ES2099678A1 - Procedimiento para la inactivacion de virus en proteinas. - Google Patents
Procedimiento para la inactivacion de virus en proteinas.Info
- Publication number
- ES2099678A1 ES2099678A1 ES09502143A ES9502143A ES2099678A1 ES 2099678 A1 ES2099678 A1 ES 2099678A1 ES 09502143 A ES09502143 A ES 09502143A ES 9502143 A ES9502143 A ES 9502143A ES 2099678 A1 ES2099678 A1 ES 2099678A1
- Authority
- ES
- Spain
- Prior art keywords
- proteins
- inactivating viruses
- denaturing
- incubation
- extreme
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 241000700605 Viruses Species 0.000 title abstract 2
- 230000000415 inactivating effect Effects 0.000 title abstract 2
- 102000004169 proteins and genes Human genes 0.000 title abstract 2
- 108090000623 proteins and genes Proteins 0.000 title abstract 2
- 230000004071 biological effect Effects 0.000 abstract 1
- 238000011534 incubation Methods 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 210000004779 membrane envelope Anatomy 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
- A61L2/0005—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
- A61L2/0082—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using chemical substances
- A61L2/0088—Liquid substances
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
Abstract
PROCEDIMIENTO PARA LA INACTIVACION DE VIRUS EN PROTEINAS. SE DESCRIBE UN PROCEDIMIENTO INDUSTRIAL PARA INACTIVAR VIRUS EN GENERAL (CON Y SIN CUBIERTA LIPIDICA) DE FORMA EFICIENTE, EN MEDIOS QUE CONTIENEN PROTEINAS PARA USO TERAPEUTICO, SIN QUE SE PRODUZCA DESNATURALIZACION NI PERDIDA RELEVANTE DE ACTIVIDAD BIOLOGICA, MEDIANTE INCUBACION A PH EXTREMO (ALCALI) EN UN MEDIO ESTABILIZADO.
Priority Applications (13)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES09502143A ES2099678B1 (es) | 1995-11-03 | 1995-11-03 | Procedimiento para la inactivacion de virus en proteinas. |
EP96500137A EP0771567B1 (en) | 1995-11-03 | 1996-10-18 | A method of inactivating viruses in proteins |
AT96500137T ATE211928T1 (de) | 1995-11-03 | 1996-10-18 | Verfahren zur inaktivierung von viren in proteinen |
DE69618536T DE69618536T2 (de) | 1995-11-03 | 1996-10-18 | Verfahren zur Inaktivierung von Viren in Proteinen |
ES96500137T ES2170845T3 (es) | 1995-11-03 | 1996-10-18 | Procedimiento para la inactivacion de virus en proteinas. |
HU9602914A HU221239B1 (en) | 1995-11-03 | 1996-10-21 | Method of inactivating viruses in proteins |
ARP960104859A AR004224A1 (es) | 1995-11-03 | 1996-10-23 | Procedimiento para la inactivacion de virus en soluciones de proteinas |
UY24358A UY24358A1 (es) | 1995-11-03 | 1996-10-29 | Procedimiento para la inactivacion de virus en proteinas |
MX9605278A MX9605278A (es) | 1995-11-03 | 1996-10-31 | Procedimiento para la inactivacion de virus en proteinas. |
SK1407-96A SK281404B6 (sk) | 1995-11-03 | 1996-10-31 | Spôsob inaktivácie vírusov v proteínoch |
CZ19963215A CZ292651B6 (cs) | 1995-11-03 | 1996-11-01 | Způsob inaktivace virů v proteinech |
US08/742,502 US5932468A (en) | 1995-11-03 | 1996-11-01 | Method of inactivating viruses in proteins |
JP8292614A JP3024073B2 (ja) | 1995-11-03 | 1996-11-05 | タンパク質中のウイルスを不活性化する方法 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES09502143A ES2099678B1 (es) | 1995-11-03 | 1995-11-03 | Procedimiento para la inactivacion de virus en proteinas. |
Publications (2)
Publication Number | Publication Date |
---|---|
ES2099678A1 true ES2099678A1 (es) | 1997-05-16 |
ES2099678B1 ES2099678B1 (es) | 1998-02-16 |
Family
ID=8292048
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES09502143A Expired - Fee Related ES2099678B1 (es) | 1995-11-03 | 1995-11-03 | Procedimiento para la inactivacion de virus en proteinas. |
ES96500137T Expired - Lifetime ES2170845T3 (es) | 1995-11-03 | 1996-10-18 | Procedimiento para la inactivacion de virus en proteinas. |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES96500137T Expired - Lifetime ES2170845T3 (es) | 1995-11-03 | 1996-10-18 | Procedimiento para la inactivacion de virus en proteinas. |
Country Status (12)
Country | Link |
---|---|
US (1) | US5932468A (es) |
EP (1) | EP0771567B1 (es) |
JP (1) | JP3024073B2 (es) |
AR (1) | AR004224A1 (es) |
AT (1) | ATE211928T1 (es) |
CZ (1) | CZ292651B6 (es) |
DE (1) | DE69618536T2 (es) |
ES (2) | ES2099678B1 (es) |
HU (1) | HU221239B1 (es) |
MX (1) | MX9605278A (es) |
SK (1) | SK281404B6 (es) |
UY (1) | UY24358A1 (es) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9900428D0 (en) * | 1999-01-08 | 1999-02-24 | Nat Blood Authority | Virus inactivation process |
