IT1148784B - Procedimento per la preparazione di microcapsule in un veicolo liquido - Google Patents

Procedimento per la preparazione di microcapsule in un veicolo liquido

Info

Publication number
IT1148784B
IT1148784B IT21271/80A IT2127180A IT1148784B IT 1148784 B IT1148784 B IT 1148784B IT 21271/80 A IT21271/80 A IT 21271/80A IT 2127180 A IT2127180 A IT 2127180A IT 1148784 B IT1148784 B IT 1148784B
Authority
IT
Italy
Prior art keywords
liquid vehicle
procedure
preparation
micro capsules
ionic
Prior art date
Application number
IT21271/80A
Other languages
English (en)
Other versions
IT8021271A0 (it
Inventor
Massimo Calanchi
Original Assignee
Eurand Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eurand Spa filed Critical Eurand Spa
Publication of IT8021271A0 publication Critical patent/IT8021271A0/it
Priority to IT21271/80A priority Critical patent/IT1148784B/it
Priority to AT81200354T priority patent/ATE8344T1/de
Priority to DE8181200354T priority patent/DE3164666D1/de
Priority to EP81200354A priority patent/EP0038585B1/en
Priority to US06/250,406 priority patent/US4460563A/en
Priority to JP5190081A priority patent/JPS56161833A/ja
Priority to ES501212A priority patent/ES501212A0/es
Priority to CA000375086A priority patent/CA1162111A/en
Priority to DK160881A priority patent/DK158568C/da
Application granted granted Critical
Publication of IT1148784B publication Critical patent/IT1148784B/it

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
    • Y10T428/2989—Microcapsule with solid core [includes liposome]

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Medicinal Preparation (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Jellies, Jams, And Syrups (AREA)
IT21271/80A 1980-04-09 1980-04-09 Procedimento per la preparazione di microcapsule in un veicolo liquido IT1148784B (it)

Priority Applications (9)

Application Number Priority Date Filing Date Title
IT21271/80A IT1148784B (it) 1980-04-09 1980-04-09 Procedimento per la preparazione di microcapsule in un veicolo liquido
AT81200354T ATE8344T1 (de) 1980-04-09 1981-03-31 Verfahren zum herstellen von mikrokapseln in einem fluessigen traegermaterial.
DE8181200354T DE3164666D1 (en) 1980-04-09 1981-03-31 Process for preparing microcapsules in a liquid vehicle
EP81200354A EP0038585B1 (en) 1980-04-09 1981-03-31 Process for preparing microcapsules in a liquid vehicle
US06/250,406 US4460563A (en) 1980-04-09 1981-04-02 Process for preparing microcapsules in a liquid vehicle
JP5190081A JPS56161833A (en) 1980-04-09 1981-04-08 Preparation of microcapsule in liquid vehicle
ES501212A ES501212A0 (es) 1980-04-09 1981-04-09 Procedimiento de preparacion de microcapsulas en un vehiculoliquido
CA000375086A CA1162111A (en) 1980-04-09 1981-04-09 Process for preparing microcapsules with a cellulose phthalate wall in a liquid vehicle
DK160881A DK158568C (da) 1980-04-09 1981-04-09 Fremgangsmaade til fremstilling af mikrokapsler i en flydende baerer

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT21271/80A IT1148784B (it) 1980-04-09 1980-04-09 Procedimento per la preparazione di microcapsule in un veicolo liquido

Publications (2)

Publication Number Publication Date
IT8021271A0 IT8021271A0 (it) 1980-04-09
IT1148784B true IT1148784B (it) 1986-12-03

Family

ID=11179324

Family Applications (1)

Application Number Title Priority Date Filing Date
IT21271/80A IT1148784B (it) 1980-04-09 1980-04-09 Procedimento per la preparazione di microcapsule in un veicolo liquido

Country Status (9)

