IS1981B - Nýtt form S-handhverfu ómeprasóls og lyfjablöndursem innihalda það - Google Patents

Nýtt form S-handhverfu ómeprasóls og lyfjablöndursem innihalda það

Info

Publication number
IS1981B
IS1981B IS5070A IS5070A IS1981B IS 1981 B IS1981 B IS 1981B IS 5070 A IS5070 A IS 5070A IS 5070 A IS5070 A IS 5070A IS 1981 B IS1981 B IS 1981B
Authority
IS
Iceland
Prior art keywords
omeprazole
enantiomer
pharmaceutical preparation
preparation containing
new form
Prior art date
Application number
IS5070A
Other languages
English (en)
Other versions
IS5070A (is
Inventor
Bohlin Martin
Horvath Karol
Von Unge Sverker
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=20405146&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IS1981(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of IS5070A publication Critical patent/IS5070A/is
Publication of IS1981B publication Critical patent/IS1981B/is

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/06Antipsoriatics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IS5070A 1996-12-20 1999-06-07 Nýtt form S-handhverfu ómeprasóls og lyfjablöndursem innihalda það IS1981B (is)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9604793A SE510666C2 (sv) 1996-12-20 1996-12-20 Nya Kristallmodifikationer
PCT/SE1997/002125 WO1998028294A1 (en) 1996-12-20 1997-12-16 A novel compound form

Publications (2)

Publication Number Publication Date
IS5070A IS5070A (is) 1999-06-07
IS1981B true IS1981B (is) 2005-01-14

Family

ID=20405146

Family Applications (1)

Application Number Title Priority Date Filing Date
IS5070A IS1981B (is) 1996-12-20 1999-06-07 Nýtt form S-handhverfu ómeprasóls og lyfjablöndursem innihalda það

Country Status (36)

Country Link
US (1) US6162816A (is)
EP (1) EP0946547B1 (is)
JP (1) JP4402174B2 (is)
KR (1) KR20000069595A (is)
CN (1) CN1109684C (is)
AR (1) AR010361A1 (is)
AT (1) ATE236898T1 (is)
AU (1) AU730129B2 (is)
BR (1) BR9714059A (is)
CA (1) CA2274076C (is)
CZ (1) CZ294784B6 (is)
DE (1) DE69720774T2 (is)
DK (1) DK0946547T3 (is)
EE (1) EE03923B1 (is)
EG (1) EG24414A (is)
ES (1) ES2194231T3 (is)
HU (1) HU227589B1 (is)
ID (1) ID21850A (is)
IL (1) IL130450A0 (is)
IS (1) IS1981B (is)
MY (1) MY117032A (is)
NO (1) NO317191B1 (is)
NZ (1) NZ336024A (is)
PL (1) PL190377B1 (is)
PT (1) PT946547E (is)
RS (1) RS49685B (is)
RU (1) RU2184734C2 (is)
SA (1) SA97180739B1 (is)
SE (1) SE510666C2 (is)
SI (1) SI0946547T1 (is)
SK (1) SK285151B6 (is)
TR (1) TR199901410T2 (is)
TW (1) TW538039B (is)
UA (1) UA55436C2 (is)
WO (1) WO1998028294A1 (is)
ZA (1) ZA9711046B (is)

Families Citing this family (60)

