ATE534748T1 - Direkter snp-nachweis mit nichtamplifizierter dna - Google Patents

Direkter snp-nachweis mit nichtamplifizierter dna

Info

Publication number
ATE534748T1
ATE534748T1 AT03810070T AT03810070T ATE534748T1 AT E534748 T1 ATE534748 T1 AT E534748T1 AT 03810070 T AT03810070 T AT 03810070T AT 03810070 T AT03810070 T AT 03810070T AT E534748 T1 ATE534748 T1 AT E534748T1
Authority
AT
Austria
Prior art keywords
nucleic acid
amplified dna
acid molecules
snp detection
direct snp
Prior art date
Application number
AT03810070T
Other languages
English (en)
Inventor
Yijia Bao
Sudhakar Marla
Uwe Muller
James Storhoff
Susan Hetzel
Original Assignee
Nanosphere Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nanosphere Inc filed Critical Nanosphere Inc
Application granted granted Critical
Publication of ATE534748T1 publication Critical patent/ATE534748T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C12Q1/689—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y10/00—Nanotechnology for information processing, storage or transmission, e.g. quantum computing or single electron logic
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
    • C12Q1/6837—Enzymatic or biochemical coupling of nucleic acids to a solid phase using probe arrays or probe chips
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Analytical Chemistry (AREA)
  • Nanotechnology (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Microbiology (AREA)
  • Mathematical Physics (AREA)
  • Theoretical Computer Science (AREA)
  • Medical Informatics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
AT03810070T 2002-12-12 2003-12-12 Direkter snp-nachweis mit nichtamplifizierter dna ATE534748T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US43344202P 2002-12-12 2002-12-12
US43277202P 2002-12-12 2002-12-12
PCT/US2003/039836 WO2004053105A2 (en) 2002-12-12 2003-12-12 Direct snp detection with unamplified dna

Publications (1)

Publication Number Publication Date
ATE534748T1 true ATE534748T1 (de) 2011-12-15

Family

ID=32511667

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03810070T ATE534748T1 (de) 2002-12-12 2003-12-12 Direkter snp-nachweis mit nichtamplifizierter dna

Country Status (7)

Country Link
US (1) US20050059030A1 (de)
EP (1) EP1578952B1 (de)
JP (1) JP2006517786A (de)
AT (1) ATE534748T1 (de)
AU (1) AU2003302253B2 (de)
CA (1) CA2508359A1 (de)
WO (1) WO2004053105A2 (de)