Country Link
US (1) US4460563A (it)
EP (1) EP0038585B1 (it)
JP (1) JPS56161833A (it)
AT (1) ATE8344T1 (it)
CA (1) CA1162111A (it)
DE (1) DE3164666D1 (it)
DK (1) DK158568C (it)
ES (1) ES501212A0 (it)
IT (1) IT1148784B (it)

Families Citing this family (149)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2470599A1 (fr) * 1979-12-07 1981-06-12 Panoz Donald Perfectionnements apportes aux procedes de preparation de formes galeniques a action retard et a liberation programmee et formes galeniques de medicaments ainsi obtenus
GB8431792D0 (en) * 1984-12-17 1985-01-30 Sandoz Ltd Organic compounds
US4606940A (en) * 1984-12-21 1986-08-19 The Ohio State University Research Foundation Small particle formation and encapsulation
US4777089A (en) * 1985-05-08 1988-10-11 Lion Corporation Microcapsule containing hydrous composition
IT1183574B (it) * 1985-05-08 1987-10-22 Eurand Spa Metodo per ottenere una sospensione estemporanea omogenea di microcapsule
US4908233A (en) * 1985-05-08 1990-03-13 Lion Corporation Production of microcapsules by simple coacervation
SE459005B (sv) * 1985-07-12 1989-05-29 Aake Rikard Lindahl Saett att framstaella sfaeriska polymerpartiklar
IT1214629B (it) * 1985-08-29 1990-01-18 Formenti Farmaceutici Spa Procedimento di microincapsulazione di un medicamento,medicamento cosi'preparato,e composizioni farmaceutiche che lo comprendono
FR2608942B1 (fr) * 1986-12-31 1991-01-11 Centre Nat Rech Scient Procede de preparation de systemes colloidaux dispersibles d'une substance, sous forme de nanocapsules
FI77573C (fi) * 1987-05-08 1989-04-10 Orion Yhtymae Oy Ny konsistens.
US4874667A (en) * 1987-07-20 1989-10-17 Dow Corning Corporation Microencapsulated platinum-group metals and compounds thereof
US4895725A (en) * 1987-08-24 1990-01-23 Clinical Technologies Associates, Inc. Microencapsulation of fish oil
US6056992A (en) * 1988-06-02 2000-05-02 Campbell Soup Company Encapsulated additives
US4916161A (en) * 1988-10-25 1990-04-10 Bristol-Myers Squibb Taste-masking pharmaceutical agents
US5629020A (en) * 1994-04-22 1997-05-13 Emisphere Technologies, Inc. Modified amino acids for drug delivery
US6331318B1 (en) 1994-09-30 2001-12-18 Emisphere Technologies Inc. Carbon-substituted diketopiperazine delivery systems
US6099856A (en) * 1992-06-15 2000-08-08 Emisphere Technologies, Inc. Active agent transport systems
US5693338A (en) * 1994-09-29 1997-12-02 Emisphere Technologies, Inc. Diketopiperazine-based delivery systems
US6221367B1 (en) 1992-06-15 2001-04-24 Emisphere Technologies, Inc. Active agent transport systems
US5714167A (en) * 1992-06-15 1998-02-03 Emisphere Technologies, Inc. Active agent transport systems
US5578323A (en) * 1992-06-15 1996-11-26 Emisphere Technologies, Inc. Proteinoid carriers and methods for preparation and use thereof
US5541155A (en) * 1994-04-22 1996-07-30 Emisphere Technologies, Inc. Acids and acid salts and their use in delivery systems
US5447728A (en) * 1992-06-15 1995-09-05 Emisphere Technologies, Inc. Desferrioxamine oral delivery system
US5443841A (en) * 1992-06-15 1995-08-22 Emisphere Technologies, Inc. Proteinoid microspheres and methods for preparation and use thereof
US5292533A (en) * 1992-03-27 1994-03-08 Micro Flo Co. Controlled release microcapsules
US5281286A (en) * 1992-04-09 1994-01-25 The United States Of America As Represented By The Secretary Of The Army Microcoacervation of propellant ingredients
US5792451A (en) * 1994-03-02 1998-08-11 Emisphere Technologies, Inc. Oral drug delivery compositions and methods
US5811127A (en) * 1992-06-15 1998-09-22 Emisphere Technologies, Inc. Desferrioxamine oral delivery system
