NL194922B - Werkwijze voor de bepaling van nucleïnezuren, alsmede set daarvoor. - Google Patents

Werkwijze voor de bepaling van nucleïnezuren, alsmede set daarvoor.

Info

Publication number
NL194922B
NL194922B NL8800594A NL8800594A NL194922B NL 194922 B NL194922 B NL 194922B NL 8800594 A NL8800594 A NL 8800594A NL 8800594 A NL8800594 A NL 8800594A NL 194922 B NL194922 B NL 194922B
Authority
NL
Netherlands
Prior art keywords
determination
well
nucleic acids
nucleic
acids
Prior art date
Application number
NL8800594A
Other languages
English (en)
Other versions
NL8800594A (nl
NL194922C (nl
Original Assignee
Sangtec Medical Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sangtec Medical Ab filed Critical Sangtec Medical Ab
Publication of NL8800594A publication Critical patent/NL8800594A/nl
Publication of NL194922B publication Critical patent/NL194922B/nl
Application granted granted Critical
Publication of NL194922C publication Critical patent/NL194922C/nl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701—Specific hybridization probes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/686—Polymerase chain reaction [PCR]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
NL8800594A 1987-03-11 1988-03-10 Werkwijze voor de bepaling van nucleïnezuren, alsmede set daarvoor. NL194922C (nl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US2460487A 1987-03-11 1987-03-11
US2460487 1987-03-11

Publications (3)

Publication Number Publication Date
NL8800594A NL8800594A (nl) 1988-10-03
NL194922B true NL194922B (nl) 2003-03-03
NL194922C NL194922C (nl) 2003-07-04

Family

ID=21821443

Family Applications (1)

Application Number Title Priority Date Filing Date
NL8800594A NL194922C (nl) 1987-03-11 1988-03-10 Werkwijze voor de bepaling van nucleïnezuren, alsmede set daarvoor.

Country Status (25)

Country Link
US (2) US5476769A (nl)
JP (1) JP3244500B2 (nl)
AT (1) AT395434B (nl)
AU (1) AU622104B2 (nl)
BE (1) BE1003990A5 (nl)
CA (1) CA1338207C (nl)
CH (1) CH677285A5 (nl)
DD (1) DD272664A5 (nl)
DE (1) DE3807994C2 (nl)
DK (1) DK175384B1 (nl)
ES (1) ES2006377A6 (nl)
FI (1) FI94429C (nl)
FR (1) FR2613077A1 (nl)
GB (1) GB2202328B (nl)
GR (1) GR1000315B (nl)
HU (1) HU202583B (nl)
IE (1) IE61664B1 (nl)
IL (3) IL102154A (nl)
IT (1) IT1216048B (nl)
LU (1) LU87153A1 (nl)
NL (1) NL194922C (nl)
NO (1) NO172909C (nl)
NZ (1) NZ223700A (nl)
PT (1) PT86937B (nl)
SE (1) SE500262C2 (nl)