Families Citing this family (62)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6750016B2 (en) 1996-07-29 2004-06-15 Nanosphere, Inc. Nanoparticles having oligonucleotides attached thereto and uses therefor
US6582921B2 (en) 1996-07-29 2003-06-24 Nanosphere, Inc. Nanoparticles having oligonucleotides attached thereto and uses thereof
US6506564B1 (en) 1996-07-29 2003-01-14 Nanosphere, Inc. Nanoparticles having oligonucleotides attached thereto and uses therefor
US7169556B2 (en) 1996-07-29 2007-01-30 Nanosphere, Inc. Nanoparticles having oligonucleotides attached thereto and uses therefor
US7098320B1 (en) 1996-07-29 2006-08-29 Nanosphere, Inc. Nanoparticles having oligonucleotides attached thereto and uses therefor
US6974669B2 (en) 2000-03-28 2005-12-13 Nanosphere, Inc. Bio-barcodes based on oligonucleotide-modified nanoparticles
AU768535B2 (en) 1998-11-30 2003-12-18 Nanosphere, Inc. Nanoparticles with polymer shells
CA2396113C (en) 2000-01-13 2009-04-07 Nanosphere, Inc. Nanoparticles having oligonucleotides attached thereto and uses therefor
AU2002239726A1 (en) 2001-05-25 2002-12-09 Northwestern University Non-alloying core shell nanoparticles
US7147687B2 (en) 2001-05-25 2006-12-12 Nanosphere, Inc. Non-alloying core shell nanoparticles
CA2466656C (en) 2001-11-09 2013-07-02 Nanosphere, Inc. Bioconjugate-nanoparticle probes
US20030211488A1 (en) 2002-05-07 2003-11-13 Northwestern University Nanoparticle probs with Raman spectrocopic fingerprints for analyte detection
JP2005532456A (ja) 2002-07-02 2005-10-27 ナノスフェアー インコーポレイテッド ナノ粒子ポリアニオン複合物ならびに分析物の検出における同複合物の用途
US20060183132A1 (en) * 2005-02-14 2006-08-17 Perlegen Sciences, Inc. Selection probe amplification
WO2005001113A2 (en) * 2003-06-27 2005-01-06 Thomas Jefferson University Methods for detecting nucleic acid variations
WO2005054516A2 (en) * 2003-11-26 2005-06-16 Advandx, Inc. Peptide nucleic acid probes for analysis of certain staphylococcus species
CA2834041C (en) * 2003-12-31 2017-05-16 President And Fellows Of Harvard College Assay device and method
JP2005227154A (ja) * 2004-02-13 2005-08-25 Eiichi Tamiya 特定遺伝子検出方法及びこれに用いる塩基修飾ナノ粒子、1塩基変異型遺伝子識別用試薬
JP2008507296A (ja) * 2004-07-26 2008-03-13 ナノスフェアー インコーポレイテッド 混合培養物中でメチシリン耐性黄色ブドウ球菌とメチシリン感受性黄色ブドウ球菌とを区別する方法
JP4742544B2 (ja) * 2004-09-08 2011-08-10 凸版印刷株式会社 遺伝子チェック装置及び方法
WO2007044025A2 (en) * 2004-11-22 2007-04-19 Nanosphere, Inc. Method for detecting analytes based on evanescent illumination and scatter-based detection of nonoparticle probe complexes
US7611908B2 (en) 2005-05-02 2009-11-03 Bioscale, Inc. Method and apparatus for therapeutic drug monitoring using an acoustic device
US7749445B2 (en) 2005-05-02 2010-07-06 Bioscale, Inc. Method and apparatus for analyzing bioprocess fluids
US7300631B2 (en) 2005-05-02 2007-11-27 Bioscale, Inc. Method and apparatus for detection of analyte using a flexural plate wave device and magnetic particles
WO2006123943A1 (en) 2005-05-20 2006-11-23 Synergenz Bioscience Limited Methods of analysis of polymorphisms and uses thereof
WO2007002567A2 (en) * 2005-06-23 2007-01-04 Nanosphere, Inc. Selective isolation and concentration of nucleic acids from complex samples
US20070003938A1 (en) * 2005-06-30 2007-01-04 Perlegen Sciences, Inc. Hybridization of genomic nucleic acid without complexity reduction
JP4822753B2 (ja) * 2005-07-11 2011-11-24 一般社団法人オンチップ・セロミクス・コンソーシアム 細胞構成物質分取チップならびに細胞構成物質解析システム及びこれらを用いる細胞構成物質解析法
EP1915466B1 (de) * 2005-08-19 2010-11-24 Nanosphere, Inc. Verfahren zur herstellung von hybridsubstraten mit dna und antikörpern sowie verwendungen davon
US20070174128A1 (en) * 2005-11-30 2007-07-26 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Computational and/or control systems related to individualized pharmaceutical and nutraceutical selection and packaging
