PT1212089E - Combinacao sinergica de roflumilast e salmeterol - Google Patents

Combinacao sinergica de roflumilast e salmeterol

Info

Publication number
PT1212089E
PT1212089E PT00954625T PT00954625T PT1212089E PT 1212089 E PT1212089 E PT 1212089E PT 00954625 T PT00954625 T PT 00954625T PT 00954625 T PT00954625 T PT 00954625T PT 1212089 E PT1212089 E PT 1212089E
Authority
PT
Portugal
Prior art keywords
roflumilast
salmeterol
synergy combination
synergy
combination
Prior art date
Application number
PT00954625T
Other languages
English (en)
Inventor
Beume Rolf
Bundschuh Daniela
Armin Hatzelmann
Christian Schudt
Ulrich Kilian
Original Assignee
Altana Pharma Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Altana Pharma Ag filed Critical Altana Pharma Ag
Publication of PT1212089E publication Critical patent/PT1212089E/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/4015—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil having oxo groups directly attached to the heterocyclic ring, e.g. piracetam, ethosuximide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A61K31/522—Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
PT00954625T 1999-08-21 2000-08-11 Combinacao sinergica de roflumilast e salmeterol PT1212089E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP99116447 1999-08-21

Publications (1)

Publication Number Publication Date
PT1212089E true PT1212089E (pt) 2006-08-31

Family

ID=8238828

Family Applications (1)

Application Number Title Priority Date Filing Date
PT00954625T PT1212089E (pt) 1999-08-21 2000-08-11 Combinacao sinergica de roflumilast e salmeterol

Country Status (28)

Country Link
US (3) US7056936B2 (pt)
EP (3) EP2193808A1 (pt)
JP (1) JP5038568B2 (pt)
KR (1) KR100701904B1 (pt)
CN (1) CN1202865C (pt)
AT (2) ATE320800T1 (pt)
AU (1) AU777012B2 (pt)
BR (1) BRPI0013478B8 (pt)
CA (2) CA2715683A1 (pt)
CZ (1) CZ302882B6 (pt)
DE (2) DE60026855T2 (pt)
DK (1) DK1212089T3 (pt)
EA (1) EA006685B1 (pt)
ES (1) ES2260043T3 (pt)
HK (1) HK1047244B (pt)
HR (1) HRP20020158B1 (pt)
HU (1) HU229439B1 (pt)
IL (2) IL147688A0 (pt)
MX (1) MXPA02001830A (pt)
NO (1) NO328340B1 (pt)
NZ (1) NZ517166A (pt)
PL (1) PL200923B1 (pt)
PT (1) PT1212089E (pt)
SI (1) SI1212089T1 (pt)
SK (1) SK287231B6 (pt)
TR (2) TR200201317T2 (pt)
WO (1) WO2001013953A2 (pt)
ZA (1) ZA200201389B (pt)

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NO20020815D0 (no) 2002-02-19
CZ2002641A3 (cs) 2002-08-14
HRP20020158A2 (en) 2004-02-29
CA2381802A1 (en) 2001-03-01
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DE60026855D1 (de) 2006-05-11
EA200200208A1 (ru) 2002-08-29
NO20020815L (no) 2002-02-19
HUP0203098A3 (en) 2006-07-28
SK287231B6 (sk) 2010-04-07
HRP20020158B1 (en) 2007-08-31
AU777012B2 (en) 2004-09-30
PL200923B1 (pl) 2009-02-27
PL356252A1 (en) 2004-06-28
CN1370081A (zh) 2002-09-18
TR200909479T2 (tr) 2012-02-21
WO2001013953A2 (en) 2001-03-01
TR200201317T2 (tr) 2002-11-21
HK1047244A1 (en) 2003-02-14
JP5038568B2 (ja) 2012-10-03
SI1212089T1 (sl) 2006-08-31
HUP0203098A2 (hu) 2003-01-28
JP2003507435A (ja) 2003-02-25
MXPA02001830A (es) 2002-08-12
WO2001013953A3 (en) 2001-09-20
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IL147688A (en) 2007-09-20

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