SI2432455T1 - Sestava, obsegajoäśa oljne kapljice - Google Patents
Sestava, obsegajoäśa oljne kapljiceInfo
- Publication number
- SI2432455T1 SI2432455T1 SI201030860T SI201030860T SI2432455T1 SI 2432455 T1 SI2432455 T1 SI 2432455T1 SI 201030860 T SI201030860 T SI 201030860T SI 201030860 T SI201030860 T SI 201030860T SI 2432455 T1 SI2432455 T1 SI 2432455T1
- Authority
- SI
- Slovenia
- Prior art keywords
- composition
- oil drops
- drops
- oil
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/436—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
- A61K38/13—Cyclosporins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1658—Proteins, e.g. albumin, gelatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
- A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
- A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
- A61K9/5047—Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Immunology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Dispersion Chemistry (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Nutrition Science (AREA)
- Medicinal Preparation (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
- Manufacturing Of Micro-Capsules (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Fats And Perfumes (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US17912109P | 2009-05-18 | 2009-05-18 | |
IE20090381 | 2009-05-18 | ||
PCT/EP2010/056838 WO2010133609A2 (en) | 2009-05-18 | 2010-05-18 | Composition comprising oil drops |
EP10720773.0A EP2432455B1 (en) | 2009-05-18 | 2010-05-18 | Composition comprising oil drops |
Publications (1)
Publication Number | Publication Date |
---|---|
SI2432455T1 true SI2432455T1 (sl) | 2015-04-30 |
Family
ID=43126572
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SI201030860T SI2432455T1 (sl) | 2009-05-18 | 2010-05-18 | Sestava, obsegajoäśa oljne kapljice |
Country Status (14)
Country | Link |
---|---|
US (5) | US9278070B2 (es) |
EP (3) | EP3300723A1 (es) |
JP (1) | JP5640079B2 (es) |
CN (2) | CN105213318A (es) |
BR (1) | BRPI1012196B1 (es) |
CA (1) | CA2762179A1 (es) |
DK (2) | DK2471518T3 (es) |
ES (2) | ES2530049T3 (es) |
GB (1) | GB2483815B (es) |
HR (1) | HRP20150110T1 (es) |
PL (1) | PL2471518T3 (es) |
SG (1) | SG176145A1 (es) |
SI (1) | SI2432455T1 (es) |
WO (1) | WO2010133609A2 (es) |
Families Citing this family (68)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2762179A1 (en) * | 2009-05-18 | 2010-11-25 | Sigmoid Pharma Limited | Composition comprising oil drops |
CN107582526A (zh) * | 2009-08-12 | 2018-01-16 | 希格默伊德药业有限公司 | 包含聚合物基质和油相的免疫调节组合物 |
GB201020032D0 (en) | 2010-11-25 | 2011-01-12 | Sigmoid Pharma Ltd | Composition |
WO2012094346A2 (en) | 2011-01-03 | 2012-07-12 | The Regents Of The University Of California | High density epidural stimulation for facilitation of locomotion, posture, voluntary movement, and recovery of autonomic, sexual, vasomotor, and cognitive function after neurological injury |
WO2012116434A1 (en) * | 2011-03-01 | 2012-09-07 | 4413261 Canada Inc. (Spencer Canada) | Two speed monolithic system for controlled release of drugs |
ITMI20111050A1 (it) | 2011-06-10 | 2012-12-11 | Sevecom Spa | Uso di emulsionanti in associazione con oleine vegetali in un alimento per animali. |
CN104220128B (zh) | 2011-11-11 | 2016-12-07 | 神经赋能科技公司 | 使运动功能、感觉功能、自主神经功能、性功能、血管舒缩功能和认知功能能够恢复的非侵入神经调节装置 |
US9724304B2 (en) * | 2012-06-14 | 2017-08-08 | Temple University—Of the Commonwealth System of Higher Education | Nanospheres for therapeutic agent delivery |
GB201212010D0 (en) | 2012-07-05 | 2012-08-22 | Sigmoid Pharma Ltd | Formulations |
MX356551B (es) | 2012-08-23 | 2018-06-04 | Grupo Medifarma S A De C V Star | Composición antiséptica, antiseborreica y exfoliante para eliminar o prevenir el acné. |
CN103054796B (zh) * | 2012-12-11 | 2014-07-16 | 山东省眼科研究所 | 一种环孢素a胶束滴眼液及其制备方法 |
GB201304662D0 (en) | 2013-03-14 | 2013-05-01 | Sigmoid Pharma Ltd | Compositions |
EP3049148B1 (en) | 2013-09-27 | 2020-05-20 | The Regents Of The University Of California | Engaging the cervical spinal cord circuitry to re-enable volitional control of hand function in tetraplegic subjects |
GB201319791D0 (en) * | 2013-11-08 | 2013-12-25 | Sigmoid Pharma Ltd | Formulations |
GB201319792D0 (en) * | 2013-11-08 | 2013-12-25 | Sigmoid Pharma Ltd | Formulations |
US10206884B2 (en) * | 2013-12-20 | 2019-02-19 | Fresenius Kabi Deutschland Gmbh | Microcapsules with polymeric coating comprising a lipid and an active agent |
GB201400442D0 (en) * | 2014-01-10 | 2014-02-26 | Sigmoid Pharma Ltd | Compositions for use in the treatment of ulcerative colitis |
CN106102724A (zh) * | 2014-03-27 | 2016-11-09 | 诺华股份有限公司 | 用于吸入活性药物成分的经喷雾干燥的水包油包固体分散系 |
US11458096B2 (en) * | 2014-04-09 | 2022-10-04 | Pulse Pharmaceuticals Pvt. Ltd. | Composition and method of producing nanoformulation of water insoluble bioactives in aqueous base |
EP2932956B1 (de) * | 2014-04-14 | 2017-12-27 | Symrise AG | Kapseln mit hoher Wirkstoffbeladung |
WO2015176780A1 (en) | 2014-05-23 | 2015-11-26 | Sigmoid Pharma Limited | Celecoxib formulations useful for treating colorectal cancer |
