SE510666C2 - Nya Kristallmodifikationer - Google Patents

Nya Kristallmodifikationer

Info

Publication number
SE510666C2
SE510666C2 SE9604793A SE9604793A SE510666C2 SE 510666 C2 SE510666 C2 SE 510666C2 SE 9604793 A SE9604793 A SE 9604793A SE 9604793 A SE9604793 A SE 9604793A SE 510666 C2 SE510666 C2 SE 510666C2
Authority
SE
Sweden
Prior art keywords
omeprazole
neutral
solution
solvent
water
Prior art date
Application number
SE9604793A
Other languages
English (en)
Swedish (sv)
Other versions
SE9604793D0 (sv
SE9604793L (sv
Inventor
Martin Bohlin
Karol Horvath
Sverker Von Unge
Original Assignee
Astra Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=20405146&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SE510666(C2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Astra Ab filed Critical Astra Ab
Priority to SE9604793A priority Critical patent/SE510666C2/sv
Publication of SE9604793D0 publication Critical patent/SE9604793D0/xx
Priority to TW086118449A priority patent/TW538039B/zh
Priority to ZA9711046A priority patent/ZA9711046B/xx
Priority to TR1999/01410T priority patent/TR199901410T2/xx
Priority to SK765-99A priority patent/SK285151B6/sk
Priority to KR1019997005574A priority patent/KR20000069595A/ko
Priority to IL13045097A priority patent/IL130450A0/xx
Priority to RU99116303/04A priority patent/RU2184734C2/ru
Priority to ES97951367T priority patent/ES2194231T3/es
Priority to YUP-281/99A priority patent/RS49685B/sr
Priority to AU55026/98A priority patent/AU730129B2/en
Priority to PT97951367T priority patent/PT946547E/pt
Priority to BR9714059-7A priority patent/BR9714059A/pt
Priority to EP97951367A priority patent/EP0946547B1/de
Priority to CA002274076A priority patent/CA2274076C/en
Priority to NZ336024A priority patent/NZ336024A/en
Priority to CN97180849A priority patent/CN1109684C/zh
Priority to SI9730528T priority patent/SI0946547T1/xx
Priority to UA99073869A priority patent/UA55436C2/uk
Priority to ARP970105920A priority patent/AR010361A1/es
Priority to AT97951367T priority patent/ATE236898T1/de
Priority to DK97951367T priority patent/DK0946547T3/da
Priority to IDW990483A priority patent/ID21850A/id
Priority to US09/000,154 priority patent/US6162816A/en
Priority to HU0001547A priority patent/HU227589B1/hu
Priority to PCT/SE1997/002125 priority patent/WO1998028294A1/en
Priority to CZ19992202A priority patent/CZ294784B6/cs
Priority to DE69720774T priority patent/DE69720774T2/de
Priority to JP52868598A priority patent/JP4402174B2/ja
Priority to EEP199900259A priority patent/EE03923B1/xx
Priority to PL97334297A priority patent/PL190377B1/pl
Priority to MYPI97006176A priority patent/MY117032A/en
Priority to EG136097A priority patent/EG24414A/xx
Priority to SA97180739A priority patent/SA97180739B1/ar
Publication of SE9604793L publication Critical patent/SE9604793L/xx
Priority to IS5070A priority patent/IS1981B/is
Publication of SE510666C2 publication Critical patent/SE510666C2/sv
Priority to NO19993068A priority patent/NO317191B1/no
Priority to HK00101986A priority patent/HK1022909A1/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/06Antipsoriatics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
SE9604793A 1996-12-20 1996-12-20 Nya Kristallmodifikationer SE510666C2 (sv)

Priority Applications (37)