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US6645988B2 (en) 1996-01-04 2003-11-11 Curators Of The University Of Missouri Substituted benzimidazole dosage forms and method of using same
US6489346B1 (en) 1996-01-04 2002-12-03 The Curators Of The University Of Missouri Substituted benzimidazole dosage forms and method of using same
US5840737A (en) 1996-01-04 1998-11-24 The Curators Of The University Of Missouri Omeprazole solution and method for using same
US6699885B2 (en) 1996-01-04 2004-03-02 The Curators Of The University Of Missouri Substituted benzimidazole dosage forms and methods of using same
SI20019A (sl) 1998-07-13 2000-02-29 LEK, tovarna farmacevtskih in kemi�nih izdelkov, d.d. Izboljšan postopek sinteze 5-metoksi -2-/(4-metoksi-3,5-dimetil-2-piridil)metil/ sulfinil-1H-benzimidazola
UA72748C2 (en) * 1998-11-10 2005-04-15 Astrazeneca Ab A novel crystalline form of omeprazole
IL142703A (en) 1998-11-10 2006-04-10 Astrazeneca Ab Crystalline form of omeprazole
JP3926936B2 (ja) 1998-11-16 2007-06-06 エーザイ・アール・アンド・ディー・マネジメント株式会社 スルホキシド誘導体・アセトン錯体およびその製造法
SE9804003D0 (sv) * 1998-11-23 1998-11-23 Astra Ab A method of producing drug particles
SE9900274D0 (sv) * 1999-01-28 1999-01-28 Astra Ab New compound
JP2000344739A (ja) * 1999-06-01 2000-12-12 Sumitomo Chem Co Ltd N−保護−アゼチジン−2−カルボン酸の製造方法
TWI275587B (en) 1999-06-17 2007-03-11 Takeda Chemical Industries Ltd A crystal of (R)-2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridyl]methyl]sulfinyl]-1H-benzimidazole
SE0000773D0 (sv) * 2000-03-08 2000-03-08 Astrazeneca Ab New formulation
SE0000774D0 (sv) 2000-03-08 2000-03-08 Astrazeneca Ab New formulation
EP2281821B1 (en) * 2000-05-15 2014-10-22 Takeda Pharmaceutical Company Limited Process for producing a crystal of (R)-2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridyl]methyl]sulfinyl]benzimidazole
GB0016040D0 (en) * 2000-06-29 2000-08-23 Glaxo Group Ltd Novel process for preparing crystalline particles
CA2775616C (en) 2000-08-04 2013-09-17 Takeda Pharmaceutical Company Limited Salts of benzimidazole compound and application thereof
SI20875A (sl) * 2001-04-25 2002-10-31 LEK, tovarna farmacevtskih in kemi�nih izdelkov, d.d. Kristalna oblika omeprazola
US8206741B2 (en) 2001-06-01 2012-06-26 Pozen Inc. Pharmaceutical compositions for the coordinated delivery of NSAIDs
US6926907B2 (en) 2001-06-01 2005-08-09 Pozen Inc. Pharmaceutical compositions for the coordinated delivery of NSAIDs
GB2376231A (en) 2001-06-06 2002-12-11 Cipla Ltd Benzimidazole-cyclodextrin inclusion complex
SE0102993D0 (sv) 2001-09-07 2001-09-07 Astrazeneca Ab New self emulsifying drug delivery system
CN100378093C (zh) * 2002-06-27 2008-04-02 雷迪实验室有限公司 一种制备包括无定形艾美拉唑及其盐在内的光学纯或光学浓缩的亚砜化合物的方法
US7169793B2 (en) 2002-06-27 2007-01-30 Dr. Reddy's Laboratories Limited Process for preparation of optically pure or optically enriched sulfoxide compounds, including amorphous esomeprazole and salts thereof
EP1546131A1 (en) * 2002-08-30 2005-06-29 Dr. Reddy's Laboratories Ltd. Amorphous hydrates of esomeprazole magnesium and process for the preparation thereof
CA2771725C (en) 2002-10-16 2015-08-18 Takeda Pharmaceutical Company Limited Solid preparation comprising a non-toxic base and a proton pump inhibitor
CN1728997A (zh) * 2002-10-22 2006-02-01 兰贝克赛实验室有限公司 (es)奥美拉唑的无定形盐
US20040242642A1 (en) * 2002-11-18 2004-12-02 Dr. Reddy's Laboratories Limited Crystalline esomeprazole compounds and process for the preparation thereof
US20060247277A1 (en) * 2003-02-28 2006-11-02 Yatendra Kumar Polymorphs of s-omeprazole