US20150342893A1 (en) * | 2014-05-29 | 2015-12-03 | Sigmoid Pharma Limited | Celecoxib formulations useful for treating colorectal cancer |
EA201692571A1 (ru) | 2014-07-21 | 2017-07-31 | Севеком С.П.А. | Порошкообразная эмульсия для кормов для животных |
US9687455B2 (en) | 2014-08-14 | 2017-06-27 | John Daniel Dobak | Sodium tetradecyl sulfate formulations for treatment of adipose tissue |
BR112017002223A2 (pt) * | 2014-08-15 | 2018-01-16 | Dow Global Technologies Llc | dispersão de etilcelulose e pó |
AU2015341695B2 (en) * | 2014-11-07 | 2021-07-08 | Sublimity Therapeutics Limited | Compositions comprising cyclosporin |
EP3236993B1 (en) | 2014-12-23 | 2023-09-13 | Theriva Biologics, Inc. | Methods and compositions for inhibiting or preventing adverse effects of oral antibiotics |
US9351945B1 (en) | 2015-02-27 | 2016-05-31 | John Daniel Dobak, III | Reduction of adipose tissue |
WO2016193588A1 (fr) * | 2015-05-29 | 2016-12-08 | Galderma Research & Development | Compositions comprenant au moins un principe actif disperse et des microcapsules lipidiques |
US10227527B2 (en) | 2015-12-14 | 2019-03-12 | Indizen Optical Technologies of America, LLC | Nanoemulsion optical materials |
CN108495709B (zh) | 2016-01-25 | 2021-09-03 | 三得利控股株式会社 | 含有功能性物质的胶囊及其制造方法 |
JP6103111B1 (ja) | 2016-05-24 | 2017-03-29 | 三生医薬株式会社 | 経口医薬組成物及び該組成物からなる粒子状製剤の製造方法 |
US20180008612A1 (en) * | 2016-07-11 | 2018-01-11 | Taho Pharmaceuticals Ltd. | Transdermal delivery system containing galantamine or salts thereof |
US11254773B2 (en) * | 2017-05-11 | 2022-02-22 | The Regents Of The University Of California | Nanoscale multiple emulsions and nanoparticles |
IL308650A (en) | 2017-06-21 | 2024-01-01 | Minerva Neurosciences Inc | Stomach-resistant controlled-release oral dosage forms |
DE20168827T1 (de) | 2017-06-30 | 2021-01-21 | Gtx Medical B.V. | System zur neuromodulierung |
CN111328284A (zh) | 2017-08-07 | 2020-06-23 | 芬奇治疗公司 | 用于维持和恢复健康的肠道屏障的组合物和方法 |
WO2019110400A1 (en) | 2017-12-05 | 2019-06-13 | Ecole Polytechnique Federale De Lausanne (Epfl) | A system for planning and/or providing neuromodulation |
EP3737750B1 (en) | 2018-01-09 | 2024-06-05 | Theriva Biologics, Inc. | Alkaline phosphatase agents for treatment of neurodevelopmental disorders |
AU2019224114A1 (en) | 2018-02-23 | 2020-09-10 | Finch Therapeutics Holdings Llc | Microbiome related immunotherapies |
SG11202008715WA (en) * | 2018-03-15 | 2020-10-29 | R P Scherer Technologies Llc | Enteric softgel capsules |
EP3773686B1 (en) | 2018-03-20 | 2023-06-07 | Theriva Biologics, Inc. | Alkaline phosphatase agents for treatment of radiation disorders |
US10828286B2 (en) * | 2018-05-24 | 2020-11-10 | Gm Pharmaceuticals, Inc. | Niacin and berberine compositions and methods of use thereof |
EP3653256B1 (en) | 2018-11-13 | 2022-03-30 | ONWARD Medical N.V. | Control system for movement reconstruction and/or restoration for a patient |
KR102193575B1 (ko) * | 2018-12-21 | 2021-01-04 | 주식회사 메가코스 | 오일-드롭 메이크업 화장료 조성물 |
EP3695878B1 (en) | 2019-02-12 | 2023-04-19 | ONWARD Medical N.V. | A system for neuromodulation |
WO2020203733A1 (ja) * | 2019-03-29 | 2020-10-08 | 積水化学工業株式会社 | コアシェル構造体、製剤、外用薬、テープ剤及び化粧品 |
US11525081B2 (en) | 2019-04-29 | 2022-12-13 | King Fahd University Of Petroleum And Minerals | Methods of inhibiting corrosion in acid stimulation operations |
KR20220020800A (ko) * | 2019-06-14 | 2022-02-21 | 모리시타 진탄 가부시키가이샤 | 지연 붕괴형 캡슐 및 그의 제조 방법 |
CA3146738A1 (en) | 2019-07-18 | 2021-01-21 | Synthetic Biologics, Inc. | Intestinal alkaline phosphatase-based treatments of metabolic disorders |
AU2020316330A1 (en) | 2019-07-19 | 2022-01-06 | Finch Therapeutics Holdings Llc. | Methods and products for treatment of gastrointestinal disorders |
JP2022547330A (ja) | 2019-09-13 | 2022-11-11 | フィンチ セラピューティクス ホールディングス エルエルシー | 自閉症スペクトラム障害を治療するための組成物および方法 |
CA3156240A1 (en) * | 2019-10-18 | 2021-04-22 | Quicksilver Scientific, Inc. | Self-microemulsifying multi-deliverable systems |
US20240226187A9 (en) | 2019-10-18 | 2024-07-11 | Finch Therapeutics Holdings Llc | Compositions and Methods for Delivering a Bacterial Metabolite to a Subject |
WO2021097288A1 (en) | 2019-11-15 | 2021-05-20 | Finch Therapeutics Holdings Llc | Compositions and methods for treating neurodegenerative diseases |
DE19211698T1 (de) | 2019-11-27 | 2021-09-02 | Onward Medical B.V. | Neuromodulation system |
IL271766B (en) | 2019-12-30 | 2021-04-29 | Fischer Pharma Ltd | Molded material for topical administration and its uses |
WO2021142347A1 (en) | 2020-01-10 | 2021-07-15 | Finch Therapeutics Holdings Llc | Compositions and methods for non-alcoholic steatohepatitis (nash) |
WO2021142358A1 (en) | 2020-01-10 | 2021-07-15 | Finch Therapeutics Holdings Llc | Compositions and methods for treating hepatic encephalopathy (he) |
TW202140049A (zh) | 2020-01-10 | 2021-11-01 | 美商芬奇治療控股有限責任公司 | 用於治療b型肝炎(hbv)及d型肝炎(hdv)之組合物及方法 |
JP2023520021A (ja) * | 2020-03-30 | 2023-05-15 | アイジーアイエー ファーマシューティカルズ インコーポレイテッド | チロシンキナーゼ阻害剤の小児用製剤 |
US20230201265A1 (en) | 2020-03-31 | 2023-06-29 | Finch Therapeutics Holdings Llc | Compositions comprising non-viable fecal microbiota and methods of use thereof |
