ES2194231T3 - Una nueva forma de compuesto. - Google Patents

Una nueva forma de compuesto.

Info

Publication number
ES2194231T3
ES2194231T3 ES97951367T ES97951367T ES2194231T3 ES 2194231 T3 ES2194231 T3 ES 2194231T3 ES 97951367 T ES97951367 T ES 97951367T ES 97951367 T ES97951367 T ES 97951367T ES 2194231 T3 ES2194231 T3 ES 2194231T3
Authority
ES
Spain
Prior art keywords
compound
new form
invention refers
omeprozol
omeprazol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES97951367T
Other languages
English (en)
Inventor
Martin Bohlin
Karol Horvath
Unge Sverker Von
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AstraZeneca AB
Original Assignee
AstraZeneca AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=20405146&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2194231(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by AstraZeneca AB filed Critical AstraZeneca AB
Application granted granted Critical
Publication of ES2194231T3 publication Critical patent/ES2194231T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics

Abstract

ESTA INVENCION SE REFIERE AL S - OMEPROZOL EN FORMA NEUTRA CARACTERIZADA POR UN ESTADO SOLIDO, PREFERENTEMENTE, UN ESTADO PARCIALMENTE CRISTALINO O CASI CRISTALINO, COMO LA FORMA A O B. ESTA INVENCION SE REFIERE TAMBIEN A UNOS PROCEDIMIENTOS DE PREPARACION DE S - OMEPRAZOL Y SU USO EN MEDICINA.
ES97951367T 1996-12-20 1997-12-16 Una nueva forma de compuesto. Expired - Lifetime ES2194231T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9604793A SE510666C2 (sv) 1996-12-20 1996-12-20 Nya Kristallmodifikationer

Publications (1)

Publication Number Publication Date
ES2194231T3 true ES2194231T3 (es) 2003-11-16

Family

ID=20405146

Family Applications (1)

Application Number Title Priority Date Filing Date
ES97951367T Expired - Lifetime ES2194231T3 (es) 1996-12-20 1997-12-16 Una nueva forma de compuesto.

Country Status (37)

Country Link
US (1) US6162816A (es)
EP (1) EP0946547B1 (es)
JP (1) JP4402174B2 (es)
KR (1) KR20000069595A (es)
CN (1) CN1109684C (es)
AR (1) AR010361A1 (es)
AT (1) ATE236898T1 (es)
AU (1) AU730129B2 (es)
BR (1) BR9714059A (es)
CA (1) CA2274076C (es)
CZ (1) CZ294784B6 (es)
DE (1) DE69720774T2 (es)
DK (1) DK0946547T3 (es)
EE (1) EE03923B1 (es)
EG (1) EG24414A (es)
ES (1) ES2194231T3 (es)
HK (1) HK1022909A1 (es)
HU (1) HU227589B1 (es)
ID (1) ID21850A (es)
IL (1) IL130450A0 (es)
IS (1) IS1981B (es)
MY (1) MY117032A (es)
NO (1) NO317191B1 (es)
NZ (1) NZ336024A (es)
PL (1) PL190377B1 (es)
PT (1) PT946547E (es)
RS (1) RS49685B (es)
RU (1) RU2184734C2 (es)
SA (1) SA97180739B1 (es)
SE (1) SE510666C2 (es)
SI (1) SI0946547T1 (es)
SK (1) SK285151B6 (es)
TR (1) TR199901410T2 (es)
TW (1) TW538039B (es)
UA (1) UA55436C2 (es)
WO (1) WO1998028294A1 (es)
ZA (1) ZA9711046B (es)

Families Citing this family (60)