US5401516A (en) * 1992-12-21 1995-03-28 Emisphere Technologies, Inc. Modified hydrolyzed vegetable protein microspheres and methods for preparation and use thereof
US5643957A (en) * 1993-04-22 1997-07-01 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US6461643B2 (en) * 1993-04-22 2002-10-08 Emisphere Technologies, Inc. Oral drug delivery compositions and methods
CA2160693C (en) * 1993-04-22 2010-03-16 Sam J. Milstein Oral drug delivery compositions and methods
US5709861A (en) * 1993-04-22 1998-01-20 Emisphere Technologies, Inc. Compositions for the delivery of antigens
US5958457A (en) * 1993-04-22 1999-09-28 Emisphere Technologies, Inc. Compositions for the delivery of antigens
ZA945944B (en) * 1993-08-13 1996-02-08 Eurand America Inc Procedure for encapsulating nsaids
US5650386A (en) * 1995-03-31 1997-07-22 Emisphere Technologies, Inc. Compositions for oral delivery of active agents
US5989539A (en) * 1995-03-31 1999-11-23 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
BR9604880A (pt) * 1995-03-31 1998-05-19 Emisphere Tech Inc Composto composição forma de unidade de dosagem métodos para administração de um agente biologicamente ativo para preparar uma composição para administração de um agente ativo e para preparar um composto e composição farmacológica
US5965121A (en) * 1995-03-31 1999-10-12 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US6090958A (en) * 1995-03-31 2000-07-18 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US6001347A (en) 1995-03-31 1999-12-14 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US5866536A (en) * 1995-03-31 1999-02-02 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US5820881A (en) * 1995-04-28 1998-10-13 Emisphere Technologies, Inc. Microspheres of diamide-dicarboxylic acids
US5750147A (en) * 1995-06-07 1998-05-12 Emisphere Technologies, Inc. Method of solubilizing and encapsulating itraconazole
US6051258A (en) * 1995-06-07 2000-04-18 Emisphere Technologies, Inc. Proteinoid emulsions and methods for preparation and use thereof
US5824345A (en) * 1995-06-07 1998-10-20 Emisphere Technologies, Inc. Fragrances and flavorants
US5667806A (en) * 1995-06-07 1997-09-16 Emisphere Technologies, Inc. Spray drying method and apparatus
US6084112A (en) * 1995-09-11 2000-07-04 Emisphere Technologies, Inc. Method for preparing ω-aminoalkanoic acid derivatives from cycloalkanones
AU2595697A (en) 1996-03-29 1997-10-22 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
AU3828597A (en) 1996-06-14 1998-01-07 Emisphere Technologies, Inc. Microencapsulated fragrances and method for preparation
WO1998014179A1 (en) * 1996-10-01 1998-04-09 Cima Labs Inc. Taste-masked microcapsule compositions and methods of manufacture
US6479082B1 (en) 1996-12-23 2002-11-12 Wm. Wrigley, Jr. Co. Process of increasing flavor release from chewing gum using hydroxypropyl cellulose and product thereof
US6313088B1 (en) 1997-02-07 2001-11-06 Emisphere Technologies, Inc. 8-[(2-hydroxy-4-methoxy benzoyl) amino]-octanoic acid compositions for delivering active agents
US5804688A (en) * 1997-02-07 1998-09-08 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US5939381A (en) * 1997-02-07 1999-08-17 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US5876710A (en) * 1997-02-07 1999-03-02 Emisphere Technologies Inc. Compounds and compositions for delivering active agents
US5879681A (en) * 1997-02-07 1999-03-09 Emisphere Technolgies Inc. Compounds and compositions for delivering active agents