EP4188366A4 (en) | 2020-07-28 | 2024-09-04 | Novelstar Pharmaceuticals Inc | NEW GASTRORETENTIVE DOSAGE FORM WITH EXTENDED RELEASE |
US20240263251A1 (en) | 2021-02-19 | 2024-08-08 | Finch Therapeutics Holdings Llc | Compositions and methods for providing secondary bile acids to a subject |
CN114532339A (zh) * | 2021-12-23 | 2022-05-27 | 武汉轻工大学 | 一种用于水产养殖的皂化包裹抗菌药物的制备方法 |
WO2024111590A1 (ja) * | 2022-11-22 | 2024-05-30 | 一丸ファルコス株式会社 | Ras阻害ペプチドを含む組成物 |
WO2024121846A1 (en) | 2022-12-05 | 2024-06-13 | Redefine Meat Ltd. | Edible lipid element, method of preparation and uses thereof |
US20240207235A1 (en) * | 2022-12-22 | 2024-06-27 | King Faisal University | Nanoemulsion formulation for treating disbetes mellitus (dm) |
Family Cites Families (222)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3536809A (en) | 1969-02-17 | 1970-10-27 | Alza Corp | Medication method |
US3598123A (en) | 1969-04-01 | 1971-08-10 | Alza Corp | Bandage for administering drugs |
US3845770A (en) | 1972-06-05 | 1974-11-05 | Alza Corp | Osmatic dispensing device for releasing beneficial agent |
US3916899A (en) | 1973-04-25 | 1975-11-04 | Alza Corp | Osmotic dispensing device with maximum and minimum sizes for the passageway |
US3971852A (en) | 1973-06-12 | 1976-07-27 | Polak's Frutal Works, Inc. | Process of encapsulating an oil and product produced thereby |
US4008719A (en) | 1976-02-02 | 1977-02-22 | Alza Corporation | Osmotic system having laminar arrangement for programming delivery of active agent |
US4045589A (en) | 1976-06-21 | 1977-08-30 | Carnation Company | Fat emulsion product and process for producing the same |
IT1090703B (it) | 1976-12-03 | 1985-06-26 | Scherer Ltd R P | Perfezionamento nelle composizioni utili quali veicolo per farmaci |
US4123403A (en) | 1977-06-27 | 1978-10-31 | The Dow Chemical Company | Continuous process for preparing aqueous polymer microsuspensions |
DE2907460A1 (de) | 1978-03-07 | 1979-09-13 | Sandoz Ag | Neue resorbierbare galenische kompositionen |
DE3013839A1 (de) | 1979-04-13 | 1980-10-30 | Freunt Ind Co Ltd | Verfahren zur herstellung einer aktivierten pharmazeutischen zusammensetzung |
US4279632A (en) | 1979-05-08 | 1981-07-21 | Nasa | Method and apparatus for producing concentric hollow spheres |
IT1148784B (it) | 1980-04-09 | 1986-12-03 | Eurand Spa | Procedimento per la preparazione di microcapsule in un veicolo liquido |
US4379454A (en) | 1981-02-17 | 1983-04-12 | Alza Corporation | Dosage for coadministering drug and percutaneous absorption enhancer |
JPS6415Y2 (es) | 1981-05-29 | 1989-01-05 | ||
DE3224619A1 (de) | 1981-07-14 | 1983-05-19 | Freund Industrial Co., Ltd., Tokyo | Orale pharmazeutische zusammensetzung |
JPS5813508A (ja) | 1981-07-14 | 1983-01-26 | Taiho Yakuhin Kogyo Kk | ポリグリセロール飽和脂肪酸エステルを含む経口薬剤組成物 |
JPS5877810A (ja) | 1981-11-01 | 1983-05-11 | Taiho Yakuhin Kogyo Kk | ポリグリセロ−ル不飽和脂肪酸エステルを含む経口薬剤組成物 |
US4481157A (en) | 1982-04-27 | 1984-11-06 | Morishita Jintan Co., Ltd. | Method and apparatus for production of microcapsules |
US4597959A (en) | 1982-04-30 | 1986-07-01 | Arthur Barr | Sustained release breath freshener, mouth and palate coolant wafer composition and method of use |
US4422985A (en) | 1982-09-24 | 1983-12-27 | Morishita Jintan Co., Ltd. | Method and apparatus for encapsulation of a liquid or meltable solid material |
JPS5988420A (ja) | 1982-11-12 | 1984-05-22 | Teisan Seiyaku Kk | シ−ムレスカプセル化ニフエジピン製剤 |
JPS5988420U (ja) | 1982-12-04 | 1984-06-15 | 有限会社三和ボタン店 | 学生服の詰襟構造 |
US4502888A (en) | 1982-12-13 | 1985-03-05 | The Dow Chemical Company | Aqueous dispersions of plasticized polymer particles |
JPS59131355A (ja) | 1983-01-17 | 1984-07-28 | 森下仁丹株式会社 | 多重軟カプセルの製法 |
HU187215B (en) | 1983-01-26 | 1985-11-28 | Egyt Gyogyszervegyeszeti Gyar | Method for producing pharmaceutical product of high actor content and prolonged effect |
DE3331009A1 (de) | 1983-08-27 | 1985-03-14 | Basf Ag, 6700 Ludwigshafen | Verfahren zur erhoehung der enteralen resorbierbarkeit von heparin bzw. heparinoiden sowie das so erhaeltliche heparin- bzw. heparinoidpraeparat |
US4615892A (en) | 1983-09-12 | 1986-10-07 | Grain Processing Corporation | Dried emulsion concentrates hydratable to edible spreads |
JPS60100516A (ja) | 1983-11-04 | 1985-06-04 | Takeda Chem Ind Ltd | 徐放型マイクロカプセルの製造法 |
US4659700A (en) | 1984-03-02 | 1987-04-21 | Johnson & Johnson Products, Inc. | Chitosan-glycerol-water gel |
JPS6115119A (ja) | 1984-07-02 | 1986-01-23 | Yokogawa Hokushin Electric Corp | レ−ザプリンタ |
IE58110B1 (en) | 1984-10-30 | 1993-07-14 | Elan Corp Plc | Controlled release powder and process for its preparation |
JPS61115462A (ja) | 1984-11-13 | 1986-06-03 | Denka Seiyaku Kk | 甘味増強ステビア葉の製法 |
JPS61126016A (ja) * | 1984-11-22 | 1986-06-13 | Toagosei Chem Ind Co Ltd | 不飽和脂肪酸を内相物としたマイクロカプセル |
US4601894A (en) | 1985-03-29 | 1986-07-22 | Schering Corporation | Controlled release dosage form comprising acetaminophen, pseudoephedrine sulfate and dexbrompheniramine maleate |
EP0241806A1 (en) | 1986-04-14 | 1987-10-21 | Fujisawa Pharmaceutical Co., Ltd. | Sustained-release transdermal delivery preparations |
US4857335A (en) | 1987-03-27 | 1989-08-15 | Lim Technology Laboratories, Inc. | Liquid controlled release formulations and method of producing same via multiple emulsion process |
