MX9800719A - Proteinas de transporte y sus usos. - Google Patents

Proteinas de transporte y sus usos.

Info

Publication number
MX9800719A
MX9800719A MX9800719A MX9800719A MX9800719A MX 9800719 A MX9800719 A MX 9800719A MX 9800719 A MX9800719 A MX 9800719A MX 9800719 A MX9800719 A MX 9800719A MX 9800719 A MX9800719 A MX 9800719A
Authority
MX
Mexico
Prior art keywords
transport proteins
proteins
cells
methods
transport
Prior art date
Application number
MX9800719A
Other languages
English (en)
Inventor
Peter Francis Joseph O'hare
Gillian Daphne Elliott
Original Assignee
Marie Curie Cancer Care
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9515568.5A external-priority patent/GB9515568D0/en
Priority claimed from GBGB9601570.6A external-priority patent/GB9601570D0/en
Application filed by Marie Curie Cancer Care filed Critical Marie Curie Cancer Care
Publication of MX9800719A publication Critical patent/MX9800719A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/10—Fusion polypeptide containing a localisation/targetting motif containing a tag for extracellular membrane crossing, e.g. TAT or VP22
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/16011—Herpesviridae
    • C12N2710/16611—Simplexvirus, e.g. human herpesvirus 1, 2
    • C12N2710/16622—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Abstract

La presente invencion se relaciona con proteínas de transporte, en particular VP22 y homologos de la misma, y con métodos para suministrar estas proteínas con cualquiera molécula asociada a una poblacion objetivo de células. Estas proteínas de transporte tienen aplicaciones en terapias de genes y métodos para dirigir agentes a células en las que se requiere objetivo de alta eficiencia.
MX9800719A 1995-07-28 1998-01-26 Proteinas de transporte y sus usos. MX9800719A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9515568.5A GB9515568D0 (en) 1995-07-28 1995-07-28 Transport proteins and their uses
GBGB9601570.6A GB9601570D0 (en) 1996-01-26 1996-01-26 Transport proteins and their uses

Publications (1)

Publication Number Publication Date
MX9800719A true MX9800719A (es) 1998-11-29

Family

ID=26307479

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9800719A MX9800719A (es) 1995-07-28 1998-01-26 Proteinas de transporte y sus usos.

Country Status (11)

Country Link
US (4) US6184038B1 (es)
EP (1) EP0845043B1 (es)
JP (1) JPH11510386A (es)
CN (1) CN1208438A (es)
AT (1) ATE365808T1 (es)
AU (1) AU705563B2 (es)
BR (1) BR9610058A (es)
CA (1) CA2227786A1 (es)
DE (1) DE69637147T2 (es)
MX (1) MX9800719A (es)
WO (1) WO1997005265A1 (es)

