RU2317303C1 - Ингибиторы вируса гепатита с - Google Patents

Ингибиторы вируса гепатита с Download PDF

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RU2317303C1
RU2317303C1 RU2006134703/04A RU2006134703A RU2317303C1 RU 2317303 C1 RU2317303 C1 RU 2317303C1 RU 2006134703/04 A RU2006134703/04 A RU 2006134703/04A RU 2006134703 A RU2006134703 A RU 2006134703A RU 2317303 C1 RU2317303 C1 RU 2317303C1
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Russia
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hepatitis
virus inhibitors
virus
inhibitors
tbl
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RU2006134703/04A
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Ксианг-донг Элан ВАНГ
Ли-Кванг САН
Синг-Юен Сит
Най Син
Пол Майкл Скола
Пиясена Хевавасам
Эндрю Чарлз ГУД
Ян ЧЕН
Джеффри Эллен КЭМПБЕЛЛ
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Бристол-Маерс Сквибб Компани
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    • C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
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Abstract

Описываются соединения, которые ингибируют функционирование NS3 протеазы, кодируемой вирусом гепатита C. 6 н.п. ф-лы, 2 табл.

Description

Текст описания приведен в факсимильном виде.
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Figure 00000559
Figure 00000560
Figure 00000561
Figure 00000562
Figure 00000563
Figure 00000564
Figure 00000565
Figure 00000566
Figure 00000567
Figure 00000568
Figure 00000569
Figure 00000570
Figure 00000571
Figure 00000572
Figure 00000573
Figure 00000574
Figure 00000575
Figure 00000576
Figure 00000577
Figure 00000578
Figure 00000579
Figure 00000580
Figure 00000581
Figure 00000582
Figure 00000583
Figure 00000584
Figure 00000585
Figure 00000586
Figure 00000587
Figure 00000588
Figure 00000589
Figure 00000590
Figure 00000591
Figure 00000592
Figure 00000593
Figure 00000594
Figure 00000595
Figure 00000596
Figure 00000597
Figure 00000598
Figure 00000599
Figure 00000600
Figure 00000601
Figure 00000602
Figure 00000603
Figure 00000604
Figure 00000605

Claims (6)

1. Соединение, выбранное из
Figure 00000606
Figure 00000607
Figure 00000608
Figure 00000609
Figure 00000610
Figure 00000611
Figure 00000612
Figure 00000613
Figure 00000614
Figure 00000615
Figure 00000616
Figure 00000617
Figure 00000618
Figure 00000619
Figure 00000620
Figure 00000621
Figure 00000622
Figure 00000623
Figure 00000624
и
Figure 00000625
2. Соединение, выбранное из
Figure 00000626
Figure 00000627
Figure 00000628
Figure 00000629
Figure 00000630
Figure 00000631
Figure 00000632
Figure 00000633
Figure 00000634
Figure 00000635
Figure 00000636
Figure 00000637
Figure 00000638
Figure 00000639
Figure 00000640
Figure 00000641
Figure 00000642
Figure 00000643
Figure 00000644
и
Figure 00000645
3. Соединение, выбранное из
Figure 00000646
Figure 00000647
Figure 00000648
Figure 00000649
Figure 00000650
Figure 00000651
Figure 00000652
Figure 00000653
Figure 00000654
Figure 00000655
Figure 00000656
Figure 00000657
Figure 00000658
Figure 00000659
Figure 00000660
Figure 00000661
Figure 00000662
Figure 00000663
Figure 00000664
и
Figure 00000665
4. Соединение, выбранное из
Figure 00000666
Figure 00000667
Figure 00000668
Figure 00000669
Figure 00000670
Figure 00000671
Figure 00000672
Figure 00000673
Figure 00000674
Figure 00000675
Figure 00000676
Figure 00000677
Figure 00000678
Figure 00000679
Figure 00000680
Figure 00000681
Figure 00000682
Figure 00000683
Figure 00000684
и
Figure 00000685
5. Соединение, выбранное из
Figure 00000686
Figure 00000687
Figure 00000688
Figure 00000689
Figure 00000690
Figure 00000691
Figure 00000692
Figure 00000693
Figure 00000694
Figure 00000695
Figure 00000696
Figure 00000697
Figure 00000698
Figure 00000699
Figure 00000700
Figure 00000701
Figure 00000702
Figure 00000703
Figure 00000704
и
Figure 00000705
6. Соединение, выбранное из
Figure 00000706
Figure 00000707
Figure 00000708
Figure 00000709
Figure 00000710
Figure 00000711
Figure 00000712
Figure 00000713
Figure 00000714
Figure 00000715
Figure 00000716
Figure 00000717
Figure 00000718
Figure 00000719
Figure 00000720
Figure 00000721
Figure 00000722
и
Figure 00000723
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