US4891223A (en) | 1987-09-03 | 1990-01-02 | Air Products And Chemicals, Inc. | Controlled release delivery coating formulation for bioactive substances |
DE3851152T2 (de) | 1987-09-03 | 1995-01-26 | Univ Georgia | Cyclosporin-augenmittel. |
US4910191A (en) | 1988-06-28 | 1990-03-20 | Merrell Dow Pharmaceuticals Inc. | 19-substituted progesterone derivatives useful as 19-hydroxylase inhibitors |
US5073543A (en) | 1988-07-21 | 1991-12-17 | G. D. Searle & Co. | Controlled release formulations of trophic factors in ganglioside-lipsome vehicle |
US5350741A (en) | 1988-07-30 | 1994-09-27 | Kanji Takada | Enteric formulations of physiologically active peptides and proteins |
US5342625A (en) | 1988-09-16 | 1994-08-30 | Sandoz Ltd. | Pharmaceutical compositions comprising cyclosporins |
KR0148748B1 (ko) | 1988-09-16 | 1998-08-17 | 장 크라메르, 한스 루돌프 하우스 | 사이클로스포린을 함유하는 약학조성물 |
IT1229203B (it) | 1989-03-22 | 1991-07-25 | Bioresearch Spa | Impiego di acido 5 metiltetraidrofolico, di acido 5 formiltetraidrofolico e dei loro sali farmaceuticamente accettabili per la preparazione di composizioni farmaceutiche in forma a rilascio controllato attive nella terapia dei disturbi mentali organici e composizioni farmaceutiche relative. |
US5133974A (en) | 1989-05-05 | 1992-07-28 | Kv Pharmaceutical Company | Extended release pharmaceutical formulations |
JP2806564B2 (ja) | 1989-07-20 | 1998-09-30 | 森下仁丹株式会社 | 親水性物質を内容物とするシームレスカプセルおよびその製法 |
GB2237510B (en) | 1989-11-04 | 1993-09-15 | Danbiosyst Uk | Small particle drug compositions for nasal administration |
US5120548A (en) | 1989-11-07 | 1992-06-09 | Merck & Co., Inc. | Swelling modulated polymeric drug delivery device |
US5260071A (en) | 1989-12-18 | 1993-11-09 | Lemelson Jerome H | Drug units and methods for using same |
US5733566A (en) | 1990-05-15 | 1998-03-31 | Alkermes Controlled Therapeutics Inc. Ii | Controlled release of antiparasitic agents in animals |
ES2138588T3 (es) * | 1990-06-29 | 2000-01-16 | Chiron Corp | Composiciones de vacunas que contienen liposomas. |
DK0465238T3 (da) | 1990-07-04 | 1994-05-02 | Shionogi & Co | Fremgangsmåde til fremstilling af ikke-kohæsive overtræk |
US5418010A (en) | 1990-10-05 | 1995-05-23 | Griffith Laboratories Worldwide, Inc. | Microencapsulation process |
US5102668A (en) | 1990-10-05 | 1992-04-07 | Kingaform Technology, Inc. | Sustained release pharmaceutical preparation using diffusion barriers whose permeabilities change in response to changing pH |
US5145684A (en) | 1991-01-25 | 1992-09-08 | Sterling Drug Inc. | Surface modified drug nanoparticles |
GB9113872D0 (en) | 1991-06-27 | 1991-08-14 | Sandoz Ag | Improvements in or relating to organic compounds |
ATE161707T1 (de) | 1991-06-28 | 1998-01-15 | Univ Brown Res Found | Kapselextrusionssysteme |
JP3313124B2 (ja) | 1991-07-31 | 2002-08-12 | 森下仁丹株式会社 | 親水性物質を内容物とするシームレスカプセルおよびその製法 |
JPH0549899A (ja) | 1991-08-09 | 1993-03-02 | Japan Tobacco Inc | ビーズ及びこれを製造するための液滴生成装置 |
US5580578A (en) | 1992-01-27 | 1996-12-03 | Euro-Celtique, S.A. | Controlled release formulations coated with aqueous dispersions of acrylic polymers |
AU666895B2 (en) | 1991-12-30 | 1996-02-29 | Hercules Incorporated | High load spray dry encapsulation |
ATE156350T1 (de) * | 1992-01-17 | 1997-08-15 | Alfatec Pharma Gmbh | Peptidarzneistoffe enthaltende pellets und ihre herstellung sowie deren verwendung |
DE4201179A1 (de) | 1992-01-17 | 1993-07-22 | Alfatec Pharma Gmbh | Wirkstoff(e) enthaltendes granulat oder pellet mit einem geruest aus hydrophilen makromolekuelen und verfahren zu seiner herstellung |
US5571533A (en) | 1992-02-07 | 1996-11-05 | Recordati, S.A., Chemical And Pharmaceutical Company | Controlled-release mucoadhesive pharmaceutical composition for the oral administration of furosemide |
EP0573978B1 (en) | 1992-06-12 | 1999-04-21 | Kao Corporation | Bath additive composition comprising surfactant-containing seamless capsules and method for producing the capsules. |
JP3405746B2 (ja) | 1992-10-28 | 2003-05-12 | フロイント産業株式会社 | シームレスカプセルの製造方法 |
EP0678035B9 (en) | 1993-01-08 | 2006-12-13 | Csl Limited | Vaccine preparations |
GB9300875D0 (en) | 1993-01-18 | 1993-03-10 | Ucb Sa | Nanocapsule containing pharmaceutical compositions |
US5591767A (en) | 1993-01-25 | 1997-01-07 | Pharmetrix Corporation | Liquid reservoir transdermal patch for the administration of ketorolac |
US5914132A (en) | 1993-02-26 | 1999-06-22 | The Procter & Gamble Company | Pharmaceutical dosage form with multiple enteric polymer coatings for colonic delivery |
US5686105A (en) | 1993-10-19 | 1997-11-11 | The Procter & Gamble Company | Pharmaceutical dosage form with multiple enteric polymer coatings for colonic delivery |
JPH06254382A (ja) | 1993-03-05 | 1994-09-13 | Riken Vitamin Co Ltd | マイクロカプセルの製造法およびその製造装置 |
US5843347A (en) | 1993-03-23 | 1998-12-01 | Laboratoire L. Lafon | Extrusion and freeze-drying method for preparing particles containing an active ingredient |
CN1077800C (zh) | 1993-07-01 | 2002-01-16 | 韩美药品工业株式会社 | 环孢菌素软胶囊组合物 |