Families Citing this family (100)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0845043B1 (en) * 1995-07-28 2007-06-27 Marie Curie Cancer Care Transport proteins and their uses
US6017735A (en) * 1997-01-23 2000-01-25 Marie Curie Cancer Care Materials and methods for intracellular transport and their uses
GB9705903D0 (en) * 1997-03-21 1997-05-07 Elliott Gillian D VP22 Proteins and uses thereof
CA2291010A1 (en) 1997-06-02 1998-12-10 Chiron Corporation Herpes simplex virus vp22 vaccines and methods of use
DE69940805D1 (de) 1998-01-31 2009-06-10 Sinai School Medicine Verfahren und reagenzien zur verminderung der klinischen reaktion zur allergie
GB9816761D0 (en) 1998-07-31 1998-09-30 Phogen Limited Herpesvirus preparations and their uses
JP2002522451A (ja) 1998-08-07 2002-07-23 ユニバーシティ オブ ワシントン 免疫学的単純ヘルペスウイルス抗原とその使用法
DE19845420C2 (de) * 1998-10-02 2000-11-16 Deutsches Krebsforsch Interzelluläre Ausbreitung rekombinanter DNA
JP4854853B2 (ja) * 1998-11-12 2012-01-18 ライフ テクノロジーズ コーポレーション トランスフェクション薬剤
US6316252B1 (en) * 1998-12-17 2001-11-13 Wisconsin Alumni Research Foundation Biotherapeutic delivery system
CA2365625A1 (en) * 1999-03-10 2000-09-14 Phogen Limited Delivery of substances to cells
WO2000058488A2 (en) * 1999-03-31 2000-10-05 Invitrogen Corporation Delivery of functional protein sequences by translocating polypeptides
US6773920B1 (en) 1999-03-31 2004-08-10 Invitrogen Corporation Delivery of functional protein sequences by translocating polypeptides
WO2000061617A2 (en) * 1999-04-12 2000-10-19 Modex Therapeutiques, S.A. Transiently immortalized cells for use in gene therapy
US6451601B1 (en) 1999-04-12 2002-09-17 Modex Therapeutiques, S.A. Transiently immortalized cells for use in gene therapy
US6358739B1 (en) 1999-04-12 2002-03-19 Modex Therapeutiques, S.A. Transiently immortalized cells
DE19933089A1 (de) * 1999-07-15 2001-01-18 Max Delbrueck Centrum Mittel zur Gewerbsregeneration
EP1210362A2 (en) 1999-09-01 2002-06-05 University Of Pittsburgh Of The Commonwealth System Of Higher Education Identification of peptides that facilitate uptake and cytoplasmic and/or nuclear transport of proteins, dna and viruses
US20030219826A1 (en) * 1999-09-01 2003-11-27 Robbins Paul D. Identification of peptides that facilitate uptake and cytoplasmic and/or nuclear transport of proteins, DNA and viruses
US20030104622A1 (en) * 1999-09-01 2003-06-05 Robbins Paul D. Identification of peptides that facilitate uptake and cytoplasmic and/or nuclear transport of proteins, DNA and viruses
ATE345389T1 (de) 1999-09-30 2006-12-15 Univ Washington Immunologisch relevante antigene aus herpes simplexvirus
US20030108539A1 (en) 2000-02-14 2003-06-12 Christophe Bonny Cell-permeable peptide inhibitors of the JNK signal transduction pathway
US8183339B1 (en) 1999-10-12 2012-05-22 Xigen S.A. Cell-permeable peptide inhibitors of the JNK signal transduction pathway
US20040082509A1 (en) 1999-10-12 2004-04-29 Christophe Bonny Cell-permeable peptide inhibitors of the JNK signal transduction pathway
DE19955576B4 (de) * 1999-11-18 2008-02-28 Faustus Forschungs Cie. Translational Cancer Research Gmbh Transferverbindungen, ihre Herstellung und ihre Verwendung
GB9930519D0 (en) 1999-12-24 2000-02-16 Phogen Limited Uses of transport proteins
DE10001230A1 (de) * 2000-01-13 2001-08-02 Deutsches Krebsforsch Immunisierungsmittel
US6688084B2 (en) * 2000-03-24 2004-02-10 International Paper Company Automated bulk box strapper
US7318928B2 (en) * 2000-08-01 2008-01-15 The Johns Hopkins University Molecular vaccine linking intercellular spreading protein to an antigen
GB0022101D0 (en) * 2000-09-08 2000-10-25 Phogen Ltd Delivery of substances to cells
US6472176B2 (en) * 2000-12-14 2002-10-29 Genvec, Inc. Polynucleotide encoding chimeric protein and related vector, cell, and method of expression thereof
GB0112818D0 (en) * 2001-05-25 2001-07-18 Lorantis Ltd Conjugate
EP2191845A1 (en) 2001-07-31 2010-06-02 University of Washington Immunology significant herpes simplex virus antigens and methods for using same
WO2003042239A1 (en) * 2001-11-12 2003-05-22 Stichting Sanquin Bloedvoorziening Peptides inhibiting signaling by ras-like gtpases
CA2486449A1 (en) * 2002-05-17 2004-02-19 Automated Cell, Inc. Determination of protein function
