MX2008001402A - Inhibidores macrociclicos del virus de la hepatitis c. - Google Patents

Inhibidores macrociclicos del virus de la hepatitis c.

Info

Publication number
MX2008001402A
MX2008001402A MX2008001402A MX2008001402A MX2008001402A MX 2008001402 A MX2008001402 A MX 2008001402A MX 2008001402 A MX2008001402 A MX 2008001402A MX 2008001402 A MX2008001402 A MX 2008001402A MX 2008001402 A MX2008001402 A MX 2008001402A
Authority
MX
Mexico
Prior art keywords
hepatitis
virus
macrocyclic inhibitors
inhibitors
macrocyclic
Prior art date
Application number
MX2008001402A
Other languages
English (en)
Inventor
Vreken Wim Van De
Kock Herman Augustinus De
Pierre Jean-Marie Bernard Raboisson
Dominique Louis Nestor Ghislain Surleraux
Kenneth Alan Simmen
Original Assignee
Tibotec Pharm Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tibotec Pharm Ltd filed Critical Tibotec Pharm Ltd
Publication of MX2008001402A publication Critical patent/MX2008001402A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Virology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Inhibidores de la replicacion del VHC de formula (I), donde W es un heterociclo de formula (II), (III), (IV) o (V); y las variables restantes son como se definieron en la especificacion (ver formulas (I), (II), (III), (IV) y (V)).
MX2008001402A 2005-07-29 2006-07-28 Inhibidores macrociclicos del virus de la hepatitis c. MX2008001402A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP05107072 2005-07-29
PCT/EP2006/064818 WO2007014924A1 (en) 2005-07-29 2006-07-28 Macrocyclic inhibitors of hepatitis c virus

Publications (1)

Publication Number Publication Date
MX2008001402A true MX2008001402A (es) 2008-04-04

Family

ID=35583505

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2008001402A MX2008001402A (es) 2005-07-29 2006-07-28 Inhibidores macrociclicos del virus de la hepatitis c.

Country Status (15)

Country Link
US (2) US8183277B2 (es)
EP (1) EP1913015B1 (es)
JP (1) JP5230416B2 (es)
CN (1) CN101273052B (es)
AR (1) AR057704A1 (es)
BR (1) BRPI0614696A2 (es)
DK (1) DK1913015T3 (es)
ES (1) ES2449540T3 (es)
MX (1) MX2008001402A (es)
MY (1) MY142972A (es)
PL (1) PL1913015T3 (es)
RU (1) RU2436787C2 (es)
SI (1) SI1913015T1 (es)
TW (1) TWI412535B (es)
WO (1) WO2007014924A1 (es)

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EP2417134B1 (en) 2009-04-08 2017-05-17 Idenix Pharmaceuticals LLC. Macrocyclic serine protease inhibitors
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WO2012092411A2 (en) 2010-12-30 2012-07-05 Enanta Pharmaceuticals, Inc. Phenanthridine macrocyclic hepatitis c serine protease inhibitors
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US8957203B2 (en) 2011-05-05 2015-02-17 Bristol-Myers Squibb Company Hepatitis C virus inhibitors
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Also Published As

Publication number Publication date
US8183277B2 (en) 2012-05-22
WO2007014924A1 (en) 2007-02-08
SI1913015T1 (sl) 2014-05-30
CN101273052A (zh) 2008-09-24
BRPI0614696A2 (pt) 2011-04-12
CN101273052B (zh) 2016-01-13
RU2436787C2 (ru) 2011-12-20
US20080262058A1 (en) 2008-10-23
JP5230416B2 (ja) 2013-07-10
ES2449540T3 (es) 2014-03-20
RU2008107726A (ru) 2009-09-10
US8754116B2 (en) 2014-06-17
TW200728317A (en) 2007-08-01
TWI412535B (zh) 2013-10-21
EP1913015B1 (en) 2013-12-11
JP2009502887A (ja) 2009-01-29
MY142972A (en) 2011-01-31
US20120202859A1 (en) 2012-08-09
EP1913015A1 (en) 2008-04-23
PL1913015T3 (pl) 2014-04-30
DK1913015T3 (en) 2014-03-10
AR057704A1 (es) 2007-12-12

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