Families Citing this family (171)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5753433A (en) * 1909-12-05 1998-05-19 Boehringer Mannheim Gmbh Method for the sensitive detection of nucleic acids
DE4038804A1 (de) 1990-10-09 1992-04-16 Boehringer Mannheim Gmbh Verfahren zur genus- oder/und spezies-spezifischen detektion von bakterien in einer probenfluessigkeit
US5714380A (en) 1986-10-23 1998-02-03 Amoco Corporation Closed vessel for isolating target molecules and for performing amplification
FI80476C (fi) * 1987-10-09 1990-06-11 Orion Yhtymae Oy Foerbaettrat hybridisationsfoerfarande, vid foerfarandet anvaent redskap och reagensfoerpackning.
CA1325761C (en) * 1987-12-25 1994-01-04 Takanori Oka Method of detecting an intended nucleic acid in a sample
JPH0775560B2 (ja) * 1987-12-25 1995-08-16 湧永製薬株式会社 検体中の目的核酸の検出法
EP0406280A1 (en) * 1988-03-25 1991-01-09 Akzo Nobel N.V. Method for amplifying and detecting nucleic acid in a test liquid
US5817797A (en) * 1988-06-01 1998-10-06 The United States Of America As Represented By The Department Of Health And Human Services Sequencing DNA; a modification of the polymerase chain reaction
AU629845B2 (en) * 1988-08-30 1992-10-15 Abbott Laboratories Detection and amplification of target nucleic acid sequences
US5858652A (en) * 1988-08-30 1999-01-12 Abbott Laboratories Detection and amplification of target nucleic acid sequences
GB8827160D0 (en) * 1988-11-21 1988-12-29 Apothekernes Lab Detection & quantitative determination of rna & dna
CA2002076A1 (en) * 1988-11-21 1990-05-21 Brent A. Burdick Diagnostic kit and method using a solid phase capture means for detecting nucleic acids
IL92474A (en) * 1988-11-29 1994-04-12 Orion Yhtymae Oy Reaction method and combination for determining nucleotide sequences
US5536648A (en) * 1988-12-09 1996-07-16 Amrad Corporation Limited Amplified DNA assay using a double stranded DNA binding protein
ES2121750T3 (es) * 1988-12-09 1998-12-16 Amrad Corp Ltd Ensayo de adn amplificado.
CA2004326A1 (en) * 1988-12-23 1990-06-23 Nanibushan Dattagupta Assay of sequences using amplified genes
EP0379369B1 (en) * 1989-01-19 1996-09-04 BEHRINGWERKE Aktiengesellschaft Nucleic acid amplification using single primer
US5856092A (en) * 1989-02-13 1999-01-05 Geneco Pty Ltd Detection of a nucleic acid sequence or a change therein
JP3021036B2 (ja) * 1989-02-13 2000-03-15 ジェネコ・ピーティーワイ・リミテッド 核酸配列又はその中の変化の検出
CA2011818A1 (en) * 1989-03-17 1990-09-17 Fred T. Oakes Methods for purification, amplification and detection of a nucleic acid
CA2013317A1 (en) * 1989-04-17 1990-10-17 Fred T. Oakes Diagnostic kit, primer composition and their use for replication or detection of nucleic acids
JPH04506599A (ja) * 1989-06-12 1992-11-19 セーイーエス　ビオ　アンテルナショナル 特定の核酸配列を検出する方法及びその応用
GB8920097D0 (en) * 1989-09-06 1989-10-18 Ici Plc Amplification processes
US5196305A (en) * 1989-09-12 1993-03-23 Eastman Kodak Company Diagnostic and amplification methods using primers having thymine at 3' end to overcome primer-target mismatch at the 3' end
US5232829A (en) * 1989-09-29 1993-08-03 Hoffmann-La Roche Inc. Detection of chlamydia trachomatis by polymerase chain reaction using biotin labelled lina primers and capture probes
IL97222A (en) * 1990-02-16 1995-08-31 Orion Yhtymae Oy Method and Responder for Determining Special Changes to Nucleotide
US6013431A (en) 1990-02-16 2000-01-11 Molecular Tool, Inc. Method for determining specific nucleotide variations by primer extension in the presence of mixture of labeled nucleotides and terminators
US5387505A (en) * 1990-05-04 1995-02-07 Eastman Kodak Company Preparation and isolation of single-stranded biotinylated nucleic acids by heat avidin-biotin cleavage
NZ240079A (en) * 1990-10-09 1993-07-27 Boehringer Mannheim Gmbh Method for the detection of a nucleic acid or part thereof
EP0566670A4 (en) * 1990-12-17 1993-12-08 Idexx Laboratories, Inc. Nucleic acid sequence detection by triple helix formation
DE4106251A1 (de) * 1991-02-28 1992-09-03 Boehringer Mannheim Gmbh Nachweis von bakterien mit hilfe einer nukleinsaeureamplifikation
US6004744A (en) 1991-03-05 1999-12-21 Molecular Tool, Inc. Method for determining nucleotide identity through extension of immobilized primer
US5888819A (en) * 1991-03-05 1999-03-30 Molecular Tool, Inc. Method for determining nucleotide identity through primer extension
