ATE236898T1 - S-omeprazol in festform - Google Patents
S-omeprazol in festformInfo
- Publication number
- ATE236898T1 ATE236898T1 AT97951367T AT97951367T ATE236898T1 AT E236898 T1 ATE236898 T1 AT E236898T1 AT 97951367 T AT97951367 T AT 97951367T AT 97951367 T AT97951367 T AT 97951367T AT E236898 T1 ATE236898 T1 AT E236898T1
- Authority
- AT
- Austria
- Prior art keywords
- omeprazole
- solid form
- solid
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE9604793A SE510666C2 (sv) | 1996-12-20 | 1996-12-20 | Nya Kristallmodifikationer |
PCT/SE1997/002125 WO1998028294A1 (en) | 1996-12-20 | 1997-12-16 | A novel compound form |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE236898T1 true ATE236898T1 (de) | 2003-04-15 |
Family
ID=20405146
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT97951367T ATE236898T1 (de) | 1996-12-20 | 1997-12-16 | S-omeprazol in festform |
Country Status (37)
Country | Link |
---|---|
US (1) | US6162816A (de) |
EP (1) | EP0946547B1 (de) |
JP (1) | JP4402174B2 (de) |
KR (1) | KR20000069595A (de) |
CN (1) | CN1109684C (de) |
AR (1) | AR010361A1 (de) |
AT (1) | ATE236898T1 (de) |
AU (1) | AU730129B2 (de) |
BR (1) | BR9714059A (de) |
CA (1) | CA2274076C (de) |
CZ (1) | CZ294784B6 (de) |
DE (1) | DE69720774T2 (de) |
DK (1) | DK0946547T3 (de) |
EE (1) | EE03923B1 (de) |
EG (1) | EG24414A (de) |
ES (1) | ES2194231T3 (de) |
HK (1) | HK1022909A1 (de) |
HU (1) | HU227589B1 (de) |
ID (1) | ID21850A (de) |
IL (1) | IL130450A0 (de) |
IS (1) | IS1981B (de) |
MY (1) | MY117032A (de) |
NO (1) | NO317191B1 (de) |
NZ (1) | NZ336024A (de) |
PL (1) | PL190377B1 (de) |
PT (1) | PT946547E (de) |
RS (1) | RS49685B (de) |
RU (1) | RU2184734C2 (de) |
SA (1) | SA97180739B1 (de) |
SE (1) | SE510666C2 (de) |
SI (1) | SI0946547T1 (de) |
SK (1) | SK285151B6 (de) |
TR (1) | TR199901410T2 (de) |
TW (1) | TW538039B (de) |
UA (1) | UA55436C2 (de) |
WO (1) | WO1998028294A1 (de) |
ZA (1) | ZA9711046B (de) |
Families Citing this family (60)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5840737A (en) | 1996-01-04 | 1998-11-24 | The Curators Of The University Of Missouri | Omeprazole solution and method for using same |
US6699885B2 (en) | 1996-01-04 | 2004-03-02 | The Curators Of The University Of Missouri | Substituted benzimidazole dosage forms and methods of using same |
US6489346B1 (en) | 1996-01-04 | 2002-12-03 | The Curators Of The University Of Missouri | Substituted benzimidazole dosage forms and method of using same |
US6645988B2 (en) | 1996-01-04 | 2003-11-11 | Curators Of The University Of Missouri | Substituted benzimidazole dosage forms and method of using same |
SI20019A (sl) * | 1998-07-13 | 2000-02-29 | LEK, tovarna farmacevtskih in kemi�nih izdelkov, d.d. | Izboljšan postopek sinteze 5-metoksi -2-/(4-metoksi-3,5-dimetil-2-piridil)metil/ sulfinil-1H-benzimidazola |
IL142703A (en) | 1998-11-10 | 2006-04-10 | Astrazeneca Ab | Crystalline form of omeprazole |
UA72748C2 (en) * | 1998-11-10 | 2005-04-15 | Astrazeneca Ab | A novel crystalline form of omeprazole |
JP3926936B2 (ja) | 1998-11-16 | 2007-06-06 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | スルホキシド誘導体・アセトン錯体およびその製造法 |
SE9804003D0 (sv) | 1998-11-23 | 1998-11-23 | Astra Ab | A method of producing drug particles |
SE9900274D0 (sv) * | 1999-01-28 | 1999-01-28 | Astra Ab | New compound |