US6060513A (en) * 1997-02-07 2000-05-09 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US5990166A (en) * 1997-02-07 1999-11-23 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US6358504B1 (en) 1997-02-07 2002-03-19 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US5863944A (en) * 1997-04-30 1999-01-26 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US5962710A (en) * 1997-05-09 1999-10-05 Emisphere Technologies, Inc. Method of preparing salicyloylamino acids
PL350925A1 (en) 1999-04-01 2003-02-10 Wrigley W M Jun Co Long flavor duration releasing structures for chewing gum
GB9909369D0 (en) * 1999-04-26 1999-06-16 Eurand Int Method for production of microcapsules
CN1189159C (zh) 2000-05-05 2005-02-16 欧莱雅 含水溶性美容活性组分水性核的微胶囊及含其的组合物
US20030084914A1 (en) * 2001-11-08 2003-05-08 L'oreal Cosmetic articles having encapsulated liquid and method of making same
EP2359817B1 (en) * 2003-03-28 2018-01-10 Sigmoid Pharma Limited Solid oral dosage form containing seamless microcapsules
US7632521B2 (en) * 2003-07-15 2009-12-15 Eurand, Inc. Controlled release potassium chloride tablets
US8486438B2 (en) * 2004-01-29 2013-07-16 Brown University Methods for progenitor cell recruitment and isolation
EP1814530A2 (en) * 2004-09-27 2007-08-08 Sigmoid Biotechnologies Limited Dihydropyrimidine microcapsule-formulations
US7914891B2 (en) 2005-12-28 2011-03-29 Kimberly-Clark Worldwide, Inc. Wipes including microencapsulated delivery vehicles and phase change materials
US20070148459A1 (en) * 2005-12-28 2007-06-28 Kimberly-Clark Worldwide, Inc. Microencapsulated delivery vehicles
US20070145618A1 (en) * 2005-12-28 2007-06-28 Kimberly-Clark Worldwide, Inc. Methods of making microencapsulated delivery vehicles
US7654412B2 (en) 2006-05-30 2010-02-02 Kimberly-Clark Worldwide, Inc. Wet wipe dispensing system for dispensing warm wet wipes
US7497351B2 (en) 2006-05-30 2009-03-03 Kimberly-Clark Worldwide, Inc. Wet wipe dispensing system
WO2008031035A2 (en) * 2006-09-08 2008-03-13 The Regents Of The University Of California Engineering shape of polymeric micro-and nanoparticles
US8192841B2 (en) * 2006-12-14 2012-06-05 Kimberly-Clark Worldwide, Inc. Microencapsulated delivery vehicle having an aqueous core
US7517582B2 (en) * 2006-12-14 2009-04-14 Kimberly-Clark Worldwide, Inc. Supersaturated solutions using crystallization enthalpy to impart temperature change to wet wipes
US7597954B2 (en) * 2006-12-14 2009-10-06 Kimberly-Clark Worldwide, Inc. Supersaturated solutions using crystallization enthalpy to impact temperature change to wet wipes
US20080145437A1 (en) * 2006-12-14 2008-06-19 Kimberly-Clark Worldwide, Inc. Reactive Chemistries For Warming Personal Care Products
ES2524345T3 (es) 2007-04-04 2014-12-05 Sigmoid Pharma Limited Composición farmacéutica oral
ES2963291T3 (es) 2007-04-26 2024-03-26 Sublimity Therapeutics Ltd Fabricación de múltiples minicápsulas
US20080277596A1 (en) * 2007-05-08 2008-11-13 Southwest Research Institute Impact Indicating Microcapsules
WO2008157372A2 (en) 2007-06-14 2008-12-24 Massachusetts Institute Of Technology Self assembled films for protein and drug delivery applications
WO2008157614A2 (en) * 2007-06-21 2008-12-24 Yale University Sustained intraocular delivery of drugs from biodegradable polymeric microparticles
US9822364B2 (en) 2008-03-11 2017-11-21 Yale University Compositions and methods for controlled delivery of inhibitory ribonucleic acids
US9241898B2 (en) * 2008-03-11 2016-01-26 Yale University Compositions and methods for controlled delivery of inhibitory ribonucleic acids
GB0807919D0 (it) * 2008-05-01 2008-06-04 Moorlodge Biotech Ventures Ltd
US20110206773A1 (en) * 2008-05-20 2011-08-25 Yale University Sustained delivery of drugs from biodegradable polymeric microparticles
US9216152B2 (en) 2008-06-27 2015-12-22 Tepha, Inc. Injectable delivery of microparticles and compositions therefore
