SK288059B6 - Medium for protein-free and serum-free cultivation of mammalian cells, its use, process for cultivation of mammalian cells, process for production of protein, cell culture and process for production of medium for cell culture - Google Patents
Medium for protein-free and serum-free cultivation of mammalian cells, its use, process for cultivation of mammalian cells, process for production of protein, cell culture and process for production of medium for cell culture Download PDFInfo
- Publication number
- SK288059B6 SK288059B6 SK400-2002A SK4002002A SK288059B6 SK 288059 B6 SK288059 B6 SK 288059B6 SK 4002002 A SK4002002 A SK 4002002A SK 288059 B6 SK288059 B6 SK 288059B6
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- Slovakia
- Prior art keywords
- medium
- cells
- protein
- free
- serum
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/0018—Culture media for cell or tissue culture
- C12N5/0043—Medium free of human- or animal-derived components
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/745—Blood coagulation or fibrinolysis factors
- C07K14/755—Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/0018—Culture media for cell or tissue culture
- C12N5/0037—Serum-free medium, which may still contain naturally-sourced components
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/0018—Culture media for cell or tissue culture
- C12N5/005—Protein-free medium
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0681—Cells of the genital tract; Non-germinal cells from gonads
- C12N5/0682—Cells of the female genital tract, e.g. endometrium; Non-germinal cells from ovaries, e.g. ovarian follicle cells
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/05—Inorganic components
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/30—Organic components
- C12N2500/32—Amino acids
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/30—Organic components
- C12N2500/38—Vitamins
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/30—Organic components
- C12N2500/46—Amines, e.g. putrescine
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/60—Buffer, e.g. pH regulation, osmotic pressure
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/70—Undefined extracts
- C12N2500/76—Undefined extracts from plants
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/90—Serum-free medium, which may still contain naturally-sourced components
- C12N2500/92—Medium free of human- or animal-derived components
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Reproductive Health (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biophysics (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AT0165999A AT409379B (de) | 1999-06-02 | 1999-09-28 | Medium zur protein- und serumfreien kultivierung von zellen |
PCT/EP2000/009453 WO2001023527A1 (en) | 1999-09-28 | 2000-09-27 | Medium for the protein-free and serum-free cultivation of cells |
Publications (2)
Publication Number | Publication Date |
---|---|
SK4002002A3 SK4002002A3 (en) | 2002-07-02 |
SK288059B6 true SK288059B6 (sk) | 2013-03-01 |
Family
ID=3518214
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SK400-2002A SK288059B6 (sk) | 1999-09-28 | 2000-09-27 | Medium for protein-free and serum-free cultivation of mammalian cells, its use, process for cultivation of mammalian cells, process for production of protein, cell culture and process for production of medium for cell culture |
Country Status (21)
Country | Link |
---|---|
US (6) | US20030203448A1 (de) |
EP (1) | EP1220893B2 (de) |
JP (6) | JP5441288B2 (de) |
CN (2) | CN1318577C (de) |
AT (2) | AT409379B (de) |
AU (1) | AU780791B2 (de) |
CA (1) | CA2385299A1 (de) |
CY (1) | CY1106135T1 (de) |
CZ (1) | CZ305307B6 (de) |
DE (1) | DE60028989T3 (de) |
DK (1) | DK1220893T4 (de) |
ES (1) | ES2265991T5 (de) |
HU (1) | HU228210B1 (de) |
IL (4) | IL148642A0 (de) |
PL (1) | PL215234B1 (de) |
PT (1) | PT1220893E (de) |
RU (3) | RU2266325C2 (de) |
SI (1) | SI1220893T1 (de) |
SK (1) | SK288059B6 (de) |
TR (1) | TR200200757T2 (de) |
WO (1) | WO2001023527A1 (de) |
Families Citing this family (71)
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US6475725B1 (en) | 1997-06-20 | 2002-11-05 | Baxter Aktiengesellschaft | Recombinant cell clones having increased stability and methods of making and using the same |
AT409379B (de) | 1999-06-02 | 2002-07-25 | Baxter Ag | Medium zur protein- und serumfreien kultivierung von zellen |
EP1453948A2 (de) * | 2001-11-28 | 2004-09-08 | Sandoz Gmbh | Prozess für zellkultur |
US7195905B2 (en) | 2001-12-10 | 2007-03-27 | Baxter Healthcare S.A. | Enveloped virus vaccine and method for production |
JP3916516B2 (ja) * | 2002-06-10 | 2007-05-16 | 独立行政法人科学技術振興機構 | 硬組織−軟組織界面再生用足場材料 |
EP1520008B1 (de) * | 2002-07-09 | 2012-09-05 | Baxter International Inc. | Tierproteinfreies zellkulturmedium |
AU2004312352B2 (en) * | 2003-12-19 | 2010-08-19 | Wyeth | Serum-free vero cell banking process |