WO2004009027A2 (en) * 2002-07-19 2004-01-29 Myriad Genetics, Inc Method and composition for treating and preventing herpesvirus infection
AU2003267124A1 (en) 2002-09-09 2004-03-29 Dana-Farber Cancer Institute, Inc. Bh3 peptides and method of use thereof
AU2004204456A1 (en) * 2003-01-09 2004-07-29 Invitrogen Corporation Cellular delivery and activation polypeptide-nucleic acid complexes
IL157787A (en) * 2003-09-07 2010-12-30 Mosaid Technologies Inc Modular outlet for data communications network
ITRM20030376A1 (it) 2003-07-31 2005-02-01 Univ Roma Procedimento per l'isolamento e l'espansione di cellule staminali cardiache da biopsia.
GB0321311D0 (en) * 2003-09-12 2003-10-15 Phogen Ltd Delivery of substances to cells
US11660317B2 (en) 2004-11-08 2023-05-30 The Johns Hopkins University Compositions comprising cardiosphere-derived cells for use in cell therapy
ATE483158T1 (de) 2005-04-05 2010-10-15 Allergan Inc Clostridientoxinaktivitätstests
US8080517B2 (en) 2005-09-12 2011-12-20 Xigen Sa Cell-permeable peptide inhibitors of the JNK signal transduction pathway
WO2007031098A1 (en) 2005-09-12 2007-03-22 Xigen S.A. Cell-permeable peptide inhibitors of the jnk signal transduction pathway
US20090227032A1 (en) * 2005-12-13 2009-09-10 Kyoto University Nuclear reprogramming factor and induced pluripotent stem cells
EP2208786B1 (en) 2005-12-13 2018-08-01 Kyoto University Nuclear reprogramming factor
US8278104B2 (en) 2005-12-13 2012-10-02 Kyoto University Induced pluripotent stem cells produced with Oct3/4, Klf4 and Sox2
US8129187B2 (en) 2005-12-13 2012-03-06 Kyoto University Somatic cell reprogramming by retroviral vectors encoding Oct3/4. Klf4, c-Myc and Sox2
CN101374860A (zh) 2005-12-23 2009-02-25 技术转让合伙人公司 用作神经递质分泌抑制剂和肌肉松弛诱导物的合成肽
JP2009532033A (ja) 2006-03-31 2009-09-10 ダナ ファーバー キャンサー インスティテュート，インコーポレイテッド 細胞の化学感受性を定量する方法
WO2008021484A2 (en) 2006-08-16 2008-02-21 Eutropics Pharmaceuticals Assay system to identify therapeutic agents
JP2008307007A (ja) * 2007-06-15 2008-12-25 Bayer Schering Pharma Ag 出生後のヒト組織由来未分化幹細胞から誘導したヒト多能性幹細胞
US9213999B2 (en) 2007-06-15 2015-12-15 Kyoto University Providing iPSCs to a customer
GB0724253D0 (en) * 2007-12-12 2008-01-30 Fermentas Uab Transfection reagent
ES2722198T3 (es) * 2008-05-02 2019-08-08 Univ Kyoto Método de reprogramación nuclear
WO2009143864A1 (en) 2008-05-30 2009-12-03 Xigen S.A. Use of cell-permeable peptide inhibitors of the jnk signal transduction pathway for the treatment of chronic or non-chronic inflammatory digestive diseases
WO2009143865A1 (en) 2008-05-30 2009-12-03 Xigen S.A. Use of cell-permeable peptide inhibitors of the jnk signal transduction pathway for the treatment of various diseases
WO2010072228A1 (en) 2008-12-22 2010-07-01 Xigen S.A. Novel transporter constructs and transporter cargo conjugate molecules
US8460674B2 (en) 2009-02-07 2013-06-11 University Of Washington HSV-1 epitopes and methods for using same
EP2413950A4 (en) 2009-04-03 2013-05-01 Univ Washington ANTIGENIC HSV-2 PEPTIDE AND METHOD OF USE THEREOF
GB0917792D0 (en) * 2009-10-12 2009-11-25 Fermentas Uab Delivery agent
US9856456B2 (en) 2009-10-12 2018-01-02 Thermo Fisher Scientific Baltics Uab Delivery agent
DK2547771T3 (da) * 2010-03-18 2017-01-16 Spiber Tech Ab Fremstilling af proteiner og polypeptider
US9845457B2 (en) 2010-04-30 2017-12-19 Cedars-Sinai Medical Center Maintenance of genomic stability in cultured stem cells
WO2011160653A1 (en) 2010-06-21 2011-12-29 Xigen S.A. Novel jnk inhibitor molecules
WO2012006440A2 (en) 2010-07-07 2012-01-12 Cellular Dynamics International, Inc. Endothelial cell production by programming
PL2902035T3 (pl) 2010-10-14 2019-04-30 Xigen Inflammation Ltd Przechodzące przez komórkę peptydowe inhibitory szlaku przekazywania sygnałów przez JNK do zastosowania w leczeniu chorób zapalnych oka
JP5857056B2 (ja) 2010-10-14 2016-02-10 ザイジェン インフラメーション エルティーディー 慢性又は非慢性の炎症性眼疾患を治療するためのｊｎｋシグナル伝達経路の細胞透過性ペプチド阻害剤の使用
US9127283B2 (en) 2010-11-24 2015-09-08 Clontech Laboratories, Inc. Inducible expression system transcription modulators comprising a distributed protein transduction domain and methods for using the same
EP2673358B1 (en) 2011-02-08 2019-01-09 FUJIFILM Cellular Dynamics, Inc. Hematopoietic precursor cell production by programming
