CY1106135T1 - Μεσο για την ελευθepη απο πρωτεϊνη και ελευθepη απο ορο καλλιεργεια κυτταρων - Google Patents
Μεσο για την ελευθepη απο πρωτεϊνη και ελευθepη απο ορο καλλιεργεια κυτταρωνInfo
- Publication number
- CY1106135T1 CY1106135T1 CY20061101076T CY061101076T CY1106135T1 CY 1106135 T1 CY1106135 T1 CY 1106135T1 CY 20061101076 T CY20061101076 T CY 20061101076T CY 061101076 T CY061101076 T CY 061101076T CY 1106135 T1 CY1106135 T1 CY 1106135T1
- Authority
- CY
- Cyprus
- Prior art keywords
- free
- serum
- protein
- culture medium
- cell culture
- Prior art date
Links
- 239000006143 cell culture medium Substances 0.000 title 1
- 210000004027 cell Anatomy 0.000 abstract 1
- 210000004962 mammalian cell Anatomy 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/0018—Culture media for cell or tissue culture
- C12N5/0043—Medium free of human- or animal-derived components
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/745—Blood coagulation or fibrinolysis factors
- C07K14/755—Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/0018—Culture media for cell or tissue culture
- C12N5/0037—Serum-free medium, which may still contain naturally-sourced components
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/0018—Culture media for cell or tissue culture
- C12N5/005—Protein-free medium
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0681—Cells of the genital tract; Non-germinal cells from gonads
- C12N5/0682—Cells of the female genital tract, e.g. endometrium; Non-germinal cells from ovaries, e.g. ovarian follicle cells
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/05—Inorganic components
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/30—Organic components
- C12N2500/32—Amino acids
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/30—Organic components
- C12N2500/38—Vitamins
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/30—Organic components
- C12N2500/46—Amines, e.g. putrescine
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/60—Buffer, e.g. pH regulation, osmotic pressure
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/70—Undefined extracts
- C12N2500/76—Undefined extracts from plants
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/90—Serum-free medium, which may still contain naturally-sourced components
- C12N2500/92—Medium free of human- or animal-derived components
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Reproductive Health (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biophysics (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Abstract
Εδώ περιγράφεται ένα μέσο για την ελεύθερη από πρωτεΐνη και ελεύθερη από ορό καλλιέργεια κυττάρων, ιδιαίτερα κυττάρων θηλαστικού, διά της οποίας το μέσο περιέχει μια αναλογία υδρολύματος σόγιας.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AT0165999A AT409379B (de) | 1999-06-02 | 1999-09-28 | Medium zur protein- und serumfreien kultivierung von zellen |
PCT/EP2000/009453 WO2001023527A1 (en) | 1999-09-28 | 2000-09-27 | Medium for the protein-free and serum-free cultivation of cells |
Publications (1)
Publication Number | Publication Date |
---|---|