US9198875B2 (en) * 2008-08-17 2015-12-01 Massachusetts Institute Of Technology Controlled delivery of bioactive agents from decomposable films
EP2471518B1 (en) 2009-05-18 2017-08-23 Sigmoid Pharma Limited Composition comprising oil drops
CN107582526A (zh) 2009-08-12 2018-01-16 希格默伊德药业有限公司 包含聚合物基质和油相的免疫调节组合物
CN101862627B (zh) * 2010-04-29 2012-06-06 上海师范大学 包裹贵金属纳米粒子的二氧化钛微胶囊制备方法
US8673359B2 (en) 2010-07-08 2014-03-18 Brown University Nanoparticle compositions and methods for improved oral delivery of active agents
GB201020032D0 (en) 2010-11-25 2011-01-12 Sigmoid Pharma Ltd Composition
CA2767773C (en) 2011-02-11 2015-11-24 Grain Processing Corporation Composition comprising a salt and a crystallization interrupter
EP2814460B1 (en) 2012-02-17 2018-06-27 Massachusetts Institute Of Technology Glucose-responsive microgels for closed loop insulin delivery
CN104363924B (zh) 2012-03-16 2018-04-17 约翰霍普金斯大学 用于递送hif‑1抑制剂的控制释放调配物
WO2013138346A1 (en) 2012-03-16 2013-09-19 The Johns Hopkins University Non-linear multiblock copolymer-drug conjugates for the delivery of active agents
US10278927B2 (en) 2012-04-23 2019-05-07 Massachusetts Institute Of Technology Stable layer-by-layer coated particles
GB201212010D0 (en) 2012-07-05 2012-08-22 Sigmoid Pharma Ltd Formulations
WO2014134029A1 (en) 2013-02-26 2014-09-04 Massachusetts Institute Of Technology Nucleic acid particles, methods and use thereof
WO2014160404A1 (en) 2013-03-13 2014-10-02 The Regents Of The University Of California Improved oral drug devices and drug formulations
WO2014150074A1 (en) 2013-03-15 2014-09-25 Massachusetts Institute Of Technology Compositions and methods for nucleic acid delivery
KR101486132B1 (ko) 2013-03-20 2015-01-23 씨제이헬스케어 주식회사 졸-겔 변환 특성을 갖는 고분자를 이용한 미립구의 제조방법 및 이로부터 제조된 미립구
GB201319791D0 (en) 2013-11-08 2013-12-25 Sigmoid Pharma Ltd Formulations
CA2936370A1 (en) 2014-01-10 2015-07-16 Chamber Works, Llc A personalizing substance for application to the skin or addition to tattoo ink and methods of preparation thereof
US20150320158A1 (en) 2014-03-14 2015-11-12 Chamber Works, Llc Articles of jewelry containing a personalizing additive such as dna and methods of making
WO2015156922A1 (en) * 2014-04-08 2015-10-15 Dow Global Technologies Llc Dispersion comprising an esterified cellulose ether
PL3721875T3 (pl) 2014-05-09 2024-03-04 Yale University Cząstki pokryte hiperrozgałęzionym poliglicerolem i sposoby ich przygotowania
US11918695B2 (en) 2014-05-09 2024-03-05 Yale University Topical formulation of hyperbranched polymer-coated particles
US10722468B2 (en) 2014-08-14 2020-07-28 Brown University Compositions for stabilizing and delivering proteins
SG11201703553TA (en) 2014-11-07 2017-05-30 Sigmoid Pharma Ltd Compositions comprising cyclosporin
NZ733130A (en) 2014-12-15 2018-09-28 Univ Johns Hopkins Sunitinib formulations and methods for use thereof in treatment of ocular disorders
JP2018503736A (ja) 2015-01-20 2018-02-08 ザ ジョーンズ ホプキンズ ユニバーシティＴｈｅ Ｊｏｈｎｓ Ｈｏｐｋｉｎｓ Ｕｎｉｖｅｒｓｉｔｙ 眼内圧を抑える抗緑内障剤の持続放出のための組成物
US10363226B2 (en) 2015-08-12 2019-07-30 North Carolina State University Platelet membrane-coated drug delivery system
AR106018A1 (es) 2015-08-26 2017-12-06 Achillion Pharmaceuticals Inc Compuestos de arilo, heteroarilo y heterocíclicos para el tratamiento de trastornos médicos
ES2908479T3 (es) 2015-08-26 2022-04-29 Achillion Pharmaceuticals Inc Compuestos para el tratamiento de trastornos inmunitarios e inflamatorios
EP3347794B1 (en) 2015-09-04 2023-07-19 Yale University Polymeric bile acid nanocompositions targeting the pancreas and colon