FR2707184B1 (fr) | 1993-07-08 | 1995-08-11 | Rhone Poulenc Nutrition Animal | Procédé de préparation de sphérules contenant un principe actif alimentaire ou pharmaceutique. |
US5562909A (en) | 1993-07-12 | 1996-10-08 | Massachusetts Institute Of Technology | Phosphazene polyelectrolytes as immunoadjuvants |
DE4329503A1 (de) | 1993-09-01 | 1995-03-02 | Galenik Labor Freiburg Gmbh | Pharmazeutische Präparate zur gezielten Behandlung von Morbus Crohn und Colitis Ulcerosa |
DE4332041C2 (de) | 1993-09-21 | 1997-12-11 | Rentschler Arzneimittel | Verwendung von Pentoxifyllin bei bestimmten Lungenerkrankungen |
US5961970A (en) | 1993-10-29 | 1999-10-05 | Pharmos Corporation | Submicron emulsions as vaccine adjuvants |
WO1995022343A1 (fr) | 1994-02-17 | 1995-08-24 | Shiseido Company, Ltd. | Composition d'emulsion a base de cyclosporine |
US5498439A (en) | 1994-03-04 | 1996-03-12 | Arnhem, Inc. | Process for encapsulating the flavor with colloid gel matrix |
GB9405304D0 (en) | 1994-03-16 | 1994-04-27 | Scherer Ltd R P | Delivery systems for hydrophobic drugs |
FR2721510B1 (fr) | 1994-06-22 | 1996-07-26 | Rhone Poulenc Rorer Sa | Nanoparticules filtrables dans des conditions stériles. |
IT1270594B (it) | 1994-07-07 | 1997-05-07 | Recordati Chem Pharm | Composizione farmaceutica a rilascio controllato di moguisteina in sospensione liquida |
US5650232A (en) | 1994-10-07 | 1997-07-22 | Warner-Lambert Company | Method for making seamless capsules |
FR2725623A1 (fr) | 1994-10-18 | 1996-04-19 | Flamel Tech Sa | Microcapsules medicamenteuses et/ou nutritionnelles pour administration per os |
US5827531A (en) | 1994-12-02 | 1998-10-27 | The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration | Microcapsules and methods for making |
US5529783A (en) | 1994-12-19 | 1996-06-25 | Mcneil-Ppc, Inc. | Rotor granulation and coating of acetaminophen, pseudoephedrine, chlorpheniramine, and, optionally dextromethorphan |
KR0167613B1 (ko) | 1994-12-28 | 1999-01-15 | 한스 루돌프 하우스, 니콜 케르커 | 사이클로스포린-함유 연질캅셀제 조성물 |
US5510118A (en) | 1995-02-14 | 1996-04-23 | Nanosystems Llc | Process for preparing therapeutic compositions containing nanoparticles |
US5674495A (en) | 1995-02-27 | 1997-10-07 | Purdue Research Foundation | Alginate-based vaccine compositions |
US5595757A (en) | 1995-03-29 | 1997-01-21 | Warner-Lambert Company | Seamless capsules |
US5665386A (en) | 1995-06-07 | 1997-09-09 | Avmax, Inc. | Use of essential oils to increase bioavailability of oral pharmaceutical compounds |
US5716928A (en) | 1995-06-07 | 1998-02-10 | Avmax, Inc. | Use of essential oils to increase bioavailability of oral pharmaceutical compounds |
IE80467B1 (en) | 1995-07-03 | 1998-07-29 | Elan Corp Plc | Controlled release formulations for poorly soluble drugs |
SE504582C2 (sv) | 1995-07-06 | 1997-03-10 | Gs Dev Ab | Cyklosporinkomposition baserad på en L2-fas |
BR9606603A (pt) | 1995-08-25 | 1997-09-30 | Sangstat Medical Corp | Formulação de ciclosporina dispersão aquosa de nanopartículas de ciclosporina kit e processo de preparação de dispersão aquosa de partículas de ciclosporina |
EP0760237A1 (en) | 1995-08-30 | 1997-03-05 | Cipla Limited | Oil-in-water microemulsions |
DE19549852B4 (de) | 1995-11-29 | 2009-06-04 | Novartis Ag | Cyclosporin enthaltende Präparate |
JP3759986B2 (ja) | 1995-12-07 | 2006-03-29 | フロイント産業株式会社 | シームレスカプセルおよびその製造方法 |
US5858401A (en) | 1996-01-22 | 1999-01-12 | Sidmak Laboratories, Inc. | Pharmaceutical composition for cyclosporines |
US5686133A (en) | 1996-01-31 | 1997-11-11 | Port Systems, L.L.C. | Water soluble pharmaceutical coating and method for producing coated pharmaceuticals |
US5958876A (en) | 1996-06-19 | 1999-09-28 | Novartis Ag | Cyclosporin-containing pharmaceutical compositions |
KR0183449B1 (ko) | 1996-06-19 | 1999-05-01 | 한스 루돌프 하우스, 니콜 케르커 | 사이클로스포린-함유 연질캅셀제 |
ES2565163T3 (es) | 1996-10-28 | 2016-03-31 | General Mills, Inc. | Imbibición y encapsulación de partículas de liberación controlada y producto encapsulado |
US5891474A (en) | 1997-01-29 | 1999-04-06 | Poli Industria Chimica, S.P.A. | Time-specific controlled release dosage formulations and method of preparing same |
JP2001515491A (ja) | 1997-03-12 | 2001-09-18 | アボツト・ラボラトリーズ | 親油性化合物の投与のための親油性二成分系 |
DZ2479A1 (fr) | 1997-05-05 | 2003-02-01 | Pfizer | Composés inhibiteurs sélectifs de cox-2 anti-inflammatoires et compositions pharmaceutiques les contenant. |
AU7201998A (en) | 1997-05-06 | 1998-11-27 | Zhi Liu | Drug delivery system |
JP4102459B2 (ja) | 1997-05-14 | 2008-06-18 | 森下仁丹株式会社 | 生体高分子を合成するシームレスカプセルおよびその製造方法 |
SE9702533D0 (sv) | 1997-07-01 | 1997-07-01 | Astra Ab | New oral formulation |
BR9811058A (pt) | 1997-07-29 | 2000-09-05 | Upjohn Co | Formulação auto-emulsificante para compostos lipofìlicos |
ES2137862B1 (es) | 1997-07-31 | 2000-09-16 | Intexim S A | Preparacion farmaceutica oral que comprende un compuesto de actividad antiulcerosa y procedimiento para su obtencion. |
JP3090198B2 (ja) | 1997-08-21 | 2000-09-18 | 日本電気株式会社 | 半導体装置の構造およびその製造方法 |
HUP9701554D0 (en) | 1997-09-18 | 1997-11-28 | Human Oltoanyagtermeloe Gyogys | Pharmaceutical composition containing plazma proteins |