CY1106135T1 true CY1106135T1 (el) | 2011-06-08 |
Family
ID=3518214
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CY20061101076T CY1106135T1 (el) | 1999-09-28 | 2006-07-31 | Μεσο για την ελευθepη απο πρωτεϊνη και ελευθepη απο ορο καλλιεργεια κυτταρων |
Country Status (21)
Country | Link |
---|---|
US (6) | US20030203448A1 (el) |
EP (1) | EP1220893B2 (el) |
JP (6) | JP5441288B2 (el) |
CN (2) | CN1318577C (el) |
AT (2) | AT409379B (el) |
AU (1) | AU780791B2 (el) |
CA (1) | CA2385299A1 (el) |
CY (1) | CY1106135T1 (el) |
CZ (1) | CZ305307B6 (el) |
DE (1) | DE60028989T3 (el) |
DK (1) | DK1220893T4 (el) |
ES (1) | ES2265991T5 (el) |
HU (1) | HU228210B1 (el) |
IL (4) | IL148642A0 (el) |
PL (1) | PL215234B1 (el) |
PT (1) | PT1220893E (el) |
RU (3) | RU2266325C2 (el) |
SI (1) | SI1220893T1 (el) |
SK (1) | SK288059B6 (el) |
TR (1) | TR200200757T2 (el) |
WO (1) | WO2001023527A1 (el) |
Families Citing this family (71)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6475725B1 (en) | 1997-06-20 | 2002-11-05 | Baxter Aktiengesellschaft | Recombinant cell clones having increased stability and methods of making and using the same |
AT409379B (de) | 1999-06-02 | 2002-07-25 | Baxter Ag | Medium zur protein- und serumfreien kultivierung von zellen |
CA2466881A1 (en) * | 2001-11-28 | 2003-06-05 | Sandoz Gmbh | Cell culture process |
US7195905B2 (en) | 2001-12-10 | 2007-03-27 | Baxter Healthcare S.A. | Enveloped virus vaccine and method for production |
JP3916516B2 (ja) * | 2002-06-10 | 2007-05-16 | 独立行政法人科学技術振興機構 | 硬組織−軟組織界面再生用足場材料 |
EP1520008B1 (en) | 2002-07-09 | 2012-09-05 | Baxter International Inc. | Animal protein free media for cultivation of cells |
CA2548162C (en) * | 2003-12-19 | 2013-10-29 | Wyeth | Serum-free vero cell banking process |
ME01218B (me) | 2004-03-01 | 2013-06-20 | Ares Trading Sa | Upotreba podloge za ćelijsku strukturu bez sadrzaja seruma za produkciju il-18bp u ćelijama sisara |
US20060094104A1 (en) | 2004-10-29 | 2006-05-04 | Leopold Grillberger | Animal protein-free media for cultivation of cells |
AU2011221414B2 (en) * | 2004-10-29 | 2012-09-20 | Takeda Pharmaceutical Company Limited | Animal Protein-Free Media for Cultivation of Cells |
CA2585547A1 (en) * | 2004-10-29 | 2006-05-11 | Centocor, Inc. | Chemically defined media compositions |
FR2879214A1 (fr) * | 2004-12-14 | 2006-06-16 | Pierre Fabre Medicament Sa | Fractions peptidiques favorisant la croissance et la synthese de produit(s) d'interet en culture de cellules et/ou de tissus |
WO2006084826A1 (en) | 2005-02-11 | 2006-08-17 | Novo Nordisk Health Care Ag | Production of a polypeptide in a serum-free cell culture liquid containing plant protein hydrolysate |
EP1862537B1 (en) * | 2005-03-10 | 2013-05-08 | Kyoritsu Seiyaku Corporation | Cell line culturable without aminal-derived component, method for establishment thereof, method for production of virus using the cell line and method for production of vaccine |
EP1707634A1 (en) | 2005-03-29 | 2006-10-04 | Octapharma AG | Method for isolation of recombinantly produced proteins |
KR100670105B1 (ko) | 2005-06-29 | 2007-01-17 | 주식회사 셀트리온 | 콩가수분해물의 저분자량 분획을 이용하여 시알산 함량이증가된 에리스로포이에틴을 생산하는 방법 및 그에 의하여생산된 시알산 함량이 증가된 에리스로포이에틴 |