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US6699885B2 (en) 1996-01-04 2004-03-02 The Curators Of The University Of Missouri Substituted benzimidazole dosage forms and methods of using same
US5840737A (en) 1996-01-04 1998-11-24 The Curators Of The University Of Missouri Omeprazole solution and method for using same
US6645988B2 (en) 1996-01-04 2003-11-11 Curators Of The University Of Missouri Substituted benzimidazole dosage forms and method of using same
SI20019A (sl) 1998-07-13 2000-02-29 LEK, tovarna farmacevtskih in kemi�nih izdelkov, d.d. Izboljšan postopek sinteze 5-metoksi -2-/(4-metoksi-3,5-dimetil-2-piridil)metil/ sulfinil-1H-benzimidazola
UA72748C2 (en) * 1998-11-10 2005-04-15 Astrazeneca Ab A novel crystalline form of omeprazole
IL142703A (en) 1998-11-10 2006-04-10 Astrazeneca Ab Crystalline form of omeprazole
JP3926936B2 (ja) 1998-11-16 2007-06-06 エーザイ・アール・アンド・ディー・マネジメント株式会社 スルホキシド誘導体・アセトン錯体およびその製造法
SE9804003D0 (sv) * 1998-11-23 1998-11-23 Astra Ab A method of producing drug particles
SE9900274D0 (sv) 1999-01-28 1999-01-28 Astra Ab New compound
JP2000344739A (ja) * 1999-06-01 2000-12-12 Sumitomo Chem Co Ltd Ｎ−保護−アゼチジン−２−カルボン酸の製造方法
TWI275587B (en) 1999-06-17 2007-03-11 Takeda Chemical Industries Ltd A crystal of (R)-2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridyl]methyl]sulfinyl]-1H-benzimidazole
SE0000774D0 (sv) 2000-03-08 2000-03-08 Astrazeneca Ab New formulation
SE0000773D0 (sv) * 2000-03-08 2000-03-08 Astrazeneca Ab New formulation
CA2762960C (en) * 2000-05-15 2014-07-22 Takeda Pharmaceutical Company Limited Recrystallization processes for obtaining anhydrous optically active lansoprazole
GB0016040D0 (en) * 2000-06-29 2000-08-23 Glaxo Group Ltd Novel process for preparing crystalline particles
JP5412023B2 (ja) 2000-08-04 2014-02-12 武田薬品工業株式会社 ベンズイミダゾール化合物の塩およびその用途
SI20875A (sl) * 2001-04-25 2002-10-31 LEK, tovarna farmacevtskih in kemi�nih izdelkov, d.d. Kristalna oblika omeprazola
US8206741B2 (en) 2001-06-01 2012-06-26 Pozen Inc. Pharmaceutical compositions for the coordinated delivery of NSAIDs
MXPA03011017A (es) 2001-06-01 2005-04-29 Pozen Inc Composiciones farmaceuticas para la entrega coordinada de nsaids.
GB2376231A (en) 2001-06-06 2002-12-11 Cipla Ltd Benzimidazole-cyclodextrin inclusion complex
SE0102993D0 (sv) 2001-09-07 2001-09-07 Astrazeneca Ab New self emulsifying drug delivery system
WO2004002982A2 (en) * 2002-06-27 2004-01-08 Dr. Reddy's Laboratories Limited A process for preparation of optically pure or optically enriched sulfoxide compounds, including amorphous esomeprazole and salts thereof
CN100378093C (zh) * 2002-06-27 2008-04-02 雷迪实验室有限公司 一种制备包括无定形艾美拉唑及其盐在内的光学纯或光学浓缩的亚砜化合物的方法
CA2501424A1 (en) * 2002-08-30 2004-03-11 Dr. Reddy's Laboratories Limited Amorphous hydrates of esomeprazole magnesium and process for the preparation thereof
EP1552833B1 (en) 2002-10-16 2016-12-28 Takeda Pharmaceutical Company Limited Process for producing an amorphous optically active isomer of lansoprazole
EA200500673A1 (ru) * 2002-10-22 2005-12-29 Рэнбакси Лабораториз Лимитед Аморфная форма соли эзомепразола, способ ее получения и фармацевтическая композиция на её основе
US20040242642A1 (en) * 2002-11-18 2004-12-02 Dr. Reddy's Laboratories Limited Crystalline esomeprazole compounds and process for the preparation thereof
CN1777598A (zh) * 2003-02-28 2006-05-24 兰贝克赛实验室有限公司 S－奥美拉唑的多晶型物
EP1607395B1 (en) * 2003-03-24 2011-05-04 Eisai R&D Management Co., Ltd. Process for the preparation of amorphous rabeprazole sodium salt