Application Number Priority Date Filing Date Title
SE9604793A SE510666C2 (sv) 1996-12-20 1996-12-20 Nya Kristallmodifikationer
TW086118449A TW538039B (en) 1996-12-20 1997-12-08 Neutral S-omeprazole in a form or b form, process for preparing the same, and pharmaceutical composition comprising the same
ZA9711046A ZA9711046B (en) 1996-12-20 1997-12-09 A novel compound form.
EEP199900259A EE03923B1 (et) 1996-12-20 1997-12-16 S-omeprasool neutraalsel kujul, selle valmistamise protsess ja seda sisaldavad ravimsegud
PL97334297A PL190377B1 (pl) 1996-12-20 1997-12-16 S-Omeprazol w postaci obojętnej, sposób wytwarzania S-omeprazolu, środek farmaceutyczny i zastosowanie S-omeprazolu
SI9730528T SI0946547T1 (en) 1996-12-20 1997-12-16 A novel compound form
AT97951367T ATE236898T1 (de) 1996-12-20 1997-12-16 S-omeprazol in festform
KR1019997005574A KR20000069595A (ko) 1996-12-20 1997-12-16 신규한 형태의 화합물
IL13045097A IL130450A0 (en) 1996-12-20 1997-12-16 A novel compound form
RU99116303/04A RU2184734C2 (ru) 1996-12-20 1997-12-16 S-омепразол в нейтральной форме, способы его получения, фармацевтическая композиция, содержащая s-омепразол в нейтральной форме, и способ лечения связанного с желудочной кислотой состояния
ES97951367T ES2194231T3 (es) 1996-12-20 1997-12-16 Una nueva forma de compuesto.
YUP-281/99A RS49685B (sr) 1996-12-20 1997-12-16 Novi oblik jedinjenja
AU55026/98A AU730129B2 (en) 1996-12-20 1997-12-16 A novel compound form
PT97951367T PT946547E (pt) 1996-12-20 1997-12-16 Nova forma de composto
BR9714059-7A BR9714059A (pt) 1996-12-20 1997-12-16 S-omeprazol em uma forma neutra, processo para preparar o mesmo, uso deste, composição farmacêutica, e, processo para tratar uma condição relacionada com ácido gástrico.
EP97951367A EP0946547B1 (de) 1996-12-20 1997-12-16 S-omeprazol in festform
CA002274076A CA2274076C (en) 1996-12-20 1997-12-16 Crystalline form of s-omeprazole
NZ336024A NZ336024A (en) 1996-12-20 1997-12-16 Neutral crystalline S-omeprazole
CN97180849A CN1109684C (zh) 1996-12-20 1997-12-16 新的化合物形态
TR1999/01410T TR199901410T2 (xx) 1996-12-20 1997-12-16 Yeni bir bile�im bi�imi.
UA99073869A UA55436C2 (uk) 1996-12-20 1997-12-16 Нова форма s-омепразолу, спосіб його одержання, фармацевтична композиція та використання у виробництві лікувального засобу
ARP970105920A AR010361A1 (es) 1996-12-20 1997-12-16 "S-OMEPRAZOL [ENANTIoMERO S DE 5-METOXI-2-[[(4--METOXI-3,5-DIMETIL-2-PIRIDINIL)-METIL]SULFINIL]-1H-BENCIMIDAZOL], EN UNA FORMA NEUTRA NO SALINA, PROCESO PARA SU PREPARACION, COMPOSICION FARMACEUTICA, Y SU USO PARA LA MANUFACTURA DE MEDICAMENTOS"
SK765-99A SK285151B6 (sk) 1996-12-20 1997-12-16 Neutrálna forma S-enantioméru omeprazolu, spôsob jeho prípravy, farmaceutická kompozícia s jeho obsahom a jeho použitie
DK97951367T DK0946547T3 (da) 1996-12-20 1997-12-16 Hidtil ukendt forbindelsesform
IDW990483A ID21850A (id) 1996-12-20 1997-12-16 Formula senyawa baru
US09/000,154 US6162816A (en) 1996-12-20 1997-12-16 Crystalline form of the S-enantiomer of omeprazole
HU0001547A HU227589B1 (en) 1996-12-20 1997-12-16 Crystal form of (s)-omeprazole
PCT/SE1997/002125 WO1998028294A1 (en) 1996-12-20 1997-12-16 A novel compound form
CZ19992202A CZ294784B6 (cs) 1996-12-20 1997-12-16 Nová forma S-omeprazolu
DE69720774T DE69720774T2 (de) 1996-12-20 1997-12-16 S-omeprazol in festform
JP52868598A JP4402174B2 (ja) 1996-12-20 1997-12-16 新規な化合物形態
MYPI97006176A MY117032A (en) 1996-12-20 1997-12-19 A novel compound form.
EG136097A EG24414A (en) 1996-12-20 1997-12-20 A novel compound form
SA97180739A SA97180739B1 (ar) 1996-12-20 1997-12-27 الشكل البللوري للمتشاكل S - enantiomer للأومبرازول omeprazole
IS5070A IS1981B (is) 1996-12-20 1999-06-07 Nýtt form S-handhverfu ómeprasóls og lyfjablöndursem innihalda það
NO19993068A NO317191B1 (no) 1996-12-20 1999-06-21 S-omeprazol i noytral form, fremgangsmate for fremstilling derav, farmasoytisk preparat inneholdende en slik form, og anvendelse derav
HK00101986A HK1022909A1 (en) 1996-12-20 2000-03-31 A novel compound form

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9604793A SE510666C2 (sv) 1996-12-20 1996-12-20 Nya Kristallmodifikationer

Publications (3)

Publication Number Publication Date
SE9604793D0 SE9604793D0 (sv) 1996-12-20
SE9604793L SE9604793L (sv) 1998-06-21
SE510666C2 true SE510666C2 (sv) 1999-06-14