EP1025842B1 (en) | 1997-10-30 | 2004-07-21 | Morishita Jintan Co., Ltd. | Double-leyered capsule of unsaturated fatty acid or derivative thereof and process for producing the same |
IT1296585B1 (it) | 1997-11-28 | 1999-07-14 | Uni Di Pavia | Microcapsule contenenti materiale seminale per l'inseminazione strumentale nella specie suina |
US6509346B2 (en) | 1998-01-21 | 2003-01-21 | Millennium Pharmaceuticals, Inc. | Chemokine receptor antagonists and methods of use therefor |
US20040062802A1 (en) | 1998-04-02 | 2004-04-01 | Hermelin Victor M. | Maximizing effectiveness of substances used to improve health and well being |
US6174466B1 (en) | 1998-05-08 | 2001-01-16 | Warner-Lambert Company | Methods for making seamless capsules |
JPH11322587A (ja) | 1998-05-18 | 1999-11-24 | Sumitomo Chem Co Ltd | 常温で固体の生理活性物質のマイクロカプセル化方法およびこの方法により得られるマイクロカプセル組成物 |
US20040166183A1 (en) * | 1998-05-20 | 2004-08-26 | Ruseler-Van Embden Johanna G. H. | Methods and means for preventing or treating inflammation or pruritis |
KR100336090B1 (ko) | 1998-06-27 | 2002-05-27 | 윤승원 | 오일, 지방산 또는 이들의 혼합물을 함유한 난용성 약물의 고형분산제제 |
DE19848849A1 (de) | 1998-10-22 | 2000-04-27 | Knoll Ag | Verfahren zur Herstellung von festen, sphärischen Formen, enthaltend eine biologisch aktive Substanz |
PL348193A1 (en) | 1998-12-11 | 2002-05-06 | Pharmasolutions | Self-emulsifying compositions for drugs poorly soluble in water |
JP3039863B1 (ja) | 1998-12-25 | 2000-05-08 | 不二精工株式会社 | ロッキングプレス装置 |
US20030104048A1 (en) | 1999-02-26 | 2003-06-05 | Lipocine, Inc. | Pharmaceutical dosage forms for highly hydrophilic materials |
US6294192B1 (en) | 1999-02-26 | 2001-09-25 | Lipocine, Inc. | Triglyceride-free compositions and methods for improved delivery of hydrophobic therapeutic agents |
US6248363B1 (en) | 1999-11-23 | 2001-06-19 | Lipocine, Inc. | Solid carriers for improved delivery of active ingredients in pharmaceutical compositions |
JP2000247911A (ja) | 1999-02-26 | 2000-09-12 | Hisamitsu Pharmaceut Co Inc | 大腸用吸収促進剤 |
US6267985B1 (en) | 1999-06-30 | 2001-07-31 | Lipocine Inc. | Clear oil-containing pharmaceutical compositions |
US7374779B2 (en) | 1999-02-26 | 2008-05-20 | Lipocine, Inc. | Pharmaceutical formulations and systems for improved absorption and multistage release of active agents |
US6761903B2 (en) | 1999-06-30 | 2004-07-13 | Lipocine, Inc. | Clear oil-containing pharmaceutical compositions containing a therapeutic agent |
JP2000302654A (ja) | 1999-04-16 | 2000-10-31 | Kao Corp | 歯磨組成物の製造法 |
US8663692B1 (en) | 1999-05-07 | 2014-03-04 | Pharmasol Gmbh | Lipid particles on the basis of mixtures of liquid and solid lipids and method for producing same |
WO2000069420A1 (en) | 1999-05-14 | 2000-11-23 | Coraltis Ltd. | Pulse-delivery oral compositions |
EP1184038B1 (en) | 1999-06-09 | 2005-12-28 | Mochida Pharmaceutical Co., Ltd. | System for release in lower digestive tract |
PT1183014E (pt) | 1999-06-14 | 2003-12-31 | Cosmo Spa | Composicoes farmaceuticas orais de libertacao controlada e de dissimulacao de sabor |
US6309663B1 (en) | 1999-08-17 | 2001-10-30 | Lipocine Inc. | Triglyceride-free compositions and methods for enhanced absorption of hydrophilic therapeutic agents |
US6458383B2 (en) | 1999-08-17 | 2002-10-01 | Lipocine, Inc. | Pharmaceutical dosage form for oral administration of hydrophilic drugs, particularly low molecular weight heparin |
US20030235595A1 (en) | 1999-06-30 | 2003-12-25 | Feng-Jing Chen | Oil-containing, orally administrable pharmaceutical composition for improved delivery of a therapeutic agent |
US20030236236A1 (en) | 1999-06-30 | 2003-12-25 | Feng-Jing Chen | Pharmaceutical compositions and dosage forms for administration of hydrophobic drugs |
CA2391707C (en) | 1999-07-30 | 2010-05-11 | Smithkline Beecham Plc | Multi-component pharmaceutical dosage form |
EP1227793A1 (en) | 1999-11-02 | 2002-08-07 | Cipla Ltd. | Cyclosporin formulation |
US20060034937A1 (en) * | 1999-11-23 | 2006-02-16 | Mahesh Patel | Solid carriers for improved delivery of active ingredients in pharmaceutical compositions |
US20030180352A1 (en) | 1999-11-23 | 2003-09-25 | Patel Mahesh V. | Solid carriers for improved delivery of active ingredients in pharmaceutical compositions |
EP1244468A2 (en) | 2000-01-07 | 2002-10-02 | University Of Cincinnati | Selective activation of a th1 or th2 lymphocyte regulated immune response |
JP2003531930A (ja) | 2000-04-28 | 2003-10-28 | ユニバーシティ・カレッジ・ダブリン | 両親媒性大環状誘導体およびそれらの類似体 |
ES2243497T3 (es) | 2000-05-12 | 2005-12-01 | PHARMACIA & UPJOHN COMPANY LLC | Composicion de vacuna, procedimiento de preparacion de la misma y procedimiento para vacunacion de vertebrados. |
US20040258702A1 (en) | 2000-06-22 | 2004-12-23 | Blonder Joan P. | Vaccine delivery |
GB0018527D0 (en) | 2000-07-27 | 2000-09-13 | Photocure Asa | Composition |
US6565888B1 (en) | 2000-08-23 | 2003-05-20 | Alkermes Controlled Therapeutics, Inc. | Methods and compositions for the targeted delivery of biologically active agents |
FI20002215A0 (fi) | 2000-10-06 | 2000-10-06 | Orion Yhtymae Oyj | Yhdistelmäpartikkelit |
EP1372708B1 (en) | 2001-02-13 | 2008-06-18 | GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY OF THE ARMY | Vaccine for transcutaneous immunization against travellers' diarrhoea |
