ES2099678A1 - Procedimiento para la inactivacion de virus en proteinas. - Google Patents

Procedimiento para la inactivacion de virus en proteinas.

Info

Publication number
ES2099678A1
ES2099678A1 ES09502143A ES9502143A ES2099678A1 ES 2099678 A1 ES2099678 A1 ES 2099678A1 ES 09502143 A ES09502143 A ES 09502143A ES 9502143 A ES9502143 A ES 9502143A ES 2099678 A1 ES2099678 A1 ES 2099678A1
Authority
ES
Spain
Prior art keywords
proteins
inactivating viruses
denaturing
incubation
extreme
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES09502143A
Other languages
English (en)
Other versions
ES2099678B1 (es
Inventor
Debart Pere Ristol
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Grifols SA
Original Assignee
Grifols SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Grifols SA filed Critical Grifols SA
Priority to ES09502143A priority Critical patent/ES2099678B1/es
Priority to EP96500137A priority patent/EP0771567B1/en
Priority to AT96500137T priority patent/ATE211928T1/de
Priority to DE69618536T priority patent/DE69618536T2/de
Priority to ES96500137T priority patent/ES2170845T3/es
Priority to HU9602914A priority patent/HU221239B1/hu
Priority to ARP960104859A priority patent/AR004224A1/es
Priority to UY24358A priority patent/UY24358A1/es
Priority to MX9605278A priority patent/MX9605278A/es
Priority to SK1407-96A priority patent/SK281404B6/sk
Priority to CZ19963215A priority patent/CZ292651B6/cs
Priority to US08/742,502 priority patent/US5932468A/en
Priority to JP8292614A priority patent/JP3024073B2/ja
Publication of ES2099678A1 publication Critical patent/ES2099678A1/es
Application granted granted Critical
Publication of ES2099678B1 publication Critical patent/ES2099678B1/es
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/0005—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
    • A61L2/0082—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using chemical substances
    • A61L2/0088—Liquid substances

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)

Abstract

PROCEDIMIENTO PARA LA INACTIVACION DE VIRUS EN PROTEINAS. SE DESCRIBE UN PROCEDIMIENTO INDUSTRIAL PARA INACTIVAR VIRUS EN GENERAL (CON Y SIN CUBIERTA LIPIDICA) DE FORMA EFICIENTE, EN MEDIOS QUE CONTIENEN PROTEINAS PARA USO TERAPEUTICO, SIN QUE SE PRODUZCA DESNATURALIZACION NI PERDIDA RELEVANTE DE ACTIVIDAD BIOLOGICA, MEDIANTE INCUBACION A PH EXTREMO (ALCALI) EN UN MEDIO ESTABILIZADO.
ES09502143A 1995-11-03 1995-11-03 Procedimiento para la inactivacion de virus en proteinas. Expired - Fee Related ES2099678B1 (es)

Priority Applications (13)

Application Number Priority Date Filing Date Title
ES09502143A ES2099678B1 (es) 1995-11-03 1995-11-03 Procedimiento para la inactivacion de virus en proteinas.
EP96500137A EP0771567B1 (en) 1995-11-03 1996-10-18 A method of inactivating viruses in proteins
AT96500137T ATE211928T1 (de) 1995-11-03 1996-10-18 Verfahren zur inaktivierung von viren in proteinen
DE69618536T DE69618536T2 (de) 1995-11-03 1996-10-18 Verfahren zur Inaktivierung von Viren in Proteinen
ES96500137T ES2170845T3 (es) 1995-11-03 1996-10-18 Procedimiento para la inactivacion de virus en proteinas.
HU9602914A HU221239B1 (en) 1995-11-03 1996-10-21 Method of inactivating viruses in proteins
ARP960104859A AR004224A1 (es) 1995-11-03 1996-10-23 Procedimiento para la inactivacion de virus en soluciones de proteinas
UY24358A UY24358A1 (es) 1995-11-03 1996-10-29 Procedimiento para la inactivacion de virus en proteinas
MX9605278A MX9605278A (es) 1995-11-03 1996-10-31 Procedimiento para la inactivacion de virus en proteinas.
SK1407-96A SK281404B6 (sk) 1995-11-03 1996-10-31 Spôsob inaktivácie vírusov v proteínoch
CZ19963215A CZ292651B6 (cs) 1995-11-03 1996-11-01 Způsob inaktivace virů v proteinech
US08/742,502 US5932468A (en) 1995-11-03 1996-11-01 Method of inactivating viruses in proteins
JP8292614A JP3024073B2 (ja) 1995-11-03 1996-11-05 タンパク質中のウイルスを不活性化する方法

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES09502143A ES2099678B1 (es) 1995-11-03 1995-11-03 Procedimiento para la inactivacion de virus en proteinas.

Publications (2)

Publication Number Publication Date
ES2099678A1 true ES2099678A1 (es) 1997-05-16
ES2099678B1 ES2099678B1 (es) 1998-02-16

Family

ID=8292048

Family Applications (2)

Application Number Title Priority Date Filing Date
ES09502143A Expired - Fee Related ES2099678B1 (es) 1995-11-03 1995-11-03 Procedimiento para la inactivacion de virus en proteinas.
ES96500137T Expired - Lifetime ES2170845T3 (es) 1995-11-03 1996-10-18 Procedimiento para la inactivacion de virus en proteinas.