US7375188B2 (en) * | 2005-07-29 | 2008-05-20 | Mallinckrodt Baker, Inc. | Vegetarian protein a preparation and methods thereof |
PL3121266T3 (pl) | 2006-01-04 | 2020-07-13 | Baxalta Incorporated | Wolne od oligopeptydów pożywki do hodowli komórkowej |
CA2644926A1 (en) * | 2006-03-06 | 2007-09-13 | Humagene, Inc. | A method for the preparation of recombinant human thrombin and fibrinogen |
SG174804A1 (el) | 2006-09-13 | 2011-10-28 | Abbott Lab | |
EP2500415A1 (en) | 2006-09-13 | 2012-09-19 | Abbott Laboratories | Cell culture improvements |
EP2084265A2 (en) * | 2006-11-13 | 2009-08-05 | Schering Corporation | Method for reducing protease activity in plant hydrolysate |
US20090294288A1 (en) | 2006-12-11 | 2009-12-03 | Schering Corporation | High-sensitivity proteolysis assay |
EP1988101A1 (en) * | 2007-05-04 | 2008-11-05 | Novo Nordisk A/S | Improvement of factor VIII polypeptide titers in cell cultures |
KR101190605B1 (ko) | 2007-06-15 | 2012-10-15 | 재단법인 목암생명공학연구소 | 활성형 재조합 혈액응고 9인자의 대량생산 방법 |
WO2009115495A1 (de) * | 2008-03-19 | 2009-09-24 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Methode zur steigerung der reklonierungseffizienz |
WO2009127098A1 (zh) | 2008-04-18 | 2009-10-22 | 上海中信国健药业有限公司 | 一种浓缩培养液及其使用方法 |
TW201012930A (en) | 2008-06-16 | 2010-04-01 | Intervet Int Bv | Method of replicating viruses in suspension |
JP5458536B2 (ja) * | 2008-09-17 | 2014-04-02 | 不二製油株式会社 | 乳酸の製造方法及び乳酸発酵用添加剤 |
CA2737580A1 (en) * | 2008-09-26 | 2010-04-01 | Schering Corporation | High titer antibody production |
EP2356247B2 (en) * | 2008-11-12 | 2019-05-15 | Baxalta Incorporated | Method of producing serum-free insulin-free factor vii |
KR101737645B1 (ko) | 2008-12-30 | 2017-05-18 | 박스알타 인코퍼레이티드 | 알킬-아민-n-옥시드 (aanox)를 사용하는 세포 성장 증진 방법 |
CN101603026B (zh) * | 2009-06-19 | 2011-01-19 | 华东理工大学 | 适于动物细胞产品生产的无动物来源低蛋白培养基 |
KR101574056B1 (ko) | 2009-07-31 | 2015-12-02 | 백스터 인터내셔널 인코포레이티드 | Adamts 단백질 발현을 위한 세포 배양 배지 |
CN102115728B (zh) * | 2009-12-31 | 2012-09-26 | 北京清大天一科技有限公司 | 无血清动物细胞培养基干粉、液体培养基及其制备方法 |
AU2011246502B2 (en) | 2010-04-26 | 2014-08-28 | Novartis Ag | Improved cell cultivation process |
SG185038A1 (en) * | 2010-04-26 | 2012-11-29 | Novartis Ag | Improved cell culture medium |
TWI670073B (zh) | 2010-07-08 | 2019-09-01 | 美商巴克斯歐塔公司 | 在細胞培養物中生產重組高分子量vWF的方法 |
CN101914485A (zh) * | 2010-08-05 | 2010-12-15 | 乐能生物工程股份有限公司 | 一种无血清大豆蛋白肽动物细胞培养基的配制方法 |
KR20130101034A (ko) | 2010-08-31 | 2013-09-12 | 프리슬랜드 브랜즈 비브이 | 진핵 세포를 위한 배양 배지 |
CN103154233A (zh) * | 2010-10-05 | 2013-06-12 | 诺沃—诺迪斯克保健股份有限公司 | 生产蛋白质的方法 |
WO2012149197A2 (en) | 2011-04-27 | 2012-11-01 | Abbott Laboratories | Methods for controlling the galactosylation profile of recombinantly-expressed proteins |
CN103160458A (zh) * | 2011-12-15 | 2013-06-19 | 西南民族大学 | 一种适合Vero细胞生长的低血清培养基 |
JP2015509376A (ja) * | 2012-03-08 | 2015-03-30 | フリーズランド ブランズ ビー.ブイ. | 真核細胞のための培養培地 |
US9067990B2 (en) | 2013-03-14 | 2015-06-30 | Abbvie, Inc. | Protein purification using displacement chromatography |
WO2013158279A1 (en) | 2012-04-20 | 2013-10-24 | Abbvie Inc. | Protein purification methods to reduce acidic species |