CN1203843C (zh) * | 2001-04-10 | 2005-06-01 | 中国科学院成都有机化学研究所 | 一种高含量油溶性维生素缓释微囊粉的制备方法 |
ITMI20011337A1 (it) | 2001-06-26 | 2002-12-26 | Farmatron Ltd | Composizioni farmaceutiche orali a rilascio modificato del principio attivo |
WO2003009812A2 (en) | 2001-07-25 | 2003-02-06 | New York University | Use of glycosylceramides as adjuvants for vaccines against infections and cancer |
US6585997B2 (en) | 2001-08-16 | 2003-07-01 | Access Pharmaceuticals, Inc. | Mucoadhesive erodible drug delivery device for controlled administration of pharmaceuticals and other active compounds |
US20030083286A1 (en) | 2001-08-22 | 2003-05-01 | Ching-Leou Teng | Bioadhesive compositions and methods for enhanced intestinal drug absorption |
US6669955B2 (en) | 2001-08-28 | 2003-12-30 | Longwood Pharmaceutical Research, Inc. | Combination dosage form containing individual dosage units of a cholesterol-lowering agent, an inhibitor of the renin-angiotensin system, and aspirin |
FR2830447B1 (fr) | 2001-10-09 | 2004-04-16 | Flamel Tech Sa | Forme galenique orale microparticulaire pour la liberation retardee et controlee de principes actifs pharmaceutiques |
US6951655B2 (en) | 2001-10-11 | 2005-10-04 | Imi Biomed, Inc. | Pro-micelle pharmaceutical compositions |
US20040126428A1 (en) | 2001-11-02 | 2004-07-01 | Lyn Hughes | Pharmaceutical formulation including a resinate and an aversive agent |
EP1455753A1 (en) | 2001-12-20 | 2004-09-15 | Bernard Charles Sherman | Pharmaceutical compositions comprising a cyclosporin, a hydrophilic surfactant and a lipophilic surfactant |
WO2003056938A1 (en) | 2002-01-10 | 2003-07-17 | Firmenich Sa | Process for the preparation of extruded delivery systems |
US6949256B2 (en) | 2002-01-18 | 2005-09-27 | Banner Pharmacaps, Inc. | Non-gelatin capsule shell formulation |
US6974592B2 (en) | 2002-04-11 | 2005-12-13 | Ocean Nutrition Canada Limited | Encapsulated agglomeration of microcapsules and method for the preparation thereof |
US20030207907A1 (en) | 2002-05-03 | 2003-11-06 | Iversen Patrick L. | Delivery of microparticle-conjugated drugs for inhibition of stenosis |
JP4226846B2 (ja) | 2002-06-07 | 2009-02-18 | キャタレント・ジャパン株式会社 | 口腔内で崩壊可能なソフトカプセル剤 |
JP2004043332A (ja) | 2002-07-09 | 2004-02-12 | Nof Corp | 経口用リポソーム製剤 |
GB2391473B (en) | 2002-08-02 | 2004-07-07 | Satishchandra Punambhai Patel | Pharmaceutical compositions |
GB2408729A (en) | 2002-09-04 | 2005-06-08 | Southwest Res Inst | Microencapsulation of oxygen or water sensitive materials |
AU2003291678B2 (en) | 2002-11-01 | 2009-01-15 | The Trustees Of The University Of Pennsylvania | Compositions and methods for siRNA inhibition of HIF-1 alpha |
US7524515B2 (en) | 2003-01-10 | 2009-04-28 | Mutual Pharmaceuticals, Inc. | Pharmaceutical safety dosage forms |
WO2004064997A1 (en) | 2003-01-23 | 2004-08-05 | Inotech Ag | New microcapsules useful as extraction means in particular for extracting water or soil contaminants |
ES2665464T3 (es) | 2003-03-28 | 2018-04-25 | Sigmoid Pharma Limited | Forma de dosificación oral sólida que contiene microcápsulas sin costuras |
WO2004087204A2 (en) | 2003-04-04 | 2004-10-14 | Pfizer Products Inc. | Microfluidized oil-in-water emulsions and vaccine compositions |
US8614204B2 (en) | 2003-06-06 | 2013-12-24 | Fibrogen, Inc. | Enhanced erythropoiesis and iron metabolism |
BRPI0413927B8 (pt) | 2003-08-29 | 2021-05-25 | Lifecycle Pharma As | composição farmacêutica compreendendo tacrolimus, forma de dosagem, uso da composição, e, método para a preparação da composição |
US7087237B2 (en) | 2003-09-19 | 2006-08-08 | Advanced Ocular Systems Limited | Ocular solutions |
US20050095288A1 (en) | 2003-11-03 | 2005-05-05 | Andrx Labs, Llc | Decongestant and expectorant tablets |
WO2005048998A1 (en) | 2003-11-21 | 2005-06-02 | Commonwealth Scientific & Industrial Research Organisation | G i tract delivery systems |
US20050244505A1 (en) | 2003-12-11 | 2005-11-03 | Higbee Russell G | Immunotherapy compositions, method of making and method of use thereof |
CN1268325C (zh) | 2004-01-18 | 2006-08-09 | 浙江大学 | 三重复合微球制剂及其制备方法 |
CN1897930A (zh) | 2004-01-30 | 2007-01-17 | 血管技术国际股份公司 | 用于治疗挛缩的组合物和方法 |
PE20060003A1 (es) | 2004-03-12 | 2006-03-01 | Smithkline Beecham Plc | Formulacion farmaceutica polimerica para moldear por inyeccion |
FR2867395B1 (fr) | 2004-03-15 | 2006-06-16 | Rhodia Chimie Sa | Emulsion sechee, son procede de preparation, et ses utilisations |
US7709025B2 (en) | 2004-03-31 | 2010-05-04 | Bpsi Holdings, Inc. | Enteric coatings for orally ingestible substrates |
PL1746980T3 (pl) | 2004-05-07 | 2012-03-30 | Nycomed Gmbh | Farmaceutyczna postać dawkowania zawierająca peletki i sposób jej wytwarzania |
GB0417481D0 (en) | 2004-08-05 | 2004-09-08 | Etiologics Ltd | Combination therapy |
CN100486567C (zh) * | 2004-08-12 | 2009-05-13 | 山东绿叶天然药物研究开发有限公司 | 姜黄素乳剂及其制备方法 |
KR101398747B1 (ko) * | 2004-08-19 | 2014-05-26 | 디에스엠 아이피 어셋츠 비.브이. | 지용성 물질의 신규한 조성물 |
WO2006026592A2 (en) | 2004-08-27 | 2006-03-09 | Spherics, Inc. | Oral administration of poorly absorbed drugs, methods and compositions related thereto |
