PL2888228T3 - Inhibitory oddziaływania CD40-TRAF6 - Google Patents
Inhibitory oddziaływania CD40-TRAF6Info
- Publication number
- PL2888228T3 PL2888228T3 PL13756096T PL13756096T PL2888228T3 PL 2888228 T3 PL2888228 T3 PL 2888228T3 PL 13756096 T PL13756096 T PL 13756096T PL 13756096 T PL13756096 T PL 13756096T PL 2888228 T3 PL2888228 T3 PL 2888228T3
- Authority
- PL
- Poland
- Prior art keywords
- inhibitors
- traf6 interaction
- traf6
- interaction
- Prior art date
Links
- 239000003112 inhibitor Substances 0.000 title 1
- 230000003993 interaction Effects 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
- A61K31/381—Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
- A61K31/341—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide not condensed with another ring, e.g. ranitidine, furosemide, bufetolol, muscarine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C251/00—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton
- C07C251/02—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton containing imino groups
- C07C251/24—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton containing imino groups having carbon atoms of imino groups bound to carbon atoms of six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C251/00—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton
- C07C251/02—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton containing imino groups
- C07C251/26—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton containing imino groups having nitrogen atoms of imino groups further bound to halogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D307/52—Radicals substituted by nitrogen atoms not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/22—Radicals substituted by doubly bound hetero atoms, or by two hetero atoms other than halogen singly bound to the same carbon atom
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Emergency Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Dermatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP12181862.9A EP2703384A1 (en) | 2012-08-27 | 2012-08-27 | Inhibitors of CD40-TRAF6 interaction |
| EP13756096.7A EP2888228B1 (en) | 2012-08-27 | 2013-08-27 | Inhibitors of cd40-traf6 interaction |
| PCT/EP2013/067714 WO2014033122A1 (en) | 2012-08-27 | 2013-08-27 | Inhibitors of cd40-traf6 interaction |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL2888228T3 true PL2888228T3 (pl) | 2019-10-31 |
Family
ID=46754331
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL13756096T PL2888228T3 (pl) | 2012-08-27 | 2013-08-27 | Inhibitory oddziaływania CD40-TRAF6 |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US9408829B2 (pl) |
| EP (2) | EP2703384A1 (pl) |
| AU (1) | AU2013307369B2 (pl) |
| CA (1) | CA2880374A1 (pl) |
| DK (1) | DK2888228T3 (pl) |
| ES (1) | ES2734286T3 (pl) |
| PL (1) | PL2888228T3 (pl) |
| WO (1) | WO2014033122A1 (pl) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA3021645A1 (en) | 2016-04-29 | 2017-11-02 | Icahn School Of Medicine At Mount Sinai | Targeting the innate immune system to induce long-term tolerance and to resolve macrophage accumulation in atherosclerosis |
| US10822299B2 (en) | 2016-05-26 | 2020-11-03 | The Regents Of The University Of California | Compounds and methods for hematopoietic regeneration |
| CA3084491A1 (en) * | 2017-11-29 | 2019-06-06 | The Regents Of The University Of California | Compounds and methods for hematopoietic regeneration |
| AU2022239614A1 (en) | 2021-03-19 | 2023-10-12 | Icahn School Of Medicine At Mount Sinai | Compounds for regulating trained immunity, and their methods of use |
| WO2023108488A1 (zh) * | 2021-12-15 | 2023-06-22 | 深圳先进技术研究院 | 一种筛选抑制foxp3小分子药物的方法 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8642660B2 (en) * | 2007-12-21 | 2014-02-04 | The University Of Rochester | Method for altering the lifespan of eukaryotic organisms |
| WO2009143141A1 (en) * | 2008-05-19 | 2009-11-26 | Case Western Reserve University | Method for treating cd40-mediated diseases |
| US9095596B2 (en) * | 2009-10-15 | 2015-08-04 | Southern Research Institute | Treatment of neurodegenerative diseases, causation of memory enhancement, and assay for screening compounds for such |
-
2012
- 2012-08-27 EP EP12181862.9A patent/EP2703384A1/en not_active Withdrawn
-
2013
- 2013-08-27 ES ES13756096T patent/ES2734286T3/es active Active
- 2013-08-27 WO PCT/EP2013/067714 patent/WO2014033122A1/en not_active Ceased
- 2013-08-27 PL PL13756096T patent/PL2888228T3/pl unknown
- 2013-08-27 US US14/417,708 patent/US9408829B2/en not_active Expired - Fee Related
- 2013-08-27 EP EP13756096.7A patent/EP2888228B1/en not_active Not-in-force
- 2013-08-27 AU AU2013307369A patent/AU2013307369B2/en not_active Ceased
- 2013-08-27 CA CA2880374A patent/CA2880374A1/en not_active Abandoned
- 2013-08-27 DK DK13756096.7T patent/DK2888228T3/da active
-
2016
- 2016-02-09 US US15/019,581 patent/US9750717B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP2888228B1 (en) | 2019-04-24 |
| US9750717B2 (en) | 2017-09-05 |
| AU2013307369B2 (en) | 2018-01-04 |
| AU2013307369A1 (en) | 2015-02-19 |
| CA2880374A1 (en) | 2014-03-06 |
| DK2888228T3 (da) | 2019-07-15 |
| EP2888228A1 (en) | 2015-07-01 |
| US20150190370A1 (en) | 2015-07-09 |
| ES2734286T3 (es) | 2019-12-05 |
| US9408829B2 (en) | 2016-08-09 |
| EP2703384A1 (en) | 2014-03-05 |
| WO2014033122A1 (en) | 2014-03-06 |
| US20160228408A1 (en) | 2016-08-11 |
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