JP2000344739A (ja) * | 1999-06-01 | 2000-12-12 | Sumitomo Chem Co Ltd | N−保護−アゼチジン−2−カルボン酸の製造方法 |
TWI289557B (en) | 1999-06-17 | 2007-11-11 | Takeda Chemical Industries Ltd | A crystal of a hydrate of (R)-2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridyl]methyl]sulfinyl]-1H-benzimidazole |
SE0000773D0 (sv) * | 2000-03-08 | 2000-03-08 | Astrazeneca Ab | New formulation |
SE0000774D0 (sv) | 2000-03-08 | 2000-03-08 | Astrazeneca Ab | New formulation |
DK1293507T3 (da) | 2000-05-15 | 2007-12-27 | Takeda Pharmaceutical | Fremgangsmåde til fremstilling af krystaller |
GB0016040D0 (en) * | 2000-06-29 | 2000-08-23 | Glaxo Group Ltd | Novel process for preparing crystalline particles |
WO2002012225A1 (fr) | 2000-08-04 | 2002-02-14 | Takeda Chemical Industries, Ltd. | Sels de composé à base de benzimidazole et leurs applications |
SI20875A (sl) | 2001-04-25 | 2002-10-31 | LEK, tovarna farmacevtskih in kemi�nih izdelkov, d.d. | Kristalna oblika omeprazola |
US8206741B2 (en) | 2001-06-01 | 2012-06-26 | Pozen Inc. | Pharmaceutical compositions for the coordinated delivery of NSAIDs |
DE60237087D1 (de) | 2001-06-01 | 2010-09-02 | Pozen Inc | Pharmazeutische zusammensetzungen für die koordinierte abgabe von nsaid |
GB2376231A (en) | 2001-06-06 | 2002-12-11 | Cipla Ltd | Benzimidazole-cyclodextrin inclusion complex |
SE0102993D0 (sv) | 2001-09-07 | 2001-09-07 | Astrazeneca Ab | New self emulsifying drug delivery system |
CN100378093C (zh) * | 2002-06-27 | 2008-04-02 | 雷迪实验室有限公司 | 一种制备包括无定形艾美拉唑及其盐在内的光学纯或光学浓缩的亚砜化合物的方法 |
WO2004002982A2 (en) * | 2002-06-27 | 2004-01-08 | Dr. Reddy's Laboratories Limited | A process for preparation of optically pure or optically enriched sulfoxide compounds, including amorphous esomeprazole and salts thereof |
AU2003262992A1 (en) * | 2002-08-30 | 2004-03-19 | Reddy's Laboratories Limited | Amorphous hydrates of esomeprazole magnesium and process for the preparation thereof |
CA2771725C (en) | 2002-10-16 | 2015-08-18 | Takeda Pharmaceutical Company Limited | Solid preparation comprising a non-toxic base and a proton pump inhibitor |
BR0315574A (pt) * | 2002-10-22 | 2005-09-20 | Ranbaxy Lab Ltd | Forma amorfa de esomeprazol, composição farmacêutica contendo o mesmo e processo para sua preparação |
WO2004046134A2 (en) * | 2002-11-18 | 2004-06-03 | Dr. Reddy's Laboratories Limited | Crystalline form ii of esomeprazole magnesium trihydrate and process for its preparation |
BRPI0407906A (pt) * | 2003-02-28 | 2006-02-14 | Ranbaxy Lab Ltd | polimorfos de s-omeprazol |
CA2516600C (en) * | 2003-03-24 | 2011-04-05 | Eisai Co., Ltd. | Process for production of sulfoxide proton pump inhibitors in the amorphous state |
EP1633736A1 (de) * | 2003-05-05 | 2006-03-15 | Ranbaxy Laboratories Limited | Barium salz eines benzimidazol-derivats |
US8993599B2 (en) | 2003-07-18 | 2015-03-31 | Santarus, Inc. | Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them |
SE0400410D0 (sv) | 2004-02-20 | 2004-02-20 | Astrazeneca Ab | New compounds |
US8906940B2 (en) | 2004-05-25 | 2014-12-09 | Santarus, Inc. | Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them |
US8815916B2 (en) | 2004-05-25 | 2014-08-26 | Santarus, Inc. | Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them |
EP1768668A2 (de) | 2004-06-16 | 2007-04-04 | Tap Pharmaceutical Products, Inc. | Multi-ppi-dosierform |