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES96500137T Expired - Lifetime ES2170845T3 (es) 1995-11-03 1996-10-18 Procedimiento para la inactivacion de virus en proteinas.

Country Status (12)

Country Link
US (1) US5932468A (es)
EP (1) EP0771567B1 (es)
JP (1) JP3024073B2 (es)
AR (1) AR004224A1 (es)
AT (1) ATE211928T1 (es)
CZ (1) CZ292651B6 (es)
DE (1) DE69618536T2 (es)
ES (2) ES2099678B1 (es)
HU (1) HU221239B1 (es)
MX (1) MX9605278A (es)
SK (1) SK281404B6 (es)
UY (1) UY24358A1 (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9900428D0 (en) * 1999-01-08 1999-02-24 Nat Blood Authority Virus inactivation process
CZ300547B6 (cs) 1999-02-22 2009-06-10 University Of Connecticut Nové formulace faktoru VIII prosté albuminu
US20090017069A1 (en) 2000-06-29 2009-01-15 Lipid Sciences, Inc. SARS Vaccine Compositions and Methods of Making and Using Them
CN100457896C (zh) * 2005-10-26 2009-02-04 李法卿 灭活生物制品中病毒和去除细菌内毒素的方法
WO2010054238A1 (en) 2008-11-07 2010-05-14 Baxter International Inc. Factor viii formulations
LT3436593T (lt) * 2016-03-28 2023-03-10 Ultragenyx Pharmaceutical Inc. Adenoviruso šiluminio inaktyvavimo būdai
KR101938304B1 (ko) 2016-05-13 2019-04-10 연세대학교 산학협력단 비대칭형 커프 구조를 갖는 구강 또는 비강 기관 삽관 튜브
WO2018119561A1 (zh) * 2016-12-26 2018-07-05 通博国际有限公司 可塌陷鼻腔喷射导管

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994003590A1 (fr) * 1992-08-06 1994-02-17 Association Pour L'essor De La Transfusion Sanguine Dans La Region Du Nord Procede d'inactivation virale des produits plasmatiques par des fluides supercritiques ou subcritiques
WO1994026287A1 (en) * 1993-05-07 1994-11-24 Pharmacia Ab Purification of plasma proteins

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3941696A (en) * 1973-12-20 1976-03-02 Baylor College Of Medicine Sterilization of holding tanks and toilet bowls by quaternary compounds
US4055655A (en) * 1975-07-21 1977-10-25 National Research Laboratories Complexes of heavy metal ions and polyfunctional organic ligands used as antimicrobial agents
JPS53142593A (en) * 1977-12-12 1978-12-12 Green Cross Corp:The Stabilization of urokinase by heating
JPH0669961B2 (ja) * 1984-09-25 1994-09-07 株式会社ミドリ十字 免疫グロブリンの加熱処理方法
JPH07121877B2 (ja) * 1986-05-31 1995-12-25 株式会社ミドリ十字 静注用非化学修飾免疫グロブリンの加熱処理方法
DE3816139A1 (de) * 1987-10-17 1989-04-27 Bayer Ag Verfahren zur herstellung von paramunitaetsinducern
ATE85220T1 (de) * 1988-05-27 1993-02-15 Centre Regional De Transfusion Verfahren zur herstellung eines hochreinen, virusfreien antihaemophiliefaktors mittels chromatographie.
GB9306806D0 (en) * 1993-04-01 1993-05-26 Unilever Plc Disinfectant compositions

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994003590A1 (fr) * 1992-08-06 1994-02-17 Association Pour L'essor De La Transfusion Sanguine Dans La Region Du Nord Procede d'inactivation virale des produits plasmatiques par des fluides supercritiques ou subcritiques
WO1994026287A1 (en) * 1993-05-07 1994-11-24 Pharmacia Ab Purification of plasma proteins

Also Published As

Publication number Publication date
ES2170845T3 (es) 2002-08-16
DE69618536T2 (de) 2002-09-12
HUP9602914A2 (en) 1997-08-28
JPH09187273A (ja) 1997-07-22
MX9605278A (es) 1997-05-31
HU9602914D0 (en) 1996-12-30
HU221239B1 (en) 2002-08-28
ATE211928T1 (de) 2002-02-15
CZ292651B6 (cs) 2003-11-12
CZ321596A3 (en) 1997-05-14
SK281404B6 (sk) 2001-03-12
DE69618536D1 (de) 2002-02-21
SK140796A3 (en) 1997-07-09
UY24358A1 (es) 1996-11-13
HUP9602914A3 (en) 2000-03-28
US5932468A (en) 1999-08-03
AR004224A1 (es) 1998-11-04
EP0771567A1 (en) 1997-05-07
JP3024073B2 (ja) 2000-03-21
EP0771567B1 (en) 2002-01-16
ES2099678B1 (es) 1998-02-16

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