Family

ID=20405146

Family Applications (1)

Application Number Title Priority Date Filing Date
SE9604793A SE510666C2 (sv) 1996-12-20 1996-12-20 Nya Kristallmodifikationer

Country Status (37)

Country Link
US (1) US6162816A (de)
EP (1) EP0946547B1 (de)
JP (1) JP4402174B2 (de)
KR (1) KR20000069595A (de)
CN (1) CN1109684C (de)
AR (1) AR010361A1 (de)
AT (1) ATE236898T1 (de)
AU (1) AU730129B2 (de)
BR (1) BR9714059A (de)
CA (1) CA2274076C (de)
CZ (1) CZ294784B6 (de)
DE (1) DE69720774T2 (de)
DK (1) DK0946547T3 (de)
EE (1) EE03923B1 (de)
EG (1) EG24414A (de)
ES (1) ES2194231T3 (de)
HK (1) HK1022909A1 (de)
HU (1) HU227589B1 (de)
ID (1) ID21850A (de)
IL (1) IL130450A0 (de)
IS (1) IS1981B (de)
MY (1) MY117032A (de)
NO (1) NO317191B1 (de)
NZ (1) NZ336024A (de)
PL (1) PL190377B1 (de)
PT (1) PT946547E (de)
RS (1) RS49685B (de)
RU (1) RU2184734C2 (de)
SA (1) SA97180739B1 (de)
SE (1) SE510666C2 (de)
SI (1) SI0946547T1 (de)
SK (1) SK285151B6 (de)
TR (1) TR199901410T2 (de)
TW (1) TW538039B (de)
UA (1) UA55436C2 (de)
WO (1) WO1998028294A1 (de)
ZA (1) ZA9711046B (de)

Families Citing this family (60)

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US6645988B2 (en) 1996-01-04 2003-11-11 Curators Of The University Of Missouri Substituted benzimidazole dosage forms and method of using same
US5840737A (en) 1996-01-04 1998-11-24 The Curators Of The University Of Missouri Omeprazole solution and method for using same
US6489346B1 (en) 1996-01-04 2002-12-03 The Curators Of The University Of Missouri Substituted benzimidazole dosage forms and method of using same
US6699885B2 (en) 1996-01-04 2004-03-02 The Curators Of The University Of Missouri Substituted benzimidazole dosage forms and methods of using same
SI20019A (sl) 1998-07-13 2000-02-29 LEK, tovarna farmacevtskih in kemi�nih izdelkov, d.d. Izboljšan postopek sinteze 5-metoksi -2-/(4-metoksi-3,5-dimetil-2-piridil)metil/ sulfinil-1H-benzimidazola
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IL142703A (en) 1998-11-10 2006-04-10 Astrazeneca Ab Crystalline form of omeprazole
JP3926936B2 (ja) 1998-11-16 2007-06-06 エーザイ・アール・アンド・ディー・マネジメント株式会社 スルホキシド誘導体・アセトン錯体およびその製造法
SE9804003D0 (sv) * 1998-11-23 1998-11-23 Astra Ab A method of producing drug particles
SE9900274D0 (sv) 1999-01-28 1999-01-28 Astra Ab New compound
JP2000344739A (ja) * 1999-06-01 2000-12-12 Sumitomo Chem Co Ltd N−保護−アゼチジン−2−カルボン酸の製造方法
TWI289557B (en) 1999-06-17 2007-11-11 Takeda Chemical Industries Ltd A crystal of a hydrate of (R)-2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridyl]methyl]sulfinyl]-1H-benzimidazole
SE0000774D0 (sv) 2000-03-08 2000-03-08 Astrazeneca Ab New formulation
SE0000773D0 (sv) * 2000-03-08 2000-03-08 Astrazeneca Ab New formulation
DE60131649T2 (de) 2000-05-15 2008-10-30 Takeda Pharmaceutical Co. Ltd. Verfahren zur herstellung eines kristalls
GB0016040D0 (en) * 2000-06-29 2000-08-23 Glaxo Group Ltd Novel process for preparing crystalline particles
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SI20875A (sl) * 2001-04-25 2002-10-31 LEK, tovarna farmacevtskih in kemi�nih izdelkov, d.d. Kristalna oblika omeprazola
US8206741B2 (en) 2001-06-01 2012-06-26 Pozen Inc. Pharmaceutical compositions for the coordinated delivery of NSAIDs
ATE474559T1 (de) 2001-06-01 2010-08-15 Pozen Inc Pharmazeutische zusammensetzungen für die koordinierte abgabe von nsaid
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SE0102993D0 (sv) 2001-09-07 2001-09-07 Astrazeneca Ab New self emulsifying drug delivery system
WO2004002982A2 (en) * 2002-06-27 2004-01-08 Dr. Reddy's Laboratories Limited A process for preparation of optically pure or optically enriched sulfoxide compounds, including amorphous esomeprazole and salts thereof
ATE353887T1 (de) * 2002-06-27 2007-03-15 Reddys Lab Ltd Dr Verfahren zur herstellung optisch reiner oder optisch angereicherter sulfoxidverbindungen einschliesslich amorphen esomeprazols und dessen salze
CA2501424A1 (en) * 2002-08-30 2004-03-11 Dr. Reddy's Laboratories Limited Amorphous hydrates of esomeprazole magnesium and process for the preparation thereof
CA2771725C (en) 2002-10-16 2015-08-18 Takeda Pharmaceutical Company Limited Solid preparation comprising a non-toxic base and a proton pump inhibitor
EA200500673A1 (ru) * 2002-10-22 2005-12-29 Рэнбакси Лабораториз Лимитед Аморфная форма соли эзомепразола, способ ее получения и фармацевтическая композиция на её основе
US20040242642A1 (en) * 2002-11-18 2004-12-02 Dr. Reddy's Laboratories Limited Crystalline esomeprazole compounds and process for the preparation thereof
US20060247277A1 (en) * 2003-02-28 2006-11-02 Yatendra Kumar Polymorphs of s-omeprazole
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EP2195309A4 (de) 2007-10-08 2013-04-24 Hetero Drugs Ltd Polymorphe von esomeprazolsalzen
EA017064B1 (ru) 2008-03-10 2012-09-28 Такеда Фармасьютикал Компани Лимитед Кристаллическое производное бензимидазола
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SI2510089T1 (sl) 2009-12-08 2015-12-31 Codexis, Inc. Sinteza prazolnih spojin
EP2649187B1 (de) 2010-12-08 2017-11-22 Codexis, Inc. Biokatalysatoren und verfahren zur synthese von armodafinil
WO2013101897A2 (en) 2011-12-28 2013-07-04 Pozen Inc. Improved compositions and methods for delivery of omeprazole plus acetylsalicylic acid
RU2501549C1 (ru) 2012-08-30 2013-12-20 Авва Девелопмент Лтд Фармацевтическая композиция для лечения гастроэзофагеальной рефлюксной болезни
CN107043367A (zh) * 2017-05-26 2017-08-15 重庆莱美隆宇药业有限公司 一种中性s‑奥美拉唑的干燥工艺
WO2024075017A1 (en) 2022-10-04 2024-04-11 Zabirnyk Arsenii Inhibition of aortic valve calcification