CA2065719A1 (en) * 1991-04-30 1992-10-31 John B. Findlay Nucleic acid amplification and detection methods using rapid polymerase chain reaction cycle
US5387510A (en) * 1991-10-02 1995-02-07 Eastman Kodak Company Detection of amplified nucleic acid using secondary capture oligonucleotides and test kit
IT1252295B (it) * 1991-11-15 1995-06-08 Schiapparelli Diagnostici Ismu Metodo per rivelare acidi nucleici e relativo kit diagnostico
JPH07502655A (ja) * 1991-12-23 1995-03-23 バイエル　コーポレイション 溶液相サンドイッチハイブリダイゼーションアッセイに用いるためのｃｍｖプローブ
US5863724A (en) * 1994-04-13 1999-01-26 Baylor College Of Medicine Methods of screening for persistent hyperinsulinemic hypoglycemia of infancy
US5658729A (en) 1994-10-11 1997-08-19 The University Of British Columbia Method, reagent and kit for evaluating susceptibility to premature atherosclerosis
DE4421901A1 (de) * 1994-06-23 1996-01-04 Bayer Ag Ein DNA-Schnelltest zum Nachweis von chinolonresistenten Staphylococcus aureus Erregern in klinischem Probenmaterial
US5705366A (en) * 1994-09-15 1998-01-06 Johnson & Johnson Clinical Diagnostics, Inc. Coamplification of target nucleic acids using volume exclusion agent in reaction composition, test kit and test device useful therefor
US5654141A (en) * 1994-11-18 1997-08-05 Thomas Jefferson University Amplification based detection of bacterial infection
US5856096A (en) * 1995-09-20 1999-01-05 Ctrc Research Foundation Rapid and sensitive assays for detecting and distinguishing between processive and non-processive telomerase activities
WO1997035033A1 (en) 1996-03-19 1997-09-25 Molecular Tool, Inc. Method for determining the nucleotide sequence of a polynucleotide
US6132954A (en) * 1996-08-20 2000-10-17 Baylor College Of Medicine Methods of screening for agents that delay a cell cycle and compositions comprising era and an analogue of wild-type era
US6043283A (en) * 1996-09-20 2000-03-28 Baylor College Of Medicine Tyramine compounds and their neuronal effects
US6071493A (en) * 1996-09-20 2000-06-06 Baylor College Of Medicine Method of screening for an agent that inhibits mononuclear phagocyte-plaque component complex formation
US6262242B1 (en) 1997-01-30 2001-07-17 Board Of Regents, The University Of Texas System Tumor suppressor designated TS10Q23.3
US6482795B1 (en) 1997-01-30 2002-11-19 Myriad Genetics, Inc. Tumor suppressor designated TS10q23.3
US6713300B1 (en) 1997-02-27 2004-03-30 University Of Utah Research Foundation Nucleic acid and amino acid sequences for ATP-binding cassette transporter and methods of screening for agents that modify ATP-binding cassette transporter
IL122147A0 (en) * 1997-11-10 1998-04-05 Technion Res & Dev Foundation Method for labeling polynucleotides
CA2314429C (en) 1997-12-18 2010-03-02 Ecogen, Inc. Insect-resistant transgenic plants and methods for improving .delta.-endotoxin activity against target insects
US6673914B1 (en) 1998-01-22 2004-01-06 John Wayne Cancer Institute Human tumor-associated gene
US20020147143A1 (en) 1998-03-18 2002-10-10 Corixa Corporation Compositions and methods for the therapy and diagnosis of lung cancer
DE19824900B4 (de) 1998-06-04 2006-05-04 Roche Diagnostics Gmbh DNA-Nachweis über einen Strangreassoziationskomplex
US6743906B1 (en) 1998-10-02 2004-06-01 Board Of Regents, The University Of Texas PPP2R1B is a tumor suppressor
US6468523B1 (en) 1998-11-02 2002-10-22 Monsanto Technology Llc Polypeptide compositions toxic to diabrotic insects, and methods of use
CA2350911A1 (en) 1998-11-16 2000-05-25 Board Of Regents, The University Of Texas System Hiv-specific t-cell induction
US6432642B1 (en) 1999-01-15 2002-08-13 Pe Corporation (Ny) Binary probe and clamp composition and methods for a target hybridization detection
US6156515A (en) 1999-02-09 2000-12-05 Urocor, Inc. Prostate-specific gene for diagnosis, prognosis and management of prostate cancer
JP2002542805A (ja) 1999-04-30 2002-12-17 ユニバーシティ オブ フロリダ アデノ随伴ウイルス送達リボザイム組成物および使用方法
WO2000073764A2 (en) 1999-06-01 2000-12-07 Baylor College Of Medicine Composition and methods for the therapeutic use of an atonal-associated sequence
US20040002068A1 (en) 2000-03-01 2004-01-01 Corixa Corporation Compositions and methods for the detection, diagnosis and therapy of hematological malignancies
WO2001081379A2 (en) 2000-04-21 2001-11-01 Corixa Corporation Compounds and methods for treatment and diagnosis of chlamydial infection
