A (ja) * 2009-09-15 2011-03-31 Ihi Corp レジオネラ菌検出方法
US10446272B2 (en) 2009-12-09 2019-10-15 Veracyte, Inc. Methods and compositions for classification of samples
CN106498076A (zh) 2010-05-11 2017-03-15 威拉赛特公司 用于诊断病状的方法和组合物
AU2012352153B2 (en) 2011-12-13 2018-07-26 Veracyte, Inc. Cancer diagnostics using non-coding transcripts
WO2014028884A2 (en) 2012-08-16 2014-02-20 Genomedx Biosciences, Inc. Cancer diagnostics using biomarkers
US20140244556A1 (en) * 2013-02-27 2014-08-28 Abdul Saleh Methods for and apparatus generating automated pharmaco genetics correlation
US11976329B2 (en) 2013-03-15 2024-05-07 Veracyte, Inc. Methods and systems for detecting usual interstitial pneumonia
BR112015022490A2 (pt) 2013-03-15 2017-07-18 Veracyte Inc métodos e composições para classificação de amostras
CN114606309A (zh) 2014-11-05 2022-06-10 威拉赛特公司 使用机器学习和高维转录数据的诊断系统和方法
CN104531883B (zh) * 2015-01-14 2018-02-02 北京圣谷同创科技发展有限公司 Pkd1基因突变的检测试剂盒及检测方法
JP6757942B2 (ja) * 2016-08-03 2020-09-23 東洋鋼鈑株式会社 ハイブリダイゼーション用バッファー組成物及びハイブリダイゼーション方法
EP3504348B1 (de) 2016-08-24 2022-12-14 Decipher Biosciences, Inc. Verwendung von genomischen signaturen zur vorhersage des ansprechens von patienten mit prostatakrebs auf postoperative strahlentherapie
AU2018210695A1 (en) 2017-01-20 2019-08-08 The University Of British Columbia Molecular subtyping, prognosis, and treatment of bladder cancer
EP3593140A4 (de) 2017-03-09 2021-01-06 Decipher Biosciences, Inc. Subtypisierung von prostatakrebs zur vorhersage der reaktion auf eine hormontherapie
EP3622087A4 (de) 2017-05-12 2021-06-16 Decipher Biosciences, Inc. Genetische signaturen zur vorhersage der prostatakrebsmetastasierung und identifizierung von tumoraggressivität
US11217329B1 (en) 2017-06-23 2022-01-04 Veracyte, Inc. Methods and systems for determining biological sample integrity
JP2019012035A (ja) * 2017-06-30 2019-01-24 キヤノン株式会社 薄層クロマトグラフィー用のキット、薄層クロマトグラフィー用の展開液、及び薄層クロマトグラフィー
CN108315408A (zh) * 2018-04-26 2018-07-24 宁波美丽人生医学检验所有限公司 用于检测硝酸甘油药物相关基因的引物组合物及试剂盒