US20060135441A1 (en) | 2004-09-02 | 2006-06-22 | Bionaut Pharmaceuticals, Inc. | Combinatorial chemotherapy treatment using Na+/K+ ATPase inhibitors |
GB0419846D0 (en) | 2004-09-07 | 2004-10-13 | Chiron Srl | Vaccine adjuvants for saccharides |
EP2444071A1 (en) | 2004-09-27 | 2012-04-25 | Sigmoid Pharma Limited | Minicapsule formulations |
WO2006104703A1 (en) | 2005-03-29 | 2006-10-05 | Mcneil-Ppc, Inc. | Compositions with hydrophilic drugs in a hydrophobic medium |
MX2007012762A (es) | 2005-04-12 | 2008-01-14 | Elan Pharma Int Ltd | Composiciones de material nanoparticulado y de liberacion controlada que comprende ciclosporina. |
KR100764678B1 (ko) | 2005-07-13 | 2007-10-09 | 재단법인서울대학교산학협력재단 | 알파-갈락토실세라마이드를 아쥬반트로 포함하는 비강투여용 백신 조성물 |
TW200800305A (en) | 2005-07-26 | 2008-01-01 | Glaxo Group Ltd | Encapsulation of lipid-based formulations in enteric polymers |
EP1909771A1 (en) | 2005-08-02 | 2008-04-16 | Miv Therapeutics Inc. | Microdevices comprising nanocapsules for controlled delivery of drugs and method of manufacturing same |
EP1776963A1 (en) * | 2005-10-19 | 2007-04-25 | Gbf-Gesellschaft Für Biotechnologische Forschung Mbh | Hexosylceramides as adjuvants and their uses in pharmaceutical compositions |
US7842312B2 (en) | 2005-12-29 | 2010-11-30 | Cordis Corporation | Polymeric compositions comprising therapeutic agents in crystalline phases, and methods of forming the same |
DK2777695T3 (en) | 2006-02-09 | 2018-12-17 | Alba Therapeutics Corp | Formulations for a tight-junction effector |
US8039010B2 (en) | 2006-11-03 | 2011-10-18 | Allergan, Inc. | Sustained release intraocular drug delivery systems comprising a water soluble therapeutic agent and a release modifier |
US20080124279A1 (en) | 2006-11-17 | 2008-05-29 | Antoine Andremont | Colonic delivery using Zn/pectin beads with a Eudragit coating |
EP2066309B1 (en) | 2007-04-04 | 2012-08-29 | Sigmoid Pharma Limited | An oral pharmaceutical composition |
SI2144998T1 (sl) | 2007-04-06 | 2017-05-31 | Takeda Vaccines, Inc. | Postopki in sestavki za žive atenuirane viruse |
EP2061587A1 (en) | 2007-04-26 | 2009-05-27 | Sigmoid Pharma Limited | Manufacture of multiple minicapsules |
CN101028281B (zh) * | 2007-04-29 | 2010-05-26 | 于学敏 | 纳米胶体果胶铋及其颗粒剂药物 |
CA2685593A1 (en) | 2007-05-01 | 2008-11-06 | Sigmoid Pharma Limited | Combination pharmaceutical compositions |
US9833510B2 (en) | 2007-06-12 | 2017-12-05 | Johnson & Johnson Consumer Inc. | Modified release solid or semi-solid dosage forms |
US8962530B2 (en) | 2007-06-27 | 2015-02-24 | Regents Of The University Of Colorado | Inflammatory bowel disease therapies |
CA2702344C (en) | 2007-10-12 | 2016-09-27 | Luigi Panza | Analogues of glycolipids useful as immunoadjuvants |
CN101167704A (zh) * | 2007-11-26 | 2008-04-30 | 沈阳药科大学 | 一种诺西肽掩味微囊及其制备方法 |
EP2105129B1 (en) | 2008-03-24 | 2018-01-17 | Intervet International B.V. | Encapsulated Vaccines for the Oral Vaccination and Boostering of Fish and Other Animals |
CA2729948C (en) | 2008-07-08 | 2021-11-23 | Lifecycle Pharma A/S | Tacrolimus for improved treatment of transplant patients |
WO2010043630A2 (en) * | 2008-10-13 | 2010-04-22 | Sigmoid Pharma Limited | A delivery system for rna |
CA2762179A1 (en) * | 2009-05-18 | 2010-11-25 | Sigmoid Pharma Limited | Composition comprising oil drops |
CN107582526A (zh) * | 2009-08-12 | 2018-01-16 | 希格默伊德药业有限公司 | 包含聚合物基质和油相的免疫调节组合物 |
GB201212010D0 (en) * | 2012-07-05 | 2012-08-22 | Sigmoid Pharma Ltd | Formulations |
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- 2010-05-18 DK DK12162237.7T patent/DK2471518T3/en active
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- 2010-05-18 EP EP10720773.0A patent/EP2432455B1/en active Active
- 2010-05-18 BR BRPI1012196-0A patent/BRPI1012196B1/pt active IP Right Grant
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- 2010-05-18 JP JP2012511267A patent/JP5640079B2/ja active Active
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Also Published As
Publication number | Publication date |
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GB2483815A (en) | 2012-03-21 |
PL2471518T3 (pl) | 2018-01-31 |
EP2471518A3 (en) | 2012-12-26 |
ES2530049T3 (es) | 2015-02-26 |
DK2432455T3 (en) | 2015-02-16 |
EP2432455A2 (en) | 2012-03-28 |
US20180264076A1 (en) | 2018-09-20 |
EP3300723A1 (en) | 2018-04-04 |
GB2483815B (en) | 2013-12-25 |
EP2432455B1 (en) | 2014-11-12 |
US20160143989A1 (en) | 2016-05-26 |
EP2471518B1 (en) | 2017-08-23 |
WO2010133609A2 (en) | 2010-11-25 |
BRPI1012196B1 (pt) | 2021-11-30 |
CN105213318A (zh) | 2016-01-06 |
DK2471518T3 (en) | 2017-12-04 |
JP2012527425A (ja) | 2012-11-08 |
CA2762179A1 (en) | 2010-11-25 |
CN102470106B (zh) | 2015-09-23 |
CN102470106A (zh) | 2012-05-23 |
WO2010133609A3 (en) | 2011-12-01 |
SG176145A1 (en) | 2011-12-29 |
ES2649112T3 (es) | 2018-01-10 |
US9999651B2 (en) | 2018-06-19 |
US20210338768A1 (en) | 2021-11-04 |
JP5640079B2 (ja) | 2014-12-10 |
US20240115657A1 (en) | 2024-04-11 |
US9278070B2 (en) | 2016-03-08 |
BRPI1012196A2 (pt) | 2018-02-27 |
HRP20150110T1 (hr) | 2015-05-08 |
US20120141531A1 (en) | 2012-06-07 |
EP2471518A2 (en) | 2012-07-04 |
GB201121682D0 (en) | 2012-01-25 |
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