JP5457632B2 (ja) * | 2004-06-24 | 2014-04-02 | アストラゼネカ・アクチエボラーグ | エソメプラゾールのナトリウム塩の製造に使用するための結晶の改変型の作成方法 |
ES2246149B1 (es) * | 2004-07-02 | 2007-06-01 | Esteve Quimica, S.A. | Formas solidas de la sal magnesica de s-omeprazol y procedimientos para su preparacion. |
US20090298884A1 (en) * | 2005-05-06 | 2009-12-03 | Glenmark Generics Ltd. | Esomeprazole Strontium Salt, Process For Its Preparation and Pharmaceutical Compositions Containing Same |
EP1907375B1 (de) * | 2005-06-08 | 2013-07-24 | LEK Pharmaceuticals d.d. | Kristallines solvat von omeprazol-natrium |
WO2006134605A1 (en) * | 2005-06-15 | 2006-12-21 | Hetero Drugs Limited | Amorphous esomeprazole hydrate |
NL2000126C2 (nl) * | 2005-07-15 | 2008-01-29 | Solvay | Werkwijze voor de vervaardiging van eptifibatide. |
US20070043085A1 (en) * | 2005-08-19 | 2007-02-22 | Glenmark Pharmaceuticals Limited | Process for the preparation of amorphous form of neutral esomeprazole |
US7576219B2 (en) | 2005-10-26 | 2009-08-18 | Hanmi Pharm. Co., Ltd | Crystalline S-omeprazole strontium hydrate, method for preparing same, and pharmaceutical composition containing same |
WO2007054951A1 (en) * | 2005-11-14 | 2007-05-18 | Hetero Drugs Limited | Process for amorphous esomeprazole |
NZ568471A (en) | 2005-12-05 | 2010-09-30 | Astrazeneca Ab | New process for the preparation of esomeprazole non-salt form |
EP1801110A1 (de) | 2005-12-22 | 2007-06-27 | KRKA, tovarna zdravil, d.d., Novo mesto | Argininsalz des Esomeprazols |
KR101289215B1 (ko) | 2005-12-28 | 2013-07-29 | 유니온 퀴미코 파르마세우티카, 에스.에이. | 오메프라졸의 (에스)-엔안티오머의 제조 방법 |
EP2000468A1 (de) * | 2007-05-09 | 2008-12-10 | Dr. Reddy's Laboratories Ltd. | Esomeprazolsalze und Verfahren zur Herstellung davon |
EP2195309A4 (de) | 2007-10-08 | 2013-04-24 | Hetero Drugs Ltd | Polymorphe von esomeprazolsalzen |
PE20091680A1 (es) | 2008-03-10 | 2009-11-16 | Takeda Pharmaceutical | Cristal de compuestos de bencimidazol |
EP2143722A1 (de) | 2008-07-09 | 2010-01-13 | Lek Pharmaceuticals D.D. | Verfahren zur Herstellung von Esomeprazol-Natrium von hoher chemischer Reinheit und neue Formen von Esomeprazol-Natrium |
EP2344139A1 (de) * | 2008-09-09 | 2011-07-20 | AstraZeneca AB | Verfahren zur abgabe einer pharmazeutischen zusammensetzung an einen patienten, der diese benötigt |
EP2445499A4 (de) | 2009-06-25 | 2013-02-27 | Astrazeneca Ab | Verfahren zur behandlung eines patienten mit risiko der entwicklung eines nsaid-assoziierten geschwürs |
CN102884178B (zh) | 2009-12-08 | 2014-12-03 | 科德克希思公司 | 拉唑化合物的合成 |
HUE037616T2 (hu) | 2010-12-08 | 2018-09-28 | Codexis Inc | Biokatalizátorok és eljárások armodafinil szintéziséhez |
BR112014016085A8 (pt) | 2011-12-28 | 2017-07-04 | Pozen Inc | composições aprimoradas e métodos para distribuição de omeprazol mais ácido acetilsalicílico |
RU2501549C1 (ru) | 2012-08-30 | 2013-12-20 | Авва Девелопмент Лтд | Фармацевтическая композиция для лечения гастроэзофагеальной рефлюксной болезни |
CN107043367A (zh) * | 2017-05-26 | 2017-08-15 | 重庆莱美隆宇药业有限公司 | 一种中性s‑奥美拉唑的干燥工艺 |
WO2024075017A1 (en) | 2022-10-04 | 2024-04-11 | Zabirnyk Arsenii | Inhibition of aortic valve calcification |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE7804231L (sv) * | 1978-04-14 | 1979-10-15 | Haessle Ab | Magsyrasekretionsmedel |
SE8301182D0 (sv) * | 1983-03-04 | 1983-03-04 | Haessle Ab | Novel compounds |