US9181572B2 (en) | 2012-04-20 | 2015-11-10 | Abbvie, Inc. | Methods to modulate lysine variant distribution |
US9512214B2 (en) | 2012-09-02 | 2016-12-06 | Abbvie, Inc. | Methods to control protein heterogeneity |
EP2830651A4 (en) | 2013-03-12 | 2015-09-02 | Abbvie Inc | HUMAN ANTIBODIES THAT BIND TNF-ALPHA AND PREPARATION METHODS |
US9499614B2 (en) | 2013-03-14 | 2016-11-22 | Abbvie Inc. | Methods for modulating protein glycosylation profiles of recombinant protein therapeutics using monosaccharides and oligosaccharides |
US9017687B1 (en) | 2013-10-18 | 2015-04-28 | Abbvie, Inc. | Low acidic species compositions and methods for producing and using the same using displacement chromatography |
AR095196A1 (es) | 2013-03-15 | 2015-09-30 | Regeneron Pharma | Medio de cultivo celular libre de suero |
US9598667B2 (en) | 2013-10-04 | 2017-03-21 | Abbvie Inc. | Use of metal ions for modulation of protein glycosylation profiles of recombinant proteins |
US9181337B2 (en) | 2013-10-18 | 2015-11-10 | Abbvie, Inc. | Modulated lysine variant species compositions and methods for producing and using the same |
US9085618B2 (en) | 2013-10-18 | 2015-07-21 | Abbvie, Inc. | Low acidic species compositions and methods for producing and using the same |
CN104593317B (zh) * | 2013-10-31 | 2018-05-04 | 中国食品发酵工业研究院 | 一种用于细胞培养基的大豆活性肽添加剂 |
WO2015073884A2 (en) | 2013-11-15 | 2015-05-21 | Abbvie, Inc. | Glycoengineered binding protein compositions |
SG11201605146VA (en) | 2013-12-30 | 2016-07-28 | Baxalta GmbH | A method of predicting a performance characteristic of a plant or yeast hydrolysate and its use |
RU2558253C1 (ru) * | 2014-02-10 | 2015-07-27 | Федеральное Казенное Предприятие " Щелковский Биокомбинат" | Питательная среда для суспензионного культивирования клеток млекопитающих |
ES2909630T3 (es) | 2014-06-04 | 2022-05-09 | Amgen Inc | Métodos de recolección en cultivos de células de mamífero |
TWI743024B (zh) | 2014-06-06 | 2021-10-21 | 美商健臻公司 | 灌注培養方法及其用途 |
CN104560893B (zh) * | 2015-01-30 | 2017-11-14 | 肇庆大华农生物药品有限公司 | 一种用于培养病毒的培养基及其制备方法 |
RU2588666C1 (ru) * | 2015-03-23 | 2016-07-10 | Федеральное государственное бюджетное научное учреждение "Всероссийский научно-исследовательский и технологический институт биологической промышленности" | Компонент питательной среды для культивирования клеток млекопитающих |
CN105002242A (zh) * | 2015-07-23 | 2015-10-28 | 苏州康聚生物科技有限公司 | 用于cho细胞中高效表达重组人促甲状腺激素的无血清培养基及其应用 |
EP3328403A4 (en) * | 2015-07-31 | 2019-04-17 | Zen-Bio, Inc. | EXOSOME COMPOSITIONS AND USE THEREOF FOR SOFTWARE SAVING |
TW202340452A (zh) | 2015-08-04 | 2023-10-16 | 美商再生元醫藥公司 | 補充牛磺酸之細胞培養基及用法 |
US11070703B2 (en) * | 2016-07-29 | 2021-07-20 | Robert Bosch Tool Corporation | 3D printer touchscreen interface lockout |
JP6258536B1 (ja) | 2017-03-03 | 2018-01-10 | 協和発酵キリン株式会社 | ダルベポエチン組成物の製造方法およびダルべポエチン産生細胞の培養方法 |
SG11201912548XA (en) * | 2017-07-06 | 2020-01-30 | Regeneron Pharma | Cell culture process for making a glycoprotein |
CN113151183A (zh) * | 2021-04-21 | 2021-07-23 | 赵峻岭 | 一种促进蛋白表达的培养基添加物及其应用 |
WO2024024671A1 (ja) * | 2022-07-27 | 2024-02-01 | 不二製油グループ本社株式会社 | 動物細胞増殖促進剤 |