AU2001273149A1 (en) 2000-06-28 2002-01-08 Corixa Corporation Compositions and methods for the therapy and diagnosis of lung cancer
EP1325125B1 (en) 2000-07-10 2013-06-05 Board Of Regents, The University Of Texas System Chromosome 3p21.3 genes are tumor suppressors
JP2005504513A (ja) 2001-05-09 2005-02-17 コリクサ コーポレイション 前立腺癌の治療及び診断のための組成物及び方法
JP4338402B2 (ja) 2001-05-22 2009-10-07 ユニバーシティ オブ シカゴ Ｎ４ウイルス一本鎖ｄｎａ依存的ｒｎａポリメラーゼ
EP1436423A4 (en) 2001-09-19 2005-04-13 Intergenetics Inc GENETIC ANALYSIS TO STRATIFY CANCER RISK
EP1908851A3 (en) 2001-09-19 2008-06-25 Intergenetics Incorporated Genetic analysis for stratification of cancer risk
ES2205998B1 (es) * 2001-12-14 2005-08-16 Consejo Sup. Investig. Cientificas. Procedimiento para la deteccion del virus del amarilleo de las venas del pepino (cvyv).
CA2860702C (en) 2001-12-17 2019-02-26 Corixa Corporation Compositions and methods for the therapy and diagnosis of inflammatory bowel disease
US20060009409A1 (en) 2002-02-01 2006-01-12 Woolf Tod M Double-stranded oligonucleotides
EP1470148B1 (en) 2002-02-01 2012-07-18 Life Technologies Corporation Double-stranded oligonucleotides
DK1636561T3 (da) 2002-07-15 2011-05-16 Univ Texas Kombinatorisk proteinbiblioteksscreening ved hjælp af periplasmatisk ekspression
KR20120002613A (ko) 2002-08-12 2012-01-06 제네렉스, 인코포레이티드 폭스바이러스 및 암과 관련된 방법 및 조성물
AU2002951411A0 (en) 2002-09-16 2002-09-26 The University Of Sydney Genotype screen
US7960522B2 (en) 2003-01-06 2011-06-14 Corixa Corporation Certain aminoalkyl glucosaminide phosphate compounds and their use
RU2544850C2 (ru) 2003-01-06 2015-03-20 Корикса Корпорейшн Некоторые аминоалкилглюкозаминидфосфатные производные и их применение
DE602004029560D1 (de) 2003-03-07 2010-11-25 Rubicon Genomics Inc Amplifikation und analyse von gesamtgenom- und gesamttranskriptom- bibliotheken, die durch ein dns-polymerisierungsverfahren produziert wurden
US20050059024A1 (en) 2003-07-25 2005-03-17 Ambion, Inc. Methods and compositions for isolating small RNA molecules
CN1882688B (zh) 2003-07-25 2014-07-16 安比恩股份有限公司 用于分离小rna分子的方法和组合物
US20090081243A1 (en) 2004-06-03 2009-03-26 Athlomics Pty Ltd. Agents and methods for diagnosing stress
WO2006017724A1 (en) * 2004-08-06 2006-02-16 Becton, Dickinson And Company Sequences and methods for detection of cytomegalovirus
ATE469245T1 (de) 2004-09-14 2010-06-15 Univ Colorado Auf genetischem targeting basierendes verfahren zur behandlung mit bucindolol
PL1859330T3 (pl) 2005-01-28 2013-01-31 Univ Duke Urządzenia i sposoby manipulacji kropelkami na płytkach obwodów drukowanych
ES2381279T3 (es) 2005-05-06 2012-05-24 Gen-Probe Incorporated Métodos y productos para la captura de ácido nucleico diana
CA2614202A1 (en) 2005-07-07 2007-01-18 Athlomics Pty Ltd Polynucleotide marker genes and their expression, for diagnosis of endotoxemia
US7494788B2 (en) 2005-07-11 2009-02-24 Molecular Kinetics, Inc. Entropic bristle domain sequences and their use in recombinant protein production
US8980246B2 (en) 2005-09-07 2015-03-17 Sillajen Biotherapeutics, Inc. Oncolytic vaccinia virus cancer therapy
EP1945816B1 (en) 2005-10-21 2011-07-27 GeneNews Inc. Method and apparatus for correlating levels of biomarker products with disease
EP2368569A3 (en) 2006-01-18 2012-05-02 University Of Chicago Compositions and methods related to staphylococcal bacterium proteins
JP5254949B2 (ja) 2006-03-15 2013-08-07 マイクロニクス， インコーポレイテッド 一体型の核酸アッセイ
ES2741138T3 (es) 2006-09-15 2020-02-10 Childrens Hospital Of Eastern Ontario Res Institute Inc Rhabdovirus oncolítico de Farmington
CA2671264C (en) 2006-11-30 2015-11-24 Research Development Foundation Improved immunoglobulin libraries
US9938641B2 (en) * 2006-12-18 2018-04-10 Fluidigm Corporation Selection of aptamers based on geometry
DK2191001T3 (en) 2007-04-09 2016-09-19 Univ Florida RAAV VECTOR COMPOSITIONS WITH TYROSIN MODIFIED CAPSIDE PROTEINS AND PROCEDURES FOR USE THEREOF
EP2155789B1 (en) 2007-05-01 2013-07-24 Research Development Foundation Immunoglobulin fc libraries
WO2010042481A1 (en) 2008-10-06 2010-04-15 University Of Chicago Compositions and methods related to bacterial eap, emp, and/or adsa proteins
PL2414387T3 (pl) 2009-04-03 2016-06-30 Univ Chicago Kompozycje i sposoby związane z wariantami białka A (SpA)
KR101815716B1 (ko) 2009-04-22 2018-01-05 인디애나 유니버시티 리서치 앤드 테크놀로지 코퍼레이션 만성 폐쇄성 폐 질환 및 천식의 치료에 사용하기 위한 조성물
EP2449104B1 (en) 2009-06-29 2014-06-04 Luminex Corporation Chimeric primers with hairpin conformations and methods of using same