AU2005217154B2 (en) * | 2004-03-01 | 2010-02-18 | Ares Trading S.A. | Use of a serum-free cell culture medium for the production of IL-18BP in mammalian cells |
CA2585547A1 (en) * | 2004-10-29 | 2006-05-11 | Centocor, Inc. | Chemically defined media compositions |
US20060094104A1 (en) | 2004-10-29 | 2006-05-04 | Leopold Grillberger | Animal protein-free media for cultivation of cells |
AU2011221414B2 (en) * | 2004-10-29 | 2012-09-20 | Takeda Pharmaceutical Company Limited | Animal Protein-Free Media for Cultivation of Cells |
FR2879214A1 (fr) | 2004-12-14 | 2006-06-16 | Pierre Fabre Medicament Sa | Fractions peptidiques favorisant la croissance et la synthese de produit(s) d'interet en culture de cellules et/ou de tissus |
JP5523674B2 (ja) * | 2005-02-11 | 2014-06-18 | ノボ ノルディスク ヘルス ケア アクチェンゲゼルシャフト | 植物タンパク質加水分解産物を含有する血清フリーの細胞培養液におけるポリペプチドの生産 |
CA2601006C (en) * | 2005-03-10 | 2012-10-23 | Kyoritsu Seiyaku Corporation | Cell strain capable of being cultured without ingredients derived from animals, method of producing the same, method of producing virus using the same, and method of producing vaccine |
EP1707634A1 (de) | 2005-03-29 | 2006-10-04 | Octapharma AG | Verfahren zur Isolierung von rekombinant hergestellten Proteinen |
KR100670105B1 (ko) | 2005-06-29 | 2007-01-17 | 주식회사 셀트리온 | 콩가수분해물의 저분자량 분획을 이용하여 시알산 함량이증가된 에리스로포이에틴을 생산하는 방법 및 그에 의하여생산된 시알산 함량이 증가된 에리스로포이에틴 |
US7375188B2 (en) * | 2005-07-29 | 2008-05-20 | Mallinckrodt Baker, Inc. | Vegetarian protein a preparation and methods thereof |
PL2522717T3 (pl) * | 2006-01-04 | 2014-08-29 | Baxalta Inc | Pożywki do hodowli komórkowych wolne od oligopeptydów |
CN101501216B (zh) * | 2006-03-06 | 2013-10-02 | 胡玛基因公司 | 制备重组人凝血酶的方法 |
EP2500416A1 (de) | 2006-09-13 | 2012-09-19 | Abbott Laboratories | Verbesserungen an Zellkulturen |
MY161866A (en) | 2006-09-13 | 2017-05-15 | Abbvie Inc | Cell culture improvements |
US20100075415A1 (en) * | 2006-11-13 | 2010-03-25 | Schering Corporation | Method for reducing protease activity in plant hydrolysate |
US20090294288A1 (en) | 2006-12-11 | 2009-12-03 | Schering Corporation | High-sensitivity proteolysis assay |
EP1988101A1 (de) | 2007-05-04 | 2008-11-05 | Novo Nordisk A/S | Verbesserung von Faktor-VIII-Polypeptid-Titern in Zellkulturen |
WO2008153366A2 (en) | 2007-06-15 | 2008-12-18 | Mogam Biotechnology Research Institute | Method for manufacturing active recombinant blood coagulation factor ix |
WO2009115495A1 (de) * | 2008-03-19 | 2009-09-24 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Methode zur steigerung der reklonierungseffizienz |
EP2345713A4 (de) | 2008-04-18 | 2012-07-11 | Shanghai Nat Engineering Res Ct Of Antibody Medicine Co Ltd | Konzentrierte kulturlösung und anwendungsverfahren dafür |
TW201012930A (en) | 2008-06-16 | 2010-04-01 | Intervet Int Bv | Method of replicating viruses in suspension |
JP5458536B2 (ja) * | 2008-09-17 | 2014-04-02 | 不二製油株式会社 | 乳酸の製造方法及び乳酸発酵用添加剤 |
NZ591651A (en) * | 2008-09-26 | 2012-12-21 | Merck Sharp & Dohme | High titer antibody production and culture media comprising glucose, soy or wheat hydrolsyate, amino acids, and other chemical compounds |
PT2356247E (pt) | 2008-11-12 | 2015-10-26 | Baxalta Inc | Método de produção de fator vii isento de soro e de insulina |
US9051544B2 (en) | 2008-12-30 | 2015-06-09 | Baxter International Inc. | Method of enhancing cell growth using alkyl-amine-n-oxide (AANOx) |
CN101603026B (zh) * | 2009-06-19 | 2011-01-19 | 华东理工大学 | 适于动物细胞产品生产的无动物来源低蛋白培养基 |
CA2769361A1 (en) | 2009-07-31 | 2011-02-03 | Baxter International Inc. | Cell culture medium for adamts protein expression |
CN102115728B (zh) * | 2009-12-31 | 2012-09-26 | 北京清大天一科技有限公司 | 无血清动物细胞培养基干粉、液体培养基及其制备方法 |
RU2644651C2 (ru) * | 2010-04-26 | 2018-02-13 | Новартис Аг | Среда для культивирования клеток |
PT2563906T (pt) | 2010-04-26 | 2018-02-16 | Novartis Ag | Processo para cultivo de células cho |
BR112013000515B1 (pt) | 2010-07-08 | 2021-11-03 | Takeda Pharmaceutical Company Limited | Método para produzir uma composição de fator von willebrand recombinante (rvwf) |
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CN103160458A (zh) * | 2011-12-15 | 2013-06-19 | 西南民族大学 | 一种适合Vero细胞生长的低血清培养基 |
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AR095196A1 (es) | 2013-03-15 | 2015-09-30 | Regeneron Pharma | Medio de cultivo celular libre de suero |
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TW202204596A (zh) * | 2014-06-06 | 2022-02-01 | 美商健臻公司 | 灌注培養方法及其用途 |
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TW202330904A (zh) | 2015-08-04 | 2023-08-01 | 美商再生元醫藥公司 | 補充牛磺酸之細胞培養基及用法 |
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JP6258536B1 (ja) | 2017-03-03 | 2018-01-10 | 協和発酵キリン株式会社 | ダルベポエチン組成物の製造方法およびダルべポエチン産生細胞の培養方法 |
KR102659791B1 (ko) * | 2017-07-06 | 2024-04-23 | 리제너론 파마슈티칼스 인코포레이티드 | 당단백질을 만들기 위한 세포 배양 과정 |
CN113151183A (zh) * | 2021-04-21 | 2021-07-23 | 赵峻岭 | 一种促进蛋白表达的培养基添加物及其应用 |
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