Family Cites Families (73)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AT165999B (de) | 1947-06-26 | 1950-05-25 | Delle Atel Const Electr | Einirchtung zum Schutz von Drehstrommotoren gegen Überstrom |
FR2196386A1 (en) | 1972-08-17 | 1974-03-15 | Cudennec Alain | Culture media selection - for identification of unknown bacteria |
US4443540A (en) | 1980-05-09 | 1984-04-17 | University Of Illinois Foundation | Protein hydrolysis |
DK207980A (da) * | 1980-05-13 | 1981-11-14 | Novo Industri As | Fremgangsmaade til fremstilling af et skumnings- eller emulgeringsmiddel paa sojaproteinbasis |
US4767704A (en) * | 1983-10-07 | 1988-08-30 | Columbia University In The City Of New York | Protein-free culture medium |
NZ210501A (en) | 1983-12-13 | 1991-08-27 | Kirin Amgen Inc | Erythropoietin produced by procaryotic or eucaryotic expression of an exogenous dna sequence |
FI86885C (fi) | 1984-04-20 | 1992-10-26 | Genentech Inc | Foerfarande foer framstaellning av human rekombinantfaktor viii och nukleinsyrasekvenser och vektorer anvaend daertill |
EP0217822B1 (en) | 1985-02-13 | 1993-05-12 | Scios Nova Inc. | Human metallothionein-ii promoter in mammalian expression system |
US4978616A (en) * | 1985-02-28 | 1990-12-18 | Verax Corporation | Fluidized cell cultivation process |
ZA862768B (en) | 1985-04-17 | 1986-12-30 | Zymogenetics Inc | Expression of factor vii and ix activities in mammalian cells |
GB8608020D0 (en) | 1986-04-02 | 1986-05-08 | Beecham Group Plc | Compounds |
EP0318487B1 (en) | 1986-08-04 | 1993-10-13 | The University Of New South Wales | Serum free tissue culture medium containing polymeric cell-protective agent |
AU627427B2 (en) | 1987-06-30 | 1992-08-27 | Amgen, Inc. | Production of kallikrein |
US5024947A (en) * | 1987-07-24 | 1991-06-18 | Cetus Corporation | Serum free media for the growth on insect cells and expression of products thereby |
JP2507882B2 (ja) | 1988-02-17 | 1996-06-19 | 工業技術院長 | 外部増殖因子非依存性増殖良好細胞株の製造法 |
US6048728A (en) * | 1988-09-23 | 2000-04-11 | Chiron Corporation | Cell culture medium for enhanced cell growth, culture longevity, and product expression |
JP2815613B2 (ja) | 1989-03-24 | 1998-10-27 | 株式会社リコー | 静電荷像現像用トナー |
US5573937A (en) | 1989-12-07 | 1996-11-12 | Snow Brand Milk Products Co., Ltd. | Serum free culture medium |
SE465222C5 (sv) | 1989-12-15 | 1998-02-10 | Pharmacia & Upjohn Ab | Ett rekombinant, humant faktor VIII-derivat och förfarande för dess framställning |
AT393356B (de) | 1989-12-22 | 1991-10-10 | Immuno Ag | Verfahren zur herstellung von fsme-virus-antigen |
WO1991010726A1 (en) * | 1990-01-22 | 1991-07-25 | The United States Of America, Represented By The Secretary, United States Department Of Commerce | Co-independent growth medium for maintenance and propagation of cells |
JP2844484B2 (ja) * | 1990-02-22 | 1999-01-06 | 味の素株式会社 | 組換え蛋白質の生産方法 |
JP2859679B2 (ja) | 1990-03-01 | 1999-02-17 | 協和醗酵工業株式会社 | 新規細胞株 |
JP2696001B2 (ja) | 1991-04-15 | 1998-01-14 | 財団法人化学及血清療法研究所 | 組換え蛋白質産生用培地 |
US5378612A (en) | 1990-05-11 | 1995-01-03 | Juridical Foundation The Chemo-Sero-Therapeutic Research Institute | Culture medium for production of recombinant protein |