EP3373978A4 (en) 2015-11-12 2019-06-26 Graybug Vision, Inc. AGGREGATION OF MICROPARTICLES FOR THERAPY
EP3416976A2 (en) 2016-02-16 2018-12-26 Yale University Compositions for enhancing targeted gene editing and methods of use thereof
WO2017143061A1 (en) 2016-02-16 2017-08-24 Yale University Compositions and methods for treatment of cystic fibrosis
US20190022016A1 (en) 2016-03-02 2019-01-24 The Johns Hopkins University Compositions for sustained release of anti-glaucoma agents to control intraocular pressure
CA3029262A1 (en) 2016-06-27 2018-01-04 Achillion Pharmaceuticals, Inc. Quinazoline and indole compounds to treat medical disorders
CA3036693A1 (en) 2016-09-13 2018-03-22 North Carolina State University Platelet compositions and methods for the delivery of therapeutic agents
KR102880704B1 (ko) 2017-03-01 2025-11-04 아칠리온 파르마세우티칼스 인코포레이티드 의학적 장애의 치료를 위한 아릴, 헤테로아릴, 및 헤테로사이클릭 약학적 화합물
WO2018187493A1 (en) 2017-04-04 2018-10-11 Yale University Compositions and methods for in utero delivery
MX2019013363A (es) 2017-05-10 2020-01-13 Graybug Vision Inc Microparticulas de liberacion extendida y suspensiones de las mismas para terapia medica.
WO2019089567A1 (en) 2017-10-30 2019-05-09 Massachusetts Institute Of Technology Layer-by-layer nanoparticles for cytokine therapy in cancer treatment
JP7737226B2 (ja) 2018-02-06 2025-09-10 ソルベンタム インテレクチュアル プロパティズ カンパニー 多孔質又は中空コアとｐＨ感受性シェルとを有するマイクロカプセル及びその使用
US12440536B2 (en) 2018-05-18 2025-10-14 The University Of Hong Kong Compositions of toll-like receptor 5 (TLR5) agonist and methods of use thereof
US20210162013A1 (en) 2018-08-03 2021-06-03 Brown University Compositions and methods for improving the bioavailability of glp1 and analogues thereof
WO2020033951A1 (en) 2018-08-10 2020-02-13 Yale University Compositions and methods for embryonic gene editing in vitro
US20230022157A1 (en) 2018-08-20 2023-01-26 Achillion Pharmaceuticals, Inc. Pharmaceutical compounds for the treatment of complement factor d medical disorders
US11814391B2 (en) 2018-09-06 2023-11-14 Achillion Pharmaceuticals, Inc. Macrocyclic compounds for the treatment of medical disorders
US12018315B2 (en) 2019-05-30 2024-06-25 Massachusetts Institute Of Technology Peptide nucleic acid functionalized hydrogel microneedles for sampling and detection of interstitial fluid nucleic acids
CN115362162A (zh) 2020-02-20 2022-11-18 艾其林医药公司 用于治疗补体因子d介导的障碍的杂芳基化合物
US11007134B1 (en) 2020-03-31 2021-05-18 L'oreal Ceramide containing capsules, ceramide compositions, and cosmetic compositions thereof
WO2021202493A1 (en) 2020-03-31 2021-10-07 L'oreal Ceramide containing capsules, ceramide compositions, and cosmetic compositions thereof
FR3113244B1 (fr) 2020-08-07 2023-03-17 Oreal Capsules contenant du céramide, compositions de céramide, et compositions cosmétiques associées
JP2023532204A (ja) 2020-06-19 2023-07-27 イェール ユニバーシティー 抗原特異的寛容を誘導する免疫調節剤を含むポリマー胆汁酸エステルナノ粒子
WO2022006032A1 (en) 2020-06-30 2022-01-06 L'oreal Cosmetic composition having retinol
FR3113833B1 (fr) 2020-09-08 2023-12-01 Oreal Composition cosmetique contenant du retinol
JP2023542949A (ja) 2020-09-23 2023-10-12 アキリオン ファーマシューティカルズ， インコーポレーテッド 補体媒介性障害の治療のための医薬化合物
WO2022115474A1 (en) 2020-11-27 2022-06-02 General Nanotherapeutics Llc Methods and composition for treatment of immune-mediated diseases
CA3234317A1 (en) 2021-10-22 2023-12-14 Wa Xian Methods and compositions for treating chronic inflammatory injury, metaplasia, dysplasia and cancers of epithelial tissues
CA3267932A1 (en) 2022-10-05 2024-04-11 Mireca Medicines Gmbh MICROPARCEL AND IMPLANT FORMULATIONS FOR ANALOGUE CGMP THERAPY
GB202307563D0 (en) 2023-05-19 2023-07-05 Univ King Abdullah Sci & Tech Methods and compositions

