ES8204613A1 - Procedimiento de preparacion de microcapsulas en un vehiculoliquido - Google Patents

Procedimiento de preparacion de microcapsulas en un vehiculoliquido

Info

Publication number
ES8204613A1
ES8204613A1 ES501212A ES501212A ES8204613A1 ES 8204613 A1 ES8204613 A1 ES 8204613A1 ES 501212 A ES501212 A ES 501212A ES 501212 A ES501212 A ES 501212A ES 8204613 A1 ES8204613 A1 ES 8204613A1
Authority
ES
Spain
Prior art keywords
liquid vehicle
preparing microcapsules
microcapsules
ionic
preparing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES501212A
Other languages
English (en)
Other versions
ES501212A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Adare Pharmaceuticals SRL
Original Assignee
Eurand International SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eurand International SpA filed Critical Eurand International SpA
Publication of ES8204613A1 publication Critical patent/ES8204613A1/es
Publication of ES501212A0 publication Critical patent/ES501212A0/es
Granted legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
    • Y10T428/2989—Microcapsule with solid core [includes liposome]

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Medicinal Preparation (AREA)
  • Jellies, Jams, And Syrups (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)

Abstract

PROCEDIMIENTO DE PREAPRACION DE MICROCAPSULAS EN UN VEHICULO LIQUIDO. CONSTA DE LAS SIGUIENTES ETAPAS: 1. DISOLUCION DEL POLIMERO QUE CONSTITUYE LA MEMBRANA EN UN DISOLVENTE QUE REPERESENTA EL VEHICULO DE LA MICROENCAPSULACION. 2. ADICION DE LA SUSTANCIA A MICROENCAPSULAR A LA SOLUCION. 3. FORMACION DEL COACERVATO POR ADICION DE UNA SUSTANCIA QUE PROVOQUE LA SEPARACION DE FASE Y/O MODIFICACION DE UNA VARIABLE DEL SISTEMA (YAL COMO PH O TEMPERATURA), QUE DISMINUYA LA SOLUBILIDAD DEL POLIMERO EN EL VEHICULO. 4. DEPOSITO DEL COACERVATO CON FORMACION DE UN RECUBRIMIENTO CONTINUO DE POLIMERO ALREDEDOR DE LOS NUCLEOS DE SUSTANCIA. 5. SOLIDIFICACION DEL POLIMERO.
ES501212A 1980-04-09 1981-04-09 Procedimiento de preparacion de microcapsulas en un vehiculoliquido Granted ES501212A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT21271/80A IT1148784B (it) 1980-04-09 1980-04-09 Procedimento per la preparazione di microcapsule in un veicolo liquido

Publications (2)

Publication Number Publication Date
ES8204613A1 true ES8204613A1 (es) 1982-05-01
ES501212A0 ES501212A0 (es) 1982-05-01

Family

ID=11179324

Family Applications (1)

Application Number Title Priority Date Filing Date
ES501212A Granted ES501212A0 (es) 1980-04-09 1981-04-09 Procedimiento de preparacion de microcapsulas en un vehiculoliquido

Country Status (9)

Country Link
US (1) US4460563A (es)
EP (1) EP0038585B1 (es)
JP (1) JPS56161833A (es)
AT (1) ATE8344T1 (es)
CA (1) CA1162111A (es)
DE (1) DE3164666D1 (es)
DK (1) DK158568C (es)
ES (1) ES501212A0 (es)
IT (1) IT1148784B (es)

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DK158568B (da) 1990-06-11
IT1148784B (it) 1986-12-03
IT8021271A0 (it) 1980-04-09
EP0038585A1 (en) 1981-10-28
JPS56161833A (en) 1981-12-12
ES501212A0 (es) 1982-05-01
EP0038585B1 (en) 1984-07-11
US4460563A (en) 1984-07-17
JPH0411254B2 (es) 1992-02-27
CA1162111A (en) 1984-02-14
DE3164666D1 (en) 1984-08-16
ATE8344T1 (de) 1984-07-15
DK160881A (da) 1981-10-10
DK158568C (da) 1990-11-12

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