US5122469A (en) * | 1990-10-03 | 1992-06-16 | Genentech, Inc. | Method for culturing Chinese hamster ovary cells to improve production of recombinant proteins |
GB9022545D0 (en) | 1990-10-17 | 1990-11-28 | Wellcome Found | Culture medium |
JPH04228066A (ja) | 1990-10-23 | 1992-08-18 | Rikagaku Kenkyusho | 外来遺伝子発現用培養細胞 |
EP0531562A1 (de) * | 1991-09-11 | 1993-03-17 | Doerr, Hans-Wilhelm, Prof. Dr. med. | Kultivierung von Säugetierzellen |
JPH05123178A (ja) * | 1991-11-01 | 1993-05-21 | Ajinomoto Co Inc | L−フエニルアラニンの製造法 |
DK53792D0 (da) | 1992-04-24 | 1992-04-24 | Novo Nordisk As | Fremgangsmaade til fremstilling af proteiner |
RU2057176C1 (ru) | 1992-05-20 | 1996-03-27 | Институт генетики АН Республики Молдова | Питательная среда для культивирования клеток человека и животных |
DE4313620A1 (de) | 1993-04-26 | 1994-10-27 | Biotechnolog Forschung Gmbh | Hamsterzellinien und Verfahren zur Glykoproteingewinnung |
AU7895898A (en) | 1993-04-26 | 1998-10-08 | Hans Wolf | Mammal cell lines and method of obtaining glycoproteins |
US5405637A (en) | 1993-06-30 | 1995-04-11 | Bristol-Myers Squibb Company | Milk protein partial hydrolysate and infant formula containing same |
JP2766165B2 (ja) * | 1993-08-02 | 1998-06-18 | 株式会社バイオポリマー・リサーチ | バクテリアセルロースの製造方法 |
CN1088984A (zh) * | 1993-11-11 | 1994-07-06 | 江西省医学科学研究所 | 一种用于造血祖细胞培养的无血清培养基 |
US5719050A (en) | 1993-12-24 | 1998-02-17 | Eiken Chemical Co., Ltd. | Animal cell culturing media containing N-acetyl-L-glutamic acid |
EP0666312A1 (en) | 1994-02-08 | 1995-08-09 | Wolfgang A. Renner | Process for the improvement of mammalian cell growth |
US5789247A (en) | 1994-04-01 | 1998-08-04 | Ballay; Annick | Expression in non-tumoral human lymphoblastoid lines with an integrative vector |
JP2684521B2 (ja) | 1994-08-19 | 1997-12-03 | ハムス株式会社 | ベルトループ縫付けミシンにおけるテープ折り曲げ端の形成維持方法及びその装置 |
WO1996007730A2 (de) | 1994-09-09 | 1996-03-14 | Renner Wolfgang A | Chemisches verfahren zur förderung der proliferation von tierischen zellen |
ATE542891T1 (de) | 1994-11-10 | 2012-02-15 | Baxter Healthcare Sa | Verfahren zur herstellung von biologischen produkten in protein-freier kultur |
AT403167B (de) | 1994-11-14 | 1997-11-25 | Immuno Ag | Selektion und expression von fremdproteinen mittels eines selektions-amplifikations-systems |
JP3244391B2 (ja) | 1994-12-08 | 2002-01-07 | 財団法人国際超電導産業技術研究センター | 複合基板及びそれを用いた単結晶基板の製造方法 |
EP0799310A1 (en) | 1994-12-16 | 1997-10-08 | Novartis AG | Production of recombinant secretory component |
JP3649249B2 (ja) * | 1995-02-23 | 2005-05-18 | クエスト・インターナショナル・サービシーズ・ビー・ブイ | 組織および細胞培養用ペプチド |
US5741705A (en) | 1995-02-23 | 1998-04-21 | Quest International Flavors & Food Ingredients Company, Division Of Indopco, Inc. | Method for in vitro cell growth of eucaryotic cells using low molecular weight peptides |
WO1996040866A1 (en) | 1995-06-07 | 1996-12-19 | Novartis Ag | Serum-free media for primitive hematopoietic cells and methods of use thereof |
AUPN442295A0 (en) | 1995-07-26 | 1995-08-17 | Commonwealth Scientific And Industrial Research Organisation | Regulated autocrine growth of mammalian cells |