JP2009520209A (ja) * 2005-12-19 2009-05-21 バイオスケール, インコーポレイテッド バイオプロセス液を分析するための方法および装置
EP2284539B1 (de) * 2005-12-19 2014-04-09 Bioscale, Inc. Verfahren und Gerät zur Untersuchung von Bioprozess-Flüssigkeiten
BRPI0707348A2 (pt) * 2006-01-19 2011-05-03 Univ New York State Res Found métodos e dispositivos para detecção e identificação de moléculas biológicas e microesferas codificadas
WO2007139402A2 (en) * 2006-05-30 2007-12-06 Synergenz Bioscience Limited Methods and compositions for assessment of pulmonary function and disorders
WO2008020090A1 (es) * 2006-08-18 2008-02-21 Laboratorios Indas, S.A. Método y kit para diagnosticar el riesgo de desarrollar una enfermedad trombótica venosa
WO2008048120A2 (en) * 2006-10-17 2008-04-24 Synergenz Bioscience Limited Methods and compositions for assessment of pulmonary function and disorders
CA2580589C (en) * 2006-12-19 2016-08-09 Fio Corporation Microfluidic detection system
AU2007334740A1 (en) * 2006-12-19 2008-06-26 Synergenz Bioscience Limited Methods and compositions for the assessment of cardiovascular function and disorders
US8360321B2 (en) 2007-04-02 2013-01-29 Fio Corporation System and method of deconvolving multiplexed fluorescence spectral signals generated by quantum dot optical coding technology
US8597729B2 (en) 2007-06-22 2013-12-03 Fio Corporation Systems and methods for manufacturing quantum dot-doped polymer microbeads
CN101809433A (zh) * 2007-07-09 2010-08-18 Fio公司 用于增强试样中靶分子荧光检测的系统和方法
CN101809577B (zh) * 2007-07-23 2013-04-17 Fio公司 用于整理、存储、分析和支持访问与生物和环境检查对象有关的所收集和分析的数据的方法和系统
WO2009033056A1 (en) 2007-09-06 2009-03-12 Bioscale, Inc. Reusable detection surfaces and methods of using same
CN101861203B (zh) 2007-10-12 2014-01-22 Fio公司 用于形成浓缩体积的微珠的流动聚焦方法和系统以及形成的微珠
US20110045481A1 (en) 2008-01-25 2011-02-24 Patrick Gladding Methods and compositions for the assessment of drug response
US9792809B2 (en) 2008-06-25 2017-10-17 Fio Corporation Bio-threat alert system
RU2515209C2 (ru) 2008-08-29 2014-05-10 Эф-Ай-Оу Корпорейшн Одноразовый портативный диагностический прибор и соответствующая система и способ исследования биологических и природных образцов
CN104374932A (zh) 2009-01-13 2015-02-25 Fio公司 与电子设备和快速诊断测试中的测试盒结合使用的手持诊断测试设备
GB0904934D0 (en) 2009-03-23 2009-05-06 Geneseqe As Method and apparatus for detecting molecules
US9572880B2 (en) 2010-08-27 2017-02-21 Sienna Biopharmaceuticals, Inc. Ultrasound delivery of nanoparticles
JP5945540B2 (ja) 2010-08-27 2016-07-05 シエナ バイオファーマシューティカルズ,インク. 標的とされた熱変調のための組成物及び方法
GB201016484D0 (en) 2010-09-30 2010-11-17 Geneseque As Method
CN104204228A (zh) 2012-02-14 2014-12-10 康奈尔大学 使用组合的核酸酶、连接和聚合酶反应用于核酸序列的相对定量、表达或拷贝变化的方法
DK2906286T3 (en) 2012-10-11 2017-07-17 Nanocomposix Inc SILVER CHARACTER COMPOSITIONS AND PROCEDURES
US20180258473A1 (en) * 2015-11-10 2018-09-13 Administracion General De La Comunidad Autonoma De Euskadi Diagnostic methods and devices
US20180057881A1 (en) * 2016-08-24 2018-03-01 William Beaumont Hospital Methods of detecting snps related to mrsa and ssi
US11331019B2 (en) 2017-08-07 2022-05-17 The Research Foundation For The State University Of New York Nanoparticle sensor having a nanofibrous membrane scaffold
JP2021534804A (ja) 2018-09-03 2021-12-16 ビスビュー メディカル,インコーポレイテッド 抗生物質感受性検査のための装置および方法
EP4085149A4 (de) 2020-01-03 2024-03-06 Visby Medical, Inc. Vorrichtungen und verfahren zur prüfung von antibiotischer suszeptibilität
CN111733215A (zh) * 2020-06-24 2020-10-02 深圳市光与生物科技有限公司 一种基于上转换荧光探针的核酸快速检测方法
EP4495257A1 (de) * 2022-04-21 2025-01-22 Ezdiatech Inc. Mikropartikelsonde zur analyse von einzelnukleotidpolymorphismus
CN118658530B (zh) * 2024-06-19 2024-12-17 中国科学院水生生物研究所 生成淡水经济鱼snp探针的方法、装置、电子设备及介质