BR112014013041A2 (pt) 2011-11-30 2019-09-24 Xigen Inflammation Ltd uso de inibidores de peptídeos de permeação celular do curso de transdução de sinal de jnk para o tratamento da síndrome do olho seco
WO2013091670A1 (en) 2011-12-21 2013-06-27 Xigen S.A. Novel jnk inhibitor molecules for treatment of various diseases
WO2013184527A1 (en) 2012-06-05 2013-12-12 Capricor, Inc. Optimized methods for generation of cardiac stem cells from cardiac tissue and their use in cardiac therapy
JP6433896B2 (ja) 2012-08-13 2018-12-05 シーダーズ−サイナイ・メディカル・センターＣｅｄａｒｓ−Ｓｉｎａｉ Ｍｅｄｉｃａｌ Ｃｅｎｔｅｒ 組織再生のためのエキソソームおよびマイクロリボ核酸
CA2885230C (en) 2012-09-19 2021-08-03 Anthony Letai Dynamic bh3 profiling
WO2014206427A1 (en) 2013-06-26 2014-12-31 Xigen Inflammation Ltd. New use of cell-permeable peptide inhibitors of the jnk signal transduction pathway for the treatment of various diseases
WO2015197098A1 (en) 2014-06-26 2015-12-30 Xigen Inflammation Ltd. New use of cell-permeable peptide inhibitors of the jnk signal transduction pathway for the treatment of various diseases
WO2014206426A1 (en) 2013-06-26 2014-12-31 Xigen Inflammation Ltd. New use for jnk inhibitor molecules for treatment of various diseases
WO2015197097A1 (en) 2014-06-26 2015-12-30 Xigen Inflammation Ltd. New use for jnk inhibitor molecules for treatment of various diseases
WO2016055160A2 (en) 2014-10-08 2016-04-14 Xigen Inflammation Ltd. New use of cell-permeable peptide inhibitors of the jnk signal transduction pathway for the treatment of various diseases
US10624948B2 (en) 2013-06-26 2020-04-21 Xigen Inflammation Ltd. Use of cell-permeable peptide inhibitors of the JNK signal transduction pathway for the treatment of various diseases
WO2015042249A1 (en) 2013-09-19 2015-03-26 Dana-Farber Cancer Institute, Inc. Methods of bh3 profiling
EP3169310A1 (en) 2014-07-15 2017-05-24 Life Technologies Corporation Compositions with lipid aggregates and methods for efficient delivery of molecules to cells
AU2015327812B2 (en) 2014-10-03 2021-04-15 Cedars-Sinai Medical Center Cardiosphere-derived cells and exosomes secreted by such cells in the treatment of muscular dystrophy
BR112017022666A8 (pt) 2015-04-20 2022-10-18 Tolero Pharmaceuticals Inc Preparando resposta à alvocidib por perfilamento mitocondrial
US20180120297A1 (en) 2015-04-27 2018-05-03 Dana-Farber Cancer Institute, Inc. Compositions and methods for assessing toxicity using dynamic bh3 profiling
ES2921350T3 (es) 2015-05-18 2022-08-24 Sumitomo Pharma Oncology Inc Profármacos de alvocidib que tienen biodisponibilidad aumentada
WO2017024073A1 (en) 2015-08-03 2017-02-09 Tolero Pharmaceuticals, Inc. Combination therapies for treatment of cancer
US11253551B2 (en) 2016-01-11 2022-02-22 Cedars-Sinai Medical Center Cardiosphere-derived cells and exosomes secreted by such cells in the treatment of heart failure with preserved ejection fraction
WO2017210652A1 (en) 2016-06-03 2017-12-07 Cedars-Sinai Medical Center Cdc-derived exosomes for treatment of ventricular tachyarrythmias
WO2018057542A1 (en) 2016-09-20 2018-03-29 Cedars-Sinai Medical Center Cardiosphere-derived cells and their extracellular vesicles to retard or reverse aging and age-related disorders
US11279694B2 (en) 2016-11-18 2022-03-22 Sumitomo Dainippon Pharma Oncology, Inc. Alvocidib prodrugs and their use as protein kinase inhibitors
AU2017379847B2 (en) 2016-12-19 2022-05-26 Sumitomo Pharma Oncology, Inc. Profiling peptides and methods for sensitivity profiling
EP3612191A4 (en) 2017-04-19 2020-12-30 Cedars-Sinai Medical Center METHODS AND COMPOSITIONS FOR TREATING SKELETAL MUSCLE DYSTROPHY
WO2019055579A1 (en) 2017-09-12 2019-03-21 Tolero Pharmaceuticals, Inc. TREATMENT REGIME FOR CANCERS THAT ARE INSENSITIVE TO BCL-2 INHIBITORS USING THE MCL-1 ALVOCIDIB INHIBITOR
US11660355B2 (en) 2017-12-20 2023-05-30 Cedars-Sinai Medical Center Engineered extracellular vesicles for enhanced tissue delivery
CN113490499A (zh) 2018-12-04 2021-10-08 大日本住友制药肿瘤公司 用作治疗癌症的活性剂的cdk9抑制剂及其多晶型物
WO2020191326A1 (en) 2019-03-20 2020-09-24 Sumitomo Dainippon Pharma Oncology, Inc. Treatment of acute myeloid leukemia (aml) with venetoclax failure
WO2022157548A1 (en) 2021-01-24 2022-07-28 Forrest Michael David Inhibitors of atp synthase - cosmetic and therapeutic uses