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Also Published As

Publication number Publication date
TR199901410T2 (xx) 1999-08-23
ATE236898T1 (de) 2003-04-15
YU28199A (sh) 2002-03-18
ZA9711046B (en) 1998-06-22
HU227589B1 (en) 2011-09-28
HUP0001547A2 (hu) 2002-05-29
CN1109684C (zh) 2003-05-28
DK0946547T3 (da) 2003-06-30
SE9604793D0 (sv) 1996-12-20
IL130450A0 (en) 2000-06-01
RU2184734C2 (ru) 2002-07-10
EE03923B1 (et) 2002-12-16
ID21850A (id) 1999-08-05
EP0946547A1 (de) 1999-10-06
RS49685B (sr) 2007-11-15
EP0946547B1 (de) 2003-04-09
CA2274076A1 (en) 1998-07-02
NO317191B1 (no) 2004-09-13
AU5502698A (en) 1998-07-17
HU0001547D0 (de) 2002-05-29
PT946547E (pt) 2003-07-31
WO1998028294A1 (en) 1998-07-02
EG24414A (en) 2009-05-25
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TW538039B (en) 2003-06-21
UA55436C2 (uk) 2003-04-15
HUP0001547A3 (en) 2002-06-28
CZ294784B6 (cs) 2005-03-16
CZ220299A3 (cs) 2000-02-16
AU730129B2 (en) 2001-02-22
JP2001507025A (ja) 2001-05-29
CN1241183A (zh) 2000-01-12
PL334297A1 (en) 2000-02-14
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SK285151B6 (sk) 2006-07-07
SK76599A3 (en) 1999-12-10
KR20000069595A (ko) 2000-11-25
IS1981B (is) 2005-01-14
JP4402174B2 (ja) 2010-01-20
MY117032A (en) 2004-04-30
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PL190377B1 (pl) 2005-12-30
NO993068L (no) 1999-06-21
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SA97180739B1 (ar) 2006-05-20
US6162816A (en) 2000-12-19
BR9714059A (pt) 2000-05-09
SI0946547T1 (en) 2003-10-31
NO993068D0 (no) 1999-06-21
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NZ336024A (en) 2001-02-23
IS5070A (is) 1999-06-07

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