GB2189698A (en) * | 1986-04-30 | 1987-11-04 | Haessle Ab | Coated omeprazole tablets |
DE4035455A1 (de) * | 1990-11-08 | 1992-05-14 | Byk Gulden Lomberg Chem Fab | Enantiomerentrennung |
SE9301830D0 (sv) * | 1993-05-28 | 1993-05-28 | Ab Astra | New compounds |
US5877192A (en) * | 1993-05-28 | 1999-03-02 | Astra Aktiebolag | Method for the treatment of gastric acid-related diseases and production of medication using (-) enantiomer of omeprazole |
SE9302396D0 (sv) * | 1993-07-09 | 1993-07-09 | Ab Astra | A novel compound form |
EE03305B1 (et) * | 1994-07-08 | 2000-12-15 | Astra Aktiebolag | Paljuosaline tableteeritud annusvorm I |
-
1996
- 1996-12-20 SE SE9604793A patent/SE510666C2/sv unknown
-
1997
- 1997-12-08 TW TW086118449A patent/TW538039B/zh not_active IP Right Cessation
- 1997-12-09 ZA ZA9711046A patent/ZA9711046B/xx unknown
- 1997-12-16 TR TR1999/01410T patent/TR199901410T2/xx unknown
- 1997-12-16 ID IDW990483A patent/ID21850A/id unknown
- 1997-12-16 PT PT97951367T patent/PT946547E/pt unknown
- 1997-12-16 HU HU0001547A patent/HU227589B1/hu not_active IP Right Cessation
- 1997-12-16 AT AT97951367T patent/ATE236898T1/de active
- 1997-12-16 EE EEP199900259A patent/EE03923B1/xx not_active IP Right Cessation
- 1997-12-16 AU AU55026/98A patent/AU730129B2/en not_active Ceased
- 1997-12-16 IL IL13045097A patent/IL130450A0/xx not_active IP Right Cessation
- 1997-12-16 EP EP97951367A patent/EP0946547B1/de not_active Expired - Lifetime
- 1997-12-16 NZ NZ336024A patent/NZ336024A/en not_active IP Right Cessation
- 1997-12-16 CZ CZ19992202A patent/CZ294784B6/cs not_active IP Right Cessation
- 1997-12-16 RU RU99116303/04A patent/RU2184734C2/ru not_active IP Right Cessation
- 1997-12-16 DE DE69720774T patent/DE69720774T2/de not_active Expired - Lifetime
- 1997-12-16 JP JP52868598A patent/JP4402174B2/ja not_active Expired - Fee Related
- 1997-12-16 KR KR1019997005574A patent/KR20000069595A/ko active Search and Examination
- 1997-12-16 SK SK765-99A patent/SK285151B6/sk not_active IP Right Cessation
- 1997-12-16 CN CN97180849A patent/CN1109684C/zh not_active Expired - Fee Related
- 1997-12-16 RS YUP-281/99A patent/RS49685B/sr unknown
- 1997-12-16 BR BR9714059-7A patent/BR9714059A/pt not_active Application Discontinuation
- 1997-12-16 DK DK97951367T patent/DK0946547T3/da active
- 1997-12-16 UA UA99073869A patent/UA55436C2/uk unknown
- 1997-12-16 WO PCT/SE1997/002125 patent/WO1998028294A1/en not_active Application Discontinuation
- 1997-12-16 PL PL97334297A patent/PL190377B1/pl not_active IP Right Cessation
- 1997-12-16 ES ES97951367T patent/ES2194231T3/es not_active Expired - Lifetime
- 1997-12-16 AR ARP970105920A patent/AR010361A1/es active IP Right Grant
- 1997-12-16 CA CA002274076A patent/CA2274076C/en not_active Expired - Fee Related
- 1997-12-16 SI SI9730528T patent/SI0946547T1/xx unknown
- 1997-12-16 US US09/000,154 patent/US6162816A/en not_active Expired - Lifetime
- 1997-12-19 MY MYPI97006176A patent/MY117032A/en unknown
- 1997-12-20 EG EG136097A patent/EG24414A/xx active
- 1997-12-27 SA SA97180739A patent/SA97180739B1/ar unknown
-
1999
- 1999-06-07 IS IS5070A patent/IS1981B/is unknown
- 1999-06-21 NO NO19993068A patent/NO317191B1/no not_active IP Right Cessation
-
2000
- 2000-03-31 HK HK00101986A patent/HK1022909A1/xx not_active IP Right Cessation
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