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NO312681B1 (no) 1990-08-24 2002-06-17 Univ California Fremgangsmåte for fremstilling av en farmasöytisk blanding med suppresiv virkning/aktivitet
US6251395B1 (en) * 1993-12-23 2001-06-26 W. Michael Gallatin Methods of inhibiting inflammation at the site of a central nervous system injury with alphaD-specific antibodies
FR2736915B1 (fr) 1995-07-19 1997-08-22 Rhone Poulenc Rorer Sa Variants de la proteine p53 et utilisations therapeutiques
EP0845043B1 (en) * 1995-07-28 2007-06-27 Marie Curie Cancer Care Transport proteins and their uses
US6017735A (en) * 1997-01-23 2000-01-25 Marie Curie Cancer Care Materials and methods for intracellular transport and their uses

Also Published As

Publication number Publication date
US6521455B2 (en) 2003-02-18
DE69637147T2 (de) 2008-03-06
BR9610058A (pt) 1999-07-27
US20060051869A1 (en) 2006-03-09
US20030219859A1 (en) 2003-11-27
US6184038B1 (en) 2001-02-06
DE69637147D1 (de) 2007-08-09
AU705563B2 (en) 1999-05-27
US20020039765A1 (en) 2002-04-04
CN1208438A (zh) 1999-02-17
JPH11510386A (ja) 1999-09-14
AU6623996A (en) 1997-02-26
EP0845043A1 (en) 1998-06-03
ATE365808T1 (de) 2007-07-15
CA2227786A1 (en) 1997-02-13
WO1997005265A1 (en) 1997-02-13
EP0845043B1 (en) 2007-06-27

Similar Documents

Publication Publication Date Title
MX9800719A (es) Proteinas de transporte y sus usos.
BG102554A (en) Vectors and methods for gene transfer into cells
IL123641A0 (en) Circular dna molecule with conditional origin of replication method for preparing the same and use thereof in gene therapy
GB2338237A (en) In vitro peptide or protein expression library
ZA942778B (en) Recombinant viruses, and their preparation and use in gene therapy.
CA2160131A1 (en) New Bacillus Thuringiensis Strains and Their Insecticidal Proteins
EE9800185A (et) Komplementaarsed adenoviirusvektorsüsteemid ja rakuliinid
BRPI9811940A (pt) vetor de expressão para um polipeptídeo de ligação da interleucina-18 (il-18-bp), célula hospedeira procariótica transformada com o referido vetor, processo para produção de il-18-bp, proteína de fusão compreendendo o referido polipeptídeo, bem como il-18bp modificada.
TR199501134A2 (tr) Memeli ve viral proteinleri asiri ifade edilmesi.
DK0941318T3 (da) Håndvægtformede konstruerede ekspressionssystemer til genterapi
NZ304570A (en) Neurone-restrictive silencer factor proteins, nucleic acids and antibodies thereto
WO1996007738A3 (en) Modified human c3 proteins
EP1012603A4 (en) FUNCTIONAL FRAGMENTS OF THE HIV-1 VPR PROTEIN AND METHODS OF USE
AU3677095A (en) Radioactive phosphorous labeling of proteins for targeted radiotherapy
CA2278808A1 (en) Methods for cultivating cells and propagating viruses
BR9407357A (pt) Novos tripeptideos utilizáveis em terapia cns e imune
AU1099697A (en) Novel xylanases, genes encoding them, and uses thereof
HK1024640A1 (en) Suppression of malignancy utilizing ribonucleotidereductase r1.
IT1262997B (it) Composto proteico e sequenze nucleotidiche codificanti per esso.
CA2475337A1 (en) Methods for cultivating cells and propagating viruses
WO2002006340A3 (en) Tetraspan protein and uses thereof
MX9708877A (es) P62, sus variantes, las secuencias de acidos nucleicos que los codifican, y su utilizacion en terapia genica anti-cancerosa.
UA9690A (uk) Індуктор інтерферону першого типу в культурах клітин