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE530010A (it) * 1953-06-30
US3242051A (en) * 1958-12-22 1966-03-22 Ncr Co Coating by phase separation
US3415758A (en) * 1960-03-09 1968-12-10 Ncr Co Process of forming minute capsules en masse
FR1542807A (fr) * 1967-09-25 1968-10-18 Ncr Co Procédé destiné au séchage de capsules minuscules dont les parois sont en une matière polymère hydrophile
JPS4945130B1 (it) * 1970-08-17 1974-12-02
JPS5214234B2 (it) * 1971-07-30 1977-04-20
BE788762A (fr) * 1971-09-13 1973-01-02 Fuji Photo Film Co Ltd Procede de production de microcapsules
JPS5439346B2 (it) * 1971-09-27 1979-11-27
JPS528795B2 (it) * 1971-12-30 1977-03-11
JPS523342B2 (it) * 1972-01-26 1977-01-27
FR2227332B1 (it) * 1973-04-25 1976-11-12 Cables De Lyon Geoffroy Delore
GB1413186A (en) * 1973-06-27 1975-11-12 Toyo Jozo Kk Process for encapsulation of medicaments
JPS5814253B2 (ja) * 1974-04-10 1983-03-18 カンザキセイシ カブシキガイシヤ ビシヨウカプセルノ セイゾウホウホウ
CA1040018A (en) * 1974-06-19 1978-10-10 Dale R. Shackle Cross-linked hydroxypropylcellulose microcapsules and process for making
JPS5231981A (en) * 1975-08-18 1977-03-10 Takeda Chem Ind Ltd Microcapsule preparation method
JPS55161849A (en) * 1979-06-04 1980-12-16 Toray Silicone Co Ltd Organopolysiloxane composition
US4317743A (en) * 1979-12-05 1982-03-02 Wallace Business Forms, Inc. Process for making microcapsules and resulting product
US4259315A (en) * 1980-06-13 1981-03-31 A. H. Robins Company, Inc. Controlled release potassium dosage form