CZ300547B6 (cs) | 1999-02-22 | 2009-06-10 | University Of Connecticut | Nové formulace faktoru VIII prosté albuminu |
US20090017069A1 (en) | 2000-06-29 | 2009-01-15 | Lipid Sciences, Inc. | SARS Vaccine Compositions and Methods of Making and Using Them |
CN100457896C (zh) * | 2005-10-26 | 2009-02-04 | 李法卿 | 灭活生物制品中病毒和去除细菌内毒素的方法 |
WO2010054238A1 (en) | 2008-11-07 | 2010-05-14 | Baxter International Inc. | Factor viii formulations |
LT3436593T (lt) * | 2016-03-28 | 2023-03-10 | Ultragenyx Pharmaceutical Inc. | Adenoviruso šiluminio inaktyvavimo būdai |
KR101938304B1 (ko) | 2016-05-13 | 2019-04-10 | 연세대학교 산학협력단 | 비대칭형 커프 구조를 갖는 구강 또는 비강 기관 삽관 튜브 |
WO2018119561A1 (zh) * | 2016-12-26 | 2018-07-05 | 通博国际有限公司 | 可塌陷鼻腔喷射导管 |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1994003590A1 (fr) * | 1992-08-06 | 1994-02-17 | Association Pour L'essor De La Transfusion Sanguine Dans La Region Du Nord | Procede d'inactivation virale des produits plasmatiques par des fluides supercritiques ou subcritiques |
WO1994026287A1 (en) * | 1993-05-07 | 1994-11-24 | Pharmacia Ab | Purification of plasma proteins |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3941696A (en) * | 1973-12-20 | 1976-03-02 | Baylor College Of Medicine | Sterilization of holding tanks and toilet bowls by quaternary compounds |
US4055655A (en) * | 1975-07-21 | 1977-10-25 | National Research Laboratories | Complexes of heavy metal ions and polyfunctional organic ligands used as antimicrobial agents |
JPS53142593A (en) * | 1977-12-12 | 1978-12-12 | Green Cross Corp:The | Stabilization of urokinase by heating |
JPH0669961B2 (ja) * | 1984-09-25 | 1994-09-07 | 株式会社ミドリ十字 | 免疫グロブリンの加熱処理方法 |
JPH07121877B2 (ja) * | 1986-05-31 | 1995-12-25 | 株式会社ミドリ十字 | 静注用非化学修飾免疫グロブリンの加熱処理方法 |
DE3816139A1 (de) * | 1987-10-17 | 1989-04-27 | Bayer Ag | Verfahren zur herstellung von paramunitaetsinducern |
ATE85220T1 (de) * | 1988-05-27 | 1993-02-15 | Centre Regional De Transfusion | Verfahren zur herstellung eines hochreinen, virusfreien antihaemophiliefaktors mittels chromatographie. |
GB9306806D0 (en) * | 1993-04-01 | 1993-05-26 | Unilever Plc | Disinfectant compositions |
-
1995
- 1995-11-03 ES ES09502143A patent/ES2099678B1/es not_active Expired - Fee Related
-
1996
- 1996-10-18 ES ES96500137T patent/ES2170845T3/es not_active Expired - Lifetime
- 1996-10-18 EP EP96500137A patent/EP0771567B1/en not_active Expired - Lifetime
- 1996-10-18 AT AT96500137T patent/ATE211928T1/de active
- 1996-10-18 DE DE69618536T patent/DE69618536T2/de not_active Expired - Lifetime
- 1996-10-21 HU HU9602914A patent/HU221239B1/hu unknown
- 1996-10-23 AR ARP960104859A patent/AR004224A1/es active IP Right Grant
- 1996-10-29 UY UY24358A patent/UY24358A1/es not_active IP Right Cessation
- 1996-10-31 SK SK1407-96A patent/SK281404B6/sk not_active IP Right Cessation
- 1996-10-31 MX MX9605278A patent/MX9605278A/es unknown
- 1996-11-01 CZ CZ19963215A patent/CZ292651B6/cs unknown
- 1996-11-01 US US08/742,502 patent/US5932468A/en not_active Expired - Lifetime
- 1996-11-05 JP JP8292614A patent/JP3024073B2/ja not_active Expired - Lifetime
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1994003590A1 (fr) * | 1992-08-06 | 1994-02-17 | Association Pour L'essor De La Transfusion Sanguine Dans La Region Du Nord | Procede d'inactivation virale des produits plasmatiques par des fluides supercritiques ou subcritiques |
WO1994026287A1 (en) * | 1993-05-07 | 1994-11-24 | Pharmacia Ab | Purification of plasma proteins |
Also Published As
Publication number | Publication date |
---|---|
ES2170845T3 (es) | 2002-08-16 |
DE69618536T2 (de) | 2002-09-12 |
HUP9602914A2 (en) | 1997-08-28 |
JPH09187273A (ja) | 1997-07-22 |
MX9605278A (es) | 1997-05-31 |
HU9602914D0 (en) | 1996-12-30 |
HU221239B1 (en) | 2002-08-28 |
ATE211928T1 (de) | 2002-02-15 |
CZ292651B6 (cs) | 2003-11-12 |
CZ321596A3 (en) | 1997-05-14 |
SK281404B6 (sk) | 2001-03-12 |
DE69618536D1 (de) | 2002-02-21 |
SK140796A3 (en) | 1997-07-09 |
UY24358A1 (es) | 1996-11-13 |
HUP9602914A3 (en) | 2000-03-28 |
US5932468A (en) | 1999-08-03 |
AR004224A1 (es) | 1998-11-04 |
EP0771567A1 (en) | 1997-05-07 |
JP3024073B2 (ja) | 2000-03-21 |
EP0771567B1 (en) | 2002-01-16 |
ES2099678B1 (es) | 1998-02-16 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
EC2A | Search report published |
Date of ref document: 19970516 Kind code of ref document: A1 Effective date: 19970516 |
|
PC2A | Transfer of patent | ||
FD1A | Patent lapsed |
Effective date: 20071105 |