Family Cites Families (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5200313A (en) * 1983-08-05 1993-04-06 Miles Inc. Nucleic acid hybridization assay employing detectable anti-hybrid antibodies
US5288609A (en) * 1984-04-27 1994-02-22 Enzo Diagnostics, Inc. Capture sandwich hybridization method and composition
US5137827A (en) * 1986-03-25 1992-08-11 Midwest Research Technologies, Inc. Diagnostic element for electrical detection of a binding reaction
US5360895A (en) * 1987-04-22 1994-11-01 Associated Universities, Inc. Derivatized gold clusters and antibody-gold cluster conjugates
US5151510A (en) * 1990-04-20 1992-09-29 Applied Biosystems, Inc. Method of synethesizing sulfurized oligonucleotide analogs
US5474796A (en) * 1991-09-04 1995-12-12 Protogene Laboratories, Inc. Method and apparatus for conducting an array of chemical reactions on a support surface
US5849486A (en) * 1993-11-01 1998-12-15 Nanogen, Inc. Methods for hybridization analysis utilizing electrically controlled hybridization
EP0613585A4 (de) * 1991-11-22 1995-06-21 Univ California Halbleitende nanokristalle, die durch selbstzusammengesetzte einzelschichten mit festen anorganischen oberflüchen verbunden sind.
US5472881A (en) * 1992-11-12 1995-12-05 University Of Utah Research Foundation Thiol labeling of DNA for attachment to gold surfaces
US5637508A (en) * 1993-03-26 1997-06-10 Geo-Centers, Inc. Biomolecules bound to polymer or copolymer coated catalytic inorganic particles, immunoassays using the same and kits containing the same
US5384265A (en) * 1993-03-26 1995-01-24 Geo-Centers, Inc. Biomolecules bound to catalytic inorganic particles, immunoassays using the same
WO1995021271A1 (en) * 1994-02-07 1995-08-10 Molecular Tool, Inc. Ligase/polymerase-mediated genetic bit analysistm of single nucleotide polymorphisms and its use in genetic analysis
US5599668A (en) * 1994-09-22 1997-02-04 Abbott Laboratories Light scattering optical waveguide method for detecting specific binding events
AU730633B2 (en) * 1996-05-29 2001-03-08 Phillip Belgrader Detection of nucleic acid sequence differences using coupled ligase detection and polymerase chain reactions
US6506564B1 (en) * 1996-07-29 2003-01-14 Nanosphere, Inc. Nanoparticles having oligonucleotides attached thereto and uses therefor
US6361944B1 (en) * 1996-07-29 2002-03-26 Nanosphere, Inc. Nanoparticles having oligonucleotides attached thereto and uses therefor
US5830986A (en) * 1996-10-28 1998-11-03 Massachusetts Institute Of Technology Methods for the synthesis of functionalizable poly(ethylene oxide) star macromolecules
US5858671A (en) * 1996-11-01 1999-01-12 The University Of Iowa Research Foundation Iterative and regenerative DNA sequencing method
US5900481A (en) * 1996-11-06 1999-05-04 Sequenom, Inc. Bead linkers for immobilizing nucleic acids to solid supports
US5939021A (en) * 1997-01-23 1999-08-17 Hansen; W. Peter Homogeneous binding assay
IL156002A0 (en) * 1997-02-12 2003-12-23 Eugene Y Chan Methods and products for analyzing polymers
US5990479A (en) * 1997-11-25 1999-11-23 Regents Of The University Of California Organo Luminescent semiconductor nanocrystal probes for biological applications and process for making and using such probes
US6406921B1 (en) * 1998-07-14 2002-06-18 Zyomyx, Incorporated Protein arrays for high-throughput screening
US6251303B1 (en) * 1998-09-18 2001-06-26 Massachusetts Institute Of Technology Water-soluble fluorescent nanocrystals
US6306610B1 (en) * 1998-09-18 2001-10-23 Massachusetts Institute Of Technology Biological applications of quantum dots
US6203989B1 (en) * 1998-09-30 2001-03-20 Affymetrix, Inc. Methods and compositions for amplifying detectable signals in specific binding assays
US6277489B1 (en) * 1998-12-04 2001-08-21 The Regents Of The University Of California Support for high performance affinity chromatography and other uses
US6410231B1 (en) * 1999-02-26 2002-06-25 Incyte Genomics, Inc. SNP detection
CA2937907C (en) * 1999-09-28 2017-08-22 Geneohm Sciences Canada Inc. Nucleic acids, methods and kits for the detection of campylobacter
US20020090649A1 (en) * 1999-12-15 2002-07-11 Tony Chan High density column and row addressable electrode arrays
US7163790B2 (en) * 2001-11-28 2007-01-16 Bio-Rad Laboratories, Inc. Parallel polymorphism scoring by amplification and error correction
US20030211488A1 (en) * 2002-05-07 2003-11-13 Northwestern University Nanoparticle probs with Raman spectrocopic fingerprints for analyte detection
WO2004031408A1 (en) * 2002-09-30 2004-04-15 F.Hoffmann-La Roche Ag Oligonucleotides for genotyping thymidylate synthase gene
US7354706B2 (en) * 2003-09-09 2008-04-08 The Regents Of The University Of Colorado, A Body Corporate Use of photopolymerization for amplification and detection of a molecular recognition event
WO2005047521A2 (en) * 2003-11-10 2005-05-26 Investigen, Inc. Methods of preparing nucleic acid for detection

Also Published As

Publication number Publication date
WO2004053105A3 (en) 2006-04-06
JP2006517786A (ja) 2006-08-03
AU2003302253A1 (en) 2004-06-30
WO2004053105A9 (en) 2004-10-07
WO2004053105A2 (en) 2004-06-24
CA2508359A1 (en) 2004-06-24
US20050059030A1 (en) 2005-03-17
AU2003302253B2 (en) 2007-06-28
EP1578952A4 (de) 2008-05-07
EP1578952A2 (de) 2005-09-28
EP1578952B1 (de) 2011-11-23

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