SG10201914029RA - Engineered meganucleases specific for recognition sequences in the hepatitis b virus genome - Google Patents

Engineered meganucleases specific for recognition sequences in the hepatitis b virus genome

Info

Publication number
SG10201914029RA
SG10201914029RA SG10201914029RA SG10201914029RA SG10201914029RA SG 10201914029R A SG10201914029R A SG 10201914029RA SG 10201914029R A SG10201914029R A SG 10201914029RA SG 10201914029R A SG10201914029R A SG 10201914029RA SG 10201914029R A SG10201914029R A SG 10201914029RA
Authority
SG
Singapore
Prior art keywords
hepatitis
recognition sequences
virus genome
engineered meganucleases
meganucleases specific
Prior art date
Application number
SG10201914029RA
Other languages
English (en)
Inventor
Derek Jantz
James Smith
Original Assignee
Precision Biosciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Precision Biosciences Inc filed Critical Precision Biosciences Inc
Publication of SG10201914029RA publication Critical patent/SG10201914029RA/en

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    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/22—Ribonucleases RNAses, DNAses
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/465—Hydrolases (3) acting on ester bonds (3.1), e.g. lipases, ribonucleases
    • A—HUMAN NECESSITIES
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P31/12—Antivirals
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
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    • C12N15/09—Recombinant DNA-technology
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    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
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    • C12N2730/00—Reverse transcribing DNA viruses
    • C12N2730/00011—Details
    • C12N2730/10011—Hepadnaviridae
    • C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
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    • C12N2750/14011—Parvoviridae
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    • C12N2750/00011—Details
    • C12N2750/14011—Parvoviridae
    • C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
    • C12N2750/14141—Use of virus, viral particle or viral elements as a vector
    • C12N2750/14143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
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    • C12N2800/00—Nucleic acids vectors
    • C12N2800/10—Plasmid DNA
    • C12N2800/106—Plasmid DNA for vertebrates
    • C12N2800/107—Plasmid DNA for vertebrates for mammalian

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  • Biotechnology (AREA)
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  • Veterinary Medicine (AREA)
  • Virology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
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  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
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  • Communicable Diseases (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Nanotechnology (AREA)
  • Optics & Photonics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
SG10201914029RA 2016-10-14 2017-10-13 Engineered meganucleases specific for recognition sequences in the hepatitis b virus genome SG10201914029RA (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201662408356P 2016-10-14 2016-10-14
US201762452506P 2017-01-31 2017-01-31
US201762527196P 2017-06-30 2017-06-30
US201762527159P 2017-06-30 2017-06-30

Publications (1)

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SG10201914029RA true SG10201914029RA (en) 2020-03-30

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SG10201914029RA SG10201914029RA (en) 2016-10-14 2017-10-13 Engineered meganucleases specific for recognition sequences in the hepatitis b virus genome
SG11201903042VA SG11201903042VA (en) 2016-10-14 2017-10-13 Engineered meganucleases specific for recognition sequences in the hepatitis b virus genome

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US (4) US10662416B2 (es)
EP (2) EP4234691A3 (es)
JP (4) JP6811857B2 (es)
KR (3) KR102305215B1 (es)
CN (2) CN110023495A (es)
AU (2) AU2017342536A1 (es)
BR (1) BR112019007450A2 (es)
CA (1) CA3040143A1 (es)
CL (1) CL2019000993A1 (es)
CO (1) CO2019003675A2 (es)
CR (1) CR20190181A (es)
DK (1) DK3526323T3 (es)
DO (1) DOP2019000097A (es)
FI (1) FI3526323T3 (es)
IL (2) IL265921B2 (es)
MA (1) MA46535A (es)
MX (1) MX2019004349A (es)
PE (1) PE20191353A1 (es)
PH (1) PH12019500788A1 (es)
SG (2) SG10201914029RA (es)
WO (1) WO2018071849A2 (es)

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