EP2272979A1 (en) 2009-06-30 2011-01-12 Centre National de la Recherche Scientifique (CNRS) Method for testing a subject thought to be predisposed to having cancer
SG10201700096VA (en) 2009-07-17 2017-02-27 Bioatla Llc Simultaneous, Integrated Selection And Evolution Of Antibody/Protein Performance And Expression In Production Hosts
US9409983B2 (en) 2009-07-23 2016-08-09 The Board Of Trustess Of The University Of Illinois Methods and compositions involving PBEF inhibitors for lung inflammation conditions and diseases
US9512481B2 (en) 2009-09-11 2016-12-06 The Regents Of The University Of Colorado, A Body Corporate Polymorphisms in the PDE3A gene
ES2671570T3 (es) 2009-09-14 2018-06-07 Sillajen Biotherapeutics, Inc. Terapia combinada contra el cáncer con virus oncolítico de vaccinia
US9045729B2 (en) 2009-12-10 2015-06-02 Ottawa Hospital Research Institute Oncolytic rhabdovirus
CA2822747A1 (en) 2009-12-23 2011-06-30 Arca Biopharma, Inc. Use of s-(6-nitro-oxi-hexahydro-furo[3,2-b]thioacetate in the treatment of cardiovascular disorders associated with oxide synthase dysfunction
KR101851117B1 (ko) 2010-01-29 2018-04-23 마이크로닉스 인코포레이티드. 샘플-투-앤서 마이크로유체 카트리지
JP2013523818A (ja) 2010-04-05 2013-06-17 ザ・ユニバーシティー・オブ・シカゴ 免疫反応のエンハンサーとしてのプロテインＡ（ＳｐＡ）抗体に関連する組成物および方法
RS58434B1 (sr) 2010-04-23 2019-04-30 Univ Florida Sastavi raav-guanilatne ciklaze i postupci tretiranja leberove urođene amauroze-1 (lca1)
KR20130093084A (ko) 2010-07-02 2013-08-21 더 유니버시티 오브 시카고 단백질 Ａ(ＳｐＡ) 변이체와 관련된 조성물 및 방법
ES2966088T3 (es) 2010-07-16 2024-04-18 Bioatla Inc Nuevos métodos de evolución de proteínas
US9095540B2 (en) 2010-09-09 2015-08-04 The University Of Chicago Methods and compositions involving protective staphylococcal antigens
EP2455485A1 (de) 2010-11-19 2012-05-23 Anagnostics Bioanalysis GmbH Verfahren zum Nachweis von Nukleinsäuren
CA2824277C (en) 2011-01-04 2021-08-31 Jennerex, Inc. Generation of antibodies to tumor antigens and generation of tumor specific complement dependent cytotoxicity by administration of oncolytic vaccinia virus
AU2012214643B2 (en) 2011-02-07 2016-12-15 Research Development Foundation Engineered immunoglobulin Fc polypeptides
US20140057295A1 (en) 2011-02-28 2014-02-27 Barbara J. Stegmann Anti-mullerian hormone changes in pregnancy and prediction of adverse pregnancy outcomes and gender
AU2012226530B2 (en) 2011-03-08 2016-12-01 King Abdullah University Of Science And Technology Molecular biomarker set for early detection of ovarian cancer
EP2694534B1 (en) 2011-04-08 2018-06-20 Evaxion Biotech ApS Proteins and nucleic acids useful in vaccines targeting staphylococcus aureus
US8945588B2 (en) 2011-05-06 2015-02-03 The University Of Chicago Methods and compositions involving protective staphylococcal antigens, such as EBH polypeptides
US9364532B2 (en) 2011-06-08 2016-06-14 Children's Hospital Of Eastern Ontario Research Institute Inc. Compositions and methods for glioblastoma treatment
JP2014527398A (ja) 2011-06-21 2014-10-16 オンコファクター コーポレイション がんの療法および診断のための組成物および方法
WO2013036799A2 (en) 2011-09-09 2013-03-14 Fred Hutchinson Cancer Research Center Methods and compositions involving nkg2d inhibitors and cancer
US9273102B2 (en) 2011-10-12 2016-03-01 Niels Iversen Møller Peptides derived from Campylobacter jejuni and their use in vaccination
EP2794904B1 (en) 2011-12-22 2017-09-06 Ibis Biosciences, Inc. Amplification of a sequence from a ribonucleic acid
US9701959B2 (en) 2012-02-02 2017-07-11 Invenra Inc. High throughput screen for biologically active polypeptides
BR112014026861A2 (pt) 2012-04-26 2018-05-15 Univ Chicago antígenos de estafilococos coagulase e métodos de seu uso
JP6248633B2 (ja) * 2012-08-31 2017-12-20 東レ株式会社 標的核酸の検出方法
EP3524691A1 (en) 2012-12-07 2019-08-14 SuppreMol GmbH Stratification and treatment of patients of idiopathic thrombocytopenic purpura
WO2014100725A1 (en) 2012-12-21 2014-06-26 Micronics, Inc. Portable fluorescence detection system and microassay cartridge
EP3549674B1 (en) 2012-12-21 2020-08-12 PerkinElmer Health Sciences, Inc. Low elasticity films for microfluidic use
US10065186B2 (en) 2012-12-21 2018-09-04 Micronics, Inc. Fluidic circuits and related manufacturing methods
US10125373B2 (en) 2013-01-22 2018-11-13 Arizona Board Of Regents On Behalf Of Arizona State University Geminiviral vector for expression of rituximab
