ES2006377A6 - Un metodo de analisis de acidos nucleicos por hibridacion. - Google Patents

Un metodo de analisis de acidos nucleicos por hibridacion.

Info

Publication number
ES2006377A6
ES2006377A6 ES8800740A ES8800740A ES2006377A6 ES 2006377 A6 ES2006377 A6 ES 2006377A6 ES 8800740 A ES8800740 A ES 8800740A ES 8800740 A ES8800740 A ES 8800740A ES 2006377 A6 ES2006377 A6 ES 2006377A6
Authority
ES
Spain
Prior art keywords
nucleic acid
assays
reagent combination
kit therefor
nucleic acids
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES8800740A
Other languages
English (en)
Inventor
Hans Erik Soderlung
Weckman Arja Marjatta
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sangtec Medical AB
Original Assignee
Orion Yhtyma Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Orion Yhtyma Oy filed Critical Orion Yhtyma Oy
Publication of ES2006377A6 publication Critical patent/ES2006377A6/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701—Specific hybridization probes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/686—Polymerase chain reaction [PCR]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

UN METODO DE ANALISIS DE ACIDOS NUCLEICOS POR HIBRIDACION, EN DONDE LAS SONDAS DETECTORAS O CAPTURADORAS SON CEBADORES MODIFICADOS QUE SE INCORPORAN EN COPIAS DEL ACIDO NUCLEICO OBJETIVO ANTES DE LA REACCION DE HIBRIDACION. EL METODO COMPRENDE LA ADICION DE AL MENOS DOS CEBADORES MODIFICADOS, CUYOS CEBADORES SON DETECTORES O CAPTURADORES, A UNA SOLUCION DE MUESTRA DESNATURALIZADA. LOS CEBADORES MODIFICADOS SE TEMPLARAN CADA UNO DE ELLOS A SU HEBRA COMPLEMENTARIA DEL ACIDO NUCLEICO OBJETIVO, ES DECIR, EL MOLDE, Y TRAS LA ADICION DE UN ENZIMA DE SINTESIS DE ACIDO NUCLEICO DEPENDIENTE DEL MOLDE, SE ALARGARAN LOS CEBADORES. EL PROCESO SE REALIZA EFICAZMENTE IN VITRO CREANDO NUEVAS HEBRAS DE ACIDOS NUCLEICOS QUE PUEDEN SER UNA LONGITUD DE VARIOS MILES DE BASES, SIEMPRE QUE LAS CONDICIONES SEAN ADECUADAS.
ES8800740A 1987-03-11 1988-03-11 Un metodo de analisis de acidos nucleicos por hibridacion. Expired ES2006377A6 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US2460487A 1987-03-11 1987-03-11

Publications (1)

Publication Number Publication Date
ES2006377A6 true ES2006377A6 (es) 1989-04-16

Family

ID=21821443

Family Applications (1)

Application Number Title Priority Date Filing Date
ES8800740A Expired ES2006377A6 (es) 1987-03-11 1988-03-11 Un metodo de analisis de acidos nucleicos por hibridacion.

Country Status (25)

Country Link
US (2) US5476769A (es)
JP (1) JP3244500B2 (es)
AT (1) AT395434B (es)
AU (1) AU622104B2 (es)
BE (1) BE1003990A5 (es)
CA (1) CA1338207C (es)
CH (1) CH677285A5 (es)
DD (1) DD272664A5 (es)
DE (1) DE3807994C2 (es)
DK (1) DK175384B1 (es)
ES (1) ES2006377A6 (es)
FI (1) FI94429C (es)
FR (1) FR2613077A1 (es)
GB (1) GB2202328B (es)
GR (1) GR1000315B (es)
HU (1) HU202583B (es)
IE (1) IE61664B1 (es)
IL (3) IL85480A0 (es)
IT (1) IT1216048B (es)
LU (1) LU87153A1 (es)
NL (1) NL194922C (es)
NO (1) NO172909C (es)
NZ (1) NZ223700A (es)
PT (1) PT86937B (es)
SE (1) SE500262C2 (es)

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DD272664A5 (de) 1989-10-18
HUT50868A (en) 1990-03-28
FI94429C (fi) 1995-09-11
GR1000315B (el) 1992-06-25
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IE880697L (en) 1988-09-11
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US5989817A (en) 1999-11-23
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AU622104B2 (en) 1992-04-02
IL85480A0 (en) 1988-07-31
NL194922C (nl) 2003-07-04
SE500262C2 (sv) 1994-05-24
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SE8800864L (sv) 1988-09-12
PT86937A (pt) 1989-03-30
CA1338207C (en) 1996-04-02
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FI94429B (fi) 1995-05-31
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FI880994A (fi) 1988-09-12
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DK129588D0 (da) 1988-03-10
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IL102154A (en) 1994-04-12
FR2613077B1 (es) 1994-11-10
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US5476769A (en) 1995-12-19
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FR2613077A1 (fr) 1988-09-30
AU1193788A (en) 1988-09-15
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