CN100364987C (zh) * 2003-03-24 2008-01-30 卫材R&D管理有限公司 亚砜衍生物或其盐的非定形态的制备方法
CN1842525A (zh) * 2003-05-05 2006-10-04 兰贝克赛实验室有限公司 苯并咪唑衍生物的钡盐
US8993599B2 (en) 2003-07-18 2015-03-31 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
SE0400410D0 (sv) 2004-02-20 2004-02-20 Astrazeneca Ab New compounds
US8906940B2 (en) 2004-05-25 2014-12-09 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
US8815916B2 (en) 2004-05-25 2014-08-26 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
AU2005264864B2 (en) 2004-06-16 2011-08-11 Takeda Pharmaceutical Company Limited Multiple PPI dosage form
CA2570795C (en) 2004-06-24 2013-05-28 Astrazeneca Ab Process for the preparation of crystal modifications for use in the preparation of esomeprazole sodium salt
ES2246149B1 (es) * 2004-07-02 2007-06-01 Esteve Quimica, S.A. Formas solidas de la sal magnesica de s-omeprazol y procedimientos para su preparacion.
EP1885711A1 (en) * 2005-05-06 2008-02-13 Glenmark Pharmaceuticals Limited Esomeprazole strontium salt, process for its preparation and pharmaceutical compositions containing same
US8247566B2 (en) * 2005-06-08 2012-08-21 Lek Pharmaceuticals D.D. Crystalline solvate of omeprazole sodium
WO2006134605A1 (en) 2005-06-15 2006-12-21 Hetero Drugs Limited Amorphous esomeprazole hydrate
NL2000126C2 (nl) * 2005-07-15 2008-01-29 Solvay Werkwijze voor de vervaardiging van eptifibatide.
US20070043085A1 (en) * 2005-08-19 2007-02-22 Glenmark Pharmaceuticals Limited Process for the preparation of amorphous form of neutral esomeprazole
US7576219B2 (en) 2005-10-26 2009-08-18 Hanmi Pharm. Co., Ltd Crystalline S-omeprazole strontium hydrate, method for preparing same, and pharmaceutical composition containing same
US20090082572A1 (en) * 2005-11-14 2009-03-26 Hetero Drugs Limited Process for amorphous esomeprazole
EP1960384A4 (en) * 2005-12-05 2010-03-24 Astrazeneca Ab NOVEL PROCESS FOR THE PRODUCTION OF NON-SALINE ESOMEPRAZOLE
EP1801110A1 (en) 2005-12-22 2007-06-27 KRKA, tovarna zdravil, d.d., Novo mesto Esomeprazole arginine salt
ATE428707T1 (de) 2005-12-28 2009-05-15 Union Quimico Farma Verfahren zur herstellung des (s)-enantiomers von omeprazol
EP2000468A1 (en) * 2007-05-09 2008-12-10 Dr. Reddy's Laboratories Ltd. Esomeprazole salts and processes for preparation thereof
WO2009047775A2 (en) * 2007-10-08 2009-04-16 Hetero Drugs Limited Polymorphs of esomeprazole salts
ES2638463T3 (es) 2008-03-10 2017-10-20 Takeda Pharmaceutical Company Limited Cristal de compuesto de bencimidazol
EP2143722A1 (en) 2008-07-09 2010-01-13 Lek Pharmaceuticals D.D. Process for preparation of esomeprazole sodium of high chemical purity and new forms of esomeprazole sodium
WO2010029335A1 (en) 2008-09-09 2010-03-18 Astrazeneca Uk Limited Method for delivering a pharmaceutical composition to patient in need thereof
WO2010151216A1 (en) 2009-06-25 2010-12-29 Astrazeneca Ab Method for treating a patient at risk for developing an nsaid-associated ulcer
CN102884178B (zh) 2009-12-08 2014-12-03 科德克希思公司 拉唑化合物的合成
HUE037616T2 (hu) 2010-12-08 2018-09-28 Codexis Inc Biokatalizátorok és eljárások armodafinil szintéziséhez
BR112014016085A8 (pt) 2011-12-28 2017-07-04 Pozen Inc composições aprimoradas e métodos para distribuição de omeprazol mais ácido acetilsalicílico
RU2501549C1 (ru) 2012-08-30 2013-12-20 Авва Девелопмент Лтд Фармацевтическая композиция для лечения гастроэзофагеальной рефлюксной болезни
CN107043367A (zh) * 2017-05-26 2017-08-15 重庆莱美隆宇药业有限公司 一种中性s‑奥美拉唑的干燥工艺
EP4598528A1 (en) 2022-10-04 2025-08-13 Arsenil Zabirnyk Inhibition of aortic valve calcification