EP1633736A1 (en) * 2003-05-05 2006-03-15 Ranbaxy Laboratories Limited Barium salt of benzimidazole derivative
US8993599B2 (en) 2003-07-18 2015-03-31 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
SE0400410D0 (sv) 2004-02-20 2004-02-20 Astrazeneca Ab New compounds
US8906940B2 (en) 2004-05-25 2014-12-09 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
US8815916B2 (en) 2004-05-25 2014-08-26 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
JP5563735B2 (ja) 2004-06-16 2014-07-30 タケダ ファーマシューティカルズ ユー．エス．エー． インコーポレイティド Ｐｐｉ多回剤形
JP5457632B2 (ja) * 2004-06-24 2014-04-02 アストラゼネカ・アクチエボラーグ エソメプラゾールのナトリウム塩の製造に使用するための結晶の改変型の作成方法
ES2246149B1 (es) * 2004-07-02 2007-06-01 Esteve Quimica, S.A. Formas solidas de la sal magnesica de s-omeprazol y procedimientos para su preparacion.
RU2007145207A (ru) * 2005-05-06 2009-06-20 Гленмарк Фармасьютикалз Лимитед (In) Стронциваемая соль эзомепразола, способ ее получения и содержащее ее фармацевтические композиции
WO2006131338A2 (en) * 2005-06-08 2006-12-14 Lek Pharmaceuticals D.D. Crystalline solvate of omeprazole sodium
WO2006134605A1 (en) * 2005-06-15 2006-12-21 Hetero Drugs Limited Amorphous esomeprazole hydrate
NL2000126C2 (nl) * 2005-07-15 2008-01-29 Solvay Werkwijze voor de vervaardiging van eptifibatide.
US20070043085A1 (en) * 2005-08-19 2007-02-22 Glenmark Pharmaceuticals Limited Process for the preparation of amorphous form of neutral esomeprazole
US7576219B2 (en) 2005-10-26 2009-08-18 Hanmi Pharm. Co., Ltd Crystalline S-omeprazole strontium hydrate, method for preparing same, and pharmaceutical composition containing same
US20090082572A1 (en) * 2005-11-14 2009-03-26 Hetero Drugs Limited Process for amorphous esomeprazole
JP2009518394A (ja) * 2005-12-05 2009-05-07 アストラゼネカ・アクチエボラーグ エソメプラゾールの非塩形態の新規の製造方法
EP1801110A1 (en) 2005-12-22 2007-06-27 KRKA, tovarna zdravil, d.d., Novo mesto Esomeprazole arginine salt
DE602006006352D1 (de) 2005-12-28 2009-05-28 Union Quimico Farma Verfahren zur herstellung des (s)-enantiomers von omeprazol
EP2000468A1 (en) * 2007-05-09 2008-12-10 Dr. Reddy's Laboratories Ltd. Esomeprazole salts and processes for preparation thereof
EP2195309A4 (en) 2007-10-08 2013-04-24 Hetero Drugs Ltd SALT POLYMORPHS OF THE ESOMEPRAZOLE
JP2011513202A (ja) 2008-03-10 2011-04-28 武田薬品工業株式会社 ベンズイミダゾール化合物の結晶
EP2143722A1 (en) 2008-07-09 2010-01-13 Lek Pharmaceuticals D.D. Process for preparation of esomeprazole sodium of high chemical purity and new forms of esomeprazole sodium
EP2344139A1 (en) * 2008-09-09 2011-07-20 AstraZeneca AB Method for delivering a pharmaceutical composition to patient in need thereof
EA201290026A1 (ru) 2009-06-25 2012-07-30 Астразенека Аб Способ лечения пациента, имеющего риск развития язвы, связанной с приемом нестероидных противовоспалительных средств (nsaid)
US8895271B2 (en) 2009-12-08 2014-11-25 Codexis, Inc. Synthesis of prazole compounds
HUE037616T2 (hu) 2010-12-08 2018-09-28 Codexis Inc Biokatalizátorok és eljárások armodafinil szintéziséhez
BR112014016085A8 (pt) 2011-12-28 2017-07-04 Pozen Inc composições aprimoradas e métodos para distribuição de omeprazol mais ácido acetilsalicílico
RU2501549C1 (ru) 2012-08-30 2013-12-20 Авва Девелопмент Лтд Фармацевтическая композиция для лечения гастроэзофагеальной рефлюксной болезни
CN107043367A (zh) * 2017-05-26 2017-08-15 重庆莱美隆宇药业有限公司 一种中性s‑奥美拉唑的干燥工艺
WO2024075017A1 (en) 2022-10-04 2024-04-11 Zabirnyk Arsenii Inhibition of aortic valve calcification