CN105658790A (zh) 2013-02-21 2016-06-08 东安大略研究所儿童医院有限公司 疫苗组合物
JP6484222B2 (ja) 2013-05-07 2019-03-13 マイクロニクス， インコーポレイテッド 核酸の調製および分析のためのデバイス
JP6472788B2 (ja) 2013-05-07 2019-02-20 マイクロニクス， インコーポレイテッド 粘土鉱物およびアルカリ性溶液を使用して核酸含有試料を調製するための方法
EP2994750B1 (en) 2013-05-07 2020-08-12 PerkinElmer Health Sciences, Inc. Microfluidic devices and methods for performing serum separation and blood cross-matching
MX2016004283A (es) 2013-10-03 2016-10-12 Oklahoma Med Res Found Biomarcadores para la actividad, e intesidad y arrebato de la enfermedad lupus eritematoso sistemico.
US20160368952A1 (en) 2013-12-03 2016-12-22 Evaxion Biotech Aps Proteins and nucleic acids useful in vaccines targeting staphylococcus aureus
EP3447493B1 (en) 2014-01-07 2020-05-13 Bioatla, LLC Proteins targeting orthologs
WO2015191916A1 (en) 2014-06-11 2015-12-17 Micronics, Inc. Microfluidic cartridges and apparatus with integrated assay controls for analysis of nucleic acids
WO2016075305A2 (en) 2014-11-13 2016-05-19 Evaxion Biotech Aps Peptides derived from acinetobacter baumannii and their use in vaccination
EP3230314B1 (en) 2014-12-08 2023-05-03 Berg LLC Use of markers including filamin a in the diagnosis and treatment of prostate cancer
WO2016113252A2 (en) 2015-01-12 2016-07-21 Evaxion Biotech Aps Proteins and nucleic acids useful in vaccines targeting klebsiella pneumoniae
JP6724023B2 (ja) 2015-02-09 2020-07-15 リサーチ ディベロップメント ファウンデーション 改善された補体活性化を示す操作された免疫グロブリンｆｃポリペプチド
EP3070178B1 (en) 2015-03-20 2020-02-12 Albert-Ludwigs-Universität Freiburg Method for diagnosing breast cancer
EP3317295B1 (en) 2015-07-04 2022-05-18 Evaxion Biotech A/S Proteins and nucleic acids useful in vaccines targeting pseudomonas aeruginosa
MX2018000729A (es) 2015-07-17 2018-09-06 Harvard College Métodos para amplificar las secuencias de ácido nucleico.
WO2017040380A2 (en) 2015-08-28 2017-03-09 Research Development Foundation Engineered antibody fc variants
US10946084B2 (en) 2016-02-22 2021-03-16 Evaxion Biotech Aps Proteins and nucleic acids useful in vaccines targeting Staphylococcus aureus
JP7042755B2 (ja) 2016-06-05 2022-03-28 バーグ エルエルシー 患者層別化及び潜在的バイオマーカー同定のためのシステム及び方法
EP3565576A1 (en) 2017-01-05 2019-11-13 Evaxion Biotech ApS Vaccines targeting pseudomonas aeruginosa
EP3574114B1 (en) 2017-01-26 2022-06-29 Oklahoma Medical Research Foundation Biomarkers for systemic lupus erythematosus disease activity, and intensity and flare
EP3867645B1 (en) 2018-10-18 2024-06-05 Oklahoma Medical Research Foundation Biomarkers for a systemic lupus erythematosus (sle) disease activity immune index that characterizes disease activity
US20220111031A1 (en) 2018-10-22 2022-04-14 Evaxion Biotech Aps Vaccines targeting M. catharrhalis
WO2020174044A1 (en) 2019-02-27 2020-09-03 Evaxion Biotech Aps Vaccines targeting h. influenzae
US20200377951A1 (en) 2019-04-30 2020-12-03 Chondrial Therapeutics, Inc. Frataxin-sensitive markers for determining effectiveness of frataxin replacement therapy
EP3772543B1 (en) 2019-08-09 2023-09-27 Albert-Ludwigs-Universität Freiburg Method for diagnosing breast cancer
WO2021140123A1 (en) 2020-01-06 2021-07-15 Evaxion Biotech Aps Vaccines targeting neisseria gonorrhoeae
WO2022006286A1 (en) 2020-06-30 2022-01-06 Lunglife Ai Methods for detecting lung cancer
WO2022047359A1 (en) 2020-08-31 2022-03-03 Berg Llc Protein biomarkers for pancreatic cancer
IL307531A (en) 2021-04-06 2023-12-01 Bpgbio Inc Protein markers for estrogen receptor (ER)-like and estrogen receptor (ER)-negative breast cancer
EP4320440A1 (en) 2021-04-06 2024-02-14 BPGbio, Inc. Protein markers for estrogen receptor (er)-positive luminal a(la)-like and luminal b1 (lb1)-like breast cancer
CA3214833A1 (en) 2021-04-06 2022-10-13 Bpgbio, Inc. Protein markers for the prognosis of breast cancer progression
CN117915944A (zh) 2021-07-05 2024-04-19 伊沃逊生物科技股份公司 靶向淋病奈瑟氏菌的疫苗
WO2023196937A1 (en) 2022-04-06 2023-10-12 Larimar Therapeutics, Inc. Frataxin-sensitive markers for monitoring frataxin replacement therapy
WO2023230531A1 (en) 2022-05-24 2023-11-30 Lunglife Ai, Inc. Methods for detecting circulating genetically abnormal cells
WO2023240201A1 (en) 2022-06-08 2023-12-14 Larimar Therapeutics, Inc. Frataxin-sensitive markers for monitoring progression and treatment of leigh syndrome
WO2023239940A1 (en) 2022-06-10 2023-12-14 Research Development Foundation Engineered fcriib selective igg1 fc variants and uses thereof