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE7804231L (sv) * 1978-04-14 1979-10-15 Haessle Ab Magsyrasekretionsmedel
SE8301182D0 (sv) * 1983-03-04 1983-03-04 Haessle Ab Novel compounds
GB2189698A (en) * 1986-04-30 1987-11-04 Haessle Ab Coated omeprazole tablets
SE9002043D0 (sv) * 1990-06-07 1990-06-07 Astra Ab Improved method for synthesis
DE4035455A1 (de) * 1990-11-08 1992-05-14 Byk Gulden Lomberg Chem Fab Enantiomerentrennung
SE9301830D0 (sv) * 1993-05-28 1993-05-28 Ab Astra New compounds
US5877192A (en) * 1993-05-28 1999-03-02 Astra Aktiebolag Method for the treatment of gastric acid-related diseases and production of medication using (-) enantiomer of omeprazole
SE9302396D0 (sv) * 1993-07-09 1993-07-09 Ab Astra A novel compound form
EP1078628B1 (en) * 1994-07-08 2008-11-19 AstraZeneca AB Multiple unit tableted dosage form

Also Published As

Publication number Publication date
ATE236898T1 (de) 2003-04-15
PL190377B1 (pl) 2005-12-30
HU227589B1 (en) 2011-09-28
PL334297A1 (en) 2000-02-14
YU28199A (sh) 2002-03-18
RU2184734C2 (ru) 2002-07-10
SI0946547T1 (en) 2003-10-31
IS5070A (is) 1999-06-07
CZ294784B6 (cs) 2005-03-16
NO993068D0 (no) 1999-06-21
EP0946547B1 (en) 2003-04-09
SE9604793L (sv) 1998-06-21
SE9604793D0 (sv) 1996-12-20
JP2001507025A (ja) 2001-05-29
EE9900259A (et) 2000-02-15
TW538039B (en) 2003-06-21
DK0946547T3 (da) 2003-06-30
EE03923B1 (et) 2002-12-16
AR010361A1 (es) 2000-06-07
AU730129B2 (en) 2001-02-22
TR199901410T2 (xx) 1999-08-23
CZ220299A3 (cs) 2000-02-16
EG24414A (en) 2009-05-25
SK76599A3 (en) 1999-12-10
HU0001547D0 (is) 2002-05-29
NO993068L (no) 1999-06-21
IL130450A0 (en) 2000-06-01
JP4402174B2 (ja) 2010-01-20
MY117032A (en) 2004-04-30
CA2274076A1 (en) 1998-07-02
CN1109684C (zh) 2003-05-28
CA2274076C (en) 2008-09-30
EP0946547A1 (en) 1999-10-06
HUP0001547A3 (en) 2002-06-28
SK285151B6 (sk) 2006-07-07
HK1022909A1 (en) 2000-08-25
CN1241183A (zh) 2000-01-12
ID21850A (id) 1999-08-05
DE69720774T2 (de) 2004-02-05
SE510666C2 (sv) 1999-06-14
SA97180739B1 (ar) 2006-05-20
AU5502698A (en) 1998-07-17
PT946547E (pt) 2003-07-31
UA55436C2 (uk) 2003-04-15
US6162816A (en) 2000-12-19
NO317191B1 (no) 2004-09-13
ES2194231T3 (es) 2003-11-16
BR9714059A (pt) 2000-05-09
DE69720774D1 (de) 2003-05-15
HUP0001547A2 (hu) 2002-05-29
WO1998028294A1 (en) 1998-07-02
NZ336024A (en) 2001-02-23
ZA9711046B (en) 1998-06-22
RS49685B (sr) 2007-11-15
KR20000069595A (ko) 2000-11-25

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