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US5753433A (en) * 1909-12-05 1998-05-19 Boehringer Mannheim Gmbh Method for the sensitive detection of nucleic acids
US6040166A (en) * 1985-03-28 2000-03-21 Roche Molecular Systems, Inc. Kits for amplifying and detecting nucleic acid sequences, including a probe
CA1284931C (en) 1986-03-13 1991-06-18 Henry A. Erlich Process for detecting specific nucleotide variations and genetic polymorphisms present in nucleic acids
US5635347A (en) * 1986-04-30 1997-06-03 Igen, Inc. Rapid assays for amplification products
IE61148B1 (en) * 1988-03-10 1994-10-05 Ici Plc Method of detecting nucleotide sequences
CA1341584C (en) * 1988-04-06 2008-11-18 Bruce Wallace Method of amplifying and detecting nucleic acid sequences
KR920700360A (ko) * 1989-03-22 1992-02-19 하리크 프리드리히 미끄럼 베어링
JP2715651B2 (ja) * 1990-10-08 1998-02-18 東洋紡績株式会社 毒素原性大腸菌検出用オリゴヌクレオチド、毒素原性大腸菌の検出法及び検出用キット
NZ240079A (en) * 1990-10-09 1993-07-27 Boehringer Mannheim Gmbh Method for the detection of a nucleic acid or part thereof
DE4129653A1 (de) * 1991-09-06 1993-03-11 Boehringer Mannheim Gmbh Verfahren zum nachweis aehnlicher nukleinsaeuren
US5650277A (en) * 1992-07-02 1997-07-22 Diagenetics Ltd. Method of determining the presence and quantifying the number of di- and trinucleotide repeats
DE69332666T2 (de) * 1992-07-02 2003-12-18 Pronto Diagnostics Ltd Verfahren zur einfachen nukleotid-primer-verlängerung zum nachweis spezifischer allele und dafür geeigneter kit
JPH0779779A (ja) * 1993-09-13 1995-03-28 Toyobo Co Ltd 毒素原性大腸菌検出用オリゴヌクレオチドおよびその用途
WO1995025538A1 (en) * 1994-03-18 1995-09-28 The General Hospital Corporation Cleaved amplified rflp detection methods
EP0777749B1 (de) * 1994-08-19 2002-10-30 PE Corporation (NY) Gekoppeltes ampflikation- und ligationverfahren
US6090620A (en) * 1995-12-29 2000-07-18 University Of Washington Genes and gene products related to Werner's syndrome
US6613508B1 (en) * 1996-01-23 2003-09-02 Qiagen Genomics, Inc. Methods and compositions for analyzing nucleic acid molecules utilizing sizing techniques
EP0817866A1 (de) * 1996-01-26 1998-01-14 Innogenetics N.V. Verfahren für den nachweis von drogen-induzierten mutationen in dem reverse transcriptase gen
US6013440A (en) * 1996-03-11 2000-01-11 Affymetrix, Inc. Nucleic acid affinity columns
DE19730359A1 (de) * 1997-07-15 1999-01-21 Boehringer Mannheim Gmbh Integriertes Verfahren und System zur Amplifizierung und zum Nachweis von Nukleinsäuren
DE19732086C2 (de) * 1997-07-25 2002-11-21 Univ Leipzig Verfahren zur quantitativen Bestimmung von Eubakterien
US5969123A (en) * 1998-03-06 1999-10-19 Millennium Biotherapeutics, Inc. Nucleic acid molecules derived from a brain tissue library
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US7582420B2 (en) * 2001-07-12 2009-09-01 Illumina, Inc. Multiplex nucleic acid reactions
WO2003066897A2 (en) * 2002-02-08 2003-08-14 Evotec Technologies Gmbh Specific multiplex analysis of nucleic acids

Also Published As

Publication number Publication date
EP1580269A1 (de) 2005-09-28
EP1580269B1 (de) 2008-07-02
CA2506654C (en) 2014-02-25
CA2506654A1 (en) 2004-05-21
NO20052692D0 (no) 2005-06-06
US20060127907A1 (en) 2006-06-15
CN100343389C (zh) 2007-10-17
AU2003277612A1 (en) 2004-06-07
US20080318238A1 (en) 2008-12-25
US9677127B2 (en) 2017-06-13
KR101078977B1 (ko) 2011-11-01
EP1580269A4 (de) 2006-01-11
WO2004042057A1 (ja) 2004-05-21
CN1729289A (zh) 2006-02-01
ATE399882T1 (de) 2008-07-15
NO338640B1 (no) 2016-09-26
KR20050086431A (ko) 2005-08-30
JP4425142B2 (ja) 2010-03-03
NO20052692L (no) 2005-06-06
JPWO2004042057A1 (ja) 2006-03-09

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Legal Events

Date Code Title Description
8327 Change in the person/name/address of the patent owner

Owner name: KURE, SHIGEO, SENDAI, MIYAGI, JP

Owner name: MATSUBARA, YOICHI, SENDAI, MIYAGI, JP

Owner name: SEKISUI MEDICAL CO., LTD., TOKYO, JP

8364 No opposition during term of opposition