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2422956A1 (fr) * 1978-04-13 1979-11-09 Pasteur Institut Procede de detection et de caracterisation d'un acide nucleique ou d'une sequence de celui-ci, et reactif enzymatique pour la mise en oeuvre de ce procede
US4302204A (en) * 1979-07-02 1981-11-24 The Board Of Trustees Of Leland Stanford Junior University Transfer and detection of nucleic acids
FI63596C (fi) * 1981-10-16 1983-07-11 Orion Yhtymae Oy Mikrobdiagnostiskt foerfarande som grundar sig pao skiktshybridisering av nukleinsyror och vid foerfarandet anvaenda kombinationer av reagenser
BG36086A1 (en) * 1982-01-19 1984-09-14 Glbov Method for inducing interferon
CA1223831A (en) * 1982-06-23 1987-07-07 Dean Engelhardt Modified nucleotides, methods of preparing and utilizing and compositions containing the same
US4605735A (en) * 1983-02-14 1986-08-12 Wakunaga Seiyaku Kabushiki Kaisha Oligonucleotide derivatives
CA1256005A (en) * 1983-09-26 1989-06-20 W. Peter Hansen Sandwich hybridization method for nucleic acid detection
US4749647A (en) * 1984-06-22 1988-06-07 Genetic Systems Corporation Polymerization-induced separation assay using recognition pairs
US4743562A (en) * 1984-08-21 1988-05-10 The Board Of Trustees Of The Leland Stanford Junior University Purified human cytomegalovirus protein
US4563417A (en) * 1984-08-31 1986-01-07 Miles Laboratories, Inc. Nucleic acid hybridization assay employing antibodies to intercalation complexes
US4883750A (en) * 1984-12-13 1989-11-28 Applied Biosystems, Inc. Detection of specific sequences in nucleic acids
FI72146C (fi) * 1985-01-02 1987-04-13 Orion Yhtymae Oy Foerfarande foer identifiering av nukleinsyror.
CA1272443A (en) * 1985-02-22 1990-08-07 Nanibhushan Dattagupta Solution-phase dual hybridization assay for detecting polynucleotide sequences
CA1278755C (en) * 1985-03-15 1991-01-08 William J. Knowles Labelling of oligonucleotides
ES8706823A1 (es) * 1985-03-28 1987-06-16 Cetus Corp Un procedimiento para detectar la presencia o ausencia de al menos una secuencia especifica de acidos nucleicos en una muestra
US4683202A (en) * 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
GB8509367D0 (en) * 1985-04-12 1985-05-15 Amersham Int Plc Nucleic acid hybridisation
US4751177A (en) * 1985-06-13 1988-06-14 Amgen Methods and kits for performing nucleic acid hybridization assays
GB8515276D0 (en) * 1985-06-17 1985-07-17 Amersham Int Plc Nucleic acid sequencing
CA1284931C (en) * 1986-03-13 1991-06-18 Henry A. Erlich Process for detecting specific nucleotide variations and genetic polymorphisms present in nucleic acids
AU7015287A (en) * 1986-03-19 1987-09-24 Cetus Corporation Detection of nucleic acid sequence using liquid hybridization method
US4851331A (en) * 1986-05-16 1989-07-25 Allied Corporation Method and kit for polynucleotide assay including primer-dependant DNA polymerase

Also Published As

Publication number Publication date
FI94429B (fi) 1995-05-31
DE3807994C2 (de) 1998-08-27
IE61664B1 (en) 1994-11-16
NZ223700A (en) 1990-04-26
JPS63243875A (ja) 1988-10-11
AU622104B2 (en) 1992-04-02
GR1000315B (el) 1992-06-25
SE8800864D0 (sv) 1988-03-10
ES2006377A6 (es) 1989-04-16
PT86937B (pt) 1995-03-01
GB2202328B (en) 1991-07-03
DK129588D0 (da) 1988-03-10
NL8800594A (nl) 1988-10-03
DK129588A (da) 1988-09-12
FR2613077A1 (fr) 1988-09-30
US5989817A (en) 1999-11-23
FR2613077B1 (nl) 1994-11-10
DE3807994A1 (de) 1988-09-22
IL102154A0 (en) 1993-01-14
NO172909B (no) 1993-06-14
NO881064D0 (no) 1988-03-10
IL102154A (en) 1994-04-12
JP3244500B2 (ja) 2002-01-07
GB2202328A (en) 1988-09-21
PT86937A (pt) 1989-03-30
CA1338207C (en) 1996-04-02
HUT50868A (en) 1990-03-28
HU202583B (en) 1991-03-28
AT395434B (de) 1992-12-28
LU87153A1 (fr) 1988-08-23
IT1216048B (it) 1990-02-22
GR880100139A (en) 1989-01-31
AU1193788A (en) 1988-09-15
NO172909C (no) 1993-09-22
IL85480A0 (en) 1988-07-31
FI880994A0 (fi) 1988-03-03
SE8800864L (sv) 1988-09-12
GB8805681D0 (en) 1988-04-07
BE1003990A5 (fr) 1992-07-28
NO881064L (no) 1988-09-12
IT8819722A0 (it) 1988-03-10
US5476769A (en) 1995-12-19
IE880697L (en) 1988-09-11
DD272664A5 (de) 1989-10-18
FI94429C (fi) 1995-09-11
FI880994A (fi) 1988-09-12
CH677285A5 (nl) 1991-04-30
DK175384B1 (da) 2004-09-20
ATA64388A (de) 1992-05-15
NL194922C (nl) 2003-07-04
SE500262C2 (sv) 1994-05-24

Similar Documents

Publication Publication Date Title
NL194922B (nl) Werkwijze voor de bepaling van nucleïnezuren, alsmede set daarvoor.
NL189427C (nl) Werkwijze voor het identificeren van nucleinezuren.
NL192986B (nl) Werkwijze voor het bereiden van 1,4-dihydro-4-oxo-naftyridinederivaten.
NL193945B (nl) Werkwijze voor het bereiden van 4-amino-1-hydroxy-butaan-1,1-difosfonzuur en 6-amino-1-hydroxy-hexaan-1,1-difosfonzuur.
NL192157B (nl) Werkwijze voor de vervaardiging van een inductantie-element.
NL187486C (nl) Werkwijze voor de hydroxy-alkylering van een polysaccharide.
DE3881058D1 (de) Verfahren zur mesophase-peche-herstellung.
NL189516C (nl) Werkwijze voor het bereiden van roet.
NL194042B (nl) Werkwijze voor de bereiding van 3-fenyl-4-cyaanpyrrolen.
NL191358C (nl) Werkwijze voor de plaatsinstelling van gereedschappen.
NL194204B (nl) Werkwijze voor de bereiding van een tussenproduct van Diltiazem.
NL194001B (nl) Werkwijze voor bereiden van gesubstitueerd benzaldehyde.
NL8600136A (nl) Werkwijze voor het bereiden van 4,4-dialkyl-2-azetidinonen.
DE3784792D1 (de) Biochemisches verfahren.
DE58901165D1 (de) Verfahren zur herstellung von 2,4-dihydroxybenzoesaeure.
NL189253C (nl) Werkwijze voor de bereiding van 2-mercapto-1-ethanol.
NL193346B (nl) Werkwijze voor het verbeteren van de bedrijfsefficiëntie van een drukverhogingsinstallatie.
NL193407B (nl) Werkwijze voor de bereiding van 3-exomethyleencefamderivaten.
NL187013C (nl) Werkwijze voor het bereiden van isobutyrylfluoride.
NL193866B (nl) Werkwijze voor het bereiden van isobuteen.
NL191414C (nl) Werkwijze voor de bereiding van een 1-fenyl-3-carbalkoxy-5-hydroxypyrazool.
NL184274C (nl) Werkwijze voor de bereiding van 7-alfa-acylthio-4-een-3-oxosteroiden.
NL192117B (nl) Werkwijze voor het bereiden van L-serine.
NL187626C (nl) Werkwijze voor het bereiden van isobutyrylfluoride.
DE58908915D1 (de) Verfahren zur Herstellung von 2-Chlor-5-chlormethylpyridin.

Legal Events

Date Code Title Description
BA A request for search or an international-type search has been filed
BB A search report has been drawn up
BC A request for examination has been filed
CNR Transfer of rights (patent application after its laying open for public inspection)

Free format text: SANGTEC MEDICAL AB

CNR Transfer of rights (patent application after its laying open for public inspection)

Owner name: SANGTEC MOLECULAR DIAGNOSTICS AB

V4 Discontinued because of reaching the maximum lifetime of a patent

Effective date: 20080310