Also Published As

Publication number Publication date
ES8204613A1 (es) 1982-05-01
IT8021271A0 (it) 1980-04-09
DK158568B (da) 1990-06-11
ES501212A0 (es) 1982-05-01
CA1162111A (en) 1984-02-14
DE3164666D1 (en) 1984-08-16
DK158568C (da) 1990-11-12
US4460563A (en) 1984-07-17
EP0038585A1 (en) 1981-10-28
JPH0411254B2 (it) 1992-02-27
DK160881A (da) 1981-10-10
ATE8344T1 (de) 1984-07-15
JPS56161833A (en) 1981-12-12
EP0038585B1 (en) 1984-07-11

Similar Documents

Publication Publication Date Title
IT1148784B (it) Procedimento per la preparazione di microcapsule in un veicolo liquido
JPS54107881A (en) Preparation of minute capsule
IT1110108B (it) Microcapsule di alcol polivinilico con riempimento liquido,idroinsolubile,e processo per la loro preparazione
NO163060C (no) Fremgangsmaate for fremstilling av substanser som dannes av levende celler som produserer interferoner eller antistoffer.
IT8020489A0 (it) Procedimento per la formazione di elettrodi sulle superficie di membrane semipermeabili e sistemi elettrodo-membrana cosi' prodotti.
ATE66947T1 (de) Verfahren zur herstellung von kleinen, sphaerischen polymerpartikeln.
ES8605983A1 (es) Un metodo de producir una microcapsula de liberacion prolongada de un farmaco soluble en agua
IT8221531A0 (it) Microcapsule di etilcellulosa eprocedimento per prepararle.
NO874989D0 (no) Fremgangsmaate for fremstilling av tabletter eller kapsler som inneholder et super-desintegrasjonsmiddel.
IT7928192A0 (it) Procedimento per la produzione di microcapsule.
EP0332175A3 (en) Method of producing microcapsule
ES2028828T3 (es) Metodo para contener materiales fluidos o solidos utilizando un revestimiento barrera a la presion; metodos para la construccion y prueba de dicho revestimiento.
DE3767113D1 (de) Druckabbausystem fuer den sicherheitsbehaelter eines kernreaktors.
ATE4193T1 (de) Fluessige, kaeltestabile titankatalysatorzubereitung und verfahren zu deren herstellung.
IE36857B1 (en) Process for preparing oil-containing microcapsules
JPS5460281A (en) Apparatus for diffusing substance between two kinds of fluid through semipermeable membrane
NO874355D0 (no) Fremgangsmaate for fremstilling av glycolipid som inneholder n-glycolylneuraminsyre.
IT8467290A1 (it) Procedimento per la produzione di microcapsule, particolarmente per carte da ricalco.
IT7828563A0 (it) Dispositivo per la diffusione e/o filtrazione di sostanze fra due fluidi attraverso membrane semipermeabili.
NO873339D0 (no) Fremgangsmaate til fremstilling av hydrogenperoksyd.
IT1024199B (it) Procedimento per la preparazione di microcapsule di gelatina di contenuto liquido o solido
IT8005116A0 (it) Procedimento per la preparazione di microcapsule.
DK152666C (da) Fremgangsmaade til selektiv fremstilling af 3-chlor eller 3,5-dichlorphenoler ved katalyseret hydrogenering af polychlorphenoler
IT1118818B (it) Procedimento per la preparazione di microcapsule semipermabili
PRAIRIE et al. NRC human-reliability research program

Legal Events

Date Code Title Description
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19990331