JPH09107955A (ja) * | 1995-10-24 | 1997-04-28 | Kyowa Hakko Kogyo Co Ltd | 動物細胞培養用培地 |
ATE222064T1 (de) * | 1996-04-09 | 2002-08-15 | Du Pont | Isoflavon angereichertes sojaeiweissprodukt und verfahren zur herstellung |
US5851800A (en) * | 1996-05-14 | 1998-12-22 | Pharmacia & Upjohn Ab | Process for producing a protein |
JP2000517188A (ja) * | 1996-08-30 | 2000-12-26 | ライフ テクノロジーズ,インコーポレイテッド | 無血清哺乳動物細胞培養培地およびその使用 |
DE69738806D1 (de) * | 1996-10-10 | 2008-08-14 | Invitrogen Corp | Tierzellkulturmedium mit pflanzlichen nährstoffen |
JPH10211488A (ja) | 1997-01-28 | 1998-08-11 | Akai Electric Co Ltd | 紫外線殺菌装置 |
US6383810B2 (en) * | 1997-02-14 | 2002-05-07 | Invitrogen Corporation | Dry powder cells and cell culture reagents and methods of production thereof |
US5804420A (en) | 1997-04-18 | 1998-09-08 | Bayer Corporation | Preparation of recombinant Factor VIII in a protein free medium |
PT1849860E (pt) | 1997-05-28 | 2011-02-23 | Novartis Vaccines & Diagnostic | Processo de preparação de um factor imunogénico de corynebacterium diphtheriae utilizando um meio de cultura com extracto de levedura como fonte de aminoácidos e sem complexos proteicos de origem animal |
US6475725B1 (en) | 1997-06-20 | 2002-11-05 | Baxter Aktiengesellschaft | Recombinant cell clones having increased stability and methods of making and using the same |
AT407255B (de) * | 1997-06-20 | 2001-02-26 | Immuno Ag | Rekombinanter zellklon mit erhöhter stabilität in serum- und proteinfreiem medium und verfahren zur gewinnung des stabilen zellklons |
DK0986644T3 (da) | 1997-07-23 | 2007-01-29 | Roche Diagnostics Gmbh | Fremstilling af erythropoietin ved endogen genaktivering med virale promotorer |
JPH11211488A (ja) | 1998-01-21 | 1999-08-06 | Matsushita Electric Ind Co Ltd | 携帯情報端末を用いたデータ転送システム |
FR2775983B1 (fr) * | 1998-03-13 | 2000-11-10 | Pasteur Merieux Serums Vacc | Milieu et procede de propagation et de multiplication virales |
WO1999057246A1 (en) | 1998-05-01 | 1999-11-11 | Life Technologies, Inc. | Animal cell culture media comprising non-animal or plant-derived nutrients |
US6406909B1 (en) * | 1998-07-10 | 2002-06-18 | Chugai Seiyaku Kabushiki Kaisha | Serum-free medium for culturing animal cells |
AT409379B (de) * | 1999-06-02 | 2002-07-25 | Baxter Ag | Medium zur protein- und serumfreien kultivierung von zellen |
DK1200561T3 (da) | 1999-08-05 | 2006-10-16 | Baxter Ag | Rekombinant stabil celleklon, dens fremstilling og anvendelse |
PT1210411E (pt) | 1999-08-25 | 2006-12-29 | Immunex Corp | Composições e métodos para cultura celular melhorada |
WO2002024876A2 (en) | 2000-09-25 | 2002-03-28 | Polymun Scientific Immunbiologische Forschung Gmbh | Live influenza vaccine and method of manufacture |
EP1208966A1 (en) | 2000-11-27 | 2002-05-29 | Cheng-Kun Liao | Manufacturing process of patio tabletop glass with broken protection |
EP1520008B1 (en) | 2002-07-09 | 2012-09-05 | Baxter International Inc. | Animal protein free media for cultivation of cells |
JP4316484B2 (ja) | 2004-12-10 | 2009-08-19 | シャープ株式会社 | 画像形成装置、トナー濃度制御方法、トナー濃度制御プログラムおよびその記録媒体 |
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