PT2859009T - Inibidores macrocíclicos dos vírus flaviviridae - Google Patents
Inibidores macrocíclicos dos vírus flaviviridaeInfo
- Publication number
- PT2859009T PT2859009T PT137304390T PT13730439T PT2859009T PT 2859009 T PT2859009 T PT 2859009T PT 137304390 T PT137304390 T PT 137304390T PT 13730439 T PT13730439 T PT 13730439T PT 2859009 T PT2859009 T PT 2859009T
- Authority
- PT
- Portugal
- Prior art keywords
- flaviviridae viruses
- macrocyclic inhibitors
- macrocyclic
- inhibitors
- flaviviridae
- Prior art date
Links
- 241000710781 Flaviviridae Species 0.000 title 1
- 239000003112 inhibitor Substances 0.000 title 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
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- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/4965—Non-condensed pyrazines
- A61K31/497—Non-condensed pyrazines containing further heterocyclic rings
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- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/50—Pyridazines; Hydrogenated pyridazines
- A61K31/504—Pyridazines; Hydrogenated pyridazines forming part of bridged ring systems
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- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/7056—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing five-membered rings with nitrogen as a ring hetero atom
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- A—HUMAN NECESSITIES
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- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
- A61K31/7072—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid having two oxo groups directly attached to the pyrimidine ring, e.g. uridine, uridylic acid, thymidine, zidovudine
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- C—CHEMISTRY; METALLURGY
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
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- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
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- Oncology (AREA)
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- Mycology (AREA)
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Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201261657553P | 2012-06-08 | 2012-06-08 |
Publications (1)
Publication Number | Publication Date |
---|---|
PT2859009T true PT2859009T (pt) | 2018-01-18 |
Family
ID=48670106
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT137304390T PT2859009T (pt) | 2012-06-08 | 2013-06-07 | Inibidores macrocíclicos dos vírus flaviviridae |
Country Status (21)
Country | Link |
---|---|
US (3) | US9090653B2 (pt) |
EP (1) | EP2859009B1 (pt) |
JP (1) | JP6209600B2 (pt) |
KR (1) | KR20150040266A (pt) |
CN (1) | CN104662033B (pt) |
AU (1) | AU2013271413B2 (pt) |
BR (1) | BR112014030649A2 (pt) |
CA (1) | CA2875718A1 (pt) |
EA (1) | EA201492205A1 (pt) |
ES (1) | ES2656087T3 (pt) |
HK (1) | HK1210483A1 (pt) |
IL (1) | IL236006A0 (pt) |
IN (1) | IN2014MN02658A (pt) |
MX (1) | MX2014014768A (pt) |
NO (1) | NO2887898T3 (pt) |
NZ (2) | NZ724616A (pt) |
PL (1) | PL2859009T3 (pt) |
PT (1) | PT2859009T (pt) |
SG (1) | SG11201408045UA (pt) |
SI (1) | SI2859009T1 (pt) |
WO (1) | WO2013185090A1 (pt) |
Families Citing this family (64)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP6209601B2 (ja) | 2012-06-08 | 2017-10-04 | ギリアード サイエンシーズ, インコーポレイテッド | フラビウイルス科ウイルスの大環状阻害剤 |
PT2859009T (pt) | 2012-06-08 | 2018-01-18 | Gilead Sciences Inc | Inibidores macrocíclicos dos vírus flaviviridae |
AR091279A1 (es) | 2012-06-08 | 2015-01-21 | Gilead Sciences Inc | Inhibidores macrociclicos de virus flaviviridae |
DK3239143T3 (da) * | 2014-12-24 | 2023-04-11 | Lg Chemical Ltd | Biarylderivat som gpr120-agonist |
JP7381190B2 (ja) | 2014-12-26 | 2023-11-15 | エモリー・ユニバーシテイ | N4-ヒドロキシシチジン及び誘導体並びにそれに関連する抗ウイルス用途 |
HUE038059T2 (hu) | 2015-03-04 | 2018-10-29 | Gilead Sciences Inc | Toll-like receptor moduláló 4,6-diamino-pirido[3,2-D]pirimidin vegyületek |
EP3341373A1 (en) | 2015-08-26 | 2018-07-04 | Gilead Sciences, Inc. | Deuterated toll-like receptor modulators |
CN109562107A (zh) | 2016-05-10 | 2019-04-02 | C4医药公司 | 用于靶蛋白降解的杂环降解决定子体 |
WO2017197036A1 (en) | 2016-05-10 | 2017-11-16 | C4 Therapeutics, Inc. | Spirocyclic degronimers for target protein degradation |
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EP2859009B1 (en) | 2017-10-18 |
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JP6209600B2 (ja) | 2017-10-04 |
AU2013271413A1 (en) | 2015-01-22 |
CN104662033A (zh) | 2015-05-27 |
NZ724616A (en) | 2018-06-29 |
US9090653B2 (en) | 2015-07-28 |
US20170190737A1 (en) | 2017-07-06 |
BR112014030649A2 (pt) | 2017-06-27 |
PL2859009T3 (pl) | 2018-03-30 |
CN104662033B (zh) | 2018-10-23 |
US10246486B2 (en) | 2019-04-02 |
HK1210483A1 (en) | 2016-04-22 |
EP2859009A1 (en) | 2015-04-15 |
MX2014014768A (es) | 2015-05-11 |
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