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SE7804231L (sv) * 1978-04-14 1979-10-15 Haessle Ab Magsyrasekretionsmedel
SE8301182D0 (sv) * 1983-03-04 1983-03-04 Haessle Ab Novel compounds
GB2189698A (en) * 1986-04-30 1987-11-04 Haessle Ab Coated omeprazole tablets
DE4035455A1 (de) * 1990-11-08 1992-05-14 Byk Gulden Lomberg Chem Fab Enantiomerentrennung
SE9301830D0 (sv) * 1993-05-28 1993-05-28 Ab Astra New compounds
US5877192A (en) * 1993-05-28 1999-03-02 Astra Aktiebolag Method for the treatment of gastric acid-related diseases and production of medication using (-) enantiomer of omeprazole
SE9302396D0 (sv) * 1993-07-09 1993-07-09 Ab Astra A novel compound form
JP3350054B2 (ja) * 1994-07-08 2002-11-25 アストラゼネカ・アクチエボラーグ 複数単位の錠剤化された剤形▲ｉ▼

Also Published As

Publication number Publication date
NO317191B1 (no) 2004-09-13
PL334297A1 (en) 2000-02-14
NO993068L (no) 1999-06-21
CN1109684C (zh) 2003-05-28
UA55436C2 (uk) 2003-04-15
AU730129B2 (en) 2001-02-22
EG24414A (en) 2009-05-25
SK285151B6 (sk) 2006-07-07
US6162816A (en) 2000-12-19
HU227589B1 (en) 2011-09-28
CA2274076A1 (en) 1998-07-02
SI0946547T1 (en) 2003-10-31
DK0946547T3 (da) 2003-06-30
HUP0001547A3 (en) 2002-06-28
SE510666C2 (sv) 1999-06-14
SE9604793L (sv) 1998-06-21
RS49685B (sr) 2007-11-15
JP2001507025A (ja) 2001-05-29
DE69720774D1 (de) 2003-05-15
EP0946547B1 (en) 2003-04-09
CN1241183A (zh) 2000-01-12
TW538039B (en) 2003-06-21
CZ294784B6 (cs) 2005-03-16
NO993068D0 (no) 1999-06-21
WO1998028294A1 (en) 1998-07-02
SA97180739B1 (ar) 2006-05-20
HUP0001547A2 (hu) 2002-05-29
NZ336024A (en) 2001-02-23
IL130450A0 (en) 2000-06-01
CZ220299A3 (cs) 2000-02-16
EE9900259A (et) 2000-02-15
YU28199A (sh) 2002-03-18
PT946547E (pt) 2003-07-31
SE9604793D0 (sv) 1996-12-20
AR010361A1 (es) 2000-06-07
ATE236898T1 (de) 2003-04-15
SK76599A3 (en) 1999-12-10
HU0001547D0 (es) 2002-05-29
DE69720774T2 (de) 2004-02-05
IS1981B (is) 2005-01-14
MY117032A (en) 2004-04-30
CA2274076C (en) 2008-09-30
ID21850A (id) 1999-08-05
JP4402174B2 (ja) 2010-01-20
AU5502698A (en) 1998-07-17
HK1022909A1 (en) 2000-08-25
EP0946547A1 (en) 1999-10-06
KR20000069595A (ko) 2000-11-25
TR199901410T2 (xx) 1999-08-23
PL190377B1 (pl) 2005-12-30
BR9714059A (pt) 2000-05-09
EE03923B1 (et) 2002-12-16
ZA9711046B (en) 1998-06-22
RU2184734C2 (ru) 2002-07-10